TOTSUKA Mamoru

J-GLOBAL         Last updated: Feb 10, 2019 at 16:35
 
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Name
TOTSUKA Mamoru
Affiliation
Nippon Veterinary and Life Science University
Section
Department of Food Science and Technology, Faculty of Applied Life Science
Job title
Professor
Degree
Master of Agriculture(The University of Tokyo), Ph. D.(The University of Tokyo)

Research Areas

 
 

Academic & Professional Experience

 
Oct 2017
 - 
Today
Professor, Department of Food Science and Technology, Faculty of Applied Life Science, Nippon Veterinary and Life Science University
 
Apr 2006
 - 
Sep 2017
Associate Professor, Deparment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo
 
Aug 2009
 - 
Jul 2011
Senior Scientific Research Specialist, Ministry of Education, Culture, Sports, Science and Technology(MEXT)
 
Jun 1998
 - 
Mar 2006
Project Associate Professor, Deparment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo
 
Jun 1990
 - 
May 1998
Assistant Professor, Faculty of Agriculture, The University of Tokyo
 

Education

 
Apr 1988
 - 
May 1990
Department of Agricultural Chemistry, Graduate School of Agriculture, The University of Tokyo
 
Apr 1984
 - 
Mar 1988
Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo
 

Awards & Honors

 
2015
Japanese Association for Food Immunology Award, Japanese Association for Food Immunology
 
2010
The Excellent Paper Award Published in Bioscience, Biotechnology, & Biochemistry
 

Published Papers

 
Anserine/Carnosine Supplementation Preserves Blood Flow in the Prefrontal Brain of Elderly People Carrying APOE e4
Qiong Ding, Kitora Tanigawa, Jun Kaneko, Mamoru Totsuka, Yoshinori Katakura, Etsuko Imabayashi, Hiroshi Matsuda, Tatsuhiro Hisatsune
Aging and Disease   9(3) 334-345   Jun 2018   [Refereed]
A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs
Shin Murai, Yoshifumi Yamaguchi, Yoshitaka Shirasaki, Mai Yamagishi, Ryodai Shindo, Joanne Hildebrand, Ryosuke Miura, Osamu Nakabayashi, Mamoru Totsuka, Taichiro Tomida, Satomi Adachi-Akahane, Sotaro Uemura, John Silke, Hideo Yagita, Masayuki MIURA, and Hiroyasu Nakano
Nature Communications   9 4457   2018   [Refereed]
Katakura Yoshinori, Totsuka Mamoru, Imabayashi Etsuko, Matsuda Hiroshi, Hisatsune Tatsuhiro
NUTRIENTS   9(11)    Nov 2017   [Refereed]
Shin Hee Soon, Satsu Hideo, Bae Min-Jung, Totsuka Mamoru, Shimizu Makoto
NUTRIENTS   9(2)    Feb 2017   [Refereed]
Nakase Junpei, Ukawa Yuuichi, Takemoto Syoji, Kubo Takayoshi, Sagesaka Yuko M., Aoki-Yoshida Ayako, Totsuka Mamoru
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   81(6) 1099-1105   2017   [Refereed]

Misc

 
Effect of oral administration of Lactobacillus gasseri OLL2809 on the induction of oral tolerance
TOTSUKA Mamoru, AOKI-YOSHIDA Ayako
Clinical Immunology and Allergology   71(2) 138-145   Feb 2019   [Invited]
Satoshi Hachimura, Mamoru Totsuka, Akira Hosono
Bioscience, Biotechnology, and Biochemistry   82(4) 584-599   Jan 2018   [Refereed][Invited]
腸の構造と働き
戸塚 護
日本栄養士会雑誌   60(12) 654-656   Dec 2017   [Refereed][Invited]
腸管の機能とポリフェノール
清水 誠, 戸塚 護, 薩 秀夫
日本ポリフェノール学会雑誌   4(1) 30-36   Jul 2015   [Invited]
ポリフェノールの持つ機能は現在の特定保健用食品がカバーする領域には止まらない。ポリフェノールの機能を、腸管における作用に焦点を当て以下の項目に分けて述べた。1)特定保健用食品とポリフェノール、2)ポリフェノールによる腸管吸収機能の制御、3)腸管の解毒代謝機能とポリフェノール、4)腸の炎症とポリフェノール、5)分子標的を介したポリフェノールの抗炎症作用、として述べた。
Akiyama Hiroshi, Katayama Shigeru, Kanda Tomomasa, Maeda-Yamamoto Mari, Totsuka Mamoru, Takahashi Shingo, Shoji Toshihiko, Inakuma Takahiro, Nakamura Soichiro
CURRENT PHARMACEUTICAL DESIGN   20(6) 892-905   Feb 2014   [Refereed]

Books etc

 
Allergenicity of Milk Proteins
Shuichi Kaminogawa and Mamoru Totsuka (Part:Joint Work)
Advanced Dairy Chemistry Vol.1. Proteins 3rd Ed., Kluwer Academic / Plenum Publishers (New York, NY, USA)   2003   
Expression of a soluble αβ heterodimeric T cell receptor in animal cells. (共著)
Animal Cell Technology : Challenge for the 21st century   1999   
Manipulation of cytokine production from CD8+ T cells by means of amino acid-substituted analogs of a peptide antigen. (共著)
Animal Cell Technology : Challenge for the 21st century   1999   
Differential effect of antigen analogs with T cell inhibitory activity on in vivo antibody response. (共著)
Animal Cell Technology : Basic&Applied Aspects Klumer Academic Publishers   1998   
Antigen-specific inhibition of immune responses by antigen analogs with a single amino acid substitution (共著)
Animal Cell Technology: Basic & Applied Aspects Kluwer Academic Publishers   1997   

Conference Activities & Talks

 
Determination of immunoglobulin novel antigen receptor (IgNAR) in vivo affinity maturation in brownbanded bamboo shark (Chiloscyllium punctatum)
D.P.N. De Silva, S.Hosoya, N. Mizun1, S.Kinoshita, M. Totsuka and S. Asakawa
日本水産学会創立85周年記念国際シンポジウム   22 Sep 2017   日本水産学会
Immune modulatory effects of imidazole dipeptides [Invited]
Mamoru Totsuka
Special Lecture at Beijing Technology And Business University   18 Jul 2017   Beijing Technology And Business University
Modulatory effect of dietary phytochemicals on immune cells with immune-suppressive functions [Invited]
Mamoru Totsuka
Founding Meeting and the 1st academic meeting of Specialty Committee of Mongolia Medicine   14 Jul 2017   World Federation of Chinese Medicine Societies
Carnosine enhances intestinal IgA antibody production in mice
Cao Yuan, Junya Uchida, Yuichi Tsuda, Hideo Satsu, Makoto Shimizu, Mamoru Totsuka
The 2016 World Life Science Conference (WLSC2016)   1 Nov 2016   The China Association of Science and Technology (CAST) and the China Union of Life Science Societies
Enhancement of oral tolerance induction by probiotics: different immunosuppressive mechanisms by different probiotic strains [Invited]
Mamoru Totsuka
The 6th International Conference on Food Factors (ICoFF 2015) Symposium「Probiotics & Prebiotics」   22 Nov 2015   Korean Society of Food Science and Technology

Works

 
Study on primary response of naive T cells to altered peptide ligands.
1997
Study on the effect of dietary nucleotides on immune responses.
1998 - 2000
Manipulation of allergic reaction by altering primary structure of an allergen
1999
Study on immunological responses to microorganisms of intestinal epithelial cells.
2002

Research Grants & Projects

 
Antigen-specific modulation of immune responses by antigen analogs
Study on the Immune Response to Food Protein Antigens.
Study on antigen recognition by gut-associated lymphoid tissues
Screening of food factors modulating immune responses