NAGAOKA Satoshi

J-GLOBAL         Last updated: Jul 2, 2019 at 02:42
 
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Name
NAGAOKA Satoshi
Affiliation
Gifu University
Section
Faculty of Applied Biological Sciences
Degree
(BLANK)(Nagoya University), (BLANK)
Research funding number
50202221

Research Areas

 

Academic & Professional Experience

 
 
   
 
Gifu University Faculty of Applied Biological Sciences, Department of Applied Life Science
 

Education

 
 
 - 
1986
Graduate School, Division of Agriculture, Nagoya University
 
 
 - 
1981
Faculty of Agriculture, Utsunomiya University
 

Published Papers

 
Nagaoka Satoshi(Gifu University, Department of Food Science),Awano Takako(Gifu University, Department of Food Science),Nagata Naoko(Gifu University, Department of Food Science),Masaoka Motoki(Gifu University, Department of Food Science),Hori Goro(Kyowa Hakko Kogyo Co., Ltd.),Hashimoto Kei(University of Shizuoka)
61(2) 354-356   Feb 1997
Kanamaru Yoshihiro(Gifu University, Department of Food Science),Ikeda Satoru(Gifu University, Department of Food Science),Yang Shan-Ming(Gifu University, Department of Food Science),Kaneko Tetsuo(Meiji Milk Products),Kuwata Tamotsu(Meiji Milk Products),Nagaoka Satoshi(Gifu University, Department of Food Science),Shimizu Makoto(University of Tokyo),Sachdev GoverdhanP.(University ofOklahoma)
249(3) 618-623   Aug 1998
SREBP-1 binds to multiple sites and transactivates the human apoA-?promoter in vitro. SREBP-1 mutants defective in DNA binding or transcriptional acitvation repress ApoA-II promoter activity.
Pissios Pavlos(Boston University Medical Center),Kan Horng-Yuan(Boston University Medical Center),Nagaoka Satoshi(Boston University Medical Center),Zannis VassilisI.(Boston University Medical Center)
19 1456-1469   Jun 1999
Satoshi Nagaoka(Gifu University, Department of Food Science),Miwa Keiji(Gifu University, Department of Food Science),Eto Michiko(Gifu University, Department of Food Science),Kuzuya Yasuo(Gifu University, Department of Food Science),Hori Goro(Kyowa Hakko Kogyo Co., Ltd.),Yamamoto Kazuhiro(Kyowa Hakko Kogyo Co., Ltd.)
129(9) 1725-1730   Sep 1999
Soyprotein peptic hydrolyzate with bound phospholipids decreasesmicellar solubility and cholesterol absorption in rats and Caco-2 cells.
22(3) 21-27   Mar 2000

Misc

 
Koji Nakade, Hideki Kaneko, Takao Oka, Abdulatef M. Ahhmed, Michio Muguruma, Masahiro Numata, Satoshi Nagaoka
Bioscience, Biotechnology and Biochemistry   73 607-612
The mechanism for the hypocholesterolemic action of a cattle heart protein hydrolysate (HPH) is clarified. The micellar solubility of cholesterol in vitro was significantly lower in the presence of HPH than in the presence of casein. The suppressi...
Yoshihiro Kanamaru, Satoru Ikeda, Shan Ming Yang, Tetsuo Kaneko, Tamotsu Kuwata, Satoshi Nagaoka, Makoto Shimizu, Goverdhan P. Sachdev
Biochemical and Biophysical Research Communications   249(3) 618-623
A monoclonal antibody (mAb; a mouse IgM referred to as 1CF11) recognizing various human glycoproteins was obtained. While the immunoreaction of glycoproteins from human secretions including milk, saliva, and bronchus was demonstrated as a typical ...
Satoshi Nagaoka, Kazuo Shimizu, Hideki Kaneko, Fumi Shibayama, Kensei Morikawa, Yoshihiro Kanamaru, Ayako Otsuka, Tomohiro Hirahashi, Toshimitsu Kato
Journal of Nutrition   135 2425-2430
This study was designed to clarify the mechanisms of the hypocholesterolemic action of Spirulina platensis concentrate (SPC) and identify the novel hypocholesterolemic protein derived from SPC. We investigated the effects of casein or SPC on the s...
Kensei Morikawa, Itsuo Kondo, Yoshihiro Kanamaru, Satoshi Nagaoka
Biochemical and Biophysical Research Communications   352 697-702
Our group previously discovered a novel hypocholesterolemic pentapeptide (IIAEK: Ile-Ile-Ala-Glu-Lys, or what we describe as "lactostatin") derived from bovine milk β-lactoglobulin. To clarify the mechanism of the hypocholesterolemic action of lac...
Mai Hirose, Taishi Ando, Rahman Shofiqur, Kouji Umeda, Yoshikatsu Kodama, Sa Van Nguyen, Tsuyoshi Goto, Masaya Shimada, Satoshi Nagaoka
Nutrition and Metabolism   10 
Background: There is completely no report about both hen egg anti-lipase immunoglobulin yolk (IgY) and its anti-obesity action. Thus, we tried to isolate and characterize a novel anti-lipase immunoglobulin from hen egg yolk. Moreover, we investiga...

Books etc

 
Physiological properties of 4-chlorotryptophan, a novel natural chloroamino acid
Amino Acids ; Chemistry Biology and Medicine   1990   
Identification of two molecular species in human milk-derived lactoferrir
Loctoferrine: Structure, Function and Applications   2000   
Cholesterol-lowering proteins and peptides. “Neutraceutical Proteins and Peptides in Health and Disease”
Feb 2006   
食品機能性の科学(大豆タンパク質・ペプチド)
Apr 2008   
種子のバイオサイエンス(改訂版)、8-1-5 ダイズの生理機能性ペプチド
Feb 2009   

Conference Activities & Talks

 
Comparative studies on the improving effects of cholesterolmetabolism induced by soyprotein sumizyme hydrolysate with bound phospholipids or chitosan. [Invited]
Nagaoka Satoshi(Gifu University, Department of Food Science),Ishikawa Hironobu(Gifu University, Department of Food Science),Shibayama Fumi(Gifu University, Department of FoodScience),Hori Goro(Kyowa Hakko Kogyo Co., Ltd.),Hara Takahiro(Kyowa Hakko Kogyo Co., Ltd.),Yamamoto Kazuhiro(Kyowa Hakko Kogyo Co., Ltd.)
Oct 2000   
Development of transgenic rice accumulating α´ subunit of soybean β-conglycinin in a low glutelin mutant of'Koshihikari'rice variety
3rd International Symposium on Frontiers in Agriculture Proteome Research   Nov 2011   
Identification of Novel Hypocholesterolemic Peptide Derived from Bovine Milk β-Lactoglobulin [Invited]
Nagaoka Satoshi(Gifu University, Department ofFoodScience),Futamura Yu(Gifu University, Department of Food Science),MiwaKeiji(Gifu University, Department of Food Science),Awano Takako(Gifu University, Department of Food Science),Yamauchi Kouhei(Gifu University, Department of Food Science),Kanamaru Yoshihiro(Gifu University, Department of Food Science),Kojima Tadashi(Meiji Milk Products),Kuwata Tamotsu(Meiji Milk Products)
Apr 2001   
Improvements in cholesterol metabolism induced by soypeptides with bound phospholipids. [Invited]
Nagaoka Satoshi(Gifu University, Department ofFood Science),Hori Goro(Kyowa Hakko Kogyo Co., Ltd.),Yamamoto Kazuhiro(Kyowa Hakko Kogyo Co., Ltd.),Yamamoto Kohei(Kyowa Foods Inc., USA),Yamamoto Shigeru(Tokushima University)
May 2003   
New Cholesterol-Lowering Peptides Derived from Food Proteins. [Invited]
Nagaoka Satoshi(Gifu University, Department of Food Science)
May 2004   

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2011 - 2013    Investigator(s): Satoshi NAGAOKA
We used the luciferase plasmid containing the cholesterol transporter, intestinal ABCA1 gene promoter to clarify the molecular mechanism of the inhibition of intestinal cholesterol absorption by lactostatin in Caco-2 cells. Our results suggested t...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2008 - 2010    Investigator(s): Satoshi NAGAOKA
[1] This experiment was designed to identify the peptides that have bile acid-binding ability from soybean protein to inhibit an intestinal cholesterol absorption by peptide array. We found some bile acid binding peptides in this screening. Furthe...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2002 - 2003    Investigator(s): Satoshi NAGAOKA
Generally, animal proteins known as casein and else are considered to cause atherosclerosis in comparison with vegetable proteins. However, we have shown bovine milk whey protein which is animal protein and its major constituent protein β-lactoglo...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2000 - 2001    Investigator(s): Satoshi NAGAOKA
As the structure of the isoflavonoids is similar to that of estrogen and isoflavonoids has a estrogenic activity, the beneficial effects of dietary soy isoflavonoids on atherosclerosis, cancer, osteoporosis has been extensively reported. As it is ...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 1998 - 1999    Investigator(s): Satoshi NAGAOKA
1. (1) In the study about anti-atherogenic factors, effects of polyphenol on apolipoprotein A-I (ApoA-I) gene expression were studied. The results demonstrated that soy genistein increases ApoA-I secretion and its mRNA levels in HepG2 cells. (2) G...