2014年2月
A design for the control of apoptosis in genetically modified Saccharomyces cerevisiae
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
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- ,
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- 巻
- 78
- 号
- 2
- 開始ページ
- 358
- 終了ページ
- 362
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1080/09168451.2014.878224
- 出版者・発行元
- TAYLOR & FRANCIS LTD
We have engineered a system that holds potential for use as a safety switch in genetically modified yeasts. Human apoptotic factor BAX (no homolog in yeast), under the control of the FBP1 (gluconeogenesis enzyme) promoter, was conditionally expressed to induce yeast cell apoptosis after glucose depletion. Such systems might prove useful for the safe use of genetically modified organisms.
- リンク情報
- ID情報
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- DOI : 10.1080/09168451.2014.878224
- ISSN : 0916-8451
- eISSN : 1347-6947
- PubMed ID : 25036693
- Web of Science ID : WOS:000337573300025