Kuroda Akio

J-GLOBAL         Last updated: Jan 8, 2019 at 14:25
Kuroda Akio
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Hiroshima University
Research funding number

Awards & Honors

Oct 1995
"Human frontier science program, Long-term fellowship award."

Published Papers

Ikeda, Atsushi; Satake, Shuhei; Mae, Tomoya; Ueda, Masafumi; Sugikawa, Kouta; Shigeto, Hajime; Funabashi, Hisakage; Kuroda, Akio
ACS MEDICINAL CHEMISTRY LETTERS   8(5) 555-559   May 2017   [Refereed]
Water-soluble cyclodextrin (CyD) complexed with porphyrin derivatives with different substituents in the meso-positions showed different photodynamic activities toward cancer cells under illumination at wavelengths over 600 nm, the most suitable w...
Hirota, Ryuichi; Abe, Kenji; Katsuura, Zen-ichiro; Noguchi, Reiji; Moribe, Shigeaki; Motomura, Kei; Ishida, Takenori; Alexandrov, Maxym; Funabashi, Hisakage; Ikeda, Takeshi; Kuroda, Akio
SCIENTIFIC REPORTS   7    Mar 2017   [Refereed]
There is a growing demand to develop biocontainment strategies that prevent unintended proliferation of genetically modified organisms in the open environment. We found that the hypophosphite (H3PO2, HPt) transporter HtxBCDE from Pseudomonas stutz...
Ikeda, Atsushi; Mae, Tomoya; Ueda, Masafumi; Sugikawa, Kouta; Shigeto, Hajime; Funabashi, Hisakage; Kuroda, Akio; Akiyama, Motofusa
CHEMICAL COMMUNICATIONS   53(20) 2966-2969   Mar 2017   [Refereed]
[60]Fullerene (C-60) derivatives were incorporated into liposomes using a fullerene exchange method involving the transfer of the fullerene from the cavity of two gamma-cyclodextrin molecules to a liposome. A lipid-membrane- incorporated C-60 deri...
Abe, Kenji; Kuroda, Akio; Takeshita, Ryo
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY   101(5) 2057-2066   Mar 2017   [Refereed]
Industrial glucose feedstock prepared by enzymatic digestion of starch typically contains significant amounts of disaccharides such as maltose and isomaltose and trisaccharides such as maltotriose and panose. Maltose and maltosaccharides can be ut...
Nishimura, Tomoki; Alexandrov, Maxym; Ishida, Takenori; Hirota, Ryuichi; Ikeda, Takeshi; Sekiguchi, Kiyoshi; Kuroda, Akio
ANNALS OF OCCUPATIONAL HYGIENE   60(9) 1104-1115   Nov 2016   [Refereed]
Considering the increasing use of various asbestos substitutes, asbestos risk management in many industries may require accurate techniques for detecting and distinguishing asbestos from non-asbestos fibers. Using fluorescently labeled asbestos-bi...
Abdelhamid, Mohamed A. A.; Ikeda, Takeshi; Motomura, Kei; Tanaka, Tatsuya; Ishida, Takenori; Hirota, Ryuichi; Kuroda, Akio
JOURNAL OF BIOSCIENCE AND BIOENGINEERING   122(5) 633-638   Nov 2016   [Refereed]
We recently reported that the spore coat protein, CotB1 (171 amino acids), from Bacillus cereus mediates silica biomineralization and that the polycationic C-terminal sequence of CotB1 (14 amino acids), designated CotB1p, serves as a silica-bindin...
Shigeto, Hajime; Nakatsuka, Keisuke; Ikeda, Takeshi; Hirota, Ryuichi; Kuroda, Akio; Funabashi, Hisakage
ANALYTICAL CHEMISTRY   88(16) 7894-7898   Aug 2016   [Refereed]
This letter discusses the feasibility of continuously monitoring specific mRNA expression responses in a living cell with a probe structured as a fluorescence resonance energy transfer (FRET)-based DNA nano-tweezer (DNA NT). The FRET-based DNA-NT,...
Kuroda, Akio; Alexandrov, Maxym; Nishimura, Tomoki; Ishida, Takenori
BIOTECHNOLOGY JOURNAL   11(6) 757-767   Jun 2016   [Refereed]
A large number of peptides with binding affinity to various inorganic materials have been identified and used as linkers, catalysts, and building blocks in nanotechnology and nanobiotechnology. However, there have been few applications of material...
Saiki, Asako; Ishida, Yasuaki; Segawa, Shuichi; Hirota, Ryuichi; Nakamura, Takeshi; Kuroda, Akio
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   80(5) 955-961   May 2016   [Refereed]
Inorganic polyphosphate (polyP) was previously identified as a probiotic-derived substance that enhances intestinal barrier function. PolyP-accumulating bacteria are expected to have beneficial effects on the human gastrointestinal tract. In this ...
Taniguchi, Tomoya; Hirowatari, Anna; Ikeda, Takeshi; Fukuyama, Masataka; Amemiya, Yoshiteru; Kuroda, Akio; Yokoyama, Shin
OPTICS COMMUNICATIONS   365 16-23   Apr 2016   [Refereed]
Biosensors using ring resonators with silicon nitride (SiN) slot waveguides have been fabricated. The temperature coefficient of the resonance wavelength of the SiN resonator is 0.006 nm/degrees C, which is one order of magnitude smaller than that...
Taniguchi, Tomoya; Yokoyama, Shuhei; Amemiya, Yoshiteru; Ikeda, Takeshi; Kuroda, Akio; Yokoyama, Shin
JAPANESE JOURNAL OF APPLIED PHYSICS   55(4)    Apr 2016   [Refereed]
Differential Si ring optical resonator sensors have been fabricated. Their detection sensitivity was 10(-3) -10(-2)% for sucrose solution, which corresponds to a sensitivity of similar to 1.0 ng/ml for prostate-specific antigen (PSA), which is sat...
Motomura, Kei; Ikeda, Takeshi; Matsuyama, Satoshi; Abdelhamid, Mohamed A. A.; Tanaka, Tatsuya; Ishida, Takenori; Hirota, Ryuichi; Kuroda, Akio
JOURNAL OF BACTERIOLOGY   198(2) 276-282   Jan 2016   [Refereed]
Silica is deposited in and around the spore coat layer of Bacillus cereus, and enhances the spore's acid resistance. Several peptides and proteins, including diatom silaffin and silacidin peptides, are involved in eukaryotic silica biomineralizati...
Nakatsuka, Keisuke; Shigeto, Hajime; Kuroda, Akio; Funabashi, Hisakage
BIOSENSORS & BIOELECTRONICS   74 222-226   Dec 2015   [Refereed]
A portable method of specific nucleic acid detection would be very useful for monitoring public health in a variety of settings for point-of-care and point-of-need testing. However, conventional methods for the detection of nucleic acids are not i...
Shigeto, Hajime; Ikeda, Takeshi; Kuroda, Akio; Funabashi, Hisakage
ANALYTICAL CHEMISTRY   87(5) 2764-2770   Mar 2015   [Refereed]
A new homogeneous insulin assay requiring no chemical modification of an insulin recognition domain, which can be applied to continuous monitoring of the time-dependent cellular response in vitro, was developed. The carboxy-terminal alpha-chain (a...
Alexandrov, Maxym; Ichida, Etsuko; Nishimura, Tomoki; Aoki, Kousuke; Ishida, Takenori; Hirota, Ryuichi; Ikeda, Takeshi; Kawasaki, Tetsuo; Kuroda, Akio
An emerging alternative to the commonly used analytical methods for asbestos analysis is fluorescence microscopy (FM), which relies on highly specific asbestos-binding probes to distinguish asbestos from interfering non-asbestos fibers. However, a...
Sekine, Kohei; Yamamoto, Hideaki; Kono, Sho; Ikeda, Takeshi; Kuroda, Akio; Tanii, Takashi
Titanium dioxide (TiO2) photocatalysis can be applied to pattern proteins and cells under aqueous solution. In this work, we extended the application of this technique to patterning primary neurons, a type of cell with relatively weak adhesibility...
Ikeda, Atsushi; Hino, Shodai; Mae, Tomoya; Tsuchiya, Yuki; Sugikawa, Kouta; Tsukamoto, Manami; Yasuhara, Kazuma; Shigeto, Hajime; Funabashi, Hisakage; Kuroda, Akio; Akiyama, Motofusa
RSC ADVANCES   5(127) 105279-105287   2015   [Refereed]
The water-solubilisation of porphyrin derivatives is very important for biological applications. Although liposomal drug carriers for porphyrin derivatives have shown significant promise in the field of medicinal chemistry (e.g., as sensitisers fo...
Funabashi, Hisakage; Shigeto, Hajime; Nakatsuka, Keisuke; Kuroda, Akio
ANALYST   140(4) 999-1003   2015   [Refereed]
A DNA nano-tweezer (DNA-NT) structure-based target mRNA detection probe, which uses fluorescence resonance energy transfer (FRET) as a detection signal and works as a single molecule, has been developed. This FRET-paired fluorescent dye-modified D...
Ikeda, Takeshi; Ueda, Tetsuya; Tajima, Hideji; Sekiguchi, Kiyoshi; Kuroda, Akio
ANALYTICAL METHODS   6(16) 6232-6235   Aug 2014   [Refereed]
An automated enzyme-linked immunosorbent assay (ELISA) system was developed using beads in a single tip (BIST) technology. Sandwich ELISA was performed on glass beads functionalized with a capture antibody via the fusion of antibody-binding strept...
Kanda, Keisuke; Ishida, Takenori; Hirota, Ryuichi; Ono, Satoshi; Motomura, Kei; Ikeda, Takeshi; Kitamura, Kenji; Kuroda, Akio
JOURNAL OF BIOTECHNOLOGY   182 68-73   Jul 2014   [Refereed]
The use of antibiotic resistance markers in the commercial application of genetically modified microorganisms is limited due to restrictions on the release of antibiotics and their resistance genes to the environment. To avoid contamination by oth...


IEEJ Trans. EIS   131(1) 23-28   Jan 2011
Electronics and communications in Japan   92(9) 1498-1503   Oct 2009
Biotechnology Letters.   31(5) 737-741   May 2009
Development of genome engineering technology for solvent-tolerant Rhodococcus opacus strain B4
Proceedings of Asia-Pacific Biochemical Engineering Conference 2007   P3-10   Nov 2007

Books etc

FIBER OPTIC SENSOR Chapter 19: High-sensitivity Detection of Bioluminescnece at an Optical Fiber End for an ATP sensor
Feb 2012   ISBN:9789533079226
ATP regeneration and biological production of phosphorylated compounds using thermostable polyphosphate kinase
Aug 2008   
Basic molecular biology for biotechnology
Nov 2004   ISBN:4759809686
Applications of polyphosphate and other biopolmers in wastewater treatment
Wiley-VCHA= "Biopolymers: Vol.10 General Aspects and Special "Biopolymers: Vol.10 General Aspects and Special Biopolymers: Vol.10 General Aspects and Special Applications (A. Steinbuchel [ed.])   2003   
Applications of polyphosphate and other biopolmers in wastewater treatment.