ENDO, Toshiya

J-GLOBAL         Last updated: Dec 29, 2018 at 18:51
ENDO, Toshiya
Kyoto Sangyo University
Faculty of Life Sciences, Department of Molecular Biosciences, Faculty of Life Sciences, Department of Molecular Biosciences

Research Areas


Academic & Professional Experience

Nagoya University Graduate School of Science, Division of Material Science, Division of Material Science,Graduate School of Science,Nagoya University,  Professor

Published Papers

Tamura Y, Kawano S, Endo T
Journal of biochemistry      Oct 2018   [Refereed]
Jores T, Lawatscheck J, Beke V, Franz-Wachtel M, Yunoki K, Fitzgerald JC, Macek B, Endo T, Kalbacher H, Buchner J, Rapaport D
The Journal of cell biology   217(9) 3091-3108   Sep 2018   [Refereed]
Kakimoto Y, Tashiro S, Kojima R, Morozumi Y, Endo T, Tamura Y
Scientific reports   8(1) 6175   Apr 2018   [Refereed]
Endo T, Tamura Y, Kawano S
Aging   10(4) 528-529   Apr 2018   [Refereed]
Kawano S, Tamura Y, Kojima R, Bala S, Asai E, Michel AH, Kornmann B, Riezman I, Riezman H, Sakae Y, Okamoto Y, Endo T
The Journal of cell biology   217(3) 959-974   Mar 2018   [Refereed]
Endo T, Tamura Y
The EMBO journal   37(4)    Feb 2018   [Refereed]
Matsumura A, Higuchi J, Watanabe Y, Kato M, Aoki K, Akabane S, Endo T, Oka T
FEBS letters   592(2) 209-218   Jan 2018   [Refereed]
Tamura Y, Endo T
Advances in experimental medicine and biology   997 121-133   2017   [Refereed]
Suzuki T, Iida N, Suzuki J, Watanabe Y, Endo T, Hisabori T, Yoshida M
FEBS open bio   6(12) 1267-1272   Dec 2016   [Refereed]
Kojima R, Kajiura S, Sesaki H, Endo T, Tamura Y
FEBS letters   590(18) 3061-3070   Sep 2016   [Refereed]
Arakawa S, Yunoki K, Izawa T, Tamura Y, Nishikawa S, Endo T
Scientific reports   6 30795   Aug 2016   [Refereed]
Kojima R, Endo T, Tamura Y
Scientific reports   6 30777   Jul 2016   [Refereed]
Miyata N, Watanabe Y, Tamura Y, Endo T, Kuge O
The Journal of cell biology   214(1) 77-88   Jul 2016   [Refereed]
Jores T, Klinger A, Groß LE, Kawano S, Flinner N, Duchardt-Ferner E, Wöhnert J, Kalbacher H, Endo T, Schleiff E, Rapaport D
Nature communications   7 12036   Jun 2016   [Refereed]
Shiota T, Imai K, Qiu J, Hewitt VL, Tan K, Shen HH, Sakiyama N, Fukasawa Y, Hayat S, Kamiya M, Elofsson A, Tomii K, Horton P, Wiedemann N, Pfanner N, Lithgow T, Endo T
Science (New York, N.Y.)   349(6255) 1544-1548   Sep 2015   [Refereed]
Watanabe Y, Tamura Y, Kawano S, Endo T
Nature communications   6 7922   Aug 2015   [Refereed]
Maruyama D, Endo T, Nishikawa S
Plant signaling & behavior   10(7) e1035853   2015   [Refereed]
Different sets of ER-resident J-proteins regulate distinct polar nuclear-membrane fusion events in Alabidopsis thaliana
D. Maruyama, M. Yamamoto, T. Endo, and S. Nishikawa
Plant Cell Physiol.   55(11) 1937-1944   Nov 2014   [Refereed]
Maruyama D, Yamamoto M, Endo T, Nishikawa S
Plant & cell physiology   55(11) 1937-1944   Nov 2014   [Refereed]
Kuroki H, Miyagawa Y, Shimomura-Kuroki J, Endo T, Shimomura H
Odontology   102(2) 303-309   Jul 2014   [Refereed]
Maruyama D, Sugiyama T, Endo T, Nishikawa S
Plant & cell physiology   55(4) 801-810   Apr 2014   [Refereed]
Okamoto H, Miyagawa A, Shiota T, Tamura Y, Endo T
The Journal of biological chemistry   289(8) 4827-4838   Feb 2014   [Refereed]
Ubiquitin is phosphorylated by PINK1 to activate parkin.
F. Koyano, K. Okatsu, H. Kosako, Y. Tamura, E. Go, M. Kimura, Y. Kimura, H. Tsuchiya, H. Yoshihara, T. Hirokawa, T. Endo, E. A. Fon, J. F. Trempe, Y. Saeki, K. Tanaka, and N. Matsuda
Nature   210 162-166   2014   [Refereed]
Endo Toshiya
YEAST   30 23   Sep 2013   [Refereed]
Shiota T, Nishikawa S, Endo T
Methods in molecular biology (Clifton, N.J.)   1033 207-217   2013   [Refereed]
Tamura Y, Onguka O, Itoh K, Endo T, Iijima M, Claypool SM, Sesaki H
The Journal of biological chemistry   287(52) 43961-43971   Dec 2012   [Refereed]
Izawa T, Tsuboi T, Kuroha K, Inada T, Nishikawa S, Endo T
Cell reports   2(3) 447-453   Sep 2012   [Refereed]
Phosphatidylethanolamine biogenesis in mitochondria: phosphatidylserine (PS) trafficking is independent of a PS decarboxylase and intermembrane space proteins, Ups1p and Ups2p.
Y. Tamura, O. Onguka, K. Itoh, T. Endo, M. Iijima, S. M. Claypool, H. Sesaki
Journal of Biological Chemistry   287 43961-43971   2012   [Refereed]
The Tom40 assembly process probed using the attachment of different intra-mitochondrial sorting signals.
T. Shiota*, M. Maruyama*, M. Miura*, Y. Tamura*, K. Yamano, M. Esaki, and T. Endo
Molecular Biology of the Cell   23 3936-3947   2012   [Refereed]
Role of Dom34:Hbs1 in non-stop protein clearance for normal organelle protein influxCell Reports
T. Izawa, T. Tsuboi, K. Kuroha, T. Inada, S. Nishikawa, and T. Endo
Cell Reports   2 447-453   2012   [Refereed]
Yos9p and Hrd1p mediate ER retention of misfolded proteins for ER-associated degradation
Toshiaki Izawa, Hiroyuki Nagai, Toshiya Endo, and Shuh-ichi Nishikawa
Mol. Biol. Cell   23 1283-1293   2012   [Refereed]
Mori S, Kajita T, Endo T, Yoshihisa T
RNA (New York, N.Y.)   17(9) 1760-1769   Sep 2011   [Refereed]
Botelho Salome Calado, Osterberg Marie, Reichert Andreas S., Yamano Koji, Bjorkholm Patrik, Endo Toshiya, von Heijne Gunnar, Kim Hyun
EMBO JOURNAL   30(6) 1003-1011   Mar 2011   [Refereed]
Endo Toshiya, Kawano Shin, Yamano Koji
EMBO REPORTS   12(2) 94-95   Feb 2011   [Refereed]
The intron of tRNA-TrpCCA is dispensable for growth and translation of Saccharomyces cerevisia
S. Mori, T. Kajita, T. Endo, and T. Yoshihisa
RNA   17 1760-1769   2011   [Refereed]
In vivo protein-interaction mapping of a mitochondrial translocator protein Tom22 at work
T. Shiota, H. Mabuchi, S. Tanaka-Yamano, K. Yamano, and T. Endo
Proc. Natl. Acad. Sci. USA   108 15179-15183   2011   [Refereed]
TIM23-mediated insertion of transmembrane α-helices into the mitochondrial inner membrane
S.C. Botelho, M. Osterberg, A.S. Reichert, K. Yamano, P. Bjorkholm, T. Endo, G. von Heijne, and H. Kim
EMBO J.   in press   2011   [Refereed]
Structural insight into the mitochondrial protein import system
T. Endo, K. Yamano, and S. Kawano
Biochim. Biophys. Acta (Biomembranes)   in press   2011   [Refereed]
BamE structure: the assembly of β-barrel proteins in the outer membranes of bacteria and mitochondria
T. Endo, S. Kawano, and K. Yamano
EMBO Rep.   12 94-95   2011   [Refereed]
Dual role of the receptor Tom20 in specificity and efficiency of protein import into mitochondria
H. Yamamoto, N. Itoh, S. Kawano, Y. Yatsukawa, T. Momose, T. Makio, M. Matsunaga, M. Yokota, M. Esaki, T. Shodai, D. Kohda, A.E.A. Hobbs, R.E. Jensen, and T. Endo
Proc. Natl. Acad. Sci. USA   108 91-96   2011   [Refereed]
Yagawa K, Yamano K, Oguro T, Maeda M, Sato T, Momose T, Kawano S, Endo T
Protein science : a publication of the Protein Society   19(4) 693-702   Apr 2010   [Refereed]
Tom7 regulates Mdm10-mediated assembly of the mitochondrial import channel protein Tom40
K. Yamano, S. Tanaka-Yamano, and T. Endo
J. Biol. Chem.   285 41222-41231   2010   [Refereed]
Dual functions of yeast tRNA ligase in the unfolded protein response: unconventional cytoplasmic splicing of HAC1 pre-mRNA is not sufficient to release translational attenuation
T. Mori, C. Ogasawara, T. Inada, M. Englert, H. Beier, M. Takezawa, T. Endo, and T. Yoshihisa
Mol. Biol. Cell   21 3722-3734   2010   [Refereed]
Mitochondrial matrix reloaded with RNA
T. Endo, K. Yamano, and T. Yoshihisa
Cell   142 363-363   2010   [Refereed]
Structural basis for the disulfide relay system in the mitochondrial intermembrane space
T. Endo, K. Yamano, and S. Kawano
Antioxid. Redox Signal.   13 1359-1373   2010   [Refereed]
On the impact of precursor unfolding during protein import into chloroplasts
M. Ruprecht, T. Bionda, T. Sato, M.S. Sommer, T. Endo, and E. Schleiff
Mol. Plant   3 499-508   2010   [Refereed]
A vacuolar carboxypeptidase mutant of Arabidopsis thaliana is degraded by the ERAD pathway independently of its N-glycan
M. Yamamoto, M. Kawanabe, Y. Hayashi, T. Endo, and S. Nishikawa
Biochem. Biophys. Res. Commun.   393 384-389   2010   [Refereed]
Structural basis for unfolding pathway-dependent stability of proteins: vectorial unfolding vs. global unfolding
K. Yagawa, K. Yamano, T. Oguro, M. Maeda, T. Sato, T. Momose, S. Kawano, and T. Endo
Protein Science   in press   2010   [Refereed]
Identification of yeast Art5 as a multicopy suppressor for the mitochondrial translocator maintenance protein Tam41.
Y. Harada, Y. Tamura, and T. Endo
Biochem. Biophys. Res. Commun.   in press   2010   [Refereed]
Mdm10 as a dynamic constituent of the TOB/SAM complex directs coordinated assembly of Tom40.
K. Yamano, S. Tanaka-Yamano, and T. Endo
EMBO Rep.   in press   2010   [Refereed]
Bip-mediated polar nuclei fusion is essential for the regulation of endosperm nuclei proliferation in Arabidopsis thaliana.
D. Maruyama, T. Endo, and S. Nishikawa
Proc. Natl. Acad. Sci. USA   in press   2010   [Refereed]
Transport of proteins across or into the mitochondrial outer membrane
T. Endo and K. Yamano
Biochim. Biophys. Acta (Molecular Cell Research)   in press   2010   [Refereed]
Kawano Shin, Yamano Koji, Naoe Mari, Momose Takaki, Terao Kayoko, Nishikawa Shuh-ichi, Watanabe Nobuhisa, Endo Toshiya
Kawano S, Yamano K, Naoé M, Momose T, Terao K, Nishikawa S, Watanabe N, Endo T
Proceedings of the National Academy of Sciences of the United States of America   106(34) 14403-14407   Aug 2009   [Refereed]
Sakoh-Nakatogawa M, Nishikawa S, Endo T
The Journal of biological chemistry   284(18) 11815-11825   May 2009   [Refereed]
Endo T, Ariga H, Matsumoto K
Molecular and cellular biochemistry   320(1-2) 53-66   Jan 2009   [Refereed]
Roles of TOM70 in import of presequence-containing mitochondrial proteins
H. Yamamoto, K. Fukui, H. Takahashi, S. Kitamura, T. Shiota, K. Terao, M. Uchida, M. Esaki, S. Nishikawa, T. Yoshihisa, K. Yamano, and T. Endo
J. Biol. Chem.   284 31635-31646   2009   [Refereed]
Structural basis of yeast Tim40 as an oxidative translocator in the mitochondrial intermembrane space
S. Kawano, K. Yamano, M. Naoe, T. Momose, K. Terao, S. Nishikawa, N. Watanabe, and T. Endo
Proc. Natl. Acad. Sci. USA   106 14403-14407   2009   [Refereed]
Multiple pathways for mitochondrial protein traffic
T. Endo and K. Yamano
Biol. Chem.   390 723-730   2009   [Refereed]
Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria
Y. Tamura, T. Endo, M. Iijima, and H.Sesaki
J. Cell Biol.   185 1029-1045   2009   [Refereed]
Roles of protein disulfide isomerase-mediated disulfide bond formation of yeast Mnl1p in ER-associated degradation
M. Sakoh-Nakatogawa, S. Nishikawa, and T. Endo
J. Biol. Chem.   284 11815-11825   2009   [Refereed]
Tim23-Tim50 pair coordinates functions of translocators and motor proteins in mitochondrial protein import
Y. Tamura, Y. Harada, T. Shiota, K. Yamano, K. Watanabe, M. Yokota, H. Yamamoto, H. Sesaki, and T. Endo
J. Cell Biol.   184 129-141   2009   [Refereed]
Structural stabilities of different regions of the titin I27 domain contribute differently to unfolding upon mitochondrial protein import
T. Oguro, K. Yagawa, T. Momose, T. Sato, K. Yamano, and T. Endo
J. Mol. Biol.   385 811-819   2009   [Refereed]
Endo Toshiya
Nuclear inner membrane fusion facilitated by yeast Jem1p is required for spindle pole body fusion but not for the first mitotic nuclear division during yeast mating
S. Nishikawa, A. Hirata, and T. Endo
Genes Cells   13 1185-1195   2008   [Refereed]
Arabidopsis thaliana has a set of J proteins in the endoplasmic reticulum that are conserved from yeast to animals and plants
M. Yamamoto, D. Maruyama, T. Endo, and S. Nishikawa
Plant Cell Physiol.   49 1547-1562   2008   [Refereed]
Step size analyses of the mitochondrial Hsp70 import motor reveal the Brownian ratchet in operation
K. Yamano, M. Kuroyanagi-Hasegawa, M. Esaki, M. Yokota, and T. Endo
J.Biol. Chem.   283 27325-27332   2008   [Refereed]
Identification and characterization of a Jem1p ortholog of Candida albicans: dissection of Jem1p functions in karyogamy and protein quality control in Saccharomyces cerevisiae
T. Makio, S. Nishikawa, T. Nakayama, H. Nagai, and T. Endo
Genes Cells   13 1015-1026   2008   [Refereed]
Tom20 and Tom22 share the common signal recognition pathway in mitochondrial protein import
K. Yamano, Y. Yatsukawa, M. Esaki, A. E. A Hobbs, R. E. Jensen, and T. Endo
J. Biol. Chem.   283 3799-3807   2008   [Refereed]
Structural basis of functional cooperation of Tim15/Zim17 with yeast mitochondrial Hsp70.
Momose T, Ohshima C, Maeda M, Endo T.
EMBO Rep.   8(7) 664-670   2007   [Refereed]
Cytoplasmic splicing of tRNA in Saccharomyces cerevisiae.
Yoshihisa T, Ohshima C, Yunoki-Esaki K, Endo T.
Genes Cells   12(3) 285-297   2007   [Refereed]
Tom20 recognizes mitochondrial presequences through dynamic equilibrium among multiple bound states
T. Saitoh, M. Igura, T. Obita, T. Ose, R. Kojima, K. Maenaka, T. Endo, and D. Kohda
EMBO J.   26 4777-4787   2007   [Refereed]
Functional analysis of J proteins in the endoplasmic reticulum of Arabidopsis thaliana
Yamamoto Masaya, Maruyama Daisuke, Endo Toshiya, Nishikawa Shuh-ichi
PLANT AND CELL PHYSIOLOGY   48 S154   2007   [Refereed]
Reproduction defects of the T-DNA mutants of endoplasmic reticulum Hsp70 in Arabidopsis thaliana
Maruyama Daisuke, Endo Toshiya, Nishikawa Shuh-ichi
PLANT AND CELL PHYSIOLOGY   48 S153   2007   [Refereed]
[What is the physiological role of nuclear tRNA?].
Yoshihisa T, Takano A, Endo T
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   51(14 Suppl) 2232-2234   Nov 2006   [Refereed]
Identification of Tam41 maintaining integrity of the TIM23 protein translocator complex in mitochondria
Y. Tamura, Y. Harada, K. Yamano, K. Watanabe, D. Ishikawa, C. Ohshima, S. Nishikawa, H. Yamamoto, and T. Endo
J. Cell Biol.   174 615-623   2006   [Refereed]
Identification of Tim40 that mediates protein sorting to mitochondrial intermembrane space
Naoe Mari, Ohwa Yukimasa, Ishikawa Daigo, Olishima Chie, Nishikawa Shuh-ichi, Yamamoto Hayashi, Endo Toshiya
CELL STRUCTURE AND FUNCTION   30 101   Jun 2005   [Refereed]
TRNA actively shuttles between the nucleus and the cytosol in Saccharomyces cerevisiae
Takano OAkira, Endo Toshiya, Yoshihisa Tohru
CELL STRUCTURE AND FUNCTION   30 43   Jun 2005   [Refereed]
Igura M, Ose T, Obita T, Sato C, Maenaka K, Endo T, Kohda D
Acta crystallographica. Section F, Structural biology and crystallization communications   61(Pt 5) 514-517   May 2005   [Refereed]
Yamano K, Ishikawa D, Esaki M, Endo T
The Journal of biological chemistry   280(11) 10011-10017   Mar 2005   [Refereed]
Crystallization and preliminary X-ray analysis of mitochondrial presequence receptor Tom20 in complexes with a presequence from ALDH
Mayumi Igura, Toyoyuki Ose, Takayuki Obita, Chiaki Sato, Katsumi Maenaka, Toshiya Endo and Daisuke Kohda
Acta Cryst   F61 514-517   2005   [Refereed]
Identification of a novel member of yeast mitochondrial Hsp70-associated motor and chaperone proteins that facilitates protein translocation across the inner membrane.
H. Yamamoto, T. Momose, Y. Yatsukawa, C. Ohshima, D. Ishikawa, T. Sato, Y. Tamura, Y. Ohwa and T. Endo
FEBS Lett.   579 507-511   2005   [Refereed]
Phosphate carrier has an ability to be sorted to either the TIM22 pathway or TIM23 pathway for its import into yeast mitochondria.
K. Yamano, D. Ishikawa, M. Esaki, and T. Endo
J. Biol. Chem.   280 10011-10017   2005   [Refereed]
tRNA actively shuttles between the nucleus and cytosol in yeast.
A. Takano, T. Endo, and T. Yoshihisa
Science   309 140-142   2005   [Refereed]
Comparison of the protein unfolding pathways between mitochondrial protein import and atomic force microscopy measurements
T. Sato, M. Esaki, J. M.Fernandez, and T. Endo
Proc. Natl. Acad. Sci. USA   102 17999-18004   2005   [Refereed]
Esaki M, Shimizu H, Ono T, Yamamoto H, Kanamori T, Nishikawa S, Endo T
The Journal of biological chemistry   279(44) 45701-45707   Oct 2004   [Refereed]
Ishikawa D, Yamamoto H, Tamura Y, Moritoh K, Endo T
The Journal of cell biology   166(5) 621-627   Aug 2004   [Refereed]
[Roles of molecular chaperones and carbohydrate chains in the endoplasmic reticulum quality control].
Nishikawa S, Nakatsukasa K, Endo T
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   49(7 Suppl) 988-991   May 2004   [Refereed]
[Protein traffic (in eukaryotic cells): mechanism of operation of the protein-traffic control system in the cell].
Endo T, Yoshihisa T
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   49(7 Suppl) 877-888   May 2004   [Refereed]
Identification of Tim40 that mediates protein sorting to the mitochondrial intermembrane space
M. Naoe, Y. Ohwa, D. Ishikawa, C. Ohshima, S. Nishikawa, H. Yamamoto, and T. Endo
J. Biol. Chem.   279 47815-47821   2004   [Refereed]
Roles of O-mannosylation of aberrant proteins in reduction of the load for endoplasmic reticulum chaperones in yeast
K. Nakatsukasa, S. Okada, K. Umebayashi, R. Fukuda, S. Nishikawa, and T. Endo
J. Biol. Chem.   279 49762-49772   2004   [Refereed]
Mitochondrial protein import: Requirement of the presequence elements and TOM components for precursor binding to the TOM complex
M. Esaki, H. Shimizu, T. Ono, H. Yamamoto, T. Kanamori, S. Nishikawa, and T. Endo
J. Biol. Chem.   279 45701-45707   2004   [Refereed]
Two novel proteins in the mitochondrial outer membrane mediate β-barrel protein assembly
D. Ishikawa, H. Yamamoto, Y. Tamura, K. Moritoh, and T. Endo
J. Cell Biol.   166 621-627   2004   [Refereed]
Re-investigation of the requirement of cytosolic ATP for mitochondrial protein import
T. Asai, T. Takahashi, M. Esaki, S. Nishikawa, K. Ohtsuka, M. Nakai, and T. Endo
J. Biol. Chem.   279 19464-19470   2004   [Refereed]
Protein transport to and within plant chloroplasts
T. Endo
Endocytobiosis Cell Res.   15 294-299   2004   [Refereed]
Yoshihisa T, Yunoki-Esaki K, Ohshima C, Tanaka N, Endo T
Molecular biology of the cell   14(8) 3266-3279   Aug 2003   [Refereed]
Peptide library approach with a disulfide tether to refine the Tom20 recognition motif in mitochondrial presequences.
T. Obita, T. Muto, T. Endo and D. Kohda
J. Mol. Biol.   328 495-504   2003   [Refereed]
Nep98p is a component of the yeast spindle pole body and essential for nuclear division and fusion
S. Nishikawa, Y. Terazawa, T. Nakayama, A. Hirata, T. Makio and T. Endo
J. Biol. Chem.   278 9938-9943   2003   [Refereed]
*Tom40 protein import channel binds to non-native proteins and prevents their aggregation
M. Esaki, T. Kanamori, S. Nishikawa, I. Shin, P. G. Schultz, and T. Endo
Nature Struct. Biol.   10 988-994   2003   [Refereed]
Functional cooperation and separation of translocators in protein import into mitochondria, the double-membrane bounded organelles.
T. Endo, H. Yamamoto, and M. Esaki
J. Cell Science   116 3259-3267   2003   [Refereed]