J-GLOBAL         Last updated: Aug 17, 2019 at 17:11
Kyoto University
Graduate School of Agriculture, Division of Food Science and Biotechnology
Job title
Master of Agriculture, Doctor of Agriculture

Research Areas



Graduate School, Division of Agriculture, Kyoto University
Faculty of Agriculture, Kyoto University

Published Papers

Matsumura S, Odanaka M, Ishikawa F, Sasaki T, Manio MCC, Fushiki T, Inoue K
Physiology & behavior   204 112-120   Jan 2019   [Refereed]
Hashimoto O, Funaba M, Sekiyama K, Doi S, Shindo D, Satoh R, Itoi H, Oiwa H, Morita M, Suzuki C, Sugiyama M, Yamakawa N, Takada H, Matsumura S, Inoue K, Oyadomari S, Sugino H, Kurisaki A
Cell reports   25(5) 1193-1203   Oct 2018   [Refereed]
Matsumura S, Ishikawa F, Sasaki T, Odanaka M, Manio MCC, Fushiki T, Inoue K
Molecular nutrition & food research   e1800241   Sep 2018   [Refereed]
Irahara T, Sato N, Otake K, Matsumura S, Inoue K, Ishihara K, Fushiki T, Yokota H
The Journal of surgical research   227 44-51   Jul 2018   [Refereed]
Manio MC, Matsumura S, Inoue K
Journal of the International Society of Sports Nutrition   15(1) 29   Jun 2018   [Refereed]
Mori N, Kurata M, Yamazaki H, Matsumura S, Hashimoto T, Kanazawa K, Nadamoto T, Inoue K, Fushiki T
Bioscience, biotechnology, and biochemistry   82(4) 698-708   Apr 2018   [Refereed]
Tsuzuki S, Kimoto Y, Lee S, Sugawara T, Manabe Y, Inoue K
Biomedical research (Tokyo, Japan)   39(3) 117-129   2018   [Refereed]
Amitsuka T, Okamura M, Mukuta K, Shiibashi H, Haraguchi K, Saito T, Inoue K, Fushiki T
Bioscience, biotechnology, and biochemistry   81(8) 1561-1568   Aug 2017   [Refereed]
Tsuzuki S, Amitsuka T, Okahashi T, Kimoto Y, Inoue K
Journal of agricultural and food chemistry   65(31) 6647-6655   Aug 2017   [Refereed]
Tsuzuki S, Yamasaki M, Kozai Y, Sugawara T, Manabe Y, Inoue K, Fushiki T
Journal of biochemistry      May 2017   [Refereed]
Lee S, Tsuzuki S, Amitsuka T, Masuda D, Yamashita S, Inoue K
Biomedical research (Tokyo, Japan)   38(3) 207-213   2017   [Refereed]
Hatazawa Y, Minami K, Yoshimura R, Onishi T, Manio MC, Inoue K, Sawada N, Suzuki O, Miura S, Kamei Y
Biochemical and biophysical research communications   481(3-4) 251-258   Dec 2016   [Refereed]
Irahara T, Sato N, Inoue K, Otake K, Ohtsuru S, Koike K, Fushiki T, Yokota H
The journal of trauma and acute care surgery      Mar 2016   [Refereed]
Manio MC, Inoue K, Fujitani M, Matsumura S, Fushiki T
Physiological reports   4(5)    Mar 2016   [Refereed]
Kobayashi K, Tanaka T, Okada S, Morimoto Y, Matsumura S, Manio MC, Inoue K, Kimura K, Yagi T, Saito Y, Fushiki T, Inoue H, Matsumoto M, Nabeshima Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology   30(2) 849-862   Feb 2016   [Refereed]
Tsuzuki S, Amitsuka T, Okahashi T, Kozai Y, Matsumura S, Inoue K, Fushiki T
Bioscience, biotechnology, and biochemistry   1-4   Feb 2016   [Refereed]
Zheng M, Lee S, Tsuzuki S, Inoue K, Masuda D, Yamashita S, Iwanaga T
Biomedical research (Tokyo, Japan)   37(4) 265-270   2016   [Refereed]
Tsuzuki S, Amitsuka T, Okahashi T, Kozai Y, Yamasaki M, Inoue K, Fushiki T
Biomedical research (Tokyo, Japan)   37(6) 335-342   2016   [Refereed]
Hiroya Ohta, Morichika Konishi, Morichika Konishi, Yusuke Kobayashi, Atsuki Kashio, Takayuki Mochiyama, Shigenobu Matsumura, Kazuo Inoue, Tohru Fushiki, Kazuwa Nakao, Ikuo Kimura, Ikuo Kimura, Nobuyuki Itoh
Scientific Reports   5    May 2015   [Refereed]
Some neurotrophic factors, which are potent regulators of neuronal development and function, have recently been implicated in the control of energy balance by increasing energy expenditure. We previously identified neudesin as a novel neurotrophic...
Kazuhiro Sakamoto, Tatsuya Okahashi, Shigenobu Matsumura, Yoko Okafuji, Shin Ichi Adachi, Satoshi Tsuzuki, Kazuo Inoue, Tohru Fushiki
Bioscience, Biotechnology and Biochemistry   79 658-663   Jan 2015   [Refereed]
© 2014 Japan Society for Bioscience, Biotechnology, and Agrochemistry. Rodents show a stronger preference for fat than sucrose, even if their diet is isocaloric. This implies that the preference mechanisms for fat and sucrose differ. To compare th...
Kazuhiro Sakamoto, Shigenobu Matsumura, Yoko Okafuji, Ai Eguchi, Takeshi Yoneda, Takafumi Mizushige, Satoshi Tsuzuki, Kazuo Inoue, Tohru Fushiki
Physiology and Behavior   138 227-235   Jan 2015   [Refereed]
© 2014 Elsevier Inc. The opioid system plays an important role in ingestive behavior, especially with regard to palatable high-fat or sweetened foods. In the present study, we investigated the role of the opioid system in the regulation of ingesti...
Takahiko Amitsuka, Maya Okamura, Hiroko Shiibashi, Naoto Yamamoto, Tsukasa Saito, Takashi Nammoku, Satoshi Tsuzuki, Kazuo Inoue, Tohru Fushiki
Journal of Nutritional Science and Vitaminology   60 328-333   Jan 2015   [Refereed]
© 2014, Center for Academic Publications Japan. Japanese cuisine has provided satisfying meals by fully utilizing the characteristic aroma and taste of katsuodashi (dried bonito broth), though it is not rich in sugars or fats. Katsuodashi is a ver...
Lee S, Eguchi A, Tsuzuki S, Matsumura S, Inoue K, Iwanaga T, Masuda D, Yamashita S, Fushiki T
PloS one   10(7) e0133412   2015   [Refereed]
Sakamoto K, Matsumura S, Okafuji Y, Eguchi A, Lee S, Adachi S, Fujitani M, Tsuzuki S, Inoue K, Fushiki T
Journal of nutritional science and vitaminology   61(3) 247-254   2015   [Refereed]
Lee S, Eguchi A, Sakamoto K, Matsumura S, Tsuzuki S, Inoue K, Masuda D, Yamashita S, Fushiki T
Biomedical research (Tokyo, Japan)   36(5) 303-311   2015   [Refereed]
Hiroyuki Ariyasu, Hiroyuki Ariyasu, Go Yamada, Go Yamada, Hiroshi Iwakura, Hiroshi Iwakura, Sigenobu Matsumura, Kazuo Inoue, Kenji Kangawa, Kazuwa Nakao, Kazuwa Nakao, Takashi Akamizu
Endocrine Journal   61 1041-1052   Jan 2014   [Refereed]
© The Japan Endocrine Society. Ghrelin has a potent orexigenic effect and induces adiposity when administered exogenously. Since plasma ghrelin levels rise before meals, ghrelin was thought to play a crucial role in the regulation of appetite. In ...
Shin Ichi Adachi, Ai Eguchi, Kazuhiro Sakamoto, Hiroki Asano, Yasuko Manabe, Shigenobu Matsumura, Satoshi Tsuzuki, Kazuo Inoue, Tohru Fushiki
Biomedical Research (Japan)   35 357-367   Jan 2014   [Refereed]
© 2014, Biomedical Research Foundation. All rights reserved. We recently reported that G-protein-coupled receptor 120 (GPR120) is expressed on taste buds, and that rodents showed preference for long-chain fatty acids (LCFA) at a low concentration....
Marie Takai, Yuki Kozai, Satoshi Tsuzuki, Yukari Matsuno, Maiko Fujioka, Kozue Kamei, Hitomi Inagaki, Ai Eguchi, Shigenobu Matsumura, Kazuo Inoue, Tohru Fushiki
Bioscience, biotechnology, and biochemistry   78 238-244   Jan 2014   [Refereed]
Transmembrane protein CD36 binds multiple ligands, including oxidized low-density lipoproteins (oxLDLs) and long-chain fatty acids (LCFAs). Our aim was to determine whether LCFAs compete with oxLDLs for binding to CD36. We addressed this issue by ...
Yuki Kozai, Satoshi Tsuzuki, Marie Takai, Ai Eguchi, Shigenobu Matsumura, Kazuo Inoue, Tohru Fushiki
Bioscience, biotechnology, and biochemistry   78 839-842   Jan 2014   [Refereed]
We recently obtained evidence that unsaturated long-chain fatty acids (LCFAs) (e.g. oleic acid) inhibit binding of oxidized low-density lipoproteins (oxLDLs) to CD36. In the present study, we validated this prediction by examining inhibition by un...
Y. Hiraoka; T. Matsuoka; M. Ohno; K. Nakamura; S. Saijo; S. Matsumura; K. Nishi; J. Sakamoto; P.-M. Chen; K. Inoue; T. Fushiki; T. Kita; T. Kimura; E. Nishi
Nature Communications   5    2014   [Refereed]
Fujitani M, Matsumura S, Masuda D, Yamashita S, Fushiki T, Inoue K
Bioscience, biotechnology, and biochemistry   78(11) 1871-1878   2014   [Refereed]
Amitsuka T, Okamura M, Shiibashi H, Yamamoto N, Saito T, Nammoku T, Tsuzuki S, Inoue K, Fushiki T
Journal of nutritional science and vitaminology   60(5) 328-333   2014   [Refereed]
Takahiro Horie, Takahiro Horie, Tomohiro Nishino, Osamu Baba, Yasuhide Kuwabara, Tetsushi Nakao, Masataka Nishiga, Shunsuke Usami, Masayasu Izuhara, Naoya Sowa, Naoya Yahagi, Hitoshi Shimano, Shigenobu Matsumura, Kazuo Inoue, Hiroyuki Marusawa, Tomoyuki Nakamura, Koji Hasegawa, Noriaki Kume, Masayuki Yokode, Toru Kita, Takeshi Kimura, Koh Ono
Nature Communications   4    Dec 2013   [Refereed]
MicroRNAs (miRs) are small non-protein-coding RNAs that bind to specific mRNAs and inhibit translation or promote mRNA degradation. Recent reports have indicated that miR-33, which is located within the intron of sterol regulatory element-binding ...
Kazuo Inoue
Advances in Neuroimmune Biology   4 229-236   Jan 2013
Central fatigue, which is manifested as a feeling of fatigue, is regarded as a kind of biological signal to alert that the ongoing behavior could be hazardous if it is continued. Several mechanisms in the brain that trigger central fatigue have be...
S. Tsuzuki; M. Takai; Y. Matsuno; Y. Kozai; M. Fujioka; K. Kamei; H. Inagaki; A. Eguchi; S. Matsumura; K. Inoue; T. Fushiki
Bioscience, Biotechnology and Biochemistry   77(1) 132-137   2013   [Refereed]
N. Mori; M. Kurata; H. Yamazaki; H. Hosokawa; T. Nadamoto; K. Inoue; T. Fushiki
Journal of Nutritional Science and Vitaminology   59(1) 56-63   2013   [Refereed]
M. Takai; S. Tsuzuki; Y. Matsuno; Y. Kozai; A. Eguchi; S. Matsumura; K. Inoue; T. Fushiki
Bioscience, Biotechnology and Biochemistry   77(5) 1134-1137   2013   [Refereed]
S.-I. Adachi; Y. Endo; T. Mizushige; S. Tsuzuki; S. Matsumura; K. Inoue; T. Fushiki
Bioscience, Biotechnology and Biochemistry   77(11) 2175-2180   2013   [Refereed]
S. Matsumura; A. Eguchi; Y. Okafuji; S. Tatsu; T. Mizushige; S. Tsuzuki; K. Inoue; T. Fushiki
FEBS Letters   586(8) 1231-1235   2012   [Refereed]
K. Kuramoto; T. Okamura; T. Yamaguchi; T.Y. Nakamura; S. Wakabayashi; H. Morinaga; M. Nomura; T. Yanase; K. Otsu; N. Usuda; S. Matsumura; K. Inoue; T. Fushiki; Y. Kojima; T. Hashimoto; F. Sakai; F. Hirose; T. Osumi
Journal of Biological Chemistry   287(28) 23852-23863   2012   [Refereed]
H. Yamada; Y. Iwaki; R. Kitaoka; M. Fujitani; T. Shibakusa; T. Fujikawa; S. Matsumura; T. Fushiki; K. Inoue
Journal of Nutritional Science and Vitaminology   58(2) 88-95   2012   [Refereed]
N. Mori; F. Kawabata; S. Matsumura; H. Hosokawa; S. Kobayashi; K. Inoue; T. Fushiki
American Journal of Physiology - Regulatory Integrative and Comparative Physiology   300(6) 1494-1505   2011   [Refereed]
T. Miyaki; T. Fujikawa; R. Kitaoka; N. Hirano; S. Matsumura; T. Fushiki; K. Inoue
Neuroscience   190 239-250   2011   [Refereed]
T. Fujikawa; R. Fujita; Y. Iwaki; S. Matsumura; T. Fushiki; K. Inoue
Physiology and Behavior   101(3) 370-375   Oct 2010   [Refereed]
S. Matsumura; A. Eguchi; N. Kitabayashi; M. Tanida; J. Shen; Y. Horii; K. Nagai; S. Tsuzuki; K. Inoue; T. Fushiki
Neuroscience Research   67(3) 236-244   Jul 2010   [Refereed]
R. Kitaoka; T. Fujikawa; T. Miyaki; S. Matsumura; T. Fushiki; K. Inoue
Journal of Nutritional Science and Vitaminology   56(3) 185-190   Jun 2010   [Refereed]
S. Matsumura; T. Yoneda; S. Aki; A. Eguchi; Y. Manabe; S. Tsuzuki; K. Inoue; T. Fushiki
Physiology and Behavior   99(4) 509-514   Mar 2010   [Refereed]
F. Kawabata; N. Inoue; Y. Masamoto; S. Matsumura; W. Kimura; M. Kadowaki; T. Higashi; M. Tominaga; K. Inoue; T. Fushiki
Bioscience, Biotechnology and Biochemistry   73(12) 2690-2697   Dec 2009   [Refereed]
Y. Fukatsu; T. Noguchi; T. Hosooka; T. Ogura; K. Kotani; T. Abe; T. Shibakusa; K. Inoue; M. Sakai; K. Tobimatsu; K. Inagaki; T. Yoshioka; M. Matsuo; J. Nakae; Y. Matsuki; R. Hiramatsu; K. Kaku; H. Okamura; T. Fushiki; M. Kasuga
Endocrinology   150(6) 2683-2691   Jun 2009   [Refereed]


From Bedside to Lab,from Lab to Bedside 救急医学研究を発展させるために 「もし大学病院の救急医が基礎研究をやったら」 臨床的視点からの基礎研究の重要性
苛原 隆之, 佐藤 格夫, 大嶽 康介, 邑田 悟, 井上 和生, 小池 薫, 横田 裕行
日本救急医学会雑誌   27(9) 349-349   Sep 2016
侵襲時の生体反応を改善する新しい試み 基礎研究 侵襲時の栄養代謝動態の変化と早期運動介入の効果
苛原 隆之, 佐藤 格夫, 大嶽 康介, 邑田 悟, 播摩 裕, 柚木 知之, 石原 健吾, 伏木 亨, 井上 和生, 横田 裕行, 小池 薫
外科と代謝・栄養   50(3) 153-153   Jun 2016
栄養生命科学のカッティング・エッジ 栄養/運動に対する中枢神経性調節を探る
井上 和生
日本栄養・食糧学会大会講演要旨集   70回 141-141   Apr 2016
権藤 大平, 李 信恵, 松村 成暢, 井上 和生, 伏木 亨
日本栄養・食糧学会大会講演要旨集   70回 217-217   Apr 2016
井本 優衣, 井上 和生, 横山 小夜香, 石井 仁, 高谷 亮典
日本栄養・食糧学会大会講演要旨集   70回 219-219   Apr 2016

Books etc

Exercise Fatigue.
Inoue K and Fushiki T.
Fatigue Science for Human Health, edited by Watanabe Y, Evengard B, Natelson BH, Jason LA and Kuratsune H. Tokyo: Springer, 2008, p. 187-202.   2008   
Effect of diet composition, physical training and physical inactivity on insulin sensitivity and insulin responsiveness.
井上 和生
Japan Scientific Societies Press,   1991   
Microdetermination of folate monoglutamates in serum by high-performance liquid chromatography with electrochemical detection
井上 和生
Walter de Gruyter & Co.,   1986   

Conference Activities & Talks

Exploration of the role of central regulation on nutrition/exercise physiology [Invited]
70th Annual Meeting of the Japan Society of Nutrition and Food Science   14 May 2016   
Exercise, fatigue and activation of TGF-beta in the brain. [Invited]
第33回 日本分子生物学会年会 第83回 日本生化学会大会 合同大会   2010   

Research Grants & Projects

Studies on the mechanisms of the generation of central fatigue