2016年7月
Spatio-temporal expression of Sox genes in murine palatogenesis
GENE EXPRESSION PATTERNS
- 巻
- 21
- 号
- 2
- 開始ページ
- 111
- 終了ページ
- 118
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.gep.2016.05.002
- 出版者・発行元
- ELSEVIER SCIENCE BV
Members of the Sox gene family play critical roles in many biological processes including organogenesis. We carried out comparative in situ hybridisation analysis of seventeen Sox genes (Sox1-14, 17, 18 and 21) during murine palatogenesis from initiation to fusion of the palatal shelves above the dorsal side of the tongue. At palatal shelf initiation (E12.5), the localized expression of six Sox genes (Sox2, 5, 6, 9,12 and 13) was observed in the shelves, whereas Sox4 and Sox11 showed ubiquitious expression. During the down growth of palatal shelves (E13.5), Sox4, Sox5, and Sox9 exhibited restricted expression to the interior side of the palatal shelves facing the tongue. Following elevation of the palatal shelves (E14.5), Sox2, Sox11 and Sox21 expression was present in the midline epithelial seam. We thus identify dynamic spatio-temporal expression of Sox gene family during the process of palatogenesis. (C) 2016 Elsevier B.V. All rights reserved.
- リンク情報
- ID情報
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- DOI : 10.1016/j.gep.2016.05.002
- ISSN : 1567-133X
- eISSN : 1872-7298
- PubMed ID : 27241892
- Web of Science ID : WOS:000385324500007