HITOMI, Kiyotaka

J-GLOBAL         Last updated: Nov 15, 2019 at 02:57
 
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Name
HITOMI, Kiyotaka
E-mail
hitomips.nagoya-u.ac.jp
Affiliation
Nagoya University
Section
Graduate School of Pharmaceutical Sciences Department of Basic Medicinal Sciences Bioscience
Job title
Professor

Academic & Professional Experience

 
Mar 2007
   
 
Assistant Professor, Graduate School of Bioagricultural Sciences Department of Applied Molecular Biosciences, Nagoya University
 
Apr 2007
 - 
Mar 2012
Associate professor, Graduate School of Bioagricultural Sciences Department of Applied Molecular Biosciences, Nagoya University
 
Apr 2012
 - 
Today
Professor, Graduate School of Pharmaceutical Sciences Department of Basic Medicinal Sciences Bioscience, Nagoya University
 

Education

 
Apr 1986
 - 
Mar 1989
Food Science and Chemistry, Graduate School, Division of Agriculture, Kyoto University
 

Published Papers

 
Ito Yoshimasa, Tatsukawa Hideki, Yamaguchi Hisateru, Takahashi Kazuo, Hitomi Kiyotaka, Yuzawa Yukio
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS   660 11-19   Dec 2018
ISOZYME-SPECIFIC IDENTIFICATION AND CHARACTERIZATION OF SUBSTRATES CROSSLINKED BY TRANSGLUTAMINASES IN LIVER FIBROSIS
Tatsukawa H., Nakagawa H., Hitomi K.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH   42 33A-33A   Aug 2018
Higher susceptibility to osmolality of the medaka (Oryzias latipes) mutants in orthologue genes of mammalian skin transglutaminases.
Watanabe Y., Furukawa E. Tatsukawa H., Hashimoto H., Kamei Y., Taniguchi Y., Hitomi K.,
Biosci. Biotechnol. Biochem   82(7) 1165-1168   Jul 2018   [Refereed]
A granular parakeratosis animal model created by topical aluminum showed characteristic keratinocyte differentiation abnormalities including abnormal profilaggrin processing and cornified cell envelop formation
Fujii M., Kishibe M., Ueda J., Hitomi K., Ishida-Yamamoto A.
JOURNAL OF INVESTIGATIVE DERMATOLOGY   138(5) S68-S68   May 2018
Isozyme-specific comprehensive characterization of transglutaminase-crosslinked substrates in kidney fibrosis.
Tatsukawa H, Otsu R, Tani Y, Wakita R, Hitomi K.
Sci Rep   9(8) 7306   May 2018   [Refereed]

Books etc

 
Preferred Substrate Structure of Transglutaminases
Kiyotaka Hitomi, Hideki Tatsukawa
Springer   Mar 2016   ISBN:978-4-431-55823-1
Identification and application of the preferred substrate peptides for transglutaminases
Aug 2009   
*Preferred substrate sequences for transglutaminase 2: screening using a phage-displayed peptide library
Hitomi, K., Kitamura, M. Sugimura, Y. (Part:Joint Work)
Amino Acids,   Apr 2009   
Animal Cell Technology 15:Characterization of highly reactive sequences for transglutaminase 2 and factor XIIIa
Sugimura Y., Kitamura M., Hosono H., Shibata, H., Maki M. and Hitomi K (Part:Joint Work)
Kluwar Academic Publishers   2008   
Animal Cell Technology 14: Immunological Analysis of Epidermal-type Transglutaminase (TGase 3) in Epithelium.
Kiyotaka Hitomi, Kanae Yamamoto, Koji Nishi, Yoshiaki Sugimura, and Masatoshi Maki (Part:Joint Work)
Kluwar Academic Publishers   2006   

Association Memberships

 
 

Research Grants & Projects

 
Studies on utitlities of high reactivity substrate peptides for glue-peptide
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research
Project Year: Jul 2011 - Mar 2013
Molecular characterization of protein cross-linking reaction for cellular functions
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research
Project Year: Jul 2011 - Mar 2014
Multiple application of cross-linking enzyme activity in life science
Grants-in-Aid for Scientific Research
Project Year: Nov 2008 - Mar 2011
Molecular basis of formation of corneocyte in skin epidermis
Grants-in-Aid for Scientific Research
Project Year: Jul 2005 - Feb 2007
Analysis of activation mechanism of transglutaminase in skin epidermis
Grants-in-Aid for Scientific Research
Project Year: Jul 2000 - Jan 2002