Kenji Takahashi - My portal - researchmap

Profile Information

Affiliation: Former Institution /Organization Laboratory of Molecular Biochemistry

Degree: Doctor of Science(The University of Tokyo)
Master of Science(The University of Tokyo)

J-GLOBAL ID: 200901044508409686
researchmap Member ID: 1000013846

Research Interests

2

Research Areas

1

Life sciences / Structural biochemistry /

Research History

13

1995 - 2005

Tokyo University of Pharmacy and Life Sciences
1995 - 2005

Tokyo University of Pharmacy and Life Science
1984 - 1995

The University of Tokyo
1984 - 1995

The University of Tokyo, Professor
1974 - 1984

京都大学教授
1974 - 1984

Kyoto University, Professor
1973 - 1973

The University of Tokyo
1973 - 1973

The University of Tokyo, Lecturer
1963 - 1973

The University of Tokyo
1963 - 1973

The University of Tokyo, Assistant
1962 - 1963

日本学術振興会奨励研究生
1962 - 1963

Japan Society for the Promotion
of Science, Postdoctoral Fellow

Education

4

- 1962

The University of Tokyo
- 1962

Graduate School, Division of Science, The University of Tokyo
- 1957

Faculty of Science, The University of Tokyo
- 1957

Chemistry, Faculty of Science, The University of Tokyo

Committee Memberships

1

1953 - 1954

編集委員、評議員／参与, 日本生化学会

Awards

1

1965

日本生化学会奨励賞

Misc.

87

Specific inhibition and stabilization of aspergilloglutamic peptidase by the propeptide - Identification of critical sequences and residues in the propeptide

K Kubota, W Nishii, M Kojima, K Takahashi

JOURNAL OF BIOLOGICAL CHEMISTRY, 280(2) 999-1006, Jan, 2005
Thermal unfolding of ribonuclease T1 studied by multidimensional NMR spectroscopy

H Matsuura, S Shimotakahara, C Sakuma, M Tashiro, H Shindo, K Mochizuki, A Yamagishi, M Kojima, K Takahashi

BIOLOGICAL CHEMISTRY, 385(12) 1157-1164, Dec, 2004
Identification of a glutamine residue essential for catalytic activity of aspergilloglutamic peptidase by site-directed mutagenesis

Y Yabuki, K Kubota, M Kojima, H Inoue, K Takahashi

FEBS LETTERS, 569(1-3) 161-164, Jul, 2004
The Three-dimensional Structure of Aspergilloglutamic Peptidase from Aspergillus niger 'jointly worked'

Hiroshi SASAKI, Atsushi NAKAGAWA, Tomonari MURAMATSU, Megumi SUGANUMA, Yoriko SAWANO, Masaki KOJIMA, Keiko KUBOTA, Kenji TAKAHASHI, Masaru TANOKURA

Proceedings of the Japan Academy, Ser.B, 80(9) 435-438, 2004
Cathepsin L-Like Cysteine Proteases from Brugia malayi : cDNA Cloning and Comparison with Caenorhabditis elegans 'jointly worked'

Biomedical Research, in press, 2004
Identification of Arginine Residues Important for the Activity of Escherichia coli Signal Peptidase I 'jointly worked'

Biological Chemistry, 385 381-388, 2004
Two distinct types of aspartic proteases in the filarial parasite Brugia malayi: Molecular cloning and tissue distribution

SBP Athauda, H Nomura, H Inoue, K Takahashi

BIOMEDICAL RESEARCH-TOKYO, 24(5) 269-276, Oct, 2003
Determination of the NMR structure of Gln25-ribonuclease T1

Ken-Ichi Hatano, Masaki Kojima, Ei-Ichiro Suzuki, Masaru Tanokura, Kenji Takahashi

Biological Chemistry, 384(8) 1173-1183, Aug 1, 2003
The Physarum polycephalum php gene encodes a unique cold-adapted serine-carboxyl peptidase, physarolisin II

W Nishii, H Kuriyama, K Takahashi

FEBS LETTERS, 546(2-3) 340-344, Jul, 2003
Inhibition of human pepsin and gastricsin by alpha(2)-macroglobulin

SBP Athauda, M Nishigai, H Arakawa, A Ikai, M Ukai, K Takahashi

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 18(3) 219-224, May, 2003
Kinetic studies of unfolding process of aspergillopepsin II by pH-jump methods

M Maeda, K Takeuchi, M Kojima, M Tanokura, K Kimura, Y Amemiya, H Kihara, K Takahashi

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 301(3) 745-750, Feb, 2003
Determination of the Clearage Sites in SulA, a Cell Division Inhibitor, by the ATP-dependent HsLⅤⅤ Protease from Escherichia coli

FEBS Letters 553, 351-354, 553(3) 351-354, 2003
Structural and Enzymatic Characterization of Physarolisin (Formerly Physaropepsin) Proves That It is a Unique Serine-Carboxyl Proteinase (jointly worked)

Biochemical and Biophysical Research Communications, 301(4) 1023-1029, 2003
Nuclear magnetic resonance studies on the pKa values and interaction of ionizable groups in bromelain inhibitor VI from pineapple stem

Ken-Ichi Hatano, Masaki Kojima, Masaru Tanokura, Kenji Takahashi

Biological Chemistry, 384(1) 93-104, Jan 1, 2003
Limited Proteolysis of α₂-Macroglobulin by Cathepsin D and Structural Changes in the Inhibitor (jointly worked)

Biomedical Research, 23(4) 199-201, 2002
Cleavage Specificities of Aspartic Proteinases toward Oxidized Insulin B Chain at Different pH Values（共著）

Protein and Peptide Letters, 9(4), 289-294, 2002
Reverse Genetic Analysis of the Caenorhabditis elegans 26S Proteasome Subunits by RNA Interference

Biological Chemistry, 383, 1263-1266, 2002
In Situ Visualization of Caspase-1-like Activity Associated with Promotion of Hippocampal Cell Death（共著）

FEBS Letters, 518, 149-153, 2002
Distinct Cleavage Specificity of Human Cathepsin E at Neutral pH with Special Preference for Arg-Arg Bonds（共著）

Protein and Peptide Letters, 9(1), 15-22, 2002
The Unique Sites in Sul A Protein Preferentially Cleaved by ATP-dependent Lon Protease from Escherichia coli（共著）

European Journal of Biochemistry, 269, 451-456, 2002

More

Professional Memberships

4

Works

2

フィラリア症寄生虫プロテアーゼの性状と阻害剤の研究

1996 - 2001
Study on Properties and Inhibitors of Filarial Proteases

1996 - 2001

Research Projects

6