Masao Sugawara

Profile Information

Degree: 理学博士(北海道大学)

Researcher number: 50002176
J-GLOBAL ID: 200901062229257440
researchmap Member ID: 1000013815

Research Interests

Research Areas

Nanotechnology/Materials / Analytical chemistry /

Research History

Apr, 1998

Department of Chemistry, College of Humanities and Sciences, Nihon University, Professor
Jul, 1992 - Mar, 1998

Department of Chemistry, Faculty of Science, University of Tokyo, Associate Professor
Apr, 1973 - Jun, 1992

Deparment of Chemsitry, Faculty of Science, Hokkaido University, Assistant Professor
Professor, Nihon University College of Humanities and Sciences, Department of Chemistry

Education

- Mar, 1973

Department of Chemsitry, Graduate School, Division of Science, Hokkaido University
- Mar, 1970

Department of Chemistry, Faculty of Science, Hokkaido University

Awards

Papers

Transmembrane Signaling with Lipid-Bilayer Assemblies as a Platform for Channel-Based Biosensing

Masao Sugawara

Chemical Record, 18(4) 433-444, Apr 1, 2018 Peer-reviewedInvited
Inhibitory assay for degradation of collagen IV by cathepsin B with a surface plasmon resonance sensor

A. Shoji, Y. Suenaga, A. Hosaka, Y. Ishida, A. Yanagida, M. Sugawara

J.Pharm. Biomed. Anal., 145 79-83, Jun, 2017 Peer-reviewed
Monitoring of chlesterol oxidation in a lipid bilayer membrane using sterptlysin O as a sensing and signal transduction element

A. Shoji, K. IKeya, M. Aoyagi, R. Takatsuji, A. Yanagida, Y. Shibusawa, M. Sugawara

J.Parm.Biomed.Anal., 128 455-461, Jul, 2016 Peer-reviewed
Visual Assay of Total Iron in Human Serum with Bathophenanthrolin Disulfonate-accommodated MCM-41

Misato Sakamoto, Keita Hizawa, Manabu Hosaka, Masao Sugawara

ANALYTICAL SCIENCES, 32(2) 241-244, Feb, 2016 Peer-reviewed
タンパク質及び神経阻害剤がガラスキャピラリー型L-グルタミン酸センサーの応答に及ぼす影響

池澤香奈, 菅澤隆之, 池上由季, 穂積志津子, 東海林敦, 菅原正雄

分析化学, 64(10) 743-750, Oct, 2015 Peer-reviewed
An Enzyme-entrapped Agarose Gel for Visualization of Ischemia-induced L-Glutamate Fluxes in Hippocampal Slices in a Flow System

Kazuhisa Tanaka, Atushi Shoji, Masao Sugawara

ANALYTICAL SCIENCES, 31(4) 321-325, Apr, 2015 Peer-reviewed
A solid phase-based nanopore sensing system for biomolecules using lipid-loaded mesoporous silica MCM-41 and a fluorescent dye

Ryo Takeuchi, Atsushi Shoji, Masao Sugawara

SENSORS AND ACTUATORS B-CHEMICAL, 181 29-37, May, 2013 Peer-reviewed
Implantable Patch Sensor for L-Glutamate in Hippocampal Slices

N. SOMA, N. WATANABE, A. SHOJI

Anal. Sci., 29(2) 181-185, Feb, 2013 Peer-reviewed
Planar Lipid Bilayers Containing Gramicidin A as a Molecular Sensing System Based on an Integrated Current

M. Nishio, A. Shouji

Anal. Sci., 28(7) 661-667, Jul, 2012 Peer-reviewed
Real-time monitoring of matrix metalloproteinase-9 collagenolytic activity with a surface plasmon resonance biosensor

Atsushi Shoji, Mitsutaka Kabeya, Masao Sugawara

ANALYTICAL BIOCHEMISTRY, 419(1) 53-60, Dec, 2011 Peer-reviewed
BSA-modified MCM-41 Channels in Planar Lipid Bilayers as a Sensing System for anti-BSA

Sensors and Actuators B: Chemical, 160 139-144, Nov, 2011 Peer-reviewed
Simultaneous Monitoring of Extracellular L-Glutamate Level and Excitatory Postsynaptic Potential in Region CA1 of Mouse Hippocampal Slices

S. Hozumi, K. Ikezawa, A. Shoji, A. Hirano-Iwata, T. Bliss, M. Sugawara

Biosensors&Bioelectronics, 26 2975-2980, Jan, 2011 Peer-reviewed
In Vitro Measurements of Extracellular L-Glutamate Level in Region CA3 of Mouse Hippocampal Slices under Chemical Stimulation

Hiromi CHIBA, Yukari DEGUCHI, Ena KANAZAWA, Jun KAWAI, Keiichiro NOZAWA, Atsushi SHOJI

Anal.Sci., 26(10) 1103-1106, Oct, 2010 Peer-reviewed
A reusable liposome array and its application to assay of growth-hormone-related peptides

Atsushi Shoji, Erika Sugimoto, Sayaka Orita, Keiichiro Nozawa, Akio Yanagida, Yoichi Shibusawa, Masao Sugawara

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 397(3) 1377-1381, Jun, 2010 Peer-reviewed
生体分子計測法の高度化と応用

東海林敦, 野澤桂一郎

日本大学自然科学研究所「研究紀要」, 45 353-362, Feb, 2010 Peer-reviewed
Trypsin-loaded mesoporous silica as a sensing material for amplified detection of ATP4-ions

K. Nozawa, A. Shoji, M. Sugawara

SUPRAMOLECULAR CHEMISTRY, 22(7-8) 389-395, 2010 Peer-reviewed
Comparison of the L-glutamate level in mouse hippocampal slices under tetraethylammonium chloride stimulation as measured with a glass capillary sensor and a patch sensor

Takayuki Oka, Yumiko Tominaga, Yuichiro Wakabayashi, Atsushi Shoji, Masao Sugawara

Analytical Sciences, 25(3) 353-358, Mar, 2009 Peer-reviewed
Visualizing L-glutamte Fluxes in Acute Brain Slices with Glutamate Oxidase-Immobilized Slips

Anal. Biochem., 385 326-333, 2009 Peer-reviewed
The design of molecular sensing interfaces with lipid-bilayer assemblies

Trends in Analytical Chemistry, 27(6) 515-520, 2008 Peer-reviewed
酵素膜プレートを用いて糖を色で測る

菅原正雄, 東海林敦

現代化学, 47-50, Oct, 2007

Misc.

A Planar Bilayer Lipid Membrane Sensor Using a Miniaturized Auto-patch System

Taiga Zamoto, Satoshi Tominaga, Masato Nishio, Atsushi Shoji, Masao Sugawara

ANALYTICAL SCIENCES, 33(12) 1421-1425, Dec, 2017 Peer-reviewed
Giant unilamellar vesicles containing Rhodamine 6G as a marker for immunoassay of bovine serum albumin and lipocalin-2

Misato Sakamoto, Atsushi Shoji, Masao Sugawara

ANALYTICAL BIOCHEMISTRY, 505 66-72, Jul, 2016 Peer-reviewed
Real-time monitoring of extracellular l-glutamate levels released by high-frequency stimulation at region CA1 of hippocampal slices with a glass capillary-based l-glutamate sensor

Yuki Ikegami, Shizuko Hozumi, Atsushi Shoji, Ayumi Hirano-Iwata, Tim Bliss, Masao Sugawara

Sensing and Bio-Sensing Research, 2 31-37, Dec 1, 2014 Peer-reviewed
Interference between field excitatory postsynaptic potentials and simultaneously recorded chronoamperometric L-glutamate currents in mouse hippocampal slices

Ayumi Hirano-Iwata, Ryosuke Matsumura, Ryuta Tezuka, Michio Niwano, Tim V. P. Bliss, Masao Sugawara

ELECTROCHEMISTRY COMMUNICATIONS, 45 1-4, Aug, 2014 Peer-reviewed
Evaluation of cathepsin B activity for degrading collagen IV using a surface plasmon resonance method and circular dichroism spectroscopy

Atsushi Shoji, Mitsutaka Kabeya, Yuuki Ishida, Akio Yanagida, Yoichi Shibusawa, Masao Sugawara

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 95 47-53, Jul, 2014 Peer-reviewed
Pore-forming Compounds as Signal Transduction Elements for Highly Sensitive Biosensing

Masao Sugawara, Atsushi Shoji, Misato Sakamoto

ANALYTICAL SCIENCES, 30(1) 119-128, Jan, 2014 Peer-reviewedInvited
Highly Sensitive and Rapid Assay of Substance P and Streptolysin O in Human Serum Using Immuno-liposomes and Gramicidin Channels

Misato Sakamoto, Atsushi Shoji, Masao Sugawara

ANALYTICAL SCIENCES, 29(9) 877-883, Sep, 2013 Peer-reviewed

Books and Other Publications

Chapter 6 Design of liposomes with a pH-sensitive fluorescent dye and gramicidin channels for immune-sensing in "Advances in Liposome Researches"

A. Shoji, M. Sakamoto, M. Sugawara

Nova Science Publishers, New York (2014), Mar, 2014
バイオセンサの先端的技術と新製品への応用開発

菅原正雄

(株)技術情報協会, 2014
Microsensors

A.Shoji (Role: Joint author, pp 204-216)

Intech, Jun, 2011 (ISBN: 9789533071701)
新版基礎分析化学演習

三共出版, Apr 10, 2010
Design and Application of planar bilayer lipid membranes containing biological ion channels for chemical sensing

(Role: Joint author)

Advances in Planar Bilyers and Liposomes, Vol. 1, Chapter 8, Edited by H. T. Tien and A. Ottova-Leitmannova, Elsevier, 2005
基礎分析化学演習

菅原正雄

三共出版, 2004
基本分析化学(分担執筆）

(Role: Joint author)

朝倉書店, 2004
イラストで見る化学実験の基礎知識(共著）

(Role: Joint author)

丸善, 2003
理工系機器分析の基礎(分担執筆)

2001

Presentations

表面プラズモン共鳴法を用いたカテプシン B によるコラーゲン IV 分解反応の評価

東海林敦, 壁谷充尭, 石田裕樹, 菅原正雄

日本分析化学会第６３年会, Sep 19, 2014, 日本分析化学会
ジャイアントリポソーム（GUVs）を用いたパッチセンサーの開発

福田裕之, 坂本美里, 渡部成美, 菅原正雄

日本分析化学会第６３年会, Sep 19, 2014, 日本分析化学会
海馬CA1領域の高頻度刺激時に放出されるグルタミン酸の計測

渡部成美, 池上由季, 穂積志津子, 東海林敦, 平野愛弓, 菅原正雄

日本分析化学会第６３年会大阪、, Sep 18, 2014, 日本分析化学会
マウス脳スライス内におけるグルタミン酸電流に及ぼす興奮性後シナプス電位の影響

平野愛弓, 松村亮佑, 菅原正雄, 庭野道夫

日本分析化学会第６３年会, Sep 18, 2014, 日本分析化学会
脂質二分子膜内ステロールの酸化反応評価法に関する基礎検討

池谷佳奈, 青柳美紀, 高辻龍太郎, 柿崎郁美, 東海林敦, 柳田顕郎, 渋澤庸一, 菅原正雄

第27回バイオメディカル分析科学シンポジウム（BMAS2014）, Aug 20, 2014, バイオメディカル分析科学会
コラーゲン IV を用いるカテプシン B 阻害活性の評価：表面プラズモン共鳴法の適用

石田裕樹, 渡部成美, 東海林敦

日本分析化学会第６２年会, Sep 12, 2013
安定な脂質二分子膜の形成とバイオセンシングへの応用

西尾将人, 中山信広, 菅原正雄, 森清昭

第73回分析化学討論会, May 9, 2013, 日本分析化学会
超高感度リポソームイムノアッセイによる血清中のサブスタンスPの定量

東海林敦, 阪本美里, 菅原正雄

日本薬学会第133年会, Mar 29, 2013, 日本薬学会
ガラスキャピラリー内への脂質二分子膜のパターニングとセンシングへの応用

大里沙紀, 東海林敦

第５６回日本薬学会関東支部大会, Oct 13, 2012, 日本薬学会関東支部
急性海馬スライスから放出されるグルタミン酸のフロー系イメージング法

田中和久, 東海林敦

第５６回日本薬学会関東支部大会, Oct 13, 2012, 日本薬学会関東支部
脳スライス内グルタミン酸放出の時間変化とその放出量の高精度解析

手塚竜太, 平野愛弓, 庭野道夫

日本分析化学会第６１年会, Sep 21, 2012, 日本分析化学会
海馬スライスCA1領域での長期増強現象におけるグルタミン酸の役割の検討

穂積志津子, 池上由季, 東海林敦, 平野愛弓, T. Bliss

日本分析化学会第６１年会, Sep 21, 2012, 日本分析化学会
グルタミン酸酸化酵素を封入したアガロース膜を用いたフロー系イメージング法の開発

田中和久, 東海林敦

日本分析化学会第６１年会, Sep 21, 2012, 日本分析化学会
血清中サブスタンスPの高感度イムノアッセイ法の構築

阪本美里, 東海林敦

日本分析化学会第６１年会, Sep 21, 2012, 日本分析化学会
表面プラズモン共鳴法による 3 本鎖らせん構造を有するコラーゲン IV 分解反応のリアルタイムモニタリング

東海林敦, 壁谷充尭

日本分析化学会第６１年会, Sep 20, 2012
界面スライスを対象とする埋め込みパッチセンサーの開発

相馬奈都美, 穂積志津子, 東海林敦, 菅原正雄

日本分析化学会第60年会, Sep 15, 2011, 日本分析化学会
グルタミン酸濃度と興奮性シナプス後電位の同時計測：長期増強現象とグルタミン酸濃度の関係

穂積志津子, 東海林敦, 菅原正雄

日本分析化学会第60年会, Sep 15, 2011, 日本分析化学会
グラミシジンを包埋したイムノリポソーム凝集体によるサブスタンスPの超高感度イムノアッセイ

阪本美里, 東海林敦, 菅原正雄

日本分析化学会第60年会, Sep 15, 2011
Real time measurements of matrix metalloproteinase-9 activity by surface plasmon resonance method

A. Shoji, M. Kabeya, M. Sugawara

IUPAC international congress on analytical sciences, Kyoto, May 23, 2011, IUPAC
表面プラズモン共鳴法を用いたMatrix Metalloproteinase-9阻害活性測定法の構築

壁谷充尭, 東海林敦, 野澤桂一郎

日本分析化学会第59年会, Sep 17, 2010, 日本分析化学会

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