山口登喜夫 (Tokio Yamaguchi) - マイポータル - researchmap

基本情報

所属: 東京医科歯科大学難治疾患研究所ゲノム応用医学研究部門ゲノム応用医学研究部門助教授

学位: 薬学修士
医学博士

J-GLOBAL ID: 200901000015252314
researchmap会員ID: 1000014684

研究キーワード

6

研究分野

4

MISC

46

Heme oxygenase inhibits human airway smooth muscle proliferation via a bilirubin-dependent modulation of ERK1/2 phosphorylation

C Taille, A Almolki, M Benhamed, C Zedda, J Megret, P Berger, G Leseche, E Fadel, T Yamaguchi, R Marthan …

JOURNAL OF BIOLOGICAL CHEMISTRY 278(29) 27160-27168 2003年7月
Azidothymidine causes functional and structural destruction of mitochondria, glutathione deficiency and HIV-1 promoter sensitization

T Yamaguchi, Katoh, I, S Kurata

EUROPEAN JOURNAL OF BIOCHEMISTRY 269(11) 2782-2788 2002年6月
Leydig cell-derived heme oxygenase-1 regulates apoptosis of premeiotic germ cells in response to stress.

J. Clin. Invest. 149(4), 457-467. 2002年
Psychological stress increases bilirubin metabolites in human urine.

Biochem. Biophys. Res. Commun. 293, 517-520. 2002年
Increased expression of heme oxygenase-1 and bilirubin accumulation in foam cells of rabbit atherosclerotic lesions

M Nakayama, K Takahashi, T Komaru, M Fukuchi, H Shioiri, K Sato, T Kitamuro, K Shirato, T Yamaguchi, M Suematsu …

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 21(8) 1373-1377 2001年8月
Carbon monoxide from heme catabolism protects against hepatobiliary dysfunction in endotoxin-treated rat liver

T Kyokane, S Norimizu, H Taniai, T Yamaguchi, S Takeoka, E Tsuchida, M Naito, Y Nimura, Y Ishimura, M Suematsu

GASTROENTEROLOGY 120(5) 1227-1240 2001年4月
Increased expression of heme oxygenase-1 and bilirubin accumulation in foam cells of rabbit atherosclerotic lesions.

Arterioscler. Thromb. Vasc. Biol. 21, 1373-1377. 2001年
Carbon monoxide from heme catabolism protects against heoatobiliary dysfunction in endotoxin-treated rat liver.

Gastroenterology 120, 1227-1240. 2001年
Increased bilirubins and their derivatives in cerebrospinal fluid in Alzheimer's disease

T Kimpara, A Takeda, T Yamaguchi, H Arai, N Okita, S Takase, H Sasaki, Y Itoyama

NEUROBIOLOGY OF AGING 21(4) 551-554 2000年7月
Formation of bilirubin-like compound by the ethylene-induced peroxidase isozymes in banana peel.

Plant Peroxidase Newsletter 14, 69-77. 2000年
Increased bilirubins and their derivatives in cerebrospinal fluid in Alzheimer's disease.

Newrobiology of Aging 21, 551-554. 2000年
Administration of bacterial lipopolysaccharide to rats-induces heine oxygenase-1 and formation of antioxidant bilirubin in the intestinal mucosa

K. Otani, S. Shimizu, K. Chijiiwa, T. Morisaki, T. Yamaguchi, K. Yamaguchi, S. Kuroki, M. Tanaka

Digestive Diseases and Sciences 45(12) 2313-2319 2000年
Formation of bilirubin-like compound by the ethylene-induced peroxidase isozymes in banana peel.

Plant Peroxidase Newsletter 14 69-77 2000年
Effects of alpha-tocopherol levels in extrusion pellets on in vivo lipid peroxidation levels and antioxidant activities in cultured Yellowtail Seriola quinqueradiata injected with the causative bacteria of fish jaundice

T Ito, H Murata, T Tsuda, T Yamada, K Yamauchi, M Ukawa, T Yamaguchi, T Yoshida, T Sakai

FISHERIES SCIENCE 65(5) 679-683 1999年10月
Induction of heme oxygenase-1 suppresses venular leukocyte adhesion elicited by oxidative stress role of bilirubin generated by the enzyme

S Hayashi, R Takamiya, T Yamaguchi, K Matsumoto, SJ Tojo, T Tamatani, M Kitajima, N Makino, Y Ishimura, M Suematsu

CIRCULATION RESEARCH 85(8) 663-671 1999年10月
carbon monoxide-mediated alterations in paracellular permeability and vesicular transport in acetaminophen-treated perfused rat liver.

Hepatology 30. 160-168. 1999年
Induction of heme oxygenase-1 suppresses venular leukocyte adhesion elicided by oxidative stress: Role of bilirubin generated by the enzyme

Circ. Res. 85, 663-671. 1999年
Carbon monoxide overproduced by heme oxygenase-1 causes a reduction of microvascular tone in perfused rat liver.

Am. J. Physiol 277(G1088-G1095) 1999年
Protective effects of heme oxygenase-1 against oxidant-induced injury in the cultured human tracheal epithelium.

Am. J. Resp. Cell. Mol. & Biol 21(3) 428-435 1999年
Carbon monoxide-mediotod alteration in paracellular permeabilty and esicle transport in acetaminophen-treated perfused rat liver.

Hepatology 30(1) 160-168 1999年

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所属学協会

5

共同研究・競争的資金等の研究課題

6