SEKINE MITSUO - My portal - researchmap

Profile Information

Degree: Doctor of Science
Master of Science

J-GLOBAL ID: 200901075751312308
researchmap Member ID: 1000015991

Research History

9

1999

-:東京工業大学教授
1999

-:
1989

-:東京工業大学助教授
1989

-:
1988

-:東京工業大学講師
1988

-:
1977

-:東京工業大学助手
1977

-:
Professor, Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology, Department of Life Science, Graduate School of Bioscience and Biotechnology Life Science

Education

3

Committee Memberships

4

2001 - 2001

Financial Committee Member, International Society for Nucleosides, Nucleotides and Nucleic Acids
2001 - 2001

2002 、Membership Committee Member, International Society for Nucleosides, Nucleotides and Nucleic Acids
1994 - 1995

有機合成化学協会誌関東支部常任幹事, 有機合成化学会協会
1991 - 1992

欧文誌編集委員, 日本化学会

Awards

2

1982

日本化学会進歩賞
1978

手島記念研究奨励賞

Misc.

282

1,1-Dihydroperoxycyclododecaneas a new, crystalline non-hygroscopic oxidizer for the chemical synthesis of oligodeoxyribonucleotides

Hisao Saneyoshi, Kenichi Miyata, Kohji Seio, Mitsuo Sekine

TETRAHEDRON LETTERS, 47(50) 8945-8947, Dec, 2006
1,1-Dihydroperoxycyclododecaneas a new, crystalline non-hygroscopic oxidizer for the chemical synthesis of oligodeoxyribonucleotides

Hisao Saneyoshi, Kenichi Miyata, Kohji Seio, Mitsuo Sekine

TETRAHEDRON LETTERS, 47(50) 8945-8947, Dec, 2006
Synthesis of 2 '-O-methyl-RNAs incorporating a 3-deazaguanine, and UV melting and computational studies on its hybridization properties

Kohji Seio, Takeshi Sasami, Ryuya Tawarada, Mitsuo Sekine

NUCLEIC ACIDS RESEARCH, 34(16) 4324-4334, Sep, 2006
Synthesis of 2 '-O-methyl-RNAs incorporating a 3-deazaguanine, and UV melting and computational studies on its hybridization properties

Kohji Seio, Takeshi Sasami, Ryuya Tawarada, Mitsuo Sekine

NUCLEIC ACIDS RESEARCH, 34(16) 4324-4334, Sep, 2006
Conformational studies of 4-N-carbamoyldeoxycytidine derivatives and synthesis and hybridization properties of oligodeoxyribonucleotides incorporating these modified bases

Kenichi Miyata, Akio Kobori, Ryuji Tamamushi, Akihiro Ohkubo, Haruhiko Taguchi, Kohji Seio, Mitsuo Sekine

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2006(16) 3626-3637, Aug, 2006
Conformational studies of 4-N-carbamoyldeoxycytidine derivatives and synthesis and hybridization properties of oligodeoxyribonucleotides incorporating these modified bases

Kenichi Miyata, Akio Kobori, Ryuji Tamamushi, Akihiro Ohkubo, Haruhiko Taguchi, Kohji Seio, Mitsuo Sekine

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2006(16) 3626-3637, Aug, 2006
Improved synthesis of oligonucleotides containing 2-thiouridine derivatives by use of diluted iodine solution

Okamoto, I, K Seio, M Sekine

TETRAHEDRON LETTERS, 47(4) 583-585, Jan, 2006
Triplex Forming Ability of Oligonucleotides Containing 2'-O-Methyl-2-thiouridine or 2-Thiothymidine.

Okamoto K, Seio M. Sekine

Chem. Lett., 35 136-137, 2006
Haruhiko Taguchi, Akihiro Ohkubo, Kohji Seio, Hideaki Kakeya, Hiroyuki Osada, Takuma Sasaki, and Mitsuo Sekine

関根光雄

25 647-654, 2006
Use of 1,4-Anhydroerythritol Structures as a Key Skeleton of New Hydroxyl Protecting Groups Removable by Self-cyclization under Oxidative Conditions

Eri Utagawa, Kohji Seio, Mitsuo Sekine

J. Org. Chem., 71(20) 7668-7677, 2006
Synthesis of Fluorescent Cyclic Cytosine Nucleosides and Their Fluorescent Properties pon Incorporation into Oligonucleotides

Masahiro Mizuta, Ken-ichi Miyata Kohji Seio Tomofumi, Santa, Mitsuo Sekine

Nucleic Acids Res. Symposium Ser., 50 19-20, 2006
Synthesis of Deoxycytidine Derivative and Their Use for the Selective Photo Crosslinking with 5-Methylcytosine

Haruhiko Taguchi, Akihiro Ohkubo, Kohji Seio, Mitsuo Sekine

Nucleic Acids Res. Symposium Ser., 50 57-58, 2006
Synthesis and Properties of Artificial Base Pairs by Use of Halogen Bonds

Ryuta Tawarada, Kohji Seio, Mitsuo Sekine

Nucleic Acids Res. Symposium Ser., 50 121-122, 2006
Synthesis and Properties of DNA Oligomers Containing 2'-Deoxycytidine-N-Oxide

Hirosuke Tsunoda Akihiro Ohkubo, Haruhiko Taguchi, Kohji Seio, Mitsuo Sekine

Nucleic Acids Res. Symposium Ser., 50 189-190, 2006
RNA医薬の化学修飾

関根光雄

遺伝子医学Mook, 4 138-142, 2006
RNAケミストリー

大木忠明, 矢野純一, 実吉尚郎, 清尾康志, 関根光雄

蛋白質・核酸・酵素, 51 1000-1006, 2006
DNA Synthesis without Base Protection Using the Phosphoramidite Approach

Akihiro Ohkubo, Kohji Seio, Mitsuo Sekine

Current Protocol in Nucleic Acid Chemistry, 1(3.15) 1-20, 2006
Improved synthesis of oligonucleotides containing 2-thiouridine derivatives by use of diluted iodine solution

Okamoto, I, K Seio, M Sekine

TETRAHEDRON LETTERS, 47(4) 583-585, Jan, 2006
Triplex Forming Ability of Oligonucleotides Containing 2'-O-Methyl-2-thiouridine or 2-Thiothymidine.

Okamoto K, Seio M. Sekine

Chem. Lett., 35 136-137, 2006
Synthesis and biological properties of new phosmidosine analogs having an N-acylsulfamate linkage

Haruhiko Taguchi, Akihiro Ohkubo, Mitsuo Sekine, Kohji Seio, Hideaki Kakeya, Hiroyuki Osada, Takuma Sasaki

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 25(4-6) 647-654, 2006

More

Books and Other Publications

13

RNAの基礎知識、RNAi法とアンチセンス法

講談社サイエンティフィック, 2005
ＤＮＡの化学合成、”生物薬科学実験講座ー核酸”

日本化学会編, 2005
遺伝子分野で発揮される化学の力

化学, 2005
Frontiers in Organic Chemistry, Creation of Conformationally Rigid Bent and Linear Nucleic Acids by 3-Dimentional Fixation of Conformation of Mono- and Di-nucleotide Building Blocks

Bentham Science Publishers LTD., 2005
RNAi法とアンチセンス法

講談社サイエンティフィック, 2005
Frontiers in Organic Chemistry, Creation of Conformationally Rigid Bent and Linear Nucleic Acids by 3-Dimentional Fixation of Conformation of Mono- and Di-nucleotide Building Blocks

Bentham Science Publishers LTD., 2005
DNA Synthesis without Base Protection

Current Protocol in Nucleic Acid Chemistry, 2004
DNA Synthesis without Base Protection

Current Protocol in Nucleic Acid Chemistry, 2004
遺伝子、”化学ってそういうこと！ー夢広がる分子の世界ー”

化学同人, 2003
ゲノムケミストリー

講談社サイエンティフィック, 2003
ゲノムケミストリーを可能にする新技術、”ゲノムケミストリー”

講談社サイエンティフィック, 2003
N-Glycosylation

Glycoscience - Chemistry and Chemical biology, 2001
N-Glycosylation

Glycoscience - Chemistry and Chemical biology, 2001

Professional Memberships

15

Research Projects

10