Mikio Nakazawa - My portal - researchmap

Profile Information

Affiliation: Faculty of Medicine, School of Health Sciences, Department of Medical Technology, Niigata University

Degree: (BLANK)(Niigata University)

J-GLOBAL ID: 200901034731534772
researchmap Member ID: 1000018335

Research Interests

2

Research Areas

2

Research History

7

1990 - 2000

Faculty of Medicine, Niigata University
2000

- 新潟大学医学部教授
2000

- Professor, Faculty of Medicine, Niigata University
1986 - 1990

Faculty of Medicine, Niigata University
1981 - 1986

Faculty of Medicine, Niigata University
1975 - 1981

Faculty of Medicine, Niigata University
1972 - 1981

興和(株)東京研究所研究員

Education

2

Misc.

73

A novel scheme of dystrophin disruption for the progression of advanced heart failure

T Kawada, F Masui, A Tezuka, T Ebisawa, H Kumagai, M Nakazawa, T Toyo-oka

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 1751(1) 73-81, Aug, 2005
A novel paradigm for therapeutic basis of advanced heart failure - assessment by gene therapy

T Kawada, F Masui, H Kumagai, M Koshimizu, M Nakazawa, T Toyo-oka

PHARMACOLOGY & THERAPEUTICS, 107(1) 31-43, Jul, 2005
Effect of hydrodynamics-based gene delivery of plasmid DNA encoding interleukin-1 receptor antagonist-Ig for treatment of rat autoimmune myocarditis - Possible mechanism for lymphocytes and noncardiac cells

H Liu, H Hanawa, T Yoshida, R Elnaggar, M Hayashi, R Watanabe, K Toba, K Yoshida, H Chang, Y Okura, K Kato, M Kodama, H Maruyama, J Miyazaki, M Nakazawa, Y Aizawa

CIRCULATION, 111(13) 1593-1600, Apr, 2005
Translocation and cleavage of myocardial dystrophin as a common pathway to advanced heart failure: A scheme for the progression of cardiac dysfunction

T Toyo-Oka, T Kawada, J Nakata, H Xie, M Urabe, F Masui, T Ebisawa, A Tezuka, K Iwasawa, T Nakajima, Y Uehara, H Kumagai, S Kostin, J Schaper, M Nakazawa, K Ozawa

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 101(19) 7381-7385, May, 2004
Effects of pranidipine, a novel calcium channel antagonist, on the progression of left ventricular dysfunction and remodeling in rats with heart failure

MII Wahed, K Watanabe, ML Ma, M Nakazawa, T Takahashi, G Hasegawa, M Naito, T Yamamoto, M Kodama, Y Aizawa

PHARMACOLOGY, 72(1) 26-32, 2004
Morphological and physiological restorations of hereditary form of dilated cardiomyopathy by somatic gene therapy

T Kawada, A Sakamoto, M Nakazawa, M Urabe, F Masuda, C Hemmi, Y Wang, WS Shin, Y Nakatsuru, H Sato, K Ozawa, T Toyo-oka

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 284(2) 431-435, Jun, 2001
A novel 5-HT2 antagonist, sarpogrelate hydrochloride, shows inhibitory effects on both contraction and relaxation mediated by 5-HT receptor subtypes in porcine coronary arteries

HB Gong, T Nakamura, K Hattori, T Ohnuki, M Rashid, M Nakazawa, K Watanabe, T Nagatomo

PHARMACOLOGY, 61(4) 263-268, 2000
Acute effects of endothelin-1 and TAK-004(ET_A and ET_B receptro antagonist)in rat with dilated cardiomyopathy.

J. Cardiovasc. Pharmacol., 36(Suppl 2) S49-S54, 2000
Dystrophin distruption might be related to myocardial cell apoptosis caused by isoproterenol.

J. Cardiovasc. Pharmacol., 36(Suppl 2) S25-S29, 2000
Carvedilol enhances atrial and brain natriuretic peptide mRNA expression and release in rat heart.

J. Cardiovasc. Pharmacol., 36(Suppl 2) S19-S23, 2000
Effects of three different Ca2+ pump ATPase inhibitors on evoked contractions in rabbit aorta and activities of Ca2+ pump ATPase in porcine aorta.

Gen. Pharmacol, 34(3) 211-220, 2000
Low dose carvedilol inhibits progression of heart failure in rats with dilated cardiomyoapthy

Br. J. Pharmacol., 130(7) 1489-1495, 2000
Inhibitory effects of a newly synthesized 5-HT2 receptor antagonist, AT-1015(N-[2-]4-(5H-dibenzo[a,d]cyclohepten-5-ylidene9piperidino]-ethyl]-1-formyl-4-piperidineca rboximede monohydrochloride monohydrate), on contraction and relaxation of pig coronar・・・

Bio. Pharm. Bull, 23(9) 1105-1107, 2000
Strain- and age-dependent loss of sarcoglycan complex in cardiomyopathic hamster hearts and its re-expression by delta-sarcoglycan gene transfer in vivo

T Kawada, Y Nakatsuru, A Sakamoto, T Koizumi, WS Shin, Y Okai-Matsuo, J Suzuki, Y Uehara, M Nakazawa, H Sato, T Ishikawa, T Toyo-oka

FEBS LETTERS, 458(3) 405-408, Sep, 1999
Effects of log-term treatment woth carvedilol in rats with dilated cardiomyopathy after myocarditis.

J Cardiovasc Pharmacol, 34(Suppl4) S77-80, 1999
Precise identification of gene products in hearts after in vivo gene transfection, using sendai virus-coated proteoliposomes.

Biochem. Biophys. Res. Commun., 259(2) 408-413, 1999
Increasing vasoconstrictor response to ergonovine with oxidative injury in canine coronary artery

T Matsubara, M Nakazawa, Y Yoshida, S Imai, K Suzuki, T Hori, T Konno, K Higuchi, Y Tamura, M Yamazoe, T Izumi, Y Aizawa

CORONARY ARTERY DISEASE, 8(1) 1-7, Jan, 1997
Expression of inducible nitric oxide synthase in rat experimental autoimmune myocarditis with special reference to changes in cardiac hemodynamics

S Hirono, MO Islam, M Nakazawa, Y Yoshida, M Kodama, A Shibata, T Izumi, S Imai

CIRCULATION RESEARCH, 80(1) 11-20, Jan, 1997
Ethanol ingestion on allylamine-induced experimental subendocardial fibrosis.

Alcohol, 12(3) 233, 1995
Contribution of cyclic GMP generation to the relaxation by nipradilol in the rabbit aorta.

Gen. Pharmacol., 26(1) 85-91, 1995

More

Books and Other Publications

6

In vivo gene supplementation for the therapy of cardiomyopathy.

Heart Failura, 2000
Oxygen free radicals enhance ergonovine-induced canine coronary vasoconstriction.

Progress in Cardiology, The ishemic heart, 1998
Effects of angiotensin converting exzyme inhibitors on acute heart failure induced in the anesthetized dog with microsphere injection.

Mechanisms of heart failure Kluwer Academic Publishers, 1995
ATP pyrophosphohydrolase : a new pathway of extracellular adenosine formation.

Role of adenosine and adenine nucleotides in biological system. Elsevier, 1991
Role of ecto-5'-nucleotidase on hypoxia-induced adenosine formation in the perfused guinea pig heart.

Regulation of coronary blood flow. Springer-Verlag, 1991
5'-nucleotidase inhibitors and the myocardial rective hyperemia and adenosine content.

Topics and Perspectives in Adenosine Research Springer-Verlag, 1987

Professional Memberships

5

Works

6

Research Projects

8