横山茂 (Shigeru Yokoyama) - マイポータル

基本情報

所属: 金沢大学子どものこころの発達研究センター教授 (センター長)

学位: 博士(医学)(金沢大学)

研究者番号: 00210633
J-GLOBAL ID: 200901034589517954
researchmap会員ID: 1000019820

研究キーワード

研究分野

学歴

1985年4月 - 1988年3月

金沢大学, 医学研究科, 病理系免疫生物学
1979年4月 - 1985年3月

金沢大学, 医学部, 医学科

委員歴

1999年 - 現在

-:日本神経化学会評議委員
1999年

-: Japanese Society of Neurochemistry
1999年

日本神経化学会, 評議委員、シンポジウムプログラム委員

受賞

2001年

平成13年度本陣奨励金
1994年

興和生命科学振興財団研究奨励金
1994年

Grant-in aid from Kowa Life Science Foundation
1990年

老人医療基金研究奨励金
1990年

公益信託松原三郎記念精神医学育成基金
1990年

Grant-in-aid from Foundation for Geriatric Medicine
1990年

Grant-in-aid from Saburo Matsubara Memorial Psychiatry Foundation
1988年

日本心臓財団研究助成金
1988年

Grant-in-aid from Japan Heart Foundation

論文

145

R150S mutation in the human oxytocin receptor: Gain-of-function effects and implication in autism spectrum disorder

Xiaoxi Liu, Stanislav Cherepanov, Mehdi Abouzari, Amila Zuko, Shu Yang, Jamasb Sayadi, Xiaoyuan Jia, Chikashi Terao, Tsukasa Sasaki, Shigeru Yokoyama

Peptides 182 171301-171301 2024年12月査読有り
Functional identification of soluble uric acid as an endogenous inhibitor of CD38.

Shijie Wen, Hiroshi Arakawa, Shigeru Yokoyama, Yoshiyuki Shirasaka, Haruhiro Higashida, Ikumi Tamai

eLife 13 2024年11月11日
Association of genetic variants with autism spectrum disorder in Japanese children revealed by targeted sequencing.

Yuka Shiota, Tomoaki Nishiyama, Shigeru Yokoyama, Yuko Yoshimura, Chiaki Hasegawa, Sanae Tanaka, Sumie Iwasaki, Mitsuru Kikuchi

Frontiers in genetics 15 1352480-1352480 2024年
Association between copy number variations in parkin (PRKN) and schizophrenia and autism spectrum disorder: A case-control study.

Tzuyao Lo, Itaru Kushima, Hiroki Kimura, Branko Aleksic, Takashi Okada, Hidekazu Kato, Toshiya Inada, Yoshihiro Nawa, Youta Torii, Maeri Yamamoto …

Neuropsychopharmacology reports 2023年11月1日
Oral Supplementation with Maca Improves Social Recognition Deficits in the Valproic Acid Animal Model of Autism Spectrum Disorder.

Pinyue Fu, Shuxin Luo, Zhongyu Liu, Kazumi Furuhara, Takahiro Tsuji, Haruhiro Higashida, Shigeru Yokoyama, Jing Zhong, Chiharu Tsuji

Brain sciences 13(2) 2023年2月13日
Two oxytocin analogs, N-(p-fluorobenzyl) glycine and N-(3-hydroxypropyl) glycine, induce uterine contractions ex vivo in ways that differ from that of oxytocin

Stanislav M. Cherepanov, David Desseauve, Teruko Yuhi, Takashi Iizuka, Takashi Hosono, Masanori Ono, Hiroshi Fujiwara, Shigeru Yokoyama, Satoshi Shuto, Haruhiro Higashida

PLOS ONE 18(2) e0281363 2023年2月9日査読有り
Genetic polymorphisms of bone marrow stromal cell antigen-1 (BST-1/CD157): implications for immune/inflammatory dysfunction in neuropsychiatric disorders.

Shigeru Yokoyama

Frontiers in immunology 14 1197265-1197265 2023年
Infant Stimulation Induced a Rapid Increase in Maternal Salivary Oxytocin.

Kana Minami, Teruko Yuhi, Haruhiro Higashida, Shigeru Yokoyama, Takahiro Tsuji, Chiharu Tsuji

Brain sciences 12(9) 2022年9月15日
Early-onset of social communication and locomotion activity in F2 pups of a valproic acid-induced mouse model of autism.

Chiharu Tsuji, Kazumi Furuhara, Ryuko Mizutani, Kana Minami, Pinyue Fu, Jing Zhong, Haruhiro Higashida, Shigeru Yokoyama, Takahiro Tsuji

Neuroscience letters 788 136827-136827 2022年8月6日
Oxytocin Dynamics in the Body and Brain Regulated by the Receptor for Advanced Glycation End-Products, CD38, CD157, and Nicotinamide Riboside

Haruhiro Higashida, Kazumi Furuhara, Olga Lopatina, Maria Gerasimenko, Osamu Hori, Tsuyoshi Hattori, Yasuhiko Hayashi, Stanislav M. Cherepanov, Anna A. Shabalova, Alla B. Salmina …

Frontiers in Neuroscience 16 2022年7月7日
Effect of CNTNAP2 polymorphism on receptive language in children with autism Spectrum disorder without language developmental delay.

Yuka Shiota, Tetsu Hirosawa, Yuko Yoshimura, Sanae Tanaka, Chiaki Hasegawa, Sumie Iwasaki, Masuhiko Sano, Kyung-Min An, Shigeru Yokoyama, Mitsuru Kikuchi

Neuropsychopharmacology reports 2022年6月22日
Alterations in brain networks in children with sub-threshold autism spectrum disorder: A magnetoencephalography study.

Yuka Shiota, Daiki Soma, Tetsu Hirosawa, Yuko Yoshimura, Sanae Tanaka, Chiaki Hasegawa, Ken Yaoi, Sumie Iwasaki, Masafumi Kameya, Shigeru Yokoyama …

Frontiers in psychiatry 13 959763-959763 2022年
An improved sample extraction method reveals that plasma receptor for advanced glycation end-products (RAGE) modulates circulating free oxytocin in mice.

Stanislav M Cherepanov, Maria Gerasimenko, Teruko Yuhi, Anna Shabalova, Hong Zhu, Shigeru Yokoyama, Alla B Salmina, Shei-Ichi Munesue, Ai Harashima, Yasuhiko Yamamoto …

Peptides 146 170649-170649 2021年12月
Receptor for advanced glycation end-products (RAGE) plays a critical role in retrieval behavior of mother mice at early postpartum.

Maria Gerasimenko, Olga Lopatina, Seiichi Munesue, Ai Harashima, Shigeru Yokoyama, Yasuhiko Yamamoto, Haruhiro Higashida

Physiology & behavior 235 113395-113395 2021年6月1日
Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism.

Stanislav M Cherepanov, Maria Gerasimenko, Teruko Yuhi, Kazumi Furuhara, Chiharu Tsuji, Shigeru Yokoyama, Keiichi I Nakayama, Masaaki Nishiyama, Haruhiro Higashida

BMC neuroscience 22(1) 32-32 2021年5月1日
A common variant of CNTNAP2 is associated with sub-threshold autistic traits and intellectual disability.

Yuka Shiota, Tetsu Hirosawa, Yuko Yoshimura, Sanae Tanaka, Chiaki Hasegawa, Sumie Iwasaki, Kyung-Min An, Daiki Soma, Masuhiko Sano, Shigeru Yokoyama …

PloS one 16(12) e0260548 2021年
Distinct physical condition and social behavior phenotypes of CD157 and CD38 knockout mice during aging.

Maria Gerasimenko, Olga Lopatina, Anna A Shabalova, Stanislav M Cherepanov, Alla B Salmina, Shigeru Yokoyama, Hisanori Goto, Hiroshi Okamoto, Yasuhiko Yamamoto, Katsuhiko Ishihara …

PloS one 15(12) e0244022 2020年12月
Nicotinamide riboside supplementation corrects deficits in oxytocin, sociability and anxiety of CD157 mutants in a mouse model of autism spectrum disorder.

Maria Gerasimenko, Stanislav M Cherepanov, Kazumi Furuhara, Olga Lopatina, Alla B Salmina, Anna A Shabalova, Chiharu Tsuji, Shigeru Yokoyama, Katsuhiko Ishihara, Charles Brenner …

Scientific reports 10(1) 10035-10035 2020年6月22日査読有り
Oxytocin and CD38 in the paraventricular nucleus play a critical role in paternal aggression in mice.

Anna A Shabalova, Mingkun Liang, Jing Zhong, Zhiqi Huang, Chiharu Tsuji, Natalia A Shnayder, Olga Lopatina, Alla B Salmina, Hiroshi Okamoto, Yasuhiko Yamamoto …

Hormones and behavior 120 104695-104695 2020年4月査読有り
A monoclonal antibody raised against a synthetic oxytocin peptide stains mouse hypothalamic neurones.

Yuji Kogami, Takahiro Tsuji, Chiharu Tsuji, Shigeru Yokoyama, Kazumi Furuhara, Olga Lopatina, Anna Shabalova, Alla B Salmina, Yumi Watanabe, Tsuyoshi Hattori …

Journal of neuroendocrinology 32(4) e12815 2020年4月査読有り