We investigate the normal selfenergy and the mass enhancement factor in the Hubbard model on the two-dimensional square lattice. Our purpose in this paper is to evaluate the mass enhancement factor more quantitatively than the conventional third order perturbation theory. We calculate it by expanding perturbatively up to the fourth order with respect to the on-site repulsion U. We consider the cases that the system is near the half-filling, which are similar situations to high-T-c cuprates. As results of the calculations, we obtain the large mass enhancement on the Fermi surface by introducing the fourth order terms. This is mainly originated from the fourth order particle-hole and particle-particle diagrams. Although the other fourth order terms have effect of reducing the effective mass, this effect does not cancel out the former mass enhancement completely and there remains still a large mass enhancement effect. In addition, we find that the mass enhancement factor becomes large with increasing the on-site repulsion U and the density of state (DOS) at the Fermi energy rho(O). According to many current reseaches, such large U and rho(O) enhance the effective interaction between quasiparticles, therefore the superconducting transition temperature T-c increases. On the other hand, the large mass enhancement leads the reduction of the energy scale of quasiparticles, as a result, T-c is reduced. When we discuss T-c, we have to estimate these two competitive effects.