成相直 (Tadashi Nariai) - マイポータル

基本情報

所属: 東京医科歯科大学大学院医歯学総合研究科脳神経機能外科学分野准教授

学位: 医学博士
MD

J-GLOBAL ID: 200901045081133958
researchmap会員ID: 1000014359

研究キーワード

研究分野

経歴

2013年3月 - 現在

東京医科歯科大学大学院医歯学総合研究科, 脳神経機能外科学分野, 准教授
2002年 - 現在

Visiting Scientist, Brain Imaging Project, National Institute of Radiological Science
1995年 - 現在

東京都健康長寿医療センター研究所客員研究員
1995年 - 現在

Visiting Scientist, Positron Medical Center, Tokyo Metropolitan Institute of Gerontology,
1990年 - 現在

Assistant Professor, Department of Neurosurgery, Tokyo Medical and Dental University
2001年4月 - 2013年2月

東京医科歯科大学脳神経外科講師
1990年 - 2001年

東京医科歯科大学脳神経外科助手
1988年 - 1990年

米国国立衛生研究所客員研究員
1988年 - 1990年

Visiting Fellow, NIA, NIH, USA

学歴

- 1984年

東京医科歯科大学, 医学部, 医学科
- 1984年

東京医科歯科大学

委員歴

受賞

論文

Independent predictors of shunt-dependent normal pressure hydrocephalus after aneurysmal subarachnoid hemorrhage

Takashi Sugawara, Taketoshi Maehara, Tadashi Nariai, Masaru Aoyagi, Kikvo Ohno

Journal of Neurosurgical Sciences 60(2) 154-158 2016年査読有り
Validity of Prognostic Grading Indices for Brain Metastasis Patients Undergoing Repeat Radiosurgery

Masaaki Yamamoto, Takuya Kawabe, Yoshinori Higuchi, Yasunori Sato, Tadashi Nariai, Shinya Watanabe, Bierta E. Barfod, Hidetoshi Kasuya

WORLD NEUROSURGERY 82(6) 1242-1249 2014年12月査読有り
Stereotactic radiosurgery for patients with multiple brain metastases: a case-matched study comparing treatment results for patients with 2-9 versus 10 or more tumors

Masaaki Yamamoto, Takuya Kawabe, Yasunori Sato, Yoshinori Higuchi, Tadashi Nariai, Shinya Watanabe, Hidetoshi Kasuya

JOURNAL OF NEUROSURGERY 121 16-25 2014年12月査読有り
Clinical Benefit of C-11 Methionine PET Imaging as a Planning Modality for Radiosurgery of Previously Irradiated Recurrent Brain Metastases

Toshiya Momose, Tadashi Nariai, Takuya Kawabe, Motoki Inaji, Yoji Tanaka, Shinya Watanabe, Taketoshi Maehara, Keiichi Oda, Kenji Ishii, Kiichi Ishiwata …

CLINICAL NUCLEAR MEDICINE 39(11) 939-943 2014年11月査読有り
Changes in cerebral blood flow during steady-state cycling exercise: a study using oxygen-15-labeled water with PET

Mikio Hiura, Tadashi Nariai, Kenji Ishii, Muneyuki Sakata, Keiichi Oda, Jun Toyohara, Kiichi Ishiwata

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 34(3) 389-396 2014年3月査読有り
Practical Clinical Use of Dynamic Susceptibility Contrast Magnetic Resonance Imaging for the Surgical Treatment of Moyamoya Disease

Yosuke Ishii, Tadashi Nariai, Yoji Tanaka, Maki Mukawa, Motoki Inaji Md, Taketoshi Maehara, Kikuo Ohno

NEUROSURGERY 74(3) 302-309 2014年3月査読有り
Clinical features of familial juvenile cases of moyamoya disease: analysis of patients treated in a single institute over a 28-year period

Maki Mukawa, Tadashi Nariai, Yoshiharu Matsushima, Kikuo Ohno

JOURNAL OF NEUROSURGERY-PEDIATRICS 12(2) 175-180 2013年8月査読有り
Dynamic Neural Network Reorganization Associated with Second Language Vocabulary Acquisition: A Multimodal Imaging Study

Chihiro Hosoda, Kanji Tanaka, Tadashi Nariai, Manabu Honda, Takashi Hanakawa

JOURNAL OF NEUROSCIENCE 33(34) 13663-+ 2013年8月査読有り
A case-matched study of stereotactic radiosurgery for patients with multiple brain metastases: comparing treatment results for 1-4 vs ≥ 5 tumors: clinical article.

Yamamoto M, Kawabe T, Sato Y, Higuchi Y, Nariai T, Barfod BE, Kasuya H, Urakawa Y

Journal of neurosurgery 118(6) 1258-1268 2013年6月査読有り
Direct comparison of radiation dosimetry of six PET tracers using human whole-body imaging and murine biodistribution studies

Muneyuki Sakata, Keiichi Oda, Jun Toyohara, Kenji Ishii, Tadashi Nariai, Kiichi Ishiwata

ANNALS OF NUCLEAR MEDICINE 27(3) 285-296 2013年4月査読有り
Delayed complications in patients surviving at least 3 years after stereotactic radiosurgery for brain metastases.

Yamamoto M, Kawabe T, Higuchi Y, Sato Y, Nariai T, Barfod BE, Kasuya H, Urakawa Y

International journal of radiation oncology, biology, physics 85(1) 53-60 2013年1月1日査読有り
A selective adenosine A2A receptor antagonist ameliorated hyperlocomotion in an animal model of lateral fluid percussion brain injury.

Mullah SH, Inaji M, Nariai T, Ishibashi S, Ohno K

Acta neurochirurgica. Supplement 118 89-92 2013年査読有り
PET molecular imaging to investigate higher brain dysfunction in patients with neurotrauma.

Nariai T, Inaji M, Tanaka Y, Hiura M, Hosoda C, Ishii K, Ohno K

Acta neurochirurgica. Supplement 118 251-254 2013年査読有り
Increased Adenosine A(1) Receptor Levels in Hemianopia Patients After Cerebral Injury An Application of PET Using C-11-8-Dicyclopropylmethyl-1-Methyl-3-Propylxanthine

Yukihisa Suzuki, Tadashi Nariai, Motohiro Kiyosawa, Manabu Mochizuki, Yuichi Kimura, Keiichi Oda, Kenji Ishii, Kiich Ishiwata

CLINICAL NUCLEAR MEDICINE 37(12) 1146-1151 2012年12月査読有り
Long-term follow-up of surgically treated juvenile patients with moyamoya disease Clinical article

Maki Mukawa, Tadashi Nariai, Yoshiharu Matsushima, Yoji Tanaka, Motoki Inaji, Taketoshi Maehara, Masaru Aoyagi, Kikuo Ohno

JOURNAL OF NEUROSURGERY-PEDIATRICS 10(5) 451-456 2012年11月査読有り
The effects of professional oral health care on patients in the subacute stage of emergent neurosurgical disorders

Chisato Mori, Chiyoko Hakuta, Keiko Endo, Tadashi Nariai, Masayuki Ueno, Kayoko Shinada, Yoko Kawaguchi

Special Care in Dentistry 32(6) 259-264 2012年11月査読有り
OPTICAL ANALYSIS OF DEVELOPMENTAL CHANGES IN SYNAPTIC POTENTIATION IN THE NEONATAL RAT CORTICOSTRIATAL PROJECTION

S. H. -E. -R. Mullah, M. Inaji, T. Nariai, Y. Momose-Sato, K. Sato, K. Ohno

NEUROSCIENCE 201 338-348 2012年1月査読有り
Comparison of the Kinetics of Pulmonary Oxygen Uptake and Middle Cerebral Artery Blood Flow Velocity During Cycling Exercise

Mikio Hiura, Norimitsu Kinoshita, Sigeki Izumi, Tadashi Nariai

OXYGEN TRANSPORT TO TISSUE XXXIII 737 25-31 2012年査読有り
The status of Tsukuba BNCT trial: BPA-based boron neutron capture therapy combined with X-ray irradiation

T. Yamamoto, K. Nakai, T. Nariai, H. Kumada, T. Okumura, M. Mizumoto, K. Tsuboi, A. Zaboronok, E. Ishikawa, H. Aiyama …

APPLIED RADIATION AND ISOTOPES 69(12) 1817-1818 2011年12月査読有り
A clinical trial protocol for second line treatment of malignant brain tumors with BNCT at University of Tsukuba

H. Aiyama, K. Nakai, T. Yamamoto, T. Nariai, H. Kumada, E. Ishikawa, T. Isobe, K. Endo, T. Takada, F. Yoshida …

APPLIED RADIATION AND ISOTOPES 69(12) 1819-1822 2011年12月査読有り

もっとみる

MISC

Correlation between focal brain metabolism and higher brain function in patients with Moyamoya disease

Chihiro Hosoda, Tadashi Nariai, Kiichi Ishiwata, Kenji Ishii, Yoshiharu Matsushima, Kikuo Ohno

INTERNATIONAL JOURNAL OF STROKE 5(5) 367-373 2010年10月
Glial Cell-Mediated Deterioration and Repair of the Nervous System after Traumatic Brain Injury in a Rat Model as Assessed by Positron Emission Tomography

Iwae Yu, Motoki Inaji, Jun Maeda, Takashi Okauchi, Tadashi Nariai, Kikuo Ohno, Makoto Higuchi, Tetsuya Suhara

JOURNAL OF NEUROTRAUMA 27(8) 1463-1475 2010年8月
Accumulation of CD 133-positive glioma cells after high-dose irradiation by Gamma Knife surgery plus external beam radiation Clinical article

Kaoru Tamura, Masaru Aoyagi, Hiroaki Wakimoto, Noboru Ando, Tadashi Nariai, Masaaki Yamamoto, Kikuo Ohno

JOURNAL OF NEUROSURGERY 113(2) 310-318 2010年8月
PET pharmacokinetic analysis to estimate boron concentration in tumor and brain as a guide to plan BNCT for malignant cerebral glioma

Tadashi Nariai, Kiichi Ishiwata, Yuichi Kimura, Motoki Inaji, Toshiya Momose, Tetsuya Yamamoto, Akira Matsumura, Kenji Ishii, Kikuo Ohno

APPLIED RADIATION AND ISOTOPES 67(7-8) S348-S350 2009年7月
Contributions of biological tumor parameters to the incorporation rate of l-[methyl-C-11] methionine into astrocytomas and oligodendrogliomas

Takeko Nojiri, Tadashi Nariai, Masaru Aoyagi, Michio Senda, Kenji Ishii, Kiichi Ishiwata, Kikuo Ohno

JOURNAL OF NEURO-ONCOLOGY 93(2) 233-241 2009年6月
Contributions of biological tumor parameters to the incorporation rate of l-[methyl-C-11] methionine into astrocytomas and oligodendrogliomas

Takeko Nojiri, Tadashi Nariai, Masaru Aoyagi, Michio Senda, Kenji Ishii, Kiichi Ishiwata, Kikuo Ohno

JOURNAL OF NEURO-ONCOLOGY 93(2) 233-241 2009年6月
Glioma surgery using a multimodal navigation system with integrated metabolic images

Yoji Tanaka, Tadashi Nariai, Toshiya Momose, Masaru Aoyagi, Taketoshi Maehara, Toshiki Tomori, Yoshikazu Yoshino, Tsukasa Nagaoka, Kiichi Ishiwata, Kenji Ishii …

JOURNAL OF NEUROSURGERY 110(1) 163-172 2009年1月
Glioma surgery using a multimodal navigation system with integrated metabolic images

Yoji Tanaka, Tadashi Nariai, Toshiya Momose, Masaru Aoyagi, Taketoshi Maehara, Toshiki Tomori, Yoshikazu Yoshino, Tsukasa Nagaoka, Kiichi Ishiwata, Kenji Ishii …

JOURNAL OF NEUROSURGERY 110(1) 163-172 2009年1月
Voxel- and ROI-based statistical analyses of PET parameters for guidance in the surgical treatment of intractable mesial temporal lobe epilepsy

Yoshihisa Ohta, Tadashi Nariai, Kenji Ishii, Kiichi Ishiwata, Masahiro Mishina, Michio Senda, Kimiyoshi Hirakawa, Kikuo Ohno

ANNALS OF NUCLEAR MEDICINE 22(6) 495-503 2008年7月
Voxel- and ROI-based statistical analyses of PET parameters for guidance in the surgical treatment of intractable mesial temporal lobe epilepsy

Yoshihisa Ohta, Tadashi Nariai, Kenji Ishii, Kiichi Ishiwata, Masahiro Mishina, Michio Senda, Kimiyoshi Hirakawa, Kikuo Ohno

ANNALS OF NUCLEAR MEDICINE 22(6) 495-503 2008年7月
Measurement of the C-11-flumazenil binding in the visual cortex predicts the prognosis of hemianopia

Yukihisa Suzuki, Chiharu Horie, Motohiro Kiyosawa, Tadashi Nariai, Manabu Mochizuki, Keiichi Oda, Yuichi Kimura, Kiich Ishiwata, Kenji Ishii

JOURNAL OF THE NEUROLOGICAL SCIENCES 268(1-2) 102-107 2008年5月
Measurement of the C-11-flumazenil binding in the visual cortex predicts the prognosis of hemianopia

Yukihisa Suzuki, Chiharu Horie, Motohiro Kiyosawa, Tadashi Nariai, Manabu Mochizuki, Keiichi Oda, Yuichi Kimura, Kiich Ishiwata, Kenji Ishii

JOURNAL OF THE NEUROLOGICAL SCIENCES 268(1-2) 102-107 2008年5月
Quantitative evaluation of cerebral hemodynamics in patients with moyamoya disease by dynamic susceptibility contrast magnetic resonance imaging - comparison with positron emission tomography

Y Tanaka, T Nariai, T Nagaoka, H Akimoto, K Ishiwata, K Ishii, Y Matsushima, K Ohno

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 26(2) 291-300 2006年2月
Quantitative evaluation of cerebral hemodynamics in patients with moyamoya disease by dynamic susceptibility contrast magnetic resonance imaging - comparison with positron emission tomography

Y Tanaka, T Nariai, T Nagaoka, H Akimoto, K Ishiwata, K Ishii, Y Matsushima, K Ohno

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 26(2) 291-300 2006年2月
Imaging of somatotopic representation of sensory cortex with intrinsic optical signals as guides for brain tumor surgery

Tadashi Nariai, Katsushige Sato, Kimiyoshi Hirakawa, Yoshihisa Ohta, Yoji Tanaka, Kiichi Ishiwata, Kenji Ishii, Kohtaro Kamino, Kikuo Ohno

Journal of Neurosurgery 103(3) 414-423 2005年9月
Usefulness Of L-[methyl-(11)C] methionine-positron emission tomography as a biological monitoring tool in the treatment of glioma

T Nariai, Y Tanaka, H Wakimoto, M Aoyagi, M Tamaki, K Ishiwata, M Senda, K Ishii, K Hirakawa, K Ohno

JOURNAL OF NEUROSURGERY 103(3) 498-507 2005年9月
Usefulness Of L-[methyl-(11)C] methionine-positron emission tomography as a biological monitoring tool in the treatment of glioma

T Nariai, Y Tanaka, H Wakimoto, M Aoyagi, M Tamaki, K Ishiwata, M Senda, K Ishii, K Hirakawa, K Ohno

JOURNAL OF NEUROSURGERY 103(3) 498-507 2005年9月
Omission of serial arterial blood sampling in neuroreceptor imaging with independent component analysis

M Naganawa, Y Kimura, T Nariai, K Ishii, K Oda, Y Manabe, K Chihara, K Ishiwata

NEUROIMAGE 26(3) 885-890 2005年7月
Omission of serial arterial blood sampling in neuroreceptor imaging with independent component analysis

M Naganawa, Y Kimura, T Nariai, K Ishii, K Oda, Y Manabe, K Chihara, K Ishiwata

NEUROIMAGE 26(3) 885-890 2005年7月
Functional representation of the ringer and face in the human somatosensory cortex: intraoperative intrinsic optical imaging

K Sato, T Nariai, Y Tanaka, T Maehara, N Miyakawa, S Sasaki, Y Momose-Sato, K Ohno

NEUROIMAGE 25(4) 1292-1301 2005年5月

もっとみる

書籍等出版物

前頭葉・頭頂葉の脳機能イメージング

片山容一, 富永悌二, 斉藤延人, editors. ビジュアル脳神経外科Anatomy & Surgical Approach 1 前頭葉・頭頂葉. 東京: メジカルビュー社 2010年
Positron Emission Tomography in Moyamoya Disease

Cho B-K, Tominaga T, editors. Moyamoya Disease Update. Tokyo: Springer 2010年
Whole-body tumor imaging: [O-11C]methyl-L-tyrosine/positron emission tomography. .

In: Hayat M, editor. Cancer Imaging: Instrument and Application. Amsterdam: Elsevier p. 175-9. 2008年
PET Multitracer Studyの脳神経疾患の臨床と研究への応用. In: 柳澤信夫, 篠原幸人, 岩田誠, 清水輝夫, 寺本明, editors. Annual Review 神経２００６

中外医学社 2006年
Testing for cerebral blood flow reserve for chronic ischemic diseases : comparison of Data obtained with Xe-CT/CBF Acetazolamide challenge test and positron emission tomography.

In:Tomonaga M,Tanaka A,Yonas H, ed. Quantiative cerebral blood flow measurements using stable xenon/CT: clinical application. Armonk, NY:Futura Pubishing Company, Inc., 1995年
キセノンCTとPET

にゅ-ろん社,キセノンCTによるClinical CBF measurement 1993年

所属学協会

共同研究・競争的資金等の研究課題

もやもや病の病態と治療法に関する研究

2100年
光学計測法の実験的臨床的応用による脳内神経回路網の研究

科学研究費補助金
神経受容体計測によるてんかん源性と防御機構の解明

科学研究費補助金
機能画像計測を用いた神経損傷とその再生に向けての実験的・臨床的研究

科学研究費補助金
悪性脳腫瘍の粒子線治療へのPETの応用

科学研究費補助金
高次脳機能局在計測の脳神経外科臨床への応用

科学研究費補助金
Clinical and experimental application of optical imaging for the investigation of cerebral neuronal circuit

Grant-in-Aid for Scientific Research
Evaluation of epileptogenecity and protection against it in patients with intractable epilepsy

Grant-in-Aid for Scientific Research
Clinical Experimental Study of neuronal damage and its regeneration with Functional Neuro imaging

Grant-in-Aid for Scientific Research
Application of PET imaging of malignant glioma for the development of novel treatment.

Grant-in-Aid for Scientific Research
Use of Functional Mapping in neurosurgical clinic

Grant-in-Aid for Scientific Research