1988年
Selective preparation of 1-substituted 2,2-difluoroethenyl phosphates or 1-hydroxyalkanephosphonates through the reaction of chlorodifluoromethyl ketones with dialkyl or diaryl phosphites
Journal of Fluorine Chemistry
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- 巻
- 38
- 号
- 2
- 開始ページ
- 263
- 終了ページ
- 277
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/S0022-1139(00)83035-3
Various chlorodifluoromethyl ketones react readily with dialkyl or diaryl phosphites in the presence of triethylamine at the reflux temperature of tetrahydrofuran to give the corresponding dialkyl or diaryl 1-substituted-2,2-difluoroethenyl phosphates in good yields, whereas the similar reaction conducted at lower temperature (0-20 °C) affords 1-(chlorodifluoromethyl)-1-hydroxyalkanephosphonates almost exclusively. The latter compounds are converted to the former enol phosphates by the treatment with triethylamine or sodium methoxide in refluxing tetrahydrofuran. © 1988.
- ID情報
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- DOI : 10.1016/S0022-1139(00)83035-3
- ISSN : 0022-1139
- SCOPUS ID : 34648830791