Masaaki Hirose - My portal - researchmap

Profile Information

Affiliation: 教授, 旧所属京都大学大学院農学研究科応用生命科学専攻

Degree: Doctor of Agriculture

J-GLOBAL ID: 200901008478814738
researchmap Member ID: 1000027962

Research Interests

2

Research Areas

1

Life sciences / Applied biochemistry /

Education

4

- 1967

Kyoto University
- 1967

Graduate School, Division of Agriculture, Kyoto University
- 1965

Faculty of Agriculture, Kyoto University
- 1965

Faculty of Agriculture, Kyoto University

Misc.

121

Iron-binding process in the amino- and carboxyl-terminal lobes of ovotransferrin: Quantitative studies utilizing single Fe3+-binding mutants

Okamoto, I, K Mizutani, M Hirose

BIOCHEMISTRY, 43(34) 11118-11125, Aug, 2004
Structural and functional characterization of ovotransferrin produced by Pichia pastoris

K Mizutani, Okamoto, I, K Fujita, K Yamamoto, M Hirose

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 68(2) 376-383, Feb, 2004
Crystal structure of S-ovalbumin as a non-loop-inserted thermostabilized serpin form

M Yamasaki, N Takahashi, M Hirose

JOURNAL OF BIOLOGICAL CHEMISTRY, 278(37) 35524-35530, Sep, 2003
Thermostabilization of ovalbumin by an alkaline treatment: Examination for the possible implications of an altered serpin loop structure

H Yamamoto, N Takahashi, M Yamasaki, Y Arii, M Hirose

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 67(4) 830-837, Apr, 2003
Periplasmic secretion of native ovalbumin without signal cleavage in Escherichia coli

Y Arii, N Takahashi, M Hirose

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 67(2) 368-371, Feb, 2003
Refolding mechanism of ovalbumin

The Journal of Biological Chemistry, 278(26) 23600-23609, 2003
Probing the serpin structural transition mechanism in an ovalbumin mutant R339T by proteolytic cleavage kinetics of the reactive center loop

Biochemical Journal, Vol.363, pp.403-409, 2002
Loop-inserted and thermostabilized structure of P1-P1’ cleaved ovalbumin mutant R339T

Journal of Molecular Biology, Vol.307, pp.113–120, 2002
Domain closure mechanism in transferrins

Journal of Molecular Biology, 309(4) 937-947, 2001
Thermostabilization of ovalbumin in a developing egg by an alkalinity-regulated, two-step process

Bioscience Biotechnology and Biochemistry, Vol.65, pp.2021-2027, 2001
Anion-mediated Fe³⁺ release mechanism in ovotransferrin C-lobe: a structurally identified SO₄^2- binding site and its implications for the kinetic pathway

The Journal of Biological Chemistry, Vol.276, pp. 35940-35946, 2001
Structural and functional consequences of removal of the interdomain disulfide bridge from the isolated C-lobe of ovotransferrin

BK Muralidhara, M Hirose

PROTEIN SCIENCE, 9(8) 1567-1575, Aug, 2000
The structural mechanism for iron uptake and release by transferrins

M Hirose

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 64(7) 1328-1336, Jul, 2000
Anion-mediated iron release from transferrins - The kinetic and mechanistic model for N-lobe of ovotransferrin

BK Muralidhara, M Hirose

JOURNAL OF BIOLOGICAL CHEMISTRY, 275(17) 12463-12469, Apr, 2000
Crystal structure at 1.9 angstrom resolution of the apoovotransferrin N-lobe bound by sulfate anions: Implications for the domain opening and iron release mechanism

K Mizutani, H Yamashita, B Mikami, M Hirose

BIOCHEMISTRY, 39(12) 3258-3265, Mar, 2000
鉄輸送蛋白質トランスフェリン‐その構造と機能の接点を探る

京都大学食糧科学研究所報告, Vol.63, pp.43-44, 2000
Crystal structure of hen apo-ovotransferrin - Both lopes adopt an open conformation upon loss of iron

H Kurokawa, JC Dewan, B Mikami, JC Sacchettini, M Hirose

JOURNAL OF BIOLOGICAL CHEMISTRY, 274(40) 28445-28452, Oct, 1999
Structural properties of recombinant ovalbumin and its transformation into a thermostabilized form by alkaline treatment

Y Arii, N Takahashi, E Tatsumi, M Hirose

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 63(8) 1392-1399, Aug, 1999
Alternative structural state of transferrin - The crystallographic analysis of iron-loaded but domain-opened ovotransferrin N-lobe

K Mizutani, H Yamashita, H Kurokawa, B Mikami, M Hirose

JOURNAL OF BIOLOGICAL CHEMISTRY, 274(15) 10190-10194, Apr, 1999
Conformational state of disulfide-reduced ovalbumin at acidic pH

Eizo TATSUMI, Daisuke YOSHIMATSU, Masaaki HIROSE

Bioscience, Biotechnology and Biochemistry, 63(7) 1285-1290, 1999

More

Books and Other Publications

15

Egg white proteins, ovalbumin

Progress in Biotechnology, Elsevier, 2003
タンパク質のコンフォメーション概説（神経難病の分子機構）

シュプリンガー・フェアラーク東京, 2000
アミノ酸、タンパク質（食品化学）

文永堂出版, 1992
ホルモン作用の分子機構（医科分子生物学）

南江堂, 1991
遺伝子発現とその調節（新生理科学大系第６巻細胞小器官の生理学）

医学書院, 1991
ホルモンレセプターとクロマチンの相互作用の分析法（クロマチン実験法）

学会出版センター, 1988
食品群の栄養的特長（食物栄養学）

培風館, 1986
Biochemical response to hormone action in mammary gland nuclei, in″Molecular mechanism of biosignal transduction″

Center for Academic Publication, Tokyo, 1986
Correlation between hormoue-mediated messengerRNA induction and nuclear histone acetylation. in″Glucocorticoid hormone mechanism of action″

Japan Scientific Society Press, Tokyo, 1986
動物性の食品材料とその加工品（食品学）

朝倉書店, 1983
クロマチンの機能的構造と転写（クロマチン）

講談社サイエンティフィク, 1979
エストロゲン・プロゲステロンの作用機序（ステロイドホルモンの生物化学）

学会出版センター, 1978
Steroid hormoneの作用機序（ホルモンの作用機序）

医歯薬出版, 1977
ホルモンによる誘導機構（細胞生物学第7巻細胞の分化）

理工学社, 1977
Regulation of transcription of the eukdryotic genome. In'The molecular Biology of Hormone Action'

Academic Press, New York, 1976

Professional Memberships

7

Research Projects

4