TAKEDA Noriaki

J-GLOBAL         Last updated: Nov 23, 2018 at 18:05
TAKEDA Noriaki
The University of Tokushima
Faculty of Medicine, School of Medicine, Department of Otorhinolaryngology and Communicative Neuroscience
(BLANK)(Osaka University)

Research Interests


Research Areas


Academic & Professional Experience

Dec 1999
Jan 1997
Jun 1994
Osaka University, Assistant Professor
Osaka University, Assistant Professor


Mar 1986
Graduated from the Faculty of ---, --- University.
Graduate School, Division of Medicine, Osaka University
Mar 1981
Graduated from the Faculty of ---, --- University.
Faculty of Medicine, Osaka University

Published Papers

Munehisa Fukushima, Tadashi Kitahara, Ryohei Oya, Shiro Akahani, Hidenori Inohara, Shin Naganawa, Noriaki Takeda
Laryngoscope Investigative Otolaryngology   Vol.2(No.6) 344-350   Dec 2017   [Refereed]
Meniere's disease (MD) is a common inner ear disease characterized by repeated episodic vertigo, fluctuating sensorineural hearing loss, and tinnitus. Its pathology is defined as endolymphatic hydrops (EH) in the inner ear and EH has been hypothes...
Eiji Kondou, Osamu Jinnouchi, Seiichi Nakano, Ohnishi Hiroki, Kawata Ikuji, Okamoto Hidehiko, Noriaki Takeda
Clinical Interventions in Aging   Vol.12 1921-1928   Nov 2017   [Refereed]
Fukushima Munehisa, Yokoi Kei, Iga Junpei, Akahania Shiro, Inohara Hidenori, Noriaki Takeda
Acta Oto-Laryngologica   Vol.137(No.11) 1153-1157   Nov 2017   [Refereed]
This study was performed to determine the volume distribution of EH in contralateral DEH. Five contralateral DEH patients (age range = 21-77 years) and one ipsilateral DEH patient. Visualization of in vivo EH using 3T magnetic resonance (MR) imagi...
Yui Takahara, Kumi Satoh, Takaaki Takeyama, Yuki Sakamoto, Toshihito Aoki, 伊藤 美幸, 池田 美穂, 田上 真希, 吉田 充嬉, 岡田 規秀, Jiro Udaka, Aki Shimada, Noriaki Takeda
The Japan Journal of Logopedics and Phoniatrics   Vol.58(No.4) 326-332   Oct 2017   [Refereed]
Takao Imai, Yasumitsu Takimoto, Noriaki Takeda, Tomoko Okumura, Hidenori Inohara
Experimental Brain Research   Vol.235(No.8) 2575-2590   May 2017   [Refereed]
When participants undergo eccentric rotation (ER), i.e., they are rotated while displaced from the axis of rotation, they undergo both rotational stimulation and linear acceleration, which induces both the angular vestibulo-ocular reflex (aVOR) an...
Suzuyo Okazaki, Takao Imai, Kayoko Higashi-Shingai, Kazunori Matsuda, Noriaki Takeda, Tadashi Kitahara, Atsuhiko Uno, Arata Horii, Yumi Ohta, Tetsuo Morihana, Chisako Masumura, Suetaka Nishiike, Hidenori Inohara
Acta Oto-Laryngologica   Vol.137(No.3) 265-269   Mar 2017   [Refereed]
As a canalith repositioning procedure effectively treats H-BPPV with TGPN, but not PGPN, the differentiation between patients with PGPN and with TGPN is essential. The purpose of this study is to determine the observation period enough to distingu...
Naoki Toda, 松岡 百百世, Yohji Hori, Hitoshi Shiyouno, Mika Takahashi, Katsuhiko Nakamura, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.102(No.2) 89-93   Feb 2017   [Refereed]
Takao Imai, Noriaki Takeda, T Ikezono, Kohichiro Shigeno, Masatsugu Asai, Yukio Watanabe, Mamoru Suzuki
Auris, Nasus, Larynx   Vol.44(No.1) 1-6   Feb 2017   [Refereed]
Benign paroxysmal positional vertigo (BPPV) is the most common peripheral vertigo and the posterior and/or lateral semicircular canals are usually affected. BPPV is characterized by brief attacks of rotatory vertigo associated with positional and/...
Noriaki Takeda, Kazunori Matsuda, Gou Satou
耳鼻咽喉科・頭頸部外科   Vol.89(No.1) 36-40   Jan 2017   [Refereed]
Syuji Yonekura, Yoshitaka Okamoto, Daiju Sakurai, Toshioki Sakurai, Tomohisa Iinuma, Heizaburou Yamamoto, Toyoyuki Hanazawa, Shigetoshi Horiguchi, Yuichi Kurono, Kohei Honda, Yuichi Majima, Keisuke Masuyama, Noriaki Takeda, Shigeharu Fujieda, Mitsuhiro Okano, Satoshi Ogino, Kimihiro Okubo
Allergology International   Vol.66(No.3) 425-431   2017   [Refereed]
Many patients who receive CAM report feeling that the effects of treatment provided by hospitals are insufficient and have concerns about the side effects of such treatments. Information regarding standard treatments, as described in the guideline...
Tomoko Okumura, Takao Imai, Yasumitsu Takimoto, Noriaki Takeda, Tadashi Kitahara, Atsuhiko Uno, Takefumi Kamakura, Yasuhiro Osaki, Yoshiyuki Watanabe, Hidenori Inohara
European Archives of Oto-Rhino-Laryngology   Vol.274(No.3) 1413-1421   2017   [Refereed]
M?ni?re's disease is associated with hydrops of the inner ear endolymphatic space, and histopathologically, the cochlea and vestibule are usually involved. We used gadolinium-enhanced magnetic resonance imaging and measured cervical and ocular ves...
Sei-ichi. Nakano, Hidetaka Iwasaki, Eiji Kondou, Katsushi Miyazaki, Haruhiko Shizuku, Sei-ichirou Kamimura, Junya Fukuda, Ryou Kanamura, Noriaki Takeda
The Journal of Medical Investigation : JMI   Vol.63(No.3,4) 227-229   Aug 2016   [Refereed]
Globus pharyngeus (GP) is a common symptom of laryngopharyngeal reflux disease (LPRD), and proton pump inhibitor (PPI) and rikkunshito, a traditional Japanese medicine having prokinetic effect improve LPRD symptoms. In the present study, we examin...
Yoshiro Wada, Suetaka Nishiike, Tadashi Kitahara, Toshiaki Yamanaka, Takao Imai, Taeko Ito, Gou Satou, Kazunori Matsuda, Yoshiaki Kitamura, Noriaki Takeda
Acta Oto-Laryngologica   Vol.136(No.11) 1121-1124   Jul 2016   [Refereed]
After repeated snowboard exercises in the virtual reality (VR) world with increasing time lags in trials 3-8, it is suggested that the adaptation to repeated visual-vestibulosomatosensory conflict in the VR world improved dynamic posture control a...
Hironori Akizuki, Hidetaka Iwasaki, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.109(No.6) 405-409   Jun 2016   [Refereed]
An 88-year-old woman put dodecyl dimethylammonium chloride (quaternary ammonium salt) in her mouth by accident. She spat it out immediately without swallowing, but thereafter, she developed severe oral pain. Twelve hours later, she also developed ...
高石 静, 金村 亮, 藤本 知佐, Koichi Tamura, Koji Abe, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.109(No.6) 393-397   Jun 2016   [Refereed]
Dental implant surgery is carried out in edentulous patients to fix the denture on the foundation of a dental implant body embedded in the maxilla. This procedure has become popular over the last 20 years, and one of the complications is the intru...
Yoshiaki Kitamura, Hiroyuki Mizuguchi, Kentaro Okamoto, Mika Kitayama, Tatsuya Fujii, Akira Fujioka, Toshio Matsushita, Takashi Mukai, Yoshiaki Kubo, Nobuo Kubo, Hiroyuki Fukui, Noriaki Takeda
Acta Oto-Laryngologica   Vol.136(No.4) 409-413   Apr 2016   [Refereed]
Conclusion These findings suggest that low dose irradiation with 310 nm NB-UVB specifically suppressed the up-regulation of H1R gene expression without inducing apoptosis and that UVB of shorter or longer wavelength than 310 nm NB-UVB had no such ...
Takao Imai, Yasumitsu Takimoto, Noriaki Takeda, Atsuhiko Uno, Hidenori Inohara, Shoichi Shimada
PLoS ONE   Vol.11(No.3)    Mar 2016   [Refereed]
To the best of our knowledge, this is the first report of this algorithm being used to calculate a 3D rotation vector of eye movement in mice using high-speed VOG. We developed a technique for analyzing the 3D rotation vector of eye movements in m...
Chisa Fujimoto, Koichi Tamura, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.109(No.3) 183-188   Mar 2016   [Refereed]
An 80-year-old male patient with multiple laryngeal chondromas is reported. Bilateral thyroid cartilage masses were identified incidentally on CT. The masses remained constant in size over a two-year follow-up period, however, pharyngolaryngeal en...
Hiroyuki Mizuguchi, AK Das, Kazutaka Maeyama, S Dev, M Shahriar, Yoshiaki Kitamura, Noriaki Takeda, Hiroyuki Fukui
Journal of Pharmacological Sciences   Vol.130(No.4) 212-218   Feb 2016   [Refereed]
Antihistamines inhibit histamine signaling by blocking histamine H1 receptor (H1R) or suppressing H1R signaling as inverse agonists. The H1R gene is upregulated in patients with pollinosis, and its expression level is correlated with the severity ...
Hiroyuki Mizuguchi, N Orimoto, T Kadota, T Kominami, AK Das, A Sawada, M Tamada, K Miyagi, T Adachi, M Matsumoto, T Kosaka, Yoshiaki Kitamura, Noriaki Takeda, Hiroyuki Fukui
Journal of Pharmacological Sciences   Vol.130(No.3) 151-158   Jan 2016   [Refereed]
Histamine H1 receptor (H1R) gene is upregulated in patients with pollinosis; its expression level is highly correlated with the nasal symptom severity. Antihistamines are widely used as allergy treatments because they inhibit histamine signaling b...
C M Shill, Hiroyuki Mizuguchi, S Karmakar, T Kadota, PK Mukherjee, Yoshiki Kashiwada, Yoshiaki Kitamura, Hisao Nemoto, Noriaki Takeda, Hiroyuki Fukui
International Immunopharmacology   Vol.30 18-26   2016   [Refereed]
Histamine H1 receptor (H1R) gene is upregulated in patients with allergic rhinitis (AR), and its expression level is strongly correlated with the severity of allergic symptoms. We previously reported isolation of the putative anti-allergic compoun...
Eiji Kondou, Osamu Jinnouchi, 大西 皓貴, 川田 育二, Noriaki Takeda
Journal of Otolaryngology of Japa   Vol.118(No.11) 1319-1326   Nov 2015   [Refereed]
Cough and swallowing reflexes are important airway-protective mechanisms against aspiration. Angiotensin-converting enzyme (ACE) inhibitors, one of the side effects of which is cough, have been reported to reduce the incidence of aspiration pneumo...
Yoshiaki Kitamura, H Nakagawa, Tatsuya Fujii, T Sakoda, T Enomoto, Hiroyuki Mizuguchi, Hiroyuki Fukui, Noriaki Takeda
Journal of Pharmacological Sciences   Vol.129(No.3) 183-187   Oct 2015   [Refereed]
In the present study, we examined the effects of antihistamine on the up-regulation of H1R mRNA in the nasal mucosa of patients with pollinosis induced by controlled exposure to pollen using an environmental exposure unit. Out of 20 patients, we d...
Tatsuya Fujii, Kazunori Matsuda, Katsushi Miyazaki, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.108(No.10) 767-773   Oct 2015   [Refereed]
In head and neck cancer, almost all patients treated with chemoradiotherapy suffer from oral mucositis. But, a standard treatment for chemoradiotherapy-induced oral mucositis has not been established. It is considered that the creation of reactive...
Rie Tsutsumi, Masakazu Goda, Chisa Fujimoto, Kyoko Kanno, Misaki Nobe, Yoshiaki Kitamura, Koji Abe, Misako Kawai, Hideki Matsumoto, Tohru Sakai, Noriaki Takeda
The Laryngoscope   Vol.126(No.3) E103-E109   Sep 2015   [Refereed]
We aimed to test the hypothesis that chemotherapy changes the gene expression of taste receptors in the tongue to induce dysgeusia in patients with head and neck cancer. Prospective observation study. We enrolled 21 patients who received chemoradi...
Yuki Nariai, Hiroyuki Mizuguchi, T Ogasawara, H Nagai, Y Sasaki, Y Okamoto, Yoshiyuki Yoshimura, Yoshiaki Kitamura, Hisao Nemoto, Noriaki Takeda, Hiroyuki Fukui
The Journal of Biological Chemistry   Vol.290(No.45) 27393-27402   Sep 2015   [Refereed]
The histamine H1 receptor (H1R) gene is an allergic disease sensitive gene, and its expression level is strongly correlated with the severity of allergic symptoms. (-)-Maackiain was identified as a Kujin-derived anti-allergic compound that suppres...
Hiroyuki Mizuguchi, Y Nariai, S Kato, T Nakano, T Kanayama, Yoshiki Kashiwada, Hisao Nemoto, Kazuyoshi Kawazoe, Yoshihisa Takaishi, Yoshiaki Kitamura, Noriaki Takeda, Hiroyuki Fukui
Pharmacology Research & Perspectives   Vol.3(No.5) e00166-e00166   Aug 2015   [Refereed]
Kujin contains antiallergic compounds that inhibit upregulation of histamine H1 receptor (H1R) and interleukin (IL)-4 gene expression. However, the underlying mechanism remains unknown. We sought to identify a Kujin-derived antiallergic compound a...
Hiroaki Yanagawa, Rumi Katashima, Noriaki Takeda
The Journal of Medical Investigation : JMI   Vol.62(No.3-4) 114-118   Aug 2015   [Refereed]
The first Japanese ethics committee for biomedical research involving human subjects was established at Tokushima University in 1982. Although this committee was not formed as a response to national directives, the government eventually developed ...
内藤 圭介, 島田 亜紀, Masakazu Goda, Aki Endo, Yoshiaki Kitamura, Koji Abe, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.108(No.6) 461-464   Jun 2015   [Refereed]
The adenomatoid odontogenic tumor (AOT) is a rare benign odontogenic tumor that is mostly found in jawbone. It is generally found in the incisor region of the maxilla of young females. It rarely extends into the paranasal sinuses. This article des...
Yoshiaki Kitamura, 三好 仁美, 松岡 百百世, Tatsuya Fujii, Kazunori Matsuda, Noriaki Takeda
Japanese Journal of Rhinology   Vol.54(No.1) 25-30   May 2015   [Refereed]
Masakazu Goda, Osamu Jinnouchi, Tsukasa Takaoka, Koji Abe, Koichi Tamura, Yutaka Nakaya, Yoshihito Furukita, Hirokazu Takechi, Akira Tangoku, Noriaki Takeda
The Journal of Medical Investigation : JMI   Vol.62(No.3-4) 173-176   Mar 2015   [Refereed]
It is suggested that therapeutic PEG placement is useful for preventing unplanned interruption of CRT in patients with advanced head and neck cancer. After severe mucositis and inadequate oral intake have developed during CRT, PEG placement should...
Takao Imai, Kazunori Matsuda, Noriaki Takeda, Atsuhiko Uno, Tadashi Kitahara, Arata Horii, Suetaka Nishiike, Hidenori Inohara
BMJ Open   Vol.5(No.1)    Jan 2015   [Refereed]
Geotropic or apogeotropic positional nystagmus was recorded by video-oculography and analysed three-dimensionally.
松岡 百百世, Yoshiaki Kitamura, Aki Endo, Koji Abe, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.108(No.1) 13-17   Jan 2015   [Refereed]
We report herein on a 75-year-old woman with sinonasal-type hemangiopericytoma (HPC). She complained of nasal bleeding and a nasal tumor originated from the left nasal septum was found. It was successfully resected using endoscopic sinus surgery w...
太原 一彦, Kazunori Sekine, Gou Satou, Kazunori Matsuda, 神村 盛一郎, Takahiro Azuma, Noriaki Takeda
Equilibrium Research   Vol.74(No.1) 15-19   Jan 2015   [Refereed]
In the present study, we examined the temperature of aural air stimulation that was equivalent to aural stimulation with water at 20°C in the caloric test. In 10 ears of 5 healthy volunteers, the maximum slow phase eye velocities (MSPEVs) of nysta...
Noriaki Takeda, 神村 盛一郎, 嶽村 貞治, 太田 有美, 森鼻 哲生, 猪原 秀典, Yoshiaki Kitamura, Koji Abe
Otology Japan   Vol.24(No.5) 760-765   Dec 2014   [Refereed]
Takahiro Azuma, 高橋 美香, Hidetaka Iwasaki, Naoki Toda, Katsuhiko Nakamura, Noriaki Takeda
Facial Nerve Research Japan   Vol.34 81-83   Dec 2014   [Refereed]
Katsuhiko Nakamura, Takahiro Azuma, Naoki Toda, Hidetaka Iwasaki, Noriaki Takeda
Facial Nerve Research Japan   Vol.34 78-80   Dec 2014   [Refereed]
Eiji Kondou, Osamu Jinnouchi, Hiroki Ohnishi, Ikuji Kawata, Seiichi Nakano, Masakazu Goda, Yoshiaki Kitamura, Koji Abe, Hiroshi Hoshikawa, Hidehiko Okamoto, Noriaki Takeda
Clinical Interventions in Aging   Vol.9 1661-1667   Sep 2014   [Refereed]
In the present study, an attempt was made to examine the effects of aural stimulation with ointment containing capsaicin on swallowing function in order to develop a novel and safe treatment for non-obstructive dysphagia in elderly patients. A pro...
坂上 雅史, 黒野 祐一, 井之口 昭, Noriaki Takeda, 愛場 庸雅, 任 智美, 池田 稔
Journal of Otolaryngology of Japa   Vol.117(No.8) 1093-1101   Aug 2014   [Refereed]
In a taste disorder, an agreement between patients complaints and gustatory function test results is not necessarily found both at the initial hospital visit and during the course of treatment; therefore, it is difficult to assess treatment respon...
Gou Satou, Kazunori Sekine, Kazunori Matsuda, Hitomi Ueeda, Arata Horii, Suetaka Nishiike, Tadashi Kitahara, Atsushi Uno, Takao Imai, Hidenori Inohara, Noriaki Takeda
Acta Oto-Laryngologica   Vol.134(No.10) 1005-1010   Jul 2014   [Refereed]
Abstract Conclusion: The finding of deteriorated hearing loss at the initial visit at middle to high frequencies is a factor of poor hearing prognosis in M?ni?re's disease. Early intervention with instructions for lifestyle changes may lead to goo...
大西 皓貴, 高橋 美香, Koji Abe, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.107(No.5) 369-374   May 2014   [Refereed]
We report herein on a 19-year-old female with Langerhans cell histiocytosis (LCH) of the temporal bone. She complained of right ear fullness and showed conductive hearing loss of the right ear. CT imaging showed a tumor in the temporal bone and mu...
Yoshiaki Kitamura, Hiroyuki Mizuguchi, Hiroyuki Fukui, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.107(No.4) 261-270   Apr 2014   [Refereed]
We are focusing on the histamine H1 receptor (H1R) as an allergic disease-sensitive gene. H1R is a rate-limiting molecule of the H1R signal because the signal is increased with elevated receptor expression levels. We discovered that the...
庄野 仁志, Takahiro Azuma, Kazunori Sekine, Koji Abe, Koichi Tamura, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.107(No.2) 141-145   Feb 2014   [Refereed]
Descending necrotizing mediastinitis (DNM) requires an early and aggressive surgical approach. We report herein on a case of DNM in which continuous saline irrigation with a pleated drain was found to be useful. A 71-year-old man presented with a ...
Suzuyo Okazaki, Suetaka Nishiike, Hiroshi Watanabe, Takao Imai, Atsuhiko Uno, Tadashi Kitahara, Arata Horii, Takefumi Kamakura, Yasumitsu Takimoto, Noriaki Takeda, Hidenori Inohara
Acta Oto-Laryngologica   Vol.133(No.3) 246-252   Nov 2013   [Refereed]
Repeated optic flow caused no significant change of body deviation or the time course of the gait termination process in comparison with that in the control. The walking velocity at the start of the termination process showed short-term flexibilit...
Ryo Kanamura, Masakazu Goda, Seiichiro Kamimura, Hideyuki Nakagawa, Jiro Udaka, Koichi Tamura, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.106(No.9) 797-802   Sep 2013   [Refereed]
We report herein on a case with pyoderma gangrenosum in the nasal root associated with ulcerative colitis. Pyoderma gangrenosum is characterized by progressive skin necrosis and is often associated with chronic bowel inflammatory diseases such as ...
Izumi Chida, Koichi Tamura, Shin-ichi Nakagawa, Masahiro Ando, Kuno Emi, Hoshikawa Hiroshi, Mori Nozomu, Noriaki Takeda
Auris, Nasus, Larynx   Vol.40(No.4) 383-387   Aug 2013   [Refereed]
Outcomes of tracheoesophageal diversion and laryngotracheal separation were evaluated in 15 neurologically impaired children treated for intractable aspiration. A retrospective analysis of the hospital records was carried out in 15 consecutive ped...
Gou Satou, Kazunori Sekine, Kazunori Matsuda, Noriaki Takeda
Acta Oto-Laryngologica   Vol.133(No.11) 1124-1127   Jul 2013   [Refereed]
The findings suggest that in patients with posterior semicircular canal (PSCC) benign paroxysmal positional vertigo (P-BPPV), head trauma and prolonged bedrest, but not inner ear disease, are risk factors for poor outcome of a single Epley maneuve...
Seiichiro Kamimura, Aki Endo, Koji Abe, Yoshiaki Kitamura, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.106(No.7) 585-589   Jul 2013   [Refereed]
We report herein on an intractable case of MPO-ANCA-associated middle ear disease with sensorineural hearing loss and facial palsy. A 73-year-old female complained of otitis media-like symptoms, but the treatment for otitis media with effusion was...
Takao Imai, Chisako Masumura, Noriaki Takeda, Tadashi Kitahara, Atsuhiko Uno, Arata Horii, Suetaka Nishiike, Yumi Ohta, Kayoko Shingai-Higashi, Tetsuo Morihana, Suzuyo Okazaki, Takefumi Kamakura, Yasumitsu Takimoto, Hidenori Inohara
Acta Oto-Laryngologica   Vol.133(No.6) 594-599   Jun 2013   [Refereed]
In the patient with true anterior canalolithiasis, the direction of positional nystagmus during reverse Epley maneuver was constant and its axis was perpendicular to the plane of the right ASCC three-dimensionally. In contrast, in the patient with...
Hinami Nagashima, Jiro Udaka, Izumi Chida, Aki Shimada, Eiji Kondo, Noriaki Takeda
Auris, Nasus, Larynx   Vol.40(No.6) 534-538   May 2013   [Refereed]
These findings suggest that bone-conduction ASSR can assess the normal or near normal cochlear sensitivity in young children with conductive hearing loss. It is also suggested that ASSR-estimated ABG can be used clinically to predict their accurat...
Seiichi Nakano, Hironori Akizuki, Hidetaka Iwasaki, Satoko Yamashita, Yoshiyuki Fujii, Eiji Kondo, Haruhiko Shizuku, Koichi Tamura, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.106(No.5) 439-445   May 2013   [Refereed]
We report herein on a case of laryngocele with recurrent infection. A 48-year-old male complained of hoarseness and swelling of the left side of his neck. The endoscopic and CT scan examinations demonstrated the combined type of laryngocele that h...
Kazunori Matsuda, Kazunori Sekine, Gou Satou, Haruhiko Shizuku, Noriaki Takeda
Otologia Fukuoka   Vol.59(No.3) 115-121   May 2013   [Refereed]
Diphenidol and betahistine are anti-vertigo medications used for the treatment of vertiginous disorders. In the present study, we compared the therapeutic effects of diphenidol and betahistine on the handicap in daily life due to vertigo in patien...
Wakana Kuroda, Yoshiaki Kitamura, Hiroyuki Mizuguchi, Yuko Miyamoto, Bukasa Kalubi, Hiroyuki Fukui, Noriaki Takeda
Journal of Pharmacological Sciences   Vol.122(No.1) 55-58   Apr 2013   [Refereed]
An attempt was made to clarify the additive suppressive effects of pranlukast, a cysteinyl leukotriene-receptor (LTR) antagonist, in combination with chlorpheniramine, an antihistamine, on the up-regulation of histamine H1-receptor (H1R) mRNA in t...
Hidetaka Iwasaki, Naoki Toda, Mika Takahashi, Takahiro Azuma, Katsuhiko Nakamura, Shoichiro Takao, Masafumi Harada, Noriaki Takeda
Acta Oto-Laryngologica   Vol.133(No.4) 373-377   Apr 2013   [Refereed]
It is suggested that vertigo in patients with Ramsay Hunt syndrome is mostly induced by superior vestibular neuritis consecutive to the reactivation of varicella-zoster virus (VZV) infection from the geniculate ganglion through the faciovestibular...
高橋 美香, Naoki Toda, Noriaki Takeda
耳鼻咽喉科ニューロサイエンス   Vol.27 55-57   Apr 2013   [Refereed]
Atsuo Takeichi, Hidetaka Iwasaki, Hironori Akizuki, Ryo Kanamura, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.106(No.3) 229-233   Mar 2013   [Refereed]
We report three patients with tetanus who complained of dysphagia. All cases showed trismus, however, physical, serological and endoscopic examinations revealed not abnormalities. Under the diagnosis of tetanus, intravenous penicillin was administ...
Masashi Hattori, Hiroyuki Mizuguchi, Yuko Baba, Shohei Ono, Tomohiro Nakano, Qian Zhang, Yohei Sasaki, Makoto Kobayashi, Yoshiaki Kitamura, Noriaki Takeda, Hiroyuki Fukui
International Immunopharmacology   Vol.15(No.2) 232-239   Jan 2013   [Refereed]
It has been reported that the histamine H1 receptor (H1R) gene is up-regulated in patients with allergic rhinitis and H1R expression level strongly correlates with the severity of allergy symptoms. Accordingly compounds that suppress the H1R gene ...
Tatsuya Fujii, Masakazu Goda, Kazunori Matsuda, Katsushi Miyazaki, Kazuhide Mineda, Koji Nakagawa, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.106(No.1) 13-16   Jan 2013   [Refereed]
Frey's syndrome is a complication associated with parotid tumor operation. We report herein on a 70-year-old man who developed Frey's syndrome after fracturing his mandibular condyle. Although he underwent manipulative reduction, but not an operat...
Minoru Ikeda, Yuichi Kurono, Akira Inokuchi, Noriaki Takeda, Tsunemasa Aiba, Yasuyuki Nomura, Masafumi Sakagami
Journal of Otolaryngology of Japa   Vol.116(No.1) 17-26   Jan 2013   [Refereed]
Diagnosis and treatment of taste disorders are challenging because the disorder can only be determined by the awareness of the patient. Hence, these disorders still require comprehensive evidence. We conducted a randomized, placebo-controlled doub...
Takahiro Azuma, 高橋 美香, Naoki Toda, Hidetaka Iwasaki, Katsuhiko Nakamura, Noriaki Takeda
Facial Nerve Research Japan   Vol.33 166-168   2013   [Refereed]
Katsuhiko Nakamura, 高橋 美香, Naoki Toda, Takahiro Azuma, Hidetaka Iwasaki, Noriaki Takeda
Facial Nerve Research Japan   Vol.33 160-162   2013   [Refereed]
佐藤 公美, Jiro Udaka, 長嶋 比奈美, 森実 加奈, 伊藤 美幸, 合田 侑以, 石原 章子, Noriaki Takeda
The Japan Journal of Logopedics and Phoniatrics   Vol.54 14-19   2013   [Refereed]
In the present study, an attempt was made to investigate the correlation between self-voicing and non-self-voicing, and environmental sound in professional voice abusers. For this purpose, we used a hearing aid with data logging system. Kindergart...
S. Nishiike, S. Okazaki, H. Watanabe, Hironori Akizuki, T. Imai, A. Uno, T. Kitahara, A. Horii, Noriaki Takeda, H. Inohara
The Journal of Medical Investigation : JMI   Vol.60 236-239   2013   [Refereed]
In this study, we examined the effects of sensory inputs of visual-vestibulosomatosensory conflict induced by virtual reality (VR) on subjective dizziness, posture stability and visual dependency on postural control in humans. Eleven healthy young...
高橋 美香, Takahiro Azuma, Katsuhiko Nakamura, Noriaki Takeda
Facial Nerve Research Japan   Vol.33 62-64   2013   [Refereed]
Eiji Kondo, Ikuji Kawata, Tsukasa Takaishi, Ritsuko Abe, Yohji Hori, Masakazu Goda, Aki Shimada, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.106(No.3) 203-206   2013   [Refereed]
In order to clarify the role of arteriosclerosis in the development of and recovery from sudden deafness, we evaluated arteriosclerosis in patients with sudden deafness, using pulse wave velocity (PWV) as a marker. Arteriosclerosis was observed in...
Izumi Chida, 島田 亜紀, Jiro Udaka, 佐藤 公美, 長嶋 比奈美, Noriaki Takeda
Padiatric Otorhinolaryngology Japan   Vol.34(No.3) 345-351   2013   [Refereed]
Hiroyuki Mizuguchi, Miyagi Kohei, Terao Takuma, Sakamoto Noriko, Yamawaki Yosuke, Adachi Tsubasa, Ono S., Sasaki Y., Yoshiyuki Yoshimura, Yoshiaki Kitamura, Noriaki Takeda, Hiroyuki Fukui
Scientific Reports   Vol.2 916-916   Dec 2012   [Refereed]
Takahiro Azuma, Hidetaka Iwasaki, Naoki Toda, Katsuhiko Nakamura, Noriaki Takeda
Facial Nerve Research Japan   Vol.32 68-70   Nov 2012   [Refereed]
高橋 美香, Naoki Toda, Takahiro Azuma, Hidetaka Iwasaki, Katsuhiko Nakamura, Noriaki Takeda
Facial Nerve Research Japan   Vol.32 113-115   Nov 2012   [Refereed]
Takao Imai, Noriaki Takeda, Atsuhiko Uno, Arata Horii, Tadashi Kitahara, Suetaka Nishiike, Kayoko Higashi-Shingai, Hidenori Inohara
Auris, Nasus, Larynx   Vol.39(No.5) 544-548   Oct 2012   [Refereed]
Three kind of nystagmus, namely P-BPPV, AH-BPPV and GH-BPPV can be explained by the otoconial debris hypothesis of the same ear. Finally, the recently reported geotropic nystagmus with a long time constant may be explained by a reversible lesion s...
Osamu Jinnouchi, Tomomi Kuwahara, Shiro Ishida, Yoshiro Okano, Yasuko Kasei, Kazufumi Kunitomo, Noriaki Takeda
Auris, Nasus, Larynx   Vol.39(No.4) 374-377   Aug 2012   [Refereed]
These findings indicate that modified Burow's solution, in addition to bearing a broad antimicrobial activity, is as effective as the original Burow's solution in the treatment of chronic suppurative otitis.
Junya FUKUDA, Masakazu Goda, Chisa Fujimoto, Tetsuo IKEZONO, Takashi NAKAGAWA, Hiroshi HIBINO, Yoshiaki Kitamura, Koji Abe, Koichi Tamura, Noriaki Takeda
Otology Japan   Vol.22(No.3) 274-279   Jul 2012   [Refereed]
Mie SHIMATANI, Jiro Udaka, Yoshimitsu Shimatani, Izumi Chida, Aki SHIMADA, Koichi Tamura, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.105(No.6) 571-575   Jun 2012   [Refereed]
We report on a 79-year-old woman complaining of progressive dysphagia as an initial symptom of tetanus. Endoscopic and videofluoroscopic examination of her swallowing process showed dysphagea with food retention in the pyriform sinus, probably bec...
Gou Satou, Kazunori Sekine, Kazunori Matsuda, Noriaki Takeda
Acta Oto-Laryngologica   Vol.132(No.6) 614-617   Jun 2012   [Refereed]
The side of the affected ear was significantly associated with the head-lying side during sleep in patients with P-BPPV and was closely but not significantly associated with it in patients with H-BPPV. However, the head-lying side during sleep did...
Cisa Fujimoto, Noriaki Takeda, A Matsunaga, A Sawada, T Tanaka, Takashi Kimoto, Wakako Shinahara, Takako Sawabuchi, Miyoko Yamaguchi, M Hayama, Hiroaki Yanagawa, Mihiro Yano, Hiroshi Kido
Influenza and Other Respiratory Viruses   Vol.6(No.6) 396-403   Jun 2012   [Refereed]
To determine the induction and changes in anti-influenza virus secretory IgA (s-IgA) levels in nasal washes and serum IgG levels in patients with influenza. The study recruited 16 patients with influenza aged 35.6 ± 9.6 years in 2007/2008 and 2008...
Kazunori MATSUDA, Ikuji KAWATA, Ritsuko ABE, Yoshiaki Kitamura, Kazunori Sekine, Koji Abe, Koichi Tamura, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.105(No.4) 375-379   Apr 2012   [Refereed]
We examined the effect of oral administration of beraprost sodium, a derivative of prostaglandin I2 (PGI2) in patients with sudden deafness as a salvage treatment after failure of initial systemic steroid therapy with prostaglandin E1. We then com...
Yoshiaki Kitamura, Hiroyuki Mizuguchi, Hirotaka Ogishi, Wakana Kuroda, Masashi Hattori, Hiroyuki Fukui, Noriaki Takeda
Acta Oto-Laryngologica   Vol.132(No.4) 434-438   Apr 2012   [Refereed]
These findings suggest that the down-regulation of interleukin (IL)-5 gene expression in collaboration with the suppression of histamine H(1) receptor (H1R) gene expression in the nasal mucosa provides the basis for better therapeutic effects of p...
Kayoko Higashi-Shingai, Takao Imai, Noriaki Takeda, Atsuhiko Uno, Suetaka Nishiike, Arata Horii, Tadashi Kitahara, Yuka Fuse, Misako Hashimoto, Osamu Senba, Tsuyoshi Suzuki, Toshiaki Fujita, Hideo Otsuki, Hidenori Inohara
Auris, Nasus, Larynx   Vol.39(No.2) 216-219   Apr 2012   [Refereed]
Since the cerebellar vermis is known to plays an inhibitory role on the central vertical vestibule-ocular reflex (VOR), the present results suggest that the spontaneous UBN in darkness observed in this patient was induced by an imbalance of centra...
Arata Horii, Aya Nakagawa, Atsuhiko Uno, Tadashi Kitahara, Takao Imai, Suetaka Nishiike, Noriaki Takeda, Hidenori Inohara
Brain Research   Vol.1435 91-98   Jan 2012   [Refereed]
We previously reported that motion sickness was prevented in rats with amygdala lesion and that provocative motion stimuli increased the number of Fos-positive neurons in the amygdala, suggesting that the amygdala is one of the neural substrates i...
Nobuko Sarukura, Shinji Takai, Shinji Ikemoto, Tomoo Korin, Yukiko Ueda, Yoshiaki Kitamura, Bukasa Kalubi, Shigeru Yamamoto, Noriaki Takeda
Auris, Nasus, Larynx   Vol.39(No.3) 294-297   Jan 2012   [Refereed]
These findings suggest that ACE ratio is as sensitive as serum zinc concentration for the evaluation of zinc deficiency and can be used for the biochemical diagnosis of zinc nutritional status in patients with zinc deficiency-induced taste impairm...
Noriaki Takeda
Journal of Otolaryngology of Japa   Vol.115(No.10) 932-933   2012   [Refereed]
高橋 美香, Takahiro Azuma, Katsuhiko Nakamura, Hidetaka Iwasaki, Naoki Toda, Noriaki Takeda
Facial Nerve Research Japan   Vol.31 148-150   Dec 2011   [Refereed]
Noriaki Takeda
Facial Nerve Research Japan   Vol.31 29-30   Dec 2011   [Refereed]
川田 仁美, Izumi Chida, Kazunori Matsuda, Gou Satou, Seizo Oyama, 石谷 保夫, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.104(No.10) 689-695   Oct 2011   [Refereed]
We report a case of infantile middle-ear teratoma. A 6-month-old girl was first seen and reported to have a history of refractory left-ear otitis media. Computed tomography (CT) and magnetic resonance imaging (MRI) showed a tumor occupying the tym...
Nobuko Sarukura, Miho Kogirima, Shinji Takai, Yoshiaki Kitamura, Bukasa Kalubi, Shigeru Yamamoto, Noriaki Takeda
The Journal of Medical Investigation : JMI   Vol.58(No.3-4) 203-209   Aug 2011   [Refereed]
In the present study, we first examined the dietary zinc intake from food groups in 109 healthy Japanese (24-82 years old, 45 male and 64 female) by means of the 72-h recall method. We then used the ratio of apo/holo-activities of angiotensin conv...
Mohammed Islam Nurul, Hiroyuki Mizuguchi, Masum Shahriar, Pichairajan Venkatesh, Kazutaka Maeyama, K Pulok Mukherjee, Masashi Hattori, Kabir Mohamed Sahabuddin Choudhuri, Noriaki Takeda, Hiroyuki Fukui
International Immunopharmacology   Vol.11(No.11) 1766-1772   Jul 2011   [Refereed]
Histamine plays major roles in allergic diseases and its action is mediated mainly by histamine H(1) receptor (H1R). We have demonstrated that histamine signaling-related H1R and histidine decarboxylase (HDC) genes are allergic diseases sensitive ...
Hiroyuki Mizuguchi, Takuma Terao, Mika Kitai, Mitsuhiro Ikeda, Yoshiyuki Yoshimura, Asish Kumar Das, Yoshiaki Kitamura, Noriaki Takeda, Hiroyuki Fukui
The Journal of Biological Chemistry   Vol.286(No.35) 30542-30551   Jul 2011   [Refereed]
The histamine H(1) receptor (H1R) gene is up-regulated in patients with allergic rhinitis. However, the mechanism and reason underlying this up-regulation are still unknown. Recently, we reported that the H1R expression level is strongly correlate...
Seiichi NAKANO, Haruhiko Shizuku, Hironori Akizuki, Hidetaka Iwasaki, Koichi SHICHIJOU, Takeshi OGOSE, Tsutomu Watanabe, Tadanori NAKATSU, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.104(No.5) 347-352   May 2011   [Refereed]
We report a case of PFAPA (Periodic fever with aphthous stomatitis, pharyngitis and cervical adenitis). A 5-year-old boy admitted for idiopathic fever 12 times within 8-months. Fever of >38°C occurred for 5 days at 10-to-20-days intervals. Antibio...
Noriaki Takeda, 神村 盛一郎, Izumi Chida, Yoshiaki Kitamura, Osamu Jinnouchi, Koji Abe, Koichi Tamura, Jiro Udaka, Aki Endo
Otology Japan   Vol.21(No.5) 808-815   May 2011   [Refereed]
Kana MORIZANE, Kumi SATOU, Akane MINEOI, Yui GODA, Hinami NAGASHIMA, Jiro Udaka, Noriaki Takeda
The Japan Journal of Logopedics and Phoniatrics   Vol.52(No.2) 183-188   Apr 2011   [Refereed]
Two hundred thirty-one preschool children received language disorder screening in school medical examinations. Pre-screening by speech-language-hearing-therapists found 47 children were suspected to have language disorders, and medical examination...
Hideyuki Nakagawa, Yohji Hori, Seizo Oyama, Koichi Tamura, Noriaki Takeda, Kazunori MATSUDA
Practica Oto-Rhino-Laryngologica   Vol.104(No.3) 187-191   Mar 2011   [Refereed]
Chemosurgery with Mohs' paste created by Frederic E. Mohs, is microscopically controlled to treat common skin cancer. This was repeated for a 68-year-old woman with recurrent malignant spindle cell carcinoma of the maxillary sinus, who suffered fr...
Hiroyuki Mizuguchi, Yoshiaki Kitamura, Yuto Kondo, Wakana Kuroda, Haruka Yoshida, Yuko Miyamoto, Masashi Hattori, Noriaki Takeda, Hiroyuki Fukui
Journal of the Pharmaceutical Society of Japan   Vol.131(No.2) 171-178   Feb 2011   [Refereed]
Therapeutics targeting disease-sensitive genes are required for the therapy of multifactorial diseases. There is no clinical report on therapeutics for allergic disease-sensitive genes. We are focusing on the histamine H1 receptor (H1R) as a sensi...
Noriaki Takeda, Mahito Ito, Hidenori Inohara
Auris, Nasus, Larynx   Vol.38(No.1) 2-5   Feb 2011   [Refereed]
OBJECTIVE: The purpose of this study was to assess the natural course of positional vertigo in patients with the apogeotropic variant of horizontal canal type of benign paroxysmal positional vertigo (AH-BPPV), which is reported to be more refracto...
中山 壽孝, Yoshiaki Kitamura, Noriaki Takeda
Japanese Journal of Rhinology   Vol.49(No.4) 474-480   Dec 2010   [Refereed]
Hayato Umehara, Hiroyuki Mizuguchi, N Mizukawa, M Matsumoto, Noriaki Takeda, E Senba, Hiroyuki Fukui
Methods and Findings in Experimental and Clinical Pharmacology   Vol.32(No.10) 733-736   Dec 2010   [Refereed]
It has been well established that histaminergic neurons innervate densely the anterior hypothalamus and regulate several functions through the histamine H receptor (H1R). However, the physiological function of the histaminergic neurons in other re...
高橋 美香, Naoki Toda, Takahiro Azuma, Hidetaka Iwasaki, Katsuhiko Nakamura, Noriaki Takeda
Facial Nerve Research Japan   Vol.30 179-180   Dec 2010   [Refereed]
Naoki Toda, 高橋 美香, Takahiro Azuma, Hidetaka Iwasaki, Katsuhiko Nakamura, Noriaki Takeda
Facial Nerve Research Japan   Vol.30 75-77   Dec 2010   [Refereed]
Katsuhiko Nakamura, 高橋 美香, Naoki Toda, Takahiro Azuma, Hidetaka Iwasaki, Seizo Oyama, Noriaki Takeda
Facial Nerve Research Japan   Vol.30 137-139   Dec 2010   [Refereed]
Hiroyuki Mizuguchi, Yoshiaki Kitamura, Y Kondo, W Kuroda, H Yoshida, Y Miyamoto, M Hattori, Hiroyuki Fukui, Noriaki Takeda
Methods and Findings in Experimental and Clinical Pharmacology   Vol.32(No.10) 745-748   Dec 2010   [Refereed]
Administration of antihistamines 2-4 weeks before the pollen season showed a greater inhibitory effect on nasal allergy symptoms in patients with seasonal allergic rhinitis. However, the mechanism of slow-onset effects of preseasonal treatment wit...
Hideo Shojaku, Yukio Watanabe, Noriaki Takeda, Tetsuo Ikezono, Masahiro Takahashi, Akinobu Kakigi, Juichi Ito, Katsumi Doi, Mamoru Suzuki, Masaya Takumida, Katsumasa Takahashi, Hiroshi Yamashita, Izumi Koizuka, Shinichi Usami, Mitsuhiro Aoki, Hideaki Naganuma
Acta Oto-Laryngologica   Vol.130(No.10) 1135-1140   Oct 2010   [Refereed]
CONCLUSION: Similarly to almost all delayed endolymphatic hydrops (DEH) cases with both precedent sudden deafness and mumps deafness, two-thirds of DEH cases with precedent deafness of unknown cause with onset in early childhood developed DEH symp...


Izumi Chida, Noriaki Takeda
小児科   Vol.58(No.9) 1063-1068   Aug 2017
Noriaki Takeda
Journal of Otolaryngology of Japa   Vol.120(No.1) 9-14   Jan 2017
Aki Shimada, Jiro Udaka, Noriaki Takeda
JOHNS   Vol.33(No.10) 1479-1490   2017
Izumi Chida, Noriaki Takeda
JOHNS   Vol.33(No.1) 97-101   2017
Noriaki Takeda
Padiatric Otorhinolaryngology Japan   Vol.37(No.3) 340-342   Jun 2016
近藤 昭男, Noriaki Takeda
耳鼻咽喉科・頭頸部外科   Vol.88(No.5) 196-198   Apr 2016
Gou Satou, Noriaki Takeda
耳鼻咽喉科・頭頸部外科   Vol.88(No.5) 238-241   Apr 2016
Noriaki Takeda
耳鼻咽喉科・頭頸部外科   Vol.88(No.3) 248-251   Mar 2016
Noriaki Takeda
日耳鼻専門医通信   119-220   2016
Noriaki Takeda
Journal of Otolaryngology of Japa   Vol.118(No.11) 1349-1351   Nov 2015
Gou Satou, Noriaki Takeda
内科   Vol.114(No.6) 1083-1086   Dec 2014
Noriaki Takeda
脳21   Vol.17(No.3) 269-270   Jul 2014
Takahiro Azuma, Noriaki Takeda
脳21   Vol.17(No.3) 360-366   Jul 2014
Noriaki Takeda
Medical ASAHI   37-39   Jul 2014
Noriaki Takeda
ENTONI   Vol.162 1-4   Jan 2014
Noriaki Takeda
鼻アレルギーフロンティア   Vol.14(No.2) 108-109   2014
Noriaki Takeda
ENT Compass   176-179   2014
Noriaki Takeda
Journal of Otolaryngology of Japa   Vol.116(No.4) 1185-1191   Nov 2013
Noriaki Takeda
Pharma Medica   Vol.31 55-58   Oct 2013
Gou Satou, Noriaki Takeda
ENTONI   Vol.158 64-70   Sep 2013
Noriaki Takeda
ENTONI   Vol.158 71-75   Sep 2013
Takahiro Azuma, Noriaki Takeda
ENT臨床フロンティア 口腔・咽頭疾患,歯牙関連疾患を診る   197-198   Aug 2013
【メニエール病Update】 診療ガイドライン
Noriaki Takeda, Kazunori Matsuda
耳鼻咽喉科・頭頸部外科   Vol.84(No.13) 985-988   Dec 2012
Noriaki Takeda
ENT臨床フロンティア めまいを見分ける・治療する   300-302   Oct 2012
Noriaki Takeda
ENT臨床フロンティア 急性難聴の鑑別とその対処   191-192   Aug 2012
Noriaki Takeda
ENT臨床フロンティア 急性難聴の鑑別とその対処   189-190   Aug 2012
Noriaki Takeda, Gou Satou
ENTONI   Vol.141 45-49   Jun 2012
Noriaki Takeda, Gou Satou
ENTONI   Vol.139 39-43   Apr 2012
Noriaki Takeda, Gou Satou
JOHNS   Vol.28(No.2) 167-171   Feb 2012
Gou Satou, Noriaki Takeda
Clinical Neuroscience   Vol.30(No.1) 68-73   Jan 2012
Yoshiaki Kitamura, Hiroyuki Mizuguchi, Hiroyuki Fukui, Noriaki Takeda
Clinical Immunology & Allergology   Vol.57(No.1) 45-51   Jan 2012
Yoshiaki Kitamura, Hiroyuki Mizuguchi, Hiroyuki Fukui, Noriaki Takeda
JOHNS   Vol.28(No.1) 55-58   Jan 2012
小川 郁, 北川 泰久, 寺本 明, Noriaki Takeda, 木村 健二郎
The Journal of the Japan Medical Association   Vol.140(No.10) 2049-2061   Jan 2012
高橋 美香, Noriaki Takeda
JOHNS   Vol.27(No.12) 1939-1942   Dec 2011
Yoshiaki Kitamura, Hiroyuki Mizuguchi, Hiroyuki Fukui, Noriaki Takeda
Pediatrics of Japan   Vol.52(No.6) 853-858   May 2011
Yoshiaki Kitamura, Hiroyuki Mizuguchi, Hiroyuki Fukui, Noriaki Takeda
頭頚部自律神経   Vol.25 33-35   Apr 2011
Noriaki Takeda
レジデントノート別冊救急・ERノート1   218-222   Apr 2011
Noriaki Takeda
Japan Medical Journal   Vol.0(No.4524) 55-60   Jan 2011
【お母さんへの回答マニュアル耳鼻咽喉科Q&A 2010】 耳編 めまい・動揺病 めまいはどうして起こるのでしょうか?
Noriaki Takeda
JOHNS   Vol.26(No.9) 1294-1295   Sep 2010
【内科医のための耳鼻科疾患の診かたと治療】 内科医が留意すべき耳鼻科疾患の診断と治療,予防 患者の症状から見逃さないためのコツとポイント めまい
Kazunori Sekine, Noriaki Takeda
Progress in Medicine   Vol.30(No.4) 1025-1029   Apr 2010
【予防医学からみた耳鼻咽喉科臨床】 予防医学からみた高齢者の平衡障害
西池 季隆, Noriaki Takeda, 渡邊 洋
JOHNS   Vol.25(No.12) 1747-1750   Dec 2009
神経科学の素朴な疑問 宇宙酔いのメカニズムはどのようなものか?
Noriaki Takeda
Clinical Neuroscience   Vol.27(No.7) 831-831   Jul 2009
【メニエール病を理解する】 メニエール病の診断基準と検査の進め方
Noriaki Takeda
JOHNS   Vol.25(No.6) 815-821   Jun 2009
【訴えからみためまいの見分け方】 繰り返す回転性めまい
Gou Satou, Noriaki Takeda
ENTONI   Vol.102 9-17   May 2009
Osamu Jinnouchi, Noriaki Takeda
深在性真菌症: SFI Forum   Vol.5(No.1) 28-30   Apr 2009
渡辺 行雄, 池園 哲郎, 伊藤 壽一, 柿木 章伸, 肥塚 泉, 鈴木 衞, 高橋 克昌, 工田 昌也, Noriaki Takeda, 土井 勝美, 山下 裕司, 青木 光広, 宇佐美 真一, 高橋 正紘, 長沼 英明
Equilibrium Research   Vol.68(No.2) 103-106   Apr 2009
【耳鼻咽喉科ウイルス感染症】 めまいとウイルス感染
Noriaki Takeda, Naoki Toda
ENTON   Vol.99 17-23   Mar 2009
【異物 初期対応から摘出まで】耳鼻咽喉科領域の異物 成人例の特徴
Koichi Tamura, Noriaki Takeda
ENTONI   Vol.96 30-35   Dec 2008
Katsuhiko Nakamura, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.101(No.6) 413-421   Jun 2008
Synkinesis is the most unpleasant sequelae of peripheral facial palsy. It is an abnormal involuntary associate facial movement such as eye closure during smiling and mouth movement during blinking. Synkinesis strongly reduces the quality of life; ...
【難聴の神経学】 Meniere病
Gou Satou, Noriaki Takeda
神経内科   Vol.68(No.5) 422-428   May 2008
【高齢者のめまい診断におけるpitfall】 高齢者のメニエール病
Noriaki Takeda
ENTONI   Vol.87 63-66   Apr 2008
Yoshiaki Kitamura, Noriaki Takeda
アレルギーと神経ペプチド   Vol.4 33-41   Feb 2008
Kazunori Sekine, Noriaki Takeda
耳鼻咽喉科・頭頸部外科   Vol.80(No.1) 55-64   Jan 2008
めまい 耳鼻科的立場から
Noriaki Takeda
メディカルノート症候がわかる   92-93   Dec 2007
今井 貴夫, Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.100(No.8) 599-613   Aug 2007
We developed a new video-oculography (VOG) system that can facilitate analysis of the axis angle, rotation vector or quaternions of eye movements. The axis angle, rotation vector, and quaternions measure a single rotation from a chosen reference p...
Jiro Udaka, Koichi Tamura, Noriaki Takeda
日本小児呼吸器疾患学会雑誌   Vol.18(No.1) 98-101   Jun 2007
急性めまいと慢性めまい -診断・治療の差- めまいの薬物治療のEBM評価
Noriaki Takeda
ENTONI   Vol.75(No.0) 31-36   May 2007
Osamu Jinnouchi, Noriaki Takeda
耳鼻咽喉科・頭頸部外科   Vol.79(No.4) 301-306   Apr 2007
Noriaki Takeda
Equilibrium Research   Vol.63(No.1) 1-7   Feb 2004
The neural mismatch hypothesis in the development of motion sickness is widely accepted. Essential to the neural mismatch hypothesis of motion sickness is the neural mismatch signal encoding spatial disorientation.<BR>We examined the neurochemical...
Noriaki Takeda
JOHNS : Journal of Otolaryngology, Head & Neck Surgery   Vol.20 1512-1514   2004
関根 和教, Noriaki Takeda
JOHNS : Journal of Otolaryngology, Head & Neck Surgery   Vol.20 351-354   2004
Noriaki Takeda
Current Therapy   Vol.21 1023-1030   2003
Noriaki Takeda
耳鼻咽喉科診療Q&A   Vol.37 416-417   2003
Noriaki Takeda
耳鼻咽喉科診療Q&A   Vol.37 406-407   2003
Noriaki Takeda, 関根 和教
Otolaryngology-Head and Neck Surgery   Vol.75 145-151   2003
北村 嘉章, 三好 綾子, 村田 有希, 荻野 敏, 福井 裕行, Noriaki Takeda
Journal of Japan Society of Immunology & Allergology in Otolaryngology   Vol.21(No.2) 134-135   2003
Noriaki Takeda
Shikoku Acta Medica   Vol.58(No.6) 284-288   Dec 2002
Noriaki Takeda
頭頸部外科   Vol.12(No.2) 53-56   Oct 2002
Changes in Fos expression in the rat brainstem after bilateral labyrinthectomy
Acta Otolavyngol   1221, 620-626    2002
Magnetic cortical responses evoked by visual linear forward acceleration
Neuro Report   131, 1805-1808    2002
Noriaki Takeda
Journal of Japan Society for Head and Neck Surgery   Vol.12 53-56   2002
Noriaki Takeda
Medicina   Vol.39 1002-1003   2002
Noriaki Takeda
Medicine and Drug Journal   Vol.37(No.9) 134-137   Sep 2001
Noriaki Takeda, Masahiro Morita, Arata Horii, Suetaka Nishiike, Tadashi Kitahara, Atsuhiko Uno
J.Med.Invest.   Vol.48(No.1,2) 44-59   Feb 2001
Three kinds of neurotransmitters: histamine, acetylcholine and noradrenaline, play important roles in the neural processes of motion sickness, because antihistamines, scopolamine and amphetamine are effective in preventing motion sickness. Histami...
Noriaki Takeda, 宇野 敦彦, 堀井 新
Clinical Neuroscience   Vol.94 1176-1178   2001
Noriaki Takeda, 北原 糺
JOHNS : Journal of Otolaryngology, Head & Neck Surgery   Vol.17 831-834   2001
Noriaki Takeda
The Journal of Therapy   Vol.83 1941-1945   2001
Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.94 963-976   2001
Noriaki Takeda
レジデントノート   Vol.3 68-72   2001
Noriaki Takeda, 荻野 仁
Otolaryngology-Head and Neck Surgery   Vol.73 819-821   2001
Noriaki Takeda
脳   Vol.214 46-50   2001
Noriaki Takeda
ENTONI   Vol.3 9-12   2001
Noriaki Takeda
Otology Japan   Vol.10(No.3) 147-149   Jul 2000
For the treatment of patients with Meniere's disease in the acute period, randomized controlled trials showed that anti-vertigo drugs, such as diphenidol and betahistine, are significantly effective. In the chronic period, Meniere's disease is spe...
Noriaki Takeda
Shikoku Acta Medica   Vol.56 132-135   2000
Noriaki Takeda
Clinical Neuroscience   Vol.18 768-770   2000
Noriaki Takeda
Otolaryngology-Head and Neck Surgery   Vol.72 873-878   2000
Noriaki Takeda
JOHNS : Journal of Otolaryngology, Head & Neck Surgery   Vol.16 1311-1313   2000
Noriaki Takeda
Clinic all-round   Vol.49 1801-1804   2000
Noriaki Takeda
Equilibrium Research   Vol.59 93-102   2000
Noriaki Takeda
Practica Oto-Rhino-Laryngologica   Vol.92 106-107   Jan 1999
Molecular mechanisms of vestibular compensation in the central vestibular system.
acta otolarygol.   Suppl.539 15-18   1998
Noriaki Takeda
Medicine and Drug Journal   Vol.35 109-111   1998
Noriaki Takeda, 久保 武
日耳鼻専門医通信   Vol.56 6-7   1998
Noriaki Takeda
Journal of Clinical and Experimental Medicine   Vol.184 980-980   1998

Books etc

Izumi Chida, Koichi Tamura, Noriaki Takeda
KANEHARA & CO., LTD.   2017   
Noriaki Takeda
IGAKU-SHOIN Ltd.Tokyo,Japan   2017   
Noriaki Takeda
Japan Medkal Journal   2017   
Yoshiaki Kitamura, Noriaki Takeda
株式会社 最新医学社   2017   
Gou Satou, Noriaki Takeda
KANEHARA & CO., LTD.   2017   
Molecular pharmacology of (-)maackiain, from Kujin, an anti-allergic Kampo medicine
Hiroyuki Fukui, Hiroyuki Mizuguchi, Yoshiki Kashiwada, Hisao Nemoto, Yoshiaki Kitamura, Noriaki Takeda
The Japanese Pharmacological Society   Mar 2016   
Clinical significance of histamine H1 receptor gene expression and drug action of antihistamines.
Hiroyuki Fukui, Hiroyuki Mizuguchi, Yoshiaki Kitamura, Noriaki Takeda
Springer Science, NewYork   2016   
Histamine H1 receptor gene expression and drug action of antihistamines.
Hiroyuki Fukui, Hiroyuki Mizuguchi, Hisao Nemoto, Yoshiaki Kitamura, Yoshiki Kashiwada, Noriaki Takeda
Springer Science, NewYork   2016   
Noriaki Takeda
バリューメディカル   Aug 2015   
Noriaki Takeda
IGAKU-SHOIN Ltd.Tokyo,Japan   2013   
Noriaki Takeda
Nakayama-Shoten Co., Ltd.   May 2011   
Noriaki Takeda
全日本病院出版会   Apr 2011   
Noriaki Takeda
Apr 2011   
Noriaki Takeda
IGAKU-SHOIN Ltd.Tokyo,Japan   2010   
Noriaki Takeda, 北原 糺, 宇野 敦彦
May 2009   
Noriaki Takeda
NANZANDO Co.,Ltd.   Mar 2007   
Approaches to Dizzy Patients without Apparent Vestibular Dysfunction
Noriaki Takeda
The Society of Practical Otolaryngology   Jul 2005   
Noriaki Takeda
Nakayama-Shoten Co., Ltd.   May 2005   
Noriaki Takeda
Virtual realityを用いた動揺病研究
西池 季隆, Hironori Akizuki, Seizo Oyama, 渡邉 洋, 松岡 克典, Noriaki Takeda
Tsukasa Takaoka, Noriaki Takeda
Noriaki Takeda
Noriaki Takeda
Noriaki Takeda
耳鼻咽喉科診療プラクティス 第13巻 耳鼻咽喉科・頭頚部外科領域の外傷と異物
Noriaki Takeda, 西池 季隆
文光堂   Oct 2004   
耳鼻咽喉科・頭頸部外科クリニカルトレンド Part4
Noriaki Takeda
Nakayama-Shoten Co., Ltd.   Aug 2004   
大野 浩司, Noriaki Takeda
KINPODO, INC.   Jun 2004   
Noriaki Takeda
IGAKU-SHOIN Ltd.Tokyo,Japan   2004   
ダイナミックメディシン 第1巻
Noriaki Takeda
西村書店   Jun 2003   
耳鼻咽喉科診療プラクティス 第12巻 嗅覚・味覚障害の臨床最前線
Noriaki Takeda
文光堂   May 2003   
Noriaki Takeda
KANEHARA & CO., LTD.   May 2003   
今日の耳鼻咽喉科頭頸部外科治療指針 第2版
Noriaki Takeda
IGAKU-SHOIN Ltd.Tokyo,Japan   May 2003   
Clinical Immunology and allergy in Medicine
S Ogino, Noriaki Takeda, T Harada
JGC Editions   2003   
看護のための最新医学講座 第21巻 耳鼻咽喉科疾患
Noriaki Takeda
Nakayama-Shoten Co., Ltd.   Feb 2002   
耳鼻咽喉科診療プラクティス 第6巻 EBMに基づくめまいの診断と治療
Noriaki Takeda
文光堂   Nov 2001   
CLIENT21 -21世紀耳鼻咽喉科領域の臨床 5 内耳・内耳道
Noriaki Takeda
Nakayama-Shoten Co., Ltd.   May 2001   
別冊「医学のあゆみ」 ヒスタミン研究の最近の進歩
Noriaki Takeda
Ishiyaku Publishers,Inc.   Jul 2000   
新図説臨床耳鼻咽喉科・頭頚部外科講座 第1巻 内耳
Noriaki Takeda
MEDICAL VIEW CO., LTD.   Apr 2000   
CLIENT21 -21世紀耳鼻咽喉科領域の臨床 8 めまい・平衡障害
Noriaki Takeda
Nakayama-Shoten Co., Ltd.   Dec 1999   
Noriaki Takeda
文光堂   Oct 1999   
NEW 耳鼻咽喉科・頭頚部外科学
Noriaki Takeda
Nankodo   Jul 1999   
Noriaki Takeda
KINPODO, INC.   1998   
耳鼻咽喉科・頭頚部外科クリニカルトレンド Part 2
Noriaki Takeda
Nakayama-Shoten Co., Ltd.   1998   
Progress in Allergy and Clinical Immunology
Noriaki Takeda
Hogrefe & Huber Publishers   Jul 1997   
Disorders of the Vestibular System
Noriaki Takeda, Toru Matsunaga
Oxford University Press   Jan 1996   
Neurochemical basis of motion sickness and its treatment and prevention.
Disorders of the Vestibular System, Oxford University Press   1996   
分子神経科学の最先端 ー分子から病態ー
Noriaki Takeda
厚生社   Apr 1995   
Histaminergic Neurons: Morphology and Function
Toru Matsunaga, Noriaki Takeda
CRC Press   Feb 1991   
松永 亨, Noriaki Takeda
厚生社   Jun 1987   
Monoaminergic Neurons: Light Microscopy and Ultrastructure
Noriaki Takeda, Toru Matsunaga
John Wiley & Sons, Inc.   1987   

Research Grants & Projects

Grants-in-Aid for Scientific Research
Project Year: Apr 2017 - Mar 2020    Investigator(s): 近藤 英司
Grants-in-Aid for Scientific Research
Project Year: Apr 2016 - Mar 2019    Investigator(s): 武田 憲昭
Grants-in-Aid for Scientific Research
Project Year: Apr 2016 - Mar 2019    Investigator(s): 佐藤 豪
Grants-in-Aid for Scientific Research
Project Year: Apr 2016 - Mar 2019    Investigator(s): 北村 嘉章
Grants-in-Aid for Scientific Research
Project Year: Apr 2013 - Mar 2016    Investigator(s): TAKEDA Noriaki
Grants-in-Aid for Scientific Research
Project Year: Apr 2012 - Mar 2014    Investigator(s): FUKUI Hiroyuki
Grants-in-Aid for Scientific Research
Project Year: Apr 2009 - Mar 2012    Investigator(s): TAKEDA Noriaki
Grants-in-Aid for Scientific Research
Project Year: Apr 2007 - Mar 2009    Investigator(s): TAKEDA Noriaki
Grants-in-Aid for Scientific Research
Project Year: Apr 2006 - Mar 2009    Investigator(s): FUKUI Hiroyuki
Grants-in-Aid for Scientific Research
Project Year: Apr 2006 - Mar 2009    Investigator(s): YAMAMOTO Shigeru
Grants-in-Aid for Scientific Research
Project Year: Apr 2006 - Mar 2008    Investigator(s): SUETAKA Nishiike
Grants-in-Aid for Scientific Research
Project Year: Apr 2006 - Mar 2008    Investigator(s): 阿部 晃治
Grants-in-Aid for Scientific Research
Project Year: Apr 2005 - Mar 2007    Investigator(s): TAKEDA Noriaki
Grants-in-Aid for Scientific Research
Project Year: Apr 2004 - Mar 2006    Investigator(s): MIYAZAKI Katsushi
Grants-in-Aid for Scientific Research
Project Year: Apr 2003 - Mar 2005    Investigator(s): TAKEDA Noriaki
Grants-in-Aid for Scientific Research
Project Year: Apr 2001 - Mar 2003    Investigator(s): TAKEDA Noriaki
Grants-in-Aid for Scientific Research
Project Year: Apr 1997 - Mar 1999    Investigator(s): TAKEDA Noriaki
Grants-in-Aid for Scientific Research
Project Year: Apr 1996 - Mar 1998    Investigator(s): FURUYAMA Shinobu
Grants-in-Aid for Scientific Research
Project Year: Apr 1994 - Mar 1996    Investigator(s): TAKEDA Noriaki
Grants-in-Aid for Scientific Research
Project Year: Apr 1990 - Mar 1992    Investigator(s): TAKEDA Norikai
Neural mechanisms of motion sickness
Clinical study on vertigo and dizziness
Neurogenic inflammation in nasal allergy


2016-13808 : グルタミン酸を有効成分とする担がん患者の味覚及び/又は食欲障害の改善剤
Rie Tsutsumi, Hiroshi Sakaue, Noriaki Takeda
特許第PCT/JP2016/57701号 : 抗アレルギー剤およびインターロイキン4遺伝子発現抑制剤,ならびにそれらの製造方法および使用方法
内田 勝幸, 木村 勝紀, 溝口 智奈弥, Hiroyuki Fukui, Noriaki Takeda, Yoshiki Kashiwada, Hiroyuki Mizuguchi
特許第2015-048286号 : 抗アレルギー剤およびインターロイキン4遺伝子発現抑制剤,ならびにそれらの製造方法および使用方法
内田 勝幸, 木村 勝紀, 溝口 智奈弥, Hiroyuki Fukui, Noriaki Takeda, Yoshiki Kashiwada, Hiroyuki Mizuguchi
特許第2013-149012号 : 鼻炎の予防治療装置
Noriaki Takeda, Hiroyuki Fukui, Hiroyuki Mizuguchi, 久保 伸夫
特許第2012-040703号 : 鼻過敏症予防・治療剤
Hiroyuki Fukui, Hiroyuki Mizuguchi, Noriaki Takeda
特許第2011-011472号 : 抗アレルギー組成物,抗アレルギー物質セット,及び抗アレルギー物質セットの製造方法
Hiroyuki Fukui, Hiroyuki Mizuguchi, Noriaki Takeda
特許第2010-258476号 : 鼻粘膜検体内部標準遺伝子
Hiroyuki Fukui, Hiroyuki Mizuguchi, Noriaki Takeda
特許第4469987号 : 喉頭咽頭検査治療装置
Noriaki Takeda, 金 昌信
特許第2013-173722号 : 鼻過敏症予防・治療剤
Hiroyuki Fukui, Noriaki Takeda, Hiroyuki Mizuguchi