ISHIBASHI Takaharu

J-GLOBAL         Last updated: Dec 8, 2019 at 04:17
 
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Name
ISHIBASHI Takaharu
Affiliation
Kanazawa Medical University
Section
School of Medicine
Job title
Professor
Degree
MD., Ph.D.

Research Interests

 
 

Academic & Professional Experience

 
Apr 1986
 - 
Sep 1986
Research Assistant, Asahikawa Medical College
 
Jan 1986
 - 
Dec 1997
Research Assistant, Niigata University School of Medicine
 
Jan 1998
 - 
Mar 2007
Associate Professor, Kanazawa Medical University
 
Sep 1993
 - 
Nov 1995
stipendiary researcher, Alexander von Humboldt Foundation
 

Education

 
 
 - 
1986
Division of Medicine, Graduate School, Asahikawa Medical College
 
 
 - 
1982
Faculty of Medicine, Asahikawa Medical College
 

Awards & Honors

 
2001
N0x contamination in laboratory ware and effect of countermeasures
 

Published Papers

 
Effects of cyanamide, an aldehyde dehydrogenase type2 inhibitor, on glyceryl trinitrate- and isosorbide dinitrate-induced vasodilation in rabbit excised aorta and in anesthetized whole animal.
T.Ishibashi, M.Nomura-Nakamoto, F.Abe, T.Masuoka, N.Imaizumi, J.Yoshida, Tomie Kawada, M.Nishio
Biological & pharmaceutical bulletin   36:556-563    Apr 2013
Role of plasma S-nitrosothiols in regulation of blood pressure in anesthetized rabbits with special references to hypotensive effects of acetylcholine and nitrovasodilators
T.Ishibashi, T.Miwa, N.Nishizawa, I.Shinkawa, J.Yoshida, T.Kawada, M.Nishio
Biological & pharmaceutical bulletin   34:1307-1313    Aug 2011
Differrent disappearance rates of plasma nitrite (NO2-) contribute to apparent steady-state arterio-venous differences in anesthetized animals
T.Ishibashi, N.Nishizawa, M.Nakamoto, F.Abe, H.Liu, J.Yoshida, T.Kawada, M.Nishio
Biological & pharmaceutical bulletin   34:528-537    Apr 2011
Effects of chronic cigarette smoking on endothelial function in young men
(K.Ozaki), T.Hori, T.Ishibashi, M.Nishio, Y.Aizawa
Journal of cardiology   56:307-313    Jul 2010
Amlodipine, a Ca2+ channel blocker, suppresses phosphorylation of epidermal growth factor receptor in human epidermoid carcinoma A431 cells
J.Yoshida, T.Ishibashi, M.Yang, M.Nishio
Life sciences.   86:124-132    Dec 2009

Misc

 
T.Ishibashi, N.Nishizawa, M.Nakamoto, F.Abe, H.Liu, J.Yoshida, T.Kawada, M.Nishio
Biol.Pharm.Bull.   34 528-537   2011
カルシウム拮抗薬の多様な作用-その細胞増殖抑制作用を中心に-
30 420-426   2005
Significance of NOx concentration in red blood cells
13 135-136   2004
冠動脈粥状硬化症に伴う内皮機能障害と炎症
4(増刊) 54   2002
若年男性喫煙者における末梢血管内皮機能障害と一酸化窒素産生能との関連
38 21-28   2001
Growth-inhibitory effect of a streptococcal antitumor glycoprotein on human epidermoid carcinoma A431 cells: Involvement of dephosphorylation of epidermal growth factor receptor
61 6151-6157   2001
Respiratory alkalosis dose not alter NOx concentration in human plasma and erythrocytes
   2001
Growth inhibitory effect of a streptococcal antitumor glycoprotein on human epidermoid carcinoma A431 cells: Involvement of dephosphorylation of epidermal growth factor receptor
   2001
若年男性喫煙者における末梢血管内皮機能障害と一酸化窒素産性能との関連
   2001
Respiratory alkalosis does not alter NOx concentrations in human plasma and erythrocytes
281 H2757-H2761   2001
冠攣縮性狭心症における冠動脈血管緊張度と冠循環中NO動態の関連についての検討
   1998
「組織血流測定-カラードマイクロスフェアーによる-」
   1998
K+チャンネル開口薬(共)
   1998
Charakterisierung rekombinanter iNOS in COS-Zellen
   1996
誘導型一酸化窒素合成酵素(inducible nitric oxide synthase:iNOS)の活性調節(若手研究者による最新海外情報)
   1996
エンフルラン麻酔下イヌの全身循環、腎臓、脳および冠循環に対するニトロプルシド(MR7S1)およびニトログリセンの作用
   1995
新規カルシウム拮抗薬 Lacidipineの心血行動態に対する作用
   1994
迷走神経からのアセチルコリンの遊離
   1993
ニコランジルとKRN2391の血管拡張作用の機序:ピリジン核を持つKチャンネルオープナーの構造と活性
   1993
Bopindolol : preclinical study and clinical correlations
   1992
心筋に対するNO-forming vasodilatorsの作用:ミオグロビンとcGMP含量との関係
   1992
NMRスペクトル分析の基礎技術
   1992
Hypotensive mechanisms of carvedilol
   1991
NicorandilおよびSG209の活性と構造の関係
   1991
潅流心臓におけるNa+/H+交換系の役割:NMRを用いた検討
   1990
Intracellular sodium,potassium and high energy phosphate levels in the myocardium during ischemia : Studies with 23Na- 39K- and 31P-NMR.
   1989
心筋の収縮弛緩機構
   1989
NO産生性血管拡張薬の最近の知見
   1989
Changes in myocardial energy metabolism and Na+ permeability produced by a long ischemia as studied by 31P- and 23Na-NMR
   1988
循環器治療薬-最新の知見:降圧薬
   1988
31P-NMRと 23Na-NMRを用いた長時間虚血の検討
   1988
低酸素心筋とアデノシン 「虚血心筋」
   1987
トロンボキサンA2の生物活性と薬用作用
   1987
虚血時の心筋代謝:NMRによる検討
   1987
Changes in coronary flow and effluent adenosine during hypoxia in the isolated rat heart, with special reference to myocardial oxygen uptake
   1986
中枢性血圧降下薬
   1985
低酸素心筋とアデノシン
   1984
心血管系への作用
   1984
強心薬
   1984
心筋梗塞の前駆症状としての狭心症
   1983
当院における過去3年間の時間外心疾患診療の実態
   1982
Zur Biochemie von Nifedipine
   1981
フェニトイン
   1981
T.Ishibashi, N.Nishizawa, M.Nakamoto, F.Abe, H.Liu, J.Yoshida, T.Kawada, M.Nishio
Biol.Pharm.Bull.   34 528-537   2011
Charakterisierung rekombinanter iNOS in COS-Zellen
ISHIBASHI Takaharu
Zeitschrift fuer Kardiologie (German Journal of Cardiology).      1996
Bopindolol : preclinical study and clinical correlations
ISHIBASHI Takaharu
Progress in Hyperension(VSP press. Holland)      1992
Hypotensive mechanisms of carvedilol
ISHIBASHI Takaharu
J.Pharmacobio-Dyn.      1991
Intracellular sodium,potassium and high energy phosphate levels in the myocardium during ischemia : Studies with 23Na- 39K- and 31P-NMR.
ISHIBASHI Takaharu
J.Mol.Cell.Cardiol.      1989
Changes in myocardial energy metabolism and Na+ permeability produced by a long ischemia as studied by 31P- and 23Na-NMR
ISHIBASHI Takaharu
J.Mol.Cell.Cardiol.      1988
Changes in coronary flow and effluent adenosine during hypoxia in the isolated rat heart, with special reference to myocardial oxygen uptake
ISHIBASHI Takaharu
Pfluegers Archiv      1986
Zur Biochemie von Nifedipine
ISHIBASHI Takaharu
Schwerpunkt-Medizin      1981

Books etc

 
第20章 心臓血管系: 心臓
Mar 2010   
第20章 心臓血管系: 心臓
Jan 2007   
第15章 心臓血管系: 心臓
Jan 2007   
第20章 心臓血管系:心臓
Dec 2012   
第20章 心臓血管系:心臓
2004   
第15章 心臓血管系:心臓
2004   
第2章 末梢神経疾患に対する薬物
Mar 2018   
A New Aspect of Cholinergic Transmission in the Central Nervous System
Ikunobu Muramatsu, Takayoshi Masuoka, Junsuke Uwada, Hatsumi Yoshiki, Takashi Yazama, Kung-Shing Lee, Kiyonao Sada, Matomo Nishio, Takaharu Ishibashi, Takanobu Taniguchi.
Apr 2018   

Conference Activities & Talks

 
Decrease in plasma NOx concentration during depressor responses to arginine infusion in patients with or without diabetes mellitus
*K.Maejima, *M.Himeno, T.Ishibashi, *S.Nakano, *K.Uchida, J.Yoshida, M.Nishio
2000   
Dephosphorylation of epidermal growth factor receptor by an antitumor streptococcal glycoprotein
J.Yoshida, T.Ishibashi, M.Nishio
2000   
Fluvastatinが培養血管内皮細胞におけるNOおよびET-1産生へおよぼす作用
2000   
冠動脈硬化症患者における冠循環血中NOと脂質過酸化レベルについて
2000   
血漿NOx基礎値と糖尿病合併症との関連について
2000   

Works

 
NOおよびNO関連血管拡張薬の作用桟序
1999
Vaso relaxant mechanism of nitric oxide and related vasodilators
1999
NOおよびNO関連物質の体内動態
1998
Kinetics of NO and NO-related compounds
1998
ニトロソチオールの作用と体内動態

Research Grants & Projects

 
NOおよびNO関連血管拡張薬の作用機序
Project Year: 1996   
NOおよびNO関連物質の体内動態
Project Year: 1998   
Vasorelaxant mechanism of nitric oxide and related vasodilators
Project Year: 1996   
Kinetics of NO and NO - related compounds
Project Year: 1998   
ニトロソチオールの作用と体内動態