2006年1月
Engineered bio-nanocapsules, the selective vector for drug delivery system
IUBMB LIFE
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- 巻
- 58
- 号
- 1
- 開始ページ
- 1
- 終了ページ
- 6
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1080/15216540500484368
- 出版者・発行元
- TAYLOR & FRANCIS INC
The bio-nanocapsule (BNC) is our concept of artificial hollow nanoparticles that have been designed and produced through biotechnological procedures. We proposed an empty virus-like particle, which consists of a recombinant L envelope protein of hepatitis B virus (HBV) and a lipid derived from the host cell, as an engineered BNC. Although this BNC was first developed as an immunogen of hepatitis B vaccine, the pre-S1 region in N-terminus of L envelope protein confers hepatocyte specific infectivity of HBV on the BNC. This recombinant BNC is now being developed as a novel platform of drug delivery system (DDS) vector for selective delivery.
- リンク情報
- ID情報
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- DOI : 10.1080/15216540500484368
- ISSN : 1521-6543
- Web of Science ID : WOS:000235981500001