東洋 (Hiroshi Azuma) - マイポータル - researchmap

基本情報

所属: 旧所属東京医科歯科大学生体材料工学研究所システム研究部門教授

学位: 薬学博士

J-GLOBAL ID: 200901034467951068
researchmap会員ID: 1000014440

研究キーワード

2

研究分野

1

ライフサイエンス / 薬理学 /

学歴

4

委員歴

3

1990年

日本脈管作動物質学会, 編集委員
1969年

日本薬理学会, 評議員
The Japanese Pharmacological Society, Councilor

受賞

4

2003年

BioFuture Research Encouragment Award (The First Prize)
1998年

平成10年度日本更年期医学会学術奨励賞
1998年

North American Menopause Society (NAMS) , The 1998 Young Inrestigator's Award
1996年

第２回Ciba Menopause Award

MISC

106

Inhibitory effect of activated protein C on cerebral vasospasm after subarchnoid hemorrhage in the rabbit.

Journal of Cardiovascular Pharmacology 39, 729-738 2002年
Different distribution of nitric oxide synthase and soluble guanylate cyclase activities in the detrusor and proximal urethra of the rabbit.

Journal of Urology 168, 2286-2290 2002年
Accumulated endogenous NOS inhibitors, decreased NOS activity and impaired cavernosal relaxation with ischemia.

Americal Journal of Physiology 282, R1730-R1738 2002年
Changed responsiveness of the detrusor in rabbits with alloxan induced hyperglycemia: Possible role of 5-hydroxytryptamine for diabetic bladder dysfunction.

Journal of Urology 168, 303-307 2002年
Localization and role of nitric oxide synthase and endogenous nitric oxide synthase inhibitors in the rabbbit lower urinary tract.

Journal of Urology 167, 2235-2240 2002年
Endogenous nitric oxide synthase inhibitors in endothelial cells, endothelin-1 within the vessel wall and intimal hyperplasia in perimenopausal human uterine arteries.

Journal of Cardiovascular Pharmacology 39, 192-200 2002年
Involvement of accumulated endogenous NOS inhibitors and decreased NOS activity in the impaired neurogenic relaxation of the rabbit proximal urethra with ischaemia

H Masuda, T Tsujii, T Okuno, K Kihara, M Goto, H Azuma

BRITISH JOURNAL OF PHARMACOLOGY 133(1) 97-106 2001年5月
Endothelin-1-endothelin receptor type A mediates closure of rat ductus arteriosus at birth.

Journal of Physiology (London) 537, 579-585 2001年
Localization and role of ET-1, ETA and ETB receptors in the human Fallopian tube.

Molecular Human Reproduction 7, 1057-1063 2001年
17 Beta-estradiol increases nitric oxide and prostaglandin I2 production by the cultured human uterine arteries only in the histologically normal specimens.

Journal of Cardiovascular Pharmacology 38, 240-249 2001年
Role of cetral muscarinic cholinergic pathway for relaxation of the proximal urethra during voiding phase.

Journal of Urology 165, 999-1003 2001年
Effective improvement of the cerebral vasospasm after subarachnoid hemorrhage with low dose nitroglycerine.

Jornal of Cardiovascular Pharmcology 35, 45-50 2000年
ATZ1993, an orally active and novel nonpeptide antagonist for endothelin receptors and inhibition of intimal hyperplasia after balloon denudation of the rabbit carotid artery

H Azuma, J Sato, H Masuda, M Goto, S Tamaoki, A Sugimoto, H Hamasaki, H Yamashita

JAPANESE JOURNAL OF PHARMACOLOGY 81(1) 21-28 1999年9月
Production of endothelin by canine prostatic epithelial cells and its stimulatory effects on their growth

K Ishizaka, H Azuma, O Matsubara, S Kitahara, H Oshima

JOURNAL OF ANDROLOGY 20(4) 529-536 1999年7月
Localization and effects of hepatocyte growth factor on smooth muscle cells during neointimal formation after balloon denudation

M Aoyagi, S Yamamoto, H Azuma, M Yamamoto, M Tamaki, Y Niimi, K Hirakawa, K Yamamoto

HISTOCHEMISTRY AND CELL BIOLOGY 111(6) 419-428 1999年6月
Gestational changes in endothelin-1-induced myometrial contractions and receptors in the rat

Molecular Human Reproduction 5 270-276 1999年
Accelerated intimal hyperplasia and increased endogenous inhibitors for NO synthesis in rabbits with alloxan-induced hyperglycaemia

H Masuda, M Goto, S Tamaoki, H Azuma

BRITISH JOURNAL OF PHARMACOLOGY 126(1) 211-218 1999年1月
Endogenous asymmetrical dimethylarginine and hypertension associated with puromycin nephrosis in the rat

J Sato, H Masuda, S Tamaoki, H Hamasaki, K Ishizaka, O Matsubara, H Azuma

BRITISH JOURNAL OF PHARMACOLOGY 125(3) 469-476 1998年10月
Differences between proximal and distal portions of the male rabbit posterior urethra in the physiological role of muscarinic cholinergic receptors

K Nagahama, T Tsujii, T Morita, H Azuma, H Oshima

BRITISH JOURNAL OF PHARMACOLOGY 124(6) 1175-1180 1998年7月
Immunolocalization of matrix metalloproteinases in rabbit carotid arteries after balloon denudation

M Aoyagi, M Yamamoto, H Azuma, G Nagashima, Y Niimi, M Tamaki, K Hirakawa, K Yamamoto

HISTOCHEMISTRY AND CELL BIOLOGY 109(2) 97-102 1998年2月

もっとみる

書籍等出版物

3

The aging ovary-the changes in the vascular system of the ovary in perimenopausal periods. In "The Modern Management of the Menopause".

The Parthenon Publishing Group, New York, London 1994年
"Sphincter : Normal Function-Changes in Diseases"Innervation of the Oddi's sphincter

CRC Press Inc. 1992年
Role of β-adrenergic receptors in human benign prostatic hyperplasia. In "α-adrenoceptors : Signal transduction, ionic channels and effector organs"

Excerpta Medica 1992年

所属学協会

9

Works(作品等)

15

共同研究・競争的資金等の研究課題

6

くも膜下出血後の心肺機能障害発現機構に関する研究

基礎科学研究 1998年
閉経後の血管病変発現機構に関する研究

基礎科学研究 1998年
動脈硬化の発症、進展、防御機構に関する研究

基礎科学研究 1998年
Investigation on the mechanism causing dysfunction of cardiopulmonary system following subarachnoid hemorrhage

Basic Science Research Program 1998年
Investigation on the mechanism causing hyperplasic vascular diseases after menopause.

Basic Science Research Program 1998年
Investigation of the mechanism of initiation, progression and prevention of atherosclerosis

Basic Science Research Program 1998年