Junichi Fujii - My portal

Profile Information

Affiliation: Professor, Graduate School of Medical Science Major of Environmental Life Science Department of Biochemistry and Molecular Biology, Yamagata University

J-GLOBAL ID: 200901084830911593
researchmap Member ID: 1000029551

External link

Research Interests

Research Areas

Research History

Jul, 1999 - Present

Professor, Graduate School of Medical Science Major of Environmental Life Science Department of Biochemistry and Molecular Biology, Yamagata University
1996 - 1999

Osaka University
1996 - 1999

Osaka University, Associate Professor
1993 - 1996

Osaka University
1993 - 1996

Assistant Professor Osaka University
1992 - 1993

Osaka University
1992 - 1993

Osaka University, Research Associate
1991 - 1992

学術振興会特別研究員(PD)
1991 - 1992

Japan. Society for the Promotion of Science,
1988 - 1991

University of Toronto
1988 - 1991

University of Toronto, Postdoctoral fellow
Postdoctoral fellow

Education

- Mar, 1988

Graduate School, Division of Medicine, Osaka University
- 1988

Graduate School, Division of Medicine, Osaka University
- Mar, 1984

Graduate School, Division of Bioresearch, Shizuoka University
- Mar, 1982

Faculty of Science, Shizuoka University
- 1982

Faculty of Science, Shizuoka University

Committee Memberships

2008 - Present

理事, 日本酸化ストレス学会
2001 - Present

評議員, 日本酸化ストレス学会
2000 - Present

評議員, 日本生化学会
2000 - Present

評議員, 日本NO学会
May, 2021 - May, 2021

第74回日本酸化ストレス学会学術集会会長, 日本酸化ストレス学会
2003

boardman:, Japanese Society of Lipid Peroxide and Free Radical Research,ˇ
2001

評議員, Society for Free Radical Research Japan
2001

boardman:, Societies for Free Radical Research,
2000

boardman:, NO Society of Japan,
1999

評議員, 日本生化学会
1999

boardman:, Japanese Biochemical Society,

Awards

Oct, 2020

2020年日本酸化ストレス学会学会賞, 日本酸化ストレス学会

藤井順逸

Papers

129

Nitric oxide produced by NOS2 copes with the cytotoxic effects of superoxide in macrophages.

Sho Kobayashi, Takujiro Homma, Junichi Fujii

Biochemistry and biophysics reports, 26 100942-100942, Jul, 2021 Peer-reviewed
Superoxide produced by mitochondrial complex III plays a pivotal role in the execution of ferroptosis induced by cysteine starvation

Takujiro Homma, Sho Kobayashi, Hideyo Sato, Junichi Fujii

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 700 108775, Mar 30, 2021 Peer-reviewed
Developmental retardation in neonates of aldehyde reductase (AKR1A)-deficient mice is associated with low ascorbic acid and high corticosterone levels.

Naoki Ishii, Takujiro Homma, Yuji Takeda, Naing Ye Aung, Ken-Ichi Yamada, Satoshi Miyata, Hironobu Asao, Mitsunori Yamakawa, Junichi Fujii

The Journal of nutritional biochemistry, 91 108604-108604, Feb 4, 2021 Peer-reviewed
Characterization of a rat monoclonal antibody raised against ferroptotic cells

Sho Kobayashi, Yumi Harada, Takujiro Homma, Chikako Yokoyama, Junichi Fujii

JOURNAL OF IMMUNOLOGICAL METHODS, 489 112912, Feb, 2021 Peer-reviewed
Defective biosynthesis of ascorbic acid in Sod1-deficient mice results in lethal damage to lung tissue.

Takujiro Homma, Yuji Takeda, Tomoyuki Nakano, Shinya Akatsuka, Daisuke Kinoshita, Toshihiro Kurahashi, Shinichi Saitoh, Ken-Ichi Yamada, Satoshi Miyata, Hironobu Asao …

Free radical biology & medicine, 162 255-265, Jan, 2021 Peer-reviewed
Testis-specific peroxiredoxin 4 variant is not absolutely required for spermatogenesis and fertility in mice.

Takujiro Homma, Toshihiro Kurahashi, Naoki Ishii, Nobuyuki Shirasawa, Junichi Fujii

Scientific reports, 10(1) 17934-17934, Oct 21, 2020 Peer-reviewed
Ascorbic acid prevents N-nitrosodiethylamine-induced hepatic injury and hepatocarcinogenesis in Akr1a-knockout mice.

Naoki Ishii, Takujiro Homma, Xin Guo, Ken-Ichi Yamada, Sohsuke Yamada, Junichi Fujii

Toxicology letters, 333 192-201, Oct 15, 2020 Peer-reviewed
Iron loading exerts synergistic action via a different mechanistic pathway from that of acetaminophen-induced hepatic injury in mice

Moon Gyul, Kobayashi Sho, Naing Ye Aung, Yamada Ken-ichi, Yamakawa Mitsunori, Fujii Junichi

FREE RADICAL RESEARCH, 54(8-9) 606-619, Sep 1, 2020 Peer-reviewed
Cysteine preservation confers resistance to glutathione-depleted cells against ferroptosis via CDGSH iron sulphur domain-containing proteins (CISDs).

Takujiro Homma, Sho Kobayashi, Junichi Fujii

Free radical research, 54(6) 397-407, Jun 2, 2020 Peer-reviewed
Genetic ablation of aldehyde reductase (Akr1a) augments exercise endurance in mice via activation of the PGC-1α-involved pathway.

Miku Takahashi, Takujiro Homma, Ken-Ichi Yamada, Satoshi Miyata, Osamu Nakajima, Junichi Fujii

Life sciences, 249 117501-117501, May 15, 2020 Peer-reviewed
γ-Glutamylcysteine synthetase and γ-glutamyl transferase as differential enzymatic sources of γ-glutamylpeptides in mice

Sho Kobayashi, Yoshitaka Ikeda, Yuhei Shigeno, Hiroyuki Konno, Junichi Fujii

Amino Acids, 52(4) 555-566, Apr, 2020 Peer-reviewed
Ascorbic acid and CoQ10 ameliorate the reproductive ability of superoxide dismutase 1-deficient female mice†.

Naoki Ishii, Takujiro Homma, Jaeyong Lee, Hikaru Mitsuhashi, Ken-Ichi Yamada, Naoko Kimura, Yorihiro Yamamoto, And Junichi Fujii

Biology of reproduction, 102(1) 102-115, Jan, 2020 Peer-reviewed
Heterozygous SOD1 deficiency in mice with an NZW background causes male infertility and an aberrant immune phenotype.

Takujiro Homma, Yuji Takeda, Satoshi Sakahara, Naoki Ishii, Sho Kobayashi, Hiroyuki Abe, Hironobu Asao, Junichi Fujii

Free radical research, 53(11-12) 1060-1072, Dec 2, 2019 Peer-reviewed
Edaravone, a free radical scavenger, protects against ferroptotic cell death in vitro.

Takujiro Homma, Sho Kobayashi, Hideyo Sato, Junichi Fujii

Experimental cell research, 384(1) 111592-111592, Nov 1, 2019 Peer-reviewed
Ascorbic acid insufficiency impairs spatial memory formation in juvenile AKR1A-knockout mice.

Kazuki Kurihara, Takujiro Homma, Sho Kobayashi, Mototada Shichiri, Hiroki Fujiwara, Satoshi Fujii, Ken-Ichi Yamada, Masaki Nakane, Kaneyuki Kawamae, Junichi Fujii

Journal of clinical biochemistry and nutrition, 65(3) 209-216, Nov 1, 2019 Peer-reviewed
Induction of ferroptosis by singlet oxygen generated from naphthalene endoperoxide.

Takujiro Homma, Sho Kobayashi, Junichi Fujii

Biochemical and biophysical research communications, 518(3) 519-525, Oct 20, 2019 Peer-reviewed
Oxidative stress triggers systemic organ disorders associated with impaired lipid catabolism in mice during fasting

Homma Takujiro, Lee Jaeyong, Kobayashi Sho, Ishii Naoki, Fujii Junichi

FREE RADICAL BIOLOGY AND MEDICINE, 139 S29-S29, Aug 1, 2019 Peer-reviewed
Oxidative stress triggers systemic organ disorders associated with impaired lipid catabolism in mice during fasting

Homma Takujiro, Lee Jaeyong, Kobayashi Sho, Ishii Naoki, Fujii Junichi

FREE RADICAL BIOLOGY AND MEDICINE, 139 S29-S29, Aug 1, 2019 Peer-reviewed
Oxidative stress triggers systemic organ disorders associated with impaired lipid catabolism in mice during fasting

Homma Takujiro, Lee Jaeyong, Kobayashi Sho, Ishii Naoki, Fujii Junichi

FREE RADICAL BIOLOGY AND MEDICINE, 139 S29-S29, Aug 1, 2019 Peer-reviewed
An SOD1 deficiency aggravates proteasome inhibitor bortezomib-induced testicular damage in mice.

Homma T, Fujii J

Biochimica et biophysica acta. General subjects, 1863(6) 1108-1115, Jun, 2019 Peer-reviewed

Misc.

109

Erythrocytes as a preferential target of oxidative stress in blood.

Junichi Fujii, Takujiro Homma, Sho Kobayashi, Prashant Warang, Manisha Madkaikar, Malay B Mukherjee

Free radical research, 55(5) 562-580, Jan 17, 2021 Peer-reviewedInvited
Ascorbate is a multifunctional micronutrient whose synthesis is lacking in primates.

Junichi Fujii

Journal of Clinical Biochemistry and Nutrition, 2021 Peer-reviewedInvited
Emerging connections between oxidative stress, defective proteolysis, and metabolic diseases.

Takujiro Homma, Junichi Fujii

Free radical research, 54(11-12) 931-946, Apr, 2020 Peer-reviewedInvited
Ferroptosis caused by cysteine insufficiency and oxidative insult.

Sep, 2019 Peer-reviewedInvited
Macrophages from xCT-deficient mice survive under low cysteine/glutathione redox conditions with high oxidative stress

Sho Kobayashi, Shinji Hamashima, Takujiro Homma, Junichi Fujii, Hideyo Sato

FREE RADICAL BIOLOGY AND MEDICINE, 108 S52-S52, Jul, 2017 Peer-reviewed
Roles of Antioxidative Enzymes in Wound Healing

Toshihiro Kurahashi, Junichi Fuji

J Dev Biol, 3(2) 57-70, 2015 Peer-reviewedInvited
Reactive Nitrogen Oxide Species in Red Blood Cells Are Possible Cause for Hemolytic Anemia and Autoimmunity in SOD1-Deficient Mice

Junichi Fujii, Yoshihito luchi, Satoshi Tsunoda, Noriko Kibe, Saori Suzuki, Futoshi Okada

NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 22 S60-S60, Jun, 2010
Prevention of tumor progression as the ultimate goal of cancer therapy

Futoshi Okada, Junichi Fujii

Cancer Therapy, 3 219--226, 2005 Peer-reviewedInvited
Carbonyl stress and detoxification ability in the male genital tract and testis of rats

Y Iuchi, T Kaneko, S Matsuki, T Ishii, Y Ikeda, K Uchida, J Fujii

HISTOCHEMISTRY AND CELL BIOLOGY, 121(2) 123-130, Feb, 2004
The accumulation of Mn-superoxide dismutase under metal-depleted conditions: An implicated role of zinc ion for cellular redox balance.

Kaoru Otsu, Yoshitaka Ikeda, Junichi Fujii

Biochem. J., 377 241-248, 2004 Peer-reviewed
Suppression of cytochrome c release and apoptosis in testes with heat stress by minocycline

S Matsuki, Y Iuchi, Y Ikeda, Sasagawa, I, Y Tomita, J Fujii

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 312(3) 843-849, Dec, 2003
Transient elevation of glutathione peroxidase 1 around the time of eyelid opening in the neonatal rat.

Tsuneko Fujii, Yoshitaka Ikeda, Hidetoshi Yamashita, Junichi Fujii

J. Ocul. Pharmacol. Ther., 19(4) 361-9, Aug, 2003 Peer-reviewed
Glycation proceeds faster in mutated Cu, Zn-superoxide dismutases related to familial amyotrophic lateral sclerosis.

Rina Takamiya, Motoko Takahashi, Theingi Myin, Yong Seek Park, Nobuko Miyazawa, Takeshi Endo, Noriko Fujiwara, Haruhiko Sakiyama, Yoshiko Misonou, Yasuhide Miyamoto …

FASEB J., 17(8) 938-40, May, 2003 Peer-reviewed
Colocalization of polyol-metabolizing enzymes and immunological detection of fructated proteins in the female reproductive system of the rat.

Tomoko Kaneko, Yoshihito Iuchi, Motoko Takahashi, Junichi Fujii

Histochem. Cell Biol., 119(4) 309-15, Apr, 2003 Peer-reviewed
Cooperative function of antioxidant and redox systems against oxidative stress in male reproductive tissues

Junichi Fujii, Yoshihito Iuchi, Shingo Matsuki, Tatsuya Ishii

Asian J. Androl., 5(3) 231-242, 2003 Peer-reviewedInvited
Concerted changes in the YB2/RYB-a protein and protamine 2 messenger RNA in the mouse testis under heat stress

Y Iuchi, T Kaneko, S Matsuki, Sasagawa, I, J Fujii

BIOLOGY OF REPRODUCTION, 68(1) 129-135, Jan, 2003
Differential expression of glutathione reductase and cytosolic glutathione peroxidase, GPX1, in developing rat lungs and kidneys

T Fujii, T Endo, J Fujii, N Taniguchi

FREE RADICAL RESEARCH, 36(10) 1041-1049, Oct, 2002
Expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione function in spermatogenesis.

Tomoko Kaneko, Yoshihito Iuchi, Takashi Kobayashi, Tsuneko Fujii, Hidekazu Saito, Hirohisa Kurachi, Junichi Fujii

Eur. J. Biochem., 269(5) 1570-8, Mar, 2002 Peer-reviewed
Impaired expression of peroxiredoxin 4 in damaged testes by artificial cryptorchidism.

Shingo Matsuki, Isoji Sasagawa, Yoshihito Iuchi, Junichi Fujii

Redox Rep., 7(5) 276-278, 2002 Peer-reviewedInvited
Advances in our understanding of peroxiredoxin, a multifunctional, mammalian redox protein

J Fujii, Y Ikeda

REDOX REPORT, 7(3) 123-130, 2002

Books and Other Publications

Ferroptosis in Health and Disease

Junichi Fujii, Sho Kobayashi, Takujiro Homma

Springer Nature, 2019
Glutathione and related compounds produced by the glutathione-synthesizing pathway

Junichi Fujii, Sho Kobayashi, Takujiro Homma (Role: Joint author)

Nova Science Publisher Inc, 2019
Oxidative stress and dysfunction of the intracellular proteolytic machinery: a pathological hallmark of nonalcoholic fatty liver disease

Takujiro Homma, Junichi Fujii (Role: Joint author)

Elsevier, 2019
ベインズ・ドミニチャク生化学

Baynes John W, Dominiczak Marek H, 谷口直之, 岩井一宏, 藤井順逸, 本家孝一

エルゼビア・ジャパン, 2018 (ISBN: 9784621301692)
Superoxide Dismutase (SOD): Sources, Therapeutic Uses and Health Benefits." (Nancy H. Phillips, ed.)

Takujiro Homma, Junichi Fujii (Role: Joint author, Chapter 2; Indispensable Roles of Superoxide Dismutation in Mammalian Erythrocytes. In "Superoxide Dismutase (SOD): Sources, Therapeutic Uses and Health Benefit)

Nova Science Publishers, Inc, 2016
Ascorbic Acid: Properties, Synthesis and Applications

Junichi Fujii, Takujiro Homma, Sho Kobayashi (Role: Joint author, Chapter 11: Ascorbic Acid as a Multifunctional Nutrient in Mammals; Our Understanding based on Studies using Genetically Modified Mice.)

Nova Science Publishers, Inc, 2016
Handbook of System Biology of Free Radicals and Anti-oxidants

Fujii J, Tsunoda S, Kimura N (Role: Joint author)

Springer-Verlag, 2014
Medical Biochemistry 4th ed

Junichi Fuji (Role: Joint author)

Elsevier, 2014
Male and Female Infertility: Genetic Causes, Hormonal Treatments and Health Effects.

Fujii J, Iuchi Y (Role: Joint author)

Nova Science Publishers, 2010
Male and Female Infertility: Genetic Causes, Hormonal Treatments and Health Effects.

Fujii J, Iuchi Y (Role: Joint author)

Nova Science Publishers, 2010
Medical Biochemistry 3rd ed

Junichi Fujii (Role: Joint author)

Elsevier, 2009
Medical Biochemistry 2nd ed

Junichi Fujii (Role: Joint author)

Mosby, 2005
The Maillard Reaction in Food Chemistry and Medical Science: Update for the Postgenomic Era

Junichi Fujii, Tomoko Kaneko, Takashi Kobayashi, Yoshihito Iuchi, Motoko Takahashi

Elsevier, 2002
Abnormal Glycation in ALS.(共著)

Molecular Mechanism and Therapeutics of Amyotrophic Lateral Sclerosis in Elsevier, 2001
Superoxide Dismutases in Exercise and Disease. (共著)

Handbook of Oxidants and Antioxidants in Exercise Elsevier Science, 2000
Handbook of Oxidants and Antioxidants in Exercise

K. Suzuki, H. Ohno, S. Oh-ishi, T. Kizaki, T. Ookawara, J. Fujii, Z. Radak, N. Taniguchi

Elsevier, 2000
Dysfunction of Redox System by Reactive Oxygen and Nitrogen Species. (共著)

Redox Regulation of Cell Signaling and Its Clinical Applications Marcel Dekker, 1999
Chapter 5. Catalytic Protein-Enzymes

Medical Biochemistry, Mosby, 1999
Physiological Relevance of Aldehyde Reductase and Aldose Reductase Gene Expression. (共著)

Enzymology and Molecular Biology of Carbonyl Metabolism, 1999
Redox Regulation of Cell Signaling and Its Clinical Applications

Junichi Fujii, Naoyuki Taniguchi (Role: Joint author)

Marcel Dekker, 1999

Presentations

マクロファージNOS2の生成するNOはスーパーオキシドの毒性消去に働く

マクロファージNOS, の生成するNOはスーパーオキシドの毒性消去に働く

第73回日本酸化ストレス学会・第20回日本NO学会合同学術集会
アスコルビン酸は遊離鉄の毒性を抑制することによりアセトアミノフェン肝障害を軽減する

藤井順逸, 文潔, 小林翔, 山田健一

第73回日本酸化ストレス学会・第20回日本NO学会合同学術集会
グルタチオン合成阻害環境下における鉄硫黄クラスター形成反応のフェロトーシス感受性への関与

本間拓二郎, 小林翔, 藤井順逸

第73回日本酸化ストレス学会・第20回日本NO学会合同学術集会
フェロトーシス細胞を認識するラットモノクローナル抗体の作製とその性質

小林翔, 原田裕未, 本間拓二郎, 横山智哉子, 藤井順逸

第93回日本生化学会大会
Prevention of diethylnitrosamine-induced hepatic injury and carcinogenesis in mice by vitamin C

Naoki Ishii, Takujiro Homma, Junichi Fujii

8th International Translational Cancer Research Conference:Role of Inflammation and Immune System for Cancer Prevention and Treatment Invited
Oxidative stress as the causal factor for anemic diseases.

The Society for Free Radical Research (SFRR)-INDIA-2020 Invited
Aldehyde reductase (Ak1a)ノックアウトマウスの発育障害ならびに発癌剤感受性に関する検討

石井直樹, 本間拓二郎, 小林翔, 藤井順逸

第92回日本生化学会大会
エダラボンをはじめとする各種フリーラジカル消去剤によるフェロトーシス抑制作用

本間拓二郎, 小林翔, 佐藤英世, 藤井順逸

第92回日本生化学会大会
LC-MSによるgグルタミルペプチド類の定量解析と生体内でのgグルタミルペプチド類の産生経路に関する研究

小林翔, 文潔, 本間拓二郎, 池田義孝, 今野博行, 藤井順逸

第92回日本生化学会大会
フリーラジカル消去剤エダラボンによるフェロトーシス抑制作用

本間拓二郎, 小林翔, 佐藤英世, 藤井順逸

第72回日本酸化ストレス学会
Cysteine-Glutathione Redox System Protective Against Ferroptosis

Junichi Fujii

Invited
Oxidative stress aggravates proteasome inhibitor bortezomib-induced proteotoxicity in mice

9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
Amelioration of the reproductive ability of SOD1-deficient female mice by supplemented ascorbic acid and CoQ10

9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
Carnosine dipeptidase 2 (CNDP2) as a potential survival factor for xCT-deficient cells against ferroptosis.

9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
Quantitative analysis of γ-glutamylpeptides by LC-MS and application for studying liver injury and γ-glutamyltransferase assay

9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
絶食したSOD1欠損マウスに蓄積する脂肪滴は臓器障害の原因とはならない

李在勇, 小林翔, 本間拓二郎, 藤井順逸

山形医学, Feb, 2019, 山形大学
アスコルビン酸合成能の欠損はマウスの運動能力を高める

高橋未来, 本間拓二郎, 石井直樹, 宮田哲, 中島修, 藤井順逸

山形医学, Feb, 2019, 山形大学
CoQ10とアスコルビン酸によるSOD1欠損雌マウスの生殖機能の改善

石井直樹, 本間拓二郎, 李在勇, 小林翔, 三橋輝, 木村直子, 山本順寛, 藤井順逸

山形医学, Feb, 2019, 山形大学
アスコルビン酸合成不全(Akr1a欠損)マウスは高い持久力を示す

高橋未来, 本間拓二郎, 石井直樹, 中島修, 藤井順逸

第41回日本分子生物学会大会
Oxidative stress triggers systemic organ disorders associated with impaired lipid catabolism in mice during fasting

Takujiro Homma, Jaeyong Lee, Toshihiro Kurahashi, Sho Kobayashi, Naoki Ishii, Junichi Fujii

第41回日本分子生物学会大会

Teaching Experience

Apr, 2022 - Mar, 2023

人体物質代謝学 (山形大学)
Apr, 2022 - Sep, 2022

医学を理解するための自然・社会科学（人間を考える） (山形大学)
Oct, 2021 - Mar, 2022

先端医科学特論 (山形大学)
Apr, 2021 - Sep, 2021

人体物質代謝学 (山形大学)
Oct, 2020 - Mar, 2021

先端医科学特論 (山形大学)
Apr, 2020 - Sep, 2020

人体物質代謝学 (山形大学)
Oct, 2019 - Mar, 2020

先端医科学特論 (山形大学)
Apr, 2019 - Sep, 2019

人体物質代謝学 (山形大学)
Apr, 2018 - Mar, 2019

人体物質代謝学 (山形大学)
生化学 (山形大学医学部)

Professional Memberships

Apr, 2001 - Present

日本酸化ストレス学会
Apr, 1992 - Present

日本癌学会
Apr, 1990 - Present

日本分子生物学会
Apr, 1982 - Present

日本生化学会
日本NO学会
Society for Free Radical Research Japan
Society for Free Radical Biology and Medicine&
Society for the Study of Reproduction
ˇ
Japanese Society of Lipid Peroxide and Free Radical Research
Societies for Free Radical Research
NO Society of Japan
American Society for Biochemistry and Molecular Biology
Japanese Cancer Association
Japanese Molecular Biological Society
Japanese Biophysical Society
Japanese Biochemical Society

Works

Involvement of Glycation in Alzheimer Disease

1998 - 2000
Mechanism of FACS onset by SOD1 mutation

1997 - 2000
Roles of Redox System in Spermatogenesis

1999

Research Projects

[大阪大学蛋白質研究所共同研究員]ジペプチダーゼCNDP2による酸化ストレスを起因とする新規細胞死・フェロトーシスからの保護機構の解明

Apr, 2021 - Mar, 2022
[大阪大学蛋白質研究所共同研究員]ジペプチダーゼCNDP2による酸化ストレスを起因とする新規細胞死・フェロトーシスからの保護機構の解明

Apr, 2020 - Mar, 2021
PPAR活性化による酸化ストレス・小胞体ストレス軽減による脂肪性肝疾患の改善

文部科学省, Apr, 2019 - Mar, 2021
Verification of reduction of superoxide toxicity by nitric oxide (NO) synthase and exogenous NO

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2021

Fujii Junichi
[大阪大学蛋白質研究所共同研究員]ジペプチダーゼCNDP2による酸化ストレスを起因とする新規細胞死・フェロトーシスからの保護機構の解明

Apr, 2019 - Mar, 2020
Japan-India collaborative research aspiring for conquering sickle cell disease by elucidating the developmental mechanism

Ministry of Education, Culture, Sports, Science and Technology, Jun, 2018 - Mar, 2020
[東北大学加齢医学研究所共同利用・共同研究]Nrf2により発現制御される抗酸化・レドックス遺伝子のアスコルビン酸欠乏下における役割の解明

Apr, 2018 - Mar, 2019
[大阪大学蛋白質研究所共同研究員]酸化ストレスによる赤血球蛋白質の酸化的修飾の解明

Apr, 2018 - Mar, 2019
リモデリングを司る細胞間基質の酸化障害と制御機構に関する日韓共同研究

文部科学省, Apr, 2017 - Mar, 2019
[大阪大学蛋白質研究所共同研究員]グルタチオン欠乏マクロファージの生存を可能とする因子のプロテオミクス解析による探索

Apr, 2017 - Mar, 2018
Japan-India collaborative research aspiring for prevention and diagnosis of erythrocyte-associated diseases

Ministry of Education, Culture, Sports, Science and Technology, Jun, 2016 - Mar, 2018
[大阪大学蛋白質研究所共同研究員]酸化ストレスによる赤血球蛋白質の酸化的修飾の解明

Apr, 2016 - Mar, 2017
[大阪大学蛋白質研究所共同研究員]レドックス分子Peroxiredoxin 4 (Prx4)のカルシウム制御と精巣における役割の解明

Apr, 2015 - Mar, 2016
[大阪大学蛋白質研究所共同研究員]タンパク質の酸化的折畳みにおけるレドックス分子Peroxiredoxin 4 (Prx4)の役割の解明

Mar, 2014 - Mar, 2015
蛋白質機能のレドックス制御機構を解明する若手研究者育成のための日欧共同研究

文部科学省, Oct, 2012 - Mar, 2015
[大阪大学蛋白質研究所共同研究員]タンパク質の酸化的折畳みにおけるレドックス分子 Peroxiredoxin 4 (Prx4)の役割の解明

Apr, 2013 - Mar, 2014
[大阪大学蛋白質研究所共同研究員]レドックス分子Peroxiredoxin 4 (Prx4)による活性酸素シグナルの制御機構の解明

Apr, 2012 - Mar, 2013
レドックス分子Perxoiredoxin 4（Prx4）による活性酸素シグナル制御機構の解明

Apr, 2011 - Mar, 2012
Research on Antioxidative Systems
Analysis of functional mechanism of nitric oxide(NO)