MISC

2000年6月

Overt congestive heart failure with mitral and aortic regurgitation due to antiphospholipid syndrome in a patient with systemic lupus erythematosus

INTERNAL MEDICINE
  • H Morita
  • ,
  • H Daido
  • ,
  • T Suwa
  • ,
  • T Mune
  • ,
  • K Yoshino
  • ,
  • Y Isomura
  • ,
  • T Tanahashi
  • ,
  • N Takeda
  • ,
  • T Ishizuka
  • ,
  • K Yasuda

39
6
開始ページ
506
終了ページ
511
記述言語
英語
掲載種別
DOI
10.2169/internalmedicine.39.506
出版者・発行元
JAPAN SOC INTERNAL MEDICINE

A 51-year-old woman with overt congestive heart failure with pleural and pericardial effusion was treated with furosemide and nifedipine, leading to improvement in her condition and a decrease in effusions. An echocardiography demonstrated mitral and aortic regurgitation with mitral valve prolapse, which caused the congestive heart failure. Since leukocytopenia and lymphocytopenia with arthralgia could be observed, serological investigations were performed. She was diagnosed as having systemic lupus erythematosus (SLE) with antiphospholipid syndrome, and started;on a treatment of prednisolone and aspirin. Based on the treatment, the pleural and pericardial effusion went into complete remission, indicating that the serositis related to SLE had overlapped the heart failure. Since there was no evidence of any other diseases that could be responsible for the valvular lesions, we concluded that they were due to antiphospholipid syndrome. The administration of prednisolone had no significant effect on valvular morphology or function as demonstrated by echocardiography. When patients with valvular disease are seen, a valvulopathy related to antiphospholipid syndrome should be considered as part of the differential diagnosis.

Web of Science ® 被引用回数 : 6

リンク情報
DOI
https://doi.org/10.2169/internalmedicine.39.506
CiNii Articles
http://ci.nii.ac.jp/naid/10006995199
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/10852175
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000087387500022&DestApp=WOS_CPL