堀内三吉 (Sankichi Horiuchi) - マイポータル - researchmap

基本情報

所属: 旧所属東京医科歯科大学大学院医歯学総合研究科生体環境応答学系専攻感染応答学講座講師

学位: 医学博士

J-GLOBAL ID: 200901041863201558
researchmap会員ID: 1000014164

研究キーワード

6

研究分野

2

経歴

4

1968年 - 1994年

東京医科歯科大学医学部微生物学教室助手
1968年 - 1994年

Department of Microbiology, Tokyo Medical and Dental University, Assistant professor
1994年

- 東京医科歯科大学ウイルス制御学講師
1994年

- Department of Molecular Virology, Tokyo Medical and Dental University, Lecturer

学歴

2

- 1966年

東京理科大学, 理学部, 化学
- 1966年

東京理科大学

MISC

30

Soluble IL-6 receptor governs IL-6 activity in experimental arthritis: Blockade of arthritis severity by soluble glycoprotein 130

MA Nowell, PJ Richards, S Horiuchi, N Yamamoto, S Rose-John, N Topley, AS Williams, SA Jones

JOURNAL OF IMMUNOLOGY 171(6) 3202-3209 2003年9月
IL-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation

SM Hurst, TS Wilkinson, RM McLoughlin, S Jones, S Horiuchi, N Yamamoto, S Rose-John, GM Fuller, N Topley, SA Jones

IMMUNITY 14(6) 705-714 2001年6月
Enhanced expression of mRNAs of antisecretory factor-1, gp96, DAD1 and CDC34 in human hepatocellular carcinomas

K Tanaka, N Kondoh, M Shuda, O Matsubara, N Imazeki, A Ryo, T Wakatsuki, A Hada, N Goseki, T Igari …

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1536(1) 1-12 2001年4月
The soluble interleukin 6 receptor: mechanisms of production and implications in disease

SA Jones, S Horiuchi, N Topley, N Yamamoto, GM Fuller

FASEB JOURNAL 15(1) 43-58 2001年1月
Enhanced expression of translation factor mRNAs in hepatocellular carcinoma

M Shuda, N Kondoh, K Tanka, A Ryo, T Wakatsuki, A Hada, N Goseki, T Igari, K Hatsuse, T Aihara …

ANTICANCER RESEARCH 20(4) 2489-2494 2000年7月
Identification and Characterization of Genes Associated with Human Hepatocellular Carcinogenesis

Cancer Research 59 4900-4996 1999年
C-reactive protein : A physiological Activator of Interleukin 6 Receptor shedding

J. Exp. Med 189(3) 599-604 1999年
Shedding of the soluble IL-6 receptor is triggered by Ca²⁺ mobilization, while basal release is predominantly product of differential mRNA splicing in THP-1 cells.

Eur. J. Immunol. 1998年
High level production of alternatively spliced soluble interleukin-6 receptor in serum of patients with adult T-cell leukemia/HTLV-1 associated myelopathy

Immunology 1998年
Elevated serum levels of the soluble form of gp130, the IL-6 signal transducer, in HTLV-1 infection and no involvement of alternative splicing for its generation

YW Zhou, S Horiuchi, M Yamamoto, N Yamamoto

MICROBIOLOGY AND IMMUNOLOGY 42(2) 109-116 1998年
Antisense oligonucleotides to p53 tumor suppressor suppress the induction of apoptosis by epidermal growth factor in NCI-H 596 human lung cancer cells

Y Murayama, S Horiuchi

ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT 7(2) 109-114 1997年4月
可溶性IL-6 セプターの産生機構

臨床免疫 29(11) 1328-1336 1997年
Altered interleukin-2 receptor α-chain is expressed in human T-cell leukaemia virus type-1-infected T-cell lines and human peripheral blood mononuclear cells of adult T-cell leukaemia patients through an alternative splicing mechanism

Immunology 91(1) 28-34 1997年
Synthesis of Protegrin-Related Peptides and Their Antibacterial and Anti-human Immunodeficiency Virus Activity ¹⁾

Hirokazu TAMAMURA, Tsutomu MURAKAMI, Sankichi HORIUCHI, Keiji SUGIHARA, Akira OTAKA, Wataru TAKADA, Toshiro IBUKA, Michinori WAKI, Naoki YAMAMOTO, Nobutaka FUJII

Chem. Pharm. Bull. 43(5) 853-858 1995年
Soluble interleukin-6 receptors released from T-cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism

Eur. J. Immunol. 24(8) 1945-1948 1994年
Soluble interleukin-6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism^*

Eur. J. Immunol 24(8) 1945-1948 1994年
REDUCED SUSCEPTIBILITIES OF SHIGELLA-SONNEI STRAINS ISOLATED FROM PATIENTS WITH DYSENTERY TO FLUOROQUINOLONES

S HORIUCHI, Y INAGAKI, N YAMAMOTO, N OKAMURA, Y IMAGAWA, R NAKAYA

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 37(11) 2486-2489 1993年11月
リジン脱炭酸反応陰性サルモネラ血清型Paratyphi βによる大規模な食中毒事例

東京都立衛生研究所研究年報 44,3-11 1993年
CAMP stimulates human immunodeficiency virus(HIV-1) from latently infected cells of monocyte-macrophage lineage : Synergism with TNF-α.

Virology 194,345-349 1993年
Reduced susceptibilities of ┣DBShigella(/)-┫DB ┣DBsonnei(/)-┫DB strains isolated from patients with dysentery to fluoroquinolones.

Antimicrobial Agents and Chemotherapy 37(11) 2486-2489 1993年

もっとみる

所属学協会

4

Works(作品等)

2

可溶性インターロイキン6レセプター

1997年
Soluble interleukin-6 receptor

1997年

共同研究・競争的資金等の研究課題

6