Jun Kosaka

Profile Information

Affiliation: Professor, School of Medicine, Department of Anatomy, International University of Health and Welfare

Degree: Doctor of Science(The Graduate University for Advanced Studies)

J-GLOBAL ID: 200901094033829305
researchmap Member ID: 1000029547

External link: http://square.umin.ac.jp/oka-anat/kosaka

Research Interests

Research Areas

Research History

Apr, 2018 - Present

Professor, Graduate School of Medicine, International University of Health and Welfare
Apr, 2017 - Present

Professor, School of Medicine, International University of Health and Welfare
Apr, 2015 - Mar, 2017

Dean and Professor, Center for Medical Science, International University of Health and Welfare
Apr, 2014 - Mar, 2015

Professor, Center for Medical Science, International University of Health and Welfare
2007 - Mar, 2014

- 岡山大学医歯薬学総合研究科生体制御科学専攻准教授
2001 - 2007

岡山大学医歯薬学総合研究科助教授
2001 - 2007

Associate Professor,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
2007

- Associate Professor,Biophysiological Sciences,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
1998 - 2000

Medical School, Okayama University
1998 - 2000

Lecturer,Medical School,Okayama University
1992 - 1998

Osaka University
1992 - 1998

Research Associate,1992-1998 Osaka University Medical School, Research Associate

Education

- 1992

School of Life Science, The Graduate University for Advanced Studies
- 1992

Graduate School, Division of Life Science, The Graduate University for Advanced Studies
- 1988

Kanazawa University
- 1988

Faculty of Medicine, Kanazawa University

Committee Memberships

2017 - Present

代議員, 日本解剖学会
1997 - 2012

正会員, 神経組織の成長・再生・移植研究会
2011

正会員, 日本リンパ学会
2010

正会員, 日本形成外科学会
2007

regular member, The American Physiological Society
1999

正会員, 日本眼科学会
1998

評議員, 日本生理学会
1998

正会員, 日本発生生物学会
1998

正会員, 日本解剖学会
1997

Regular Member, The Association for Research in Vision and Ophthalmology
1996

正会員, 日本神経科学会
1996

Regular member, Society for Neuroscience
1994

正会員, 日本分子生物学会

Papers

A novel categorization of the muscular branches of the tibial nerve within the popliteal fossa

Takaya Ishii, Kyutaro Kawagishi, Shogo Hayashi, Shinnosuke Yamada, Hirotaka Yoshioka, Yoshiharu Matsuno, Yasutake Mori, Jun Kosaka

Annals of Anatomy - Anatomischer Anzeiger, 245 151997-151997, Jan, 2023
Effect of preconditioning on propofol-induced neurotoxicity during the developmental period

Satoshi Shibuta, Tomotaka Morita, Jun Kosaka

PLOS ONE, 17(8) e0273219-e0273219, Aug 19, 2022
A bilateral third head of the gastrocnemius which is morphologically similar to the plantaris

Takaya Ishii, Kyutaro Kawagishi, Shogo Hayashi, Shinnosuke Yamada, Hirotaka Yoshioka, Yoshiharu Matsuno, Yasutake Mori, Jun Kosaka

Surgical and Radiologic Anatomy, 43(7) 1095-1098, Jul, 2021
プロポフォールプレコンディショニングによる幼若神経細胞傷害への保護効果について

森田知孝, 澁田達史, 小阪淳

日本神経麻酔集中治療学会プログラム・抄録集, 25回 19-19, Jun, 2021
Intravenous anesthetic-induced calcium dysregulation and neurotoxic shift with age during development in primary cultured neurons.

Shibuta S, Morita T, Kosaka J

Neurotoxicology, Aug, 2018 Peer-reviewed
Enhancement of Lymphatic Vessels in the Superficial Layer in a Rat Model of a Lymphedematous Response.

Matsumoto K, Kosaka J, Suami H, Kimata Y

Plastic and reconstructive surgery. Global open, 6(5) e1770, May, 2018 Peer-reviewed
Positive association between the cross-sectional area of the rhomboid muscle, and the range of shoulder abduction after neck dissection surgery.

Ishii T, Hara T, Kusano S, Miura K, Kubo A, Kosaka J

Physical Therapy Research, 21(2) 39-43, 2018 Peer-reviewed
The studies of in vivo distributions of radioiodinated Cobalt-bleomycin in tumor-bearing animals by the whole body autoradiography.

Ando A, Ando I, Suda H, Nishimoto K, Kamei S, Kosaka J, Nishiyama Y, Yamamoto Y, Kuroda M, Kanazawa S

Radioisotopes, 66(8) 307-310, 2017 Peer-reviewed
Responses of Korean physical therapy students after practice with a virtual anatomical system in Japan

Heonsoo Han, Jun Kosaka, Seung-Chul Chon, Masafumi Itokazu, Akira Kubo

Journal of Physical Therapy Science, 29(10) 1749-1752, 2017 Peer-reviewed
Thiopental sodium preserves the responsiveness to glutamate but not acetylcholine in rat primary cultured neurons exposed to hypoxia

Tomotaka Morita, Satoshi Shibuta, Jun Kosaka, Yuji Fujino

JOURNAL OF THE NEUROLOGICAL SCIENCES, 365 126-131, Jun, 2016 Peer-reviewed
Enhancement of Motivation of Undergraduate Paramedical Students to Study Anatomy by a Novel Virtual Anatomy Training System

ITOKAZU Masafumi, KUBO Akira, TANIGUCHI Takamichi, KOSAKA Jun

Rigakuryoho Kagaku, 31(5) 715-717, Jan 1, 2016
Comparative morphology and development of extra-ocular muscles in the lamprey and gnathostomes reveal the ancestral state and developmental patterns of the vertebrate head.

Suzuki DG, Fukumoto Y, Yoshimura M, Yamazaki Y, Kosaka J, Kuratani S, Wada H

Zoological letters, 2 10, 2016 Peer-reviewed
Only extra-high dose of ketamine affects L-glutamate-induced intracellular Ca2+ elevation and neurotoxicity

Satoshi Shibuta, Tomotaka Morita, Jun Kosaka, Takahiko Kamibayashi, Yuji Fujino

NEUROSCIENCE RESEARCH, 98 9-16, Sep, 2015 Peer-reviewed
Organization and Cellular Arrangement of Two Neurogenic Regions in the Adult Ferret ( Mustela putorius furo) Brain

Yasuharu Takamori, Taketoshi Wakabayashi, Tetsuji Mori, Jun Kosaka, Hisao Yamada

JOURNAL OF COMPARATIVE NEUROLOGY, 522(8) 1818-1838, Jun, 2014 Peer-reviewed
Vascularized peripheral nerve grafting promotes myelination of regrowing optic nerve

Seiji Komatsu, Taketoshi Wakabayashi, Kiyoshi Yamada, Kumiko Matsumoto, Yoshihiro Kimata, Jun Kosaka

NeuroReport, 24(10) 566-571, Jul 10, 2013 Peer-reviewed
Loss of Ahi1 affects early development by impairing BM88/Cend1-mediated neuronal differentiation

Ling Weng, Yung-Feng Lin, Alina L. Li, Chuan-En Wang, Sen Yan, Miao Sun, Marta A. Gaertig, Naureen Mitha, Jun Kosaka, Taketoshi Wakabayashi …

Journal of Neuroscience, 33(19) 8172-8184, 2013 Peer-reviewed
Prolonged Expression of Puma in Cholinergic Amacrine Cells During the Development of Rat Retina

Taketoshi Wakabayashi, Jun Kosaka, Tetsuji Mori, Hisao Yamada

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 60(10) 777-788, Oct, 2012 Peer-reviewed
C38, equivalent to BM88, is developmentally expressed in maturing retinal neurons and enhances neuronal maturation

Taketoshi Wakabayashi, Jun Kosaka, Makoto Mochii, Yukari Miki, Tetsuji Mori, Yasuharu Takamori, Hisao Yamada

JOURNAL OF NEUROCHEMISTRY, 112(5) 1235-1248, Mar, 2010 Peer-reviewed
Acetylcholine induces Ca2+ signaling in chicken retinal pigmented epithelial cells during dedifferentiation

Mariko Sekiguchi-Tonosaki, Masakatsu Obata, Akira Haruki, Toshiyuki Himi, Jun Kosaka

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 296(5) C1195-C1206, May, 2009 Peer-reviewed
Intracellular delivery of proteins into mammalian living cells by polyethylenimine-cationization

J Futami, M Kitazoe, T Maeda, E Nukui, M Sakaguchi, J Kosaka, M Miyazaki, M Kosaka, H Tada, M Seno …

JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 99(2) 95-103, Feb, 2005 Peer-reviewed

Misc.

Responses of Korean physical therapy students after practice with a virtual anatomical system in Japan.

Heonsoo Han, Jun Kosaka, Seung-Chul Chon, Masafumi Itokazu, Akira Kubo

Rigakuryoho Kagaku (in Japanese), 32(Special3) 15, Mar, 2017
解剖学演習におけるバーチャル教材の有用性の検討

糸数昌史, 久保晃, 下井俊典, 本澤薫, 小阪淳

理学療法科学, 31 24, Jan 24, 2016
Architecture and cellular composition of two neurogenic regions in the adult ferret brain

Yasuharu Takamori, Taketoshi Wakabayashi, Tetsuji Mori, Kotaro Kitaya, Jun Kosaka, Hisao Yamada

NEUROSCIENCE RESEARCH, 68 E365-E365, 2010
Histochemical analysis of two neurogenic regions in the adult ferret brain

Yasuharu Takamori, Taketoshi Wakabayashi, Tetsuji Mori, Kotaro Kitaya, Jun Kosaka, Hisao Yamada

NEUROSCIENCE RESEARCH, 65 S102-S102, 2009
Doublecortin expression continues into adulthood in horizontal cells in the rat retina

Taketoshi Wakabayashi, Jun Kosaka, Tetsuji Mori, Yasuharu Takamori, Hisao Yamada

Neuroscience Letters, 442(3) 249-252, Sep, 2008
Responses to acetylcholine in the chicken retinal-pigmented epithelial cells during their dedifferentiation

Mariko Sekiguchi-Tonosaki, Masakatsu Obata, Akira Haruki, Junzo Sasaki, Toshiyuki Himi, Jun Kosaka

NEUROSCIENCE RESEARCH, 61 S228-S228, 2008
Early downregulation of IGF-I decides the fate of rat retinal ganglion cells after optic nerve injury

Keiko Homma, Yoshiki Koriyama, Kazuhiro Mawatari, Yoshihiro Higuchi, Jun Kosaka, Satoru Kato

NEUROCHEMISTRY INTERNATIONAL, 50(5) 741-748, Apr, 2007
C38 enhances neuronal maturation of P19 embryonal carcinoma cells

Taketoshi Wakabayashi, Tetsuji Mori, Yasuharu Takamori, Jun Kosaka, Yukari Miki, Hisao Yamada

NEUROSCIENCE RESEARCH, 58 S155-S155, 2007
Iris movement mediates vascular apoptosis during rat pupillary membrane regression

Y Morizane, S Mohri, J Kosaka, S Tone, T Kiyooka, T Miyasaka, J Shimizu, Y Ogasawara, F Shiraga, Y Minatogawa …

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 290(3) R819-R825, Mar, 2006
Retinal stem/progenitor properties of iris pigment epithelial cells

GW Sun, M Asami, H Ohta, J Kosaka, M Kosaka

DEVELOPMENTAL BIOLOGY, 289(1) 243-252, Jan, 2006
Quantification of PERF 15 mRNA in tissue sections from rat testes

Takashi Kogami, Yukari Miki, Teruo Yamada, Teruo Umegaki, Makoto Nishimura, Takashi Amo, Jun Kosaka, Junzo Sasaki

ACTA HISTOCHEMICA ET CYTOCHEMICA, 39(6) 183-192, 2006
JNK inhibitory kinase is up-regulated in retinal ganglion cells after axotomy and enhances BimEL expression level in neuronal cells

T Wakabayashi, J Kosaka, T Oshika

JOURNAL OF NEUROCHEMISTRY, 95(2) 526-536, Oct, 2005
Intracellular delivery of proteins into mammalian living cells by polyethylenimine-cationization

Junichiro Futami, Midori Kitazoe, Takashi Maeda, Emiko Nukui, Masakiyo Sakaguchi, Jun Kosaka, Masahiro Miyazaki, Megumi Kosaka, Hiroko Tada, Masaharu Seno …

Journal of Bioscience and Bioengineering, 99(2) 95-103, 2005
Quantification of in situ hybridization signals in rat testes

T Kimura, J Kosaka, T Nomura, T Yamada, Y Miki, K Takagi, T Kogami, J Sasaki

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 52(6) 813-820, Jun, 2004
Up-regulation of Hrk, a regulator of cell death, in retinal ganglion cells of axotomized rat retina

Taketoshi Wakabayashi, Jun Kosaka, Sachiko Hommura

Neuroscience Letters, 318(2) 77-80, Jan, 2002
Localization of mRNAs for trkB isoforms and p75 in rat retinal ganglion cells (vol 54, pg 27, 1998)

A Suzuki, S Nomura, E Morii, Y Fukuda, J Kosaka

JOURNAL OF NEUROSCIENCE RESEARCH, 55(1) 135-135, Jan, 1999
Differential localization and expression of α and β isoenzymes of protein kinase C in the rat retina

Jun Kosaka, Akira Suzuki, Eiichi Morii, Shintaro Nomura

Journal of Neuroscience Research, 54(5) 655-663, Dec 1, 1998
Localization of mRNAs for trkB isoforms and p75 in rat retinal ganglion cells

Akira Suzuki, Shintaro Nomura, Eiichi Morii, Yutaka Fukuda, Jun Kosaka

Journal of Neuroscience Research, 54(1) 27-37, Oct 1, 1998
Localization of mRNAs for trkB isoforms and p75 in rat retinal ganglion cells

Akira Suzuki, Shintaro Nomura, Eiichi Morii, Yutaka Fukuda, Jun Kosaka

Journal of Neuroscience Research, 54(1) 27-37, Oct 1, 1998
Thiopental sodium attenuates NO-induced neuronal death in primary brain culture

SHIBUTA S., KOSAKA J., FUKUDA Y., MASHIMO T., YOSHIYA I.

10(1) 99-100, Jun 6, 1998

Books and Other Publications

Presentations

脱分化誘導過程における網膜色素上皮細胞のアセチルコリンに対する応答性

第31回日本神経科学大会Neuro2008, 2008
網膜神経細胞の成熟を制御する分子の解析－シンポジウム「網膜を材料にした多角的アプローチにより組織細胞の姿を知る」

第114回日本解剖学会総会, 2008
C38 enhances neuronal maturation of P19 embryonal carcinoma cells

第30回日本神経科学大会・第50回日本神経化学会大会・合同年会, 2007
モノクローナル抗体C38が認識する抗原の網膜発生における発現の変化

第112回日本解剖学会総会, 2007
色素上皮細胞の脱分化に伴う生理機能変化

第112回日本解剖学会総会, 2007
JIKは視神経切断後に網膜神経節細胞で発現誘導されBimELの発現を制御する

第110回日本眼科学会総会, 2006
JIKは視神経切断後に網膜神経節細胞で発現誘導されBimELの発現を誘導する

第28回日本分子生物学会, 2005
正常発生における血管網のアポトーシスにも血流の生理的変化が関与する

第110回日本解剖学会総会, 2005
Trials to detect the pivotal factor that induces cell death of retinal ganglion cells after axotomy

16th International Congress of the International Federation of Associations of Anatomists, Evening Session Symposium., 2004
"Survival and axonal regeneration of retinal ganglion cells in peripheral nerve-grafted mammals" in Symposium: Current Topics in Cell Biology”

The 6th Jappan-China Joint Seminar on Histochemistry and Cytochemistry., 2001
免疫抑制剤を使用した細胞種特的な抗体作成の効率化

第１０４回日本解剖学会総会、テクニカルワークショップ「免疫組織化学」, 2001

Teaching Experience

Professional Memberships

Works

Research Projects

Effects of exercise in the strctures of lymphatic networks in secondary lymphedema: an analysis using a rat model.

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2020 - Mar, 2023
Vascularized peripheral nerve graft and recovery of visual function

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2019

WAKABAYASHI Taketoshi, HIRAHARA Yukie
再生視神経回路のリハビリテーションによる視覚中枢の遺伝子発現パターン修飾

科学研究費補助金, 日本学術振興会, 2015 - 2017

小阪淳
Inhibition of RPE senescence by AMPK activation

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015

YUKI Morizane, KOSAKA Jun, YONEZAWA Tomoko
The onset mechanism of neurodegenerative diseases caused by mutation in the genes encoding lamins and nuclear lamina associated proteins.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015

TAKAMORI Yasuharu, YAMADA Hisao, WAKABAYASHI Taketoshi, MORI Tetsuji, WADA Yukie, KUROKAWA Kiyoshi, KOSAKA Jun, KOIKE Taro
The neuroprotective effects of anesthetics against hypoxia

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2011 - Mar, 2015

SHIBUTA Satoshi, KAMIBAYASHI Takahiko, MIYAMOTO Yoshikazu, KOSAKA Jun
regeneration of lymph duct in rat lymphedema model

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2014

MATSUMOTO Kumiko, KOSAKA Jun, KIMATA Yoshihiro, SUAMI Hiroo
2本の血管柄付き末梢神経移植による網膜－視覚中枢投射の再構築

科学研究費補助金, 日本学術振興会, 2012 - 2014

小阪淳
Demonstrating thelymphatic system with microinjection during its regeneration process

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2010 - 2012

KIMATA Yoshihiro, YAMADA Kiyoshi, KOSAKA Jun, SUAMI Hiroo, MATSUMOTO Kumiko
マイクロサージェリーを駆使した新しい中枢神経軸索再生法の確立と分子生物学的評価

科学研究費補助金, 日本学術振興会, 2009 - 2011

小阪淳
Analysis of axonal regeneration of retinal ganglion cells after vascularized peripheral nerve graft.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2008 - 2010

WAKABAYASHI Taketoshi, KOSAKA Jun, MORI Tetsuji, KIMATA Takahiro, YAMASHITA Syuji
網膜神経節細胞の分子多様性の解明による細胞死阻止の研究

科学研究費補助金, 日本学術振興会, 2007 - 2008

小阪淳
Molecular mechanism of subtype specific death of retinal ganglion cells induced by different stimuli.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2006 - 2007

WAKABAYASHI Taketoshi, KOSAKA Jun
Quantification of transcripts in testes preparation and its application to other tissue sections

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2006 - 2007

SASAKI Junzo, MIKI Yukari, YAMADA Teruo, KOSAKA Jun, FUJITA Hirofumi
Analysis of gene expression in the rat testis during exposure to endocrine-disrupting chemicals

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2003 - 2004

SASAKI Junzo, NOMURA Takako, YAMADA Teruo, KOSAKA Jun
Research of gene expression during rat spermatogenesis and the role of reactive oxygen species in rat testis under the physiological and pathological conditions

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2002 - 2003

NOMURA Takako, SASAKI Junzo, KOSAKA Jun, YAMADA Teruo
Basic research to achieve reconstitution of optic tract and the retinotopic projection

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2001 - 2003

KOSAKA Jun
How reactive oxygen species mediate the effects of endocrine-disrupting agents on the reproductive organs?

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2001 - 2002

SASAKI Junzo, KOSAKA Jun, YAMADA Teruo, NOMURA Takako
内分泌かく乱物質が生殖器に及ぼす作用機構の解析

科学研究費助成事業, 特定領域研究(A), 日本学術振興会, 2001 - 2001

佐々木順造, 小阪淳, 山田輝夫, 野村貴子
中枢神経細胞の生と死と再生を分ける分子機構の解析

科学研究費助成事業特定領域研究(C), 特定領域研究(C), 日本学術振興会, 2001 - 2001

小阪淳

Industrial Property Rights

特許4882071 基板、及び標的物質の定量方法

小阪淳, 佐々木順造

Profile Information

Research Interests

Research Areas

Research History

Education

Committee Memberships

Papers

Misc.

Books and Other Publications

Presentations

Teaching Experience

Professional Memberships

Works

Research Projects

Industrial Property Rights

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