HIRAOKA Masayasu

J-GLOBAL         Last updated: Jul 22, 2010 at 00:00
HIRAOKA Masayasu
Ministry of Health, Labour and Welfare
Job title

Research Interests


Research Areas



Graduate School, Division of Medicine, Tokyo Medical and Dental University
Faculty of Medicine, Tokyo Medical and Dental University


Mechanism of increased amplitude and duration of the plateau with sudden shortening of diastolie intervals in rabbit ventricular cells
Circulation Research   60(1)    1987
Barium-induced automatic activity in isolated Ventricular myocytes from guinea-pig hearts.
Journal of Physiology   395    1988
Calcium-sensitive and insensitive transient outward current in rabbit ventricular myocytes.
Journal of Physiology   410    1989
Activation of ATP-sensitive outward K+current by nicorandil (2-Nicotinamidoetayl nitrate) in isolated ventricular myocytes
Journal of Pharmacology and Experimental Therapeutics   250    1989
Amantadine-induced afterpotentials and automaticity in guinea-pig Ventricular myocytes
Circulation Research   65    1989

Books etc

Opening of ATP-sensitive K+ channels during hypoxia protects against development of reperfusion arrhythmias. In "The Adapted Heart"
Raven Press   1994   
Electrophysiological view of antiarrhythmic drugs from a single myocardial cells. In "Recent Developments in the Management of Arrhythmias"
Royal Soc. Med. Press, London   1994   
Action of class III antiarrhythmic agents on cardiac muscle. In "Cardiac Pacing and Electrophysiology Today"
Simul, Tokyo   1994   
Regulation of cardiac delayed rectifier K+ channels and ATP-sensitive K+ channels by intracellular factors. In "Potassium Channels in Normal anf Pathological Conditions"
Leuven University Press, Leuven, Belgium   1995   
Action of K+ channel openers on the ATP-sensitive K+ channels of the heart and potential therapeutic impications. In "Recent Progress in Electrophamacology of the Heart".
CRC Press, New York   1995   


Japanese Circulation Journal 55(Suppl. (]G0002[)) : 267-288
Japanese Circulation Journal 55(Suppl. (]G0002[)) : 262-265
Etiology and pathogenesis of life-threatening arrhythmias
1998 - 2000
Pathogenetic mechanisms life-threatening arrhythmias caused by mutations of cardiac potassium channesl
1999 - 2001
Electrophysiological mechanisms of idiopathic ventricular fibrillation.

Research Grants & Projects

Cardiac electrophysiology
Electro cardiology
Genetic Aspects of arrhythmic disorders
Project Year: 1998   
Genetic Aspects of arrhythmic disorders
Project Year: 1998