Masahiro Takagi - My portal

Profile Information

Affiliation: Professor, School of Materials Science, Department of Materials Science, Japan Advanced Institute of Science and Technology

Degree: Doctor of Engineering (1990)(Osaka University)
Master of Engineering (1984)(Osaka University)

J-GLOBAL ID: 200901014545468335
researchmap Member ID: 1000030501

External link: http://www.jaist.ac.jp/ms/labs/takagi/

Research Interests

Research Areas

Manufacturing technology (mechanical, electrical/electronic, chemical engineering) / Applied biofunctional and bioprocess engineering /

Research History

Education

- 1984

Osaka University
- 1984

Graduate School, Division of Engineering, Osaka University
- 1982

School of Engineering, Osaka University
- 1982

Faculty of Engineering, Osaka University

Awards

Papers

269

Effect of temperature on raft-dependent endocytic cluster formation during activation of Jurkat T cells by concanavalin A.

Sharma N, Baek K, Shimokawa N, Takagi M

Journal of bioscience and bioengineering, 127(4) 479-485, Apr, 2019 Peer-reviewed
Effects of Capsaicin on Biomimetic Membranes.

Sharma N, Phan HTT, Yoda T, Shimokawa N, Vestergaard MC, Takagi M

Biomimetics (Basel, Switzerland), 4(1) 17-17, Feb, 2019 Peer-reviewed
Membrane permeation of giant unilamellar vesicles and corneal epithelial cells with lipophilic vitamin nanoemulsions

Miyuki Miyake, Yasushi Kakizawa, Norio Tobori, Masatoshi Kurioka, Nobuhito Tabuchi, Ryo Kon, Naofumi Shimokawa, Yoshio Tsujino, Masahiro Takagi

Colloids and Surfaces B: Biointerfaces, 169 444-452, Sep 1, 2018 Peer-reviewed
Localization of transmembrane multiblock amphiphilic molecules in phase-separated vesicles.

Kinbara K, Umetsu K, Sonobe H, Muraoka T, Shimokawa N, Takagi M

Faraday discussions, 209 315-328, Sep, 2018 Peer-reviewed
Strikingly different effects of cholesterol and 7-ketocholesterol on lipid bilayer-mediated aggregation of amyloid beta (1-42)

Huong T.T. Phan, Naofumi Shimokawa, Neha Sharma, Masahiro Takagi, Mun'delanji C. Vestergaard

Biochemistry and Biophysics Reports, 14 98-103, Jul 1, 2018 Peer-reviewed
Size-dependent uptake of electrically neutral amphipathic polymeric nanoparticles by cell-sized liposomes and an insight into their internalization mechanism in living cells

S. Ichikawa, N. Shimokawa, M. Takagi, Y. Kitayama, T. Takeuchi

Chemical Communications, 54(36) 4557-4560, 2018
Raft-dependent endocytic movement and intracellular cluster formation during T cell activation triggered by concanavalin A

Satomi Yabuuchi, Satoshi Endo, KeangOk Baek, Kunihide Hoshino, Yoshio Tsujino, Mun'delanji C. Vestergaard, Masahiro Takagi

JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 124(6) 685-693, Dec, 2017 Peer-reviewed
Quantification of Fraglide-1, a New Functional Ingredient, in Vinegars

Aydan H. Yatmazt, Tetsuaki Kinoshita, Akio Miyazato, Masahiro Takagi, Yoshio Tsujino, Fumiaki Beppu, Naohiro Gotoh

JOURNAL OF OLEO SCIENCE, 66(12) 1381-1386, Dec, 2017 Peer-reviewed
Chirality-dependent interaction of D- and L-menthol with biomembrane models

Pooja Gusain, Shinya Ohki, Kunihide Hoshino, Yoshio Tsujino, Naofumi Shimokawa, Masahiro Takagi

Membranes, 7(4), Dec 1, 2017 Peer-reviewed
Thermal stability of phase-separated domains in multicomponent lipid membranes with local anesthetics

Ko Sugahara, Naofumi Shimokawa, Masahiro Takagi

Membranes, 7(3), Sep 1, 2017 Peer-reviewed
Development of an ensemble Kalman filter data assimilation system for the Venusian atmosphere

Norihiko Sugimoto, Akira Yamazaki, Toru Kouyama, Hiroki Kashimura, Takeshi Enomoto, Masahiro Takagi

SCIENTIFIC REPORTS, 7(1) 9321, Aug, 2017 Peer-reviewed
Glycosyl chains and 25-hydroxycholesterol contribute to the intracellular transport of amyloid beta (A beta-42) in Jurkat T cells

Neha Sharma, KeangOk Baek, Huong T. T. Phan, Naofumi Shimokawa, Masahiro Takagi

FEBS OPEN BIO, 7(6) 865-876, Jun, 2017 Peer-reviewed
Formation of modulated phases and domain rigidification in fatty acid-containing lipid membranes

Naofumi Shimokawa, Rieko Mukai, Mariko Nagata, Masahiro Takagi

PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 19(20) 13252-13263, May, 2017 Peer-reviewed
Sustained acceleration of soil carbon decomposition observed in a 6-year warming experiment in a warm-temperate forest in southern Japan

Munemasa Teramoto, Naishen Liang, Masahiro Takagi, Jiye Zeng, John Grace

SCIENTIFIC REPORTS, 6 35563, Oct, 2016 Peer-reviewed
Phase Diagrams and Ordering in Charged Membranes: Binary Mixtures of Charged and Neutral Lipids

Naofumi Shimokawa, Hiroki Himeno, Tsutomu Hamada, Masahiro Takagi, Shigeyuki Komura, David Andelman

JOURNAL OF PHYSICAL CHEMISTRY B, 120(26) 6358-6367, Jul, 2016 Peer-reviewed
Coupling between pore formation and phase separation in charged lipid membranes

Hiroki Himeno, Hiroaki Ito, Yuji Higuchi, Tsutomu Hamada, Naofumi Shimokawa, Masahiro Takagi

PHYSICAL REVIEW E, 92(6) 062713, Dec, 2015 Peer-reviewed
Destabilization of Phase-separated Structures in Local Anesthetic-containing Model Biomembranes

Ko Sugahara, Naofumi Shimokawa, Masahiro Takagi

CHEMISTRY LETTERS, 44(11) 1604-1606, Nov, 2015
Molecular behavior of DNA in a cell-sized compartment coated by lipids

Tsutomu Hamada, Rie Fujimoto, Shunsuke F. Shimobayashi, Masatoshi Ichikawa, Masahiro Takagi

Physical Review E - Statistical, Nonlinear, and Soft Matter Physics, 91(6) 062717, Jun 29, 2015 Peer-reviewed
Editor's note

Masahiro Takagi

Seibutsu-kogaku Kaishi, 93 774-777, Jan 1, 2015
Physical properties of the hybrid lipid POPC on micrometer-sized domains in mixed lipid membranes

Naofumi Shimokawa, Mariko Nagata, Masahiro Takagi

PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 17(32) 20882-20888, 2015 Peer-reviewed

Misc.

生体模倣膜を用いた界面活性剤刺激性評価法

下川直史, 高木昌宏

繊維機械学会誌 : せんい, 71(8) 527-531, Aug, 2018
Effect of fatty acids on phase-separation of cell-mimetic membrane

下川直史, 高木昌宏

生体の科学, 69(3) 218-222, May, 2018
Phase separation induced by addition of polyamine in charged lipid membranes

Hikichi Keita, Yamamoto Yogo, Shimokawa Naofumi, Takagi Masahiro

Meeting Abstracts of the Physical Society of Japan, 73 3103-3103, 2018
Phase separation dependent on ionization of phosphatidylserine in binary lipid membranes

Jingyu Guo, Shimokawa Naofumi, Takagi Masahiro

Meeting Abstracts of the Physical Society of Japan, 73 3102-3102, 2018
Phase separation in saturated fatty acids-containing mixed lipid membranes

Shimokawa Naofumi, Masuta Aiko, Nagata Mariko, Shoji Fusae, Mukai Rieko, Takagi Masahiro

Meeting Abstracts of the Physical Society of Japan, 73 3101-3101, 2018
Phase separation by addition of polyvalent cation in negatively charged lipid membranes

Furuta Kazumu, Shimokawa Naofumi, Takagi Masahiro

Meeting Abstracts of the Physical Society of Japan, 72 3282-3282, 2017
Rigidification of phase-separated domain in saturated fatty acid-containing lipid membranes

Shimokawa Naofumi, Ooi Katsuhito, Mukai Rieko, Nagata Mariko, Takagi Masahiro

Meeting Abstracts of the Physical Society of Japan, 72 3283-3283, 2017
Control of phase-separated structure by adding fatty acid in lipid membranes

Shimokawa Naofumi, Mukai Rieko, Nagata Mariko, Takagi Masahiro

Meeting Abstracts of the Physical Society of Japan, 71 2998-2998, 2016
22aPS-102 Domain formation in mixed lipid membranes containing fatty acids

Shimokawa N, Mukai R, Nagata M, Takagi M

Meeting Abstracts of the Physical Society of Japan, 71, 2016
22aPS-103 Phase separation of inner leaflet in asymmetric charged lipid bilayers

Kimata A, Shimokawa N, Takagi M

Meeting Abstracts of the Physical Society of Japan, 71, 2016
22aPS-104 Analysis for fusion of lipid emulsions by electric field

Sasaki H, Shimokawa N, Takagi M

Meeting Abstracts of the Physical Society of Japan, 71, 2016
3P-236 Effect of temperature on lipid raft and cytoskeleton of T-cell

Okubo Yufu, Yabuuchi Satomi, Baek KeangOk, Hoshino Kunihide, Tujino Yoshio, Shimokawa Naohumi, Takagi Masahiro

日本生物工学会大会講演要旨集, 67, 2015
22pPSA-2 Coupling between pore formation and phase separation in charged lipid membranes

Himeno Hiroki, Shimokawa Naofumi, Hamada Tsutomu, Takagi Masahiro

Meeting Abstracts of the Physical Society of Japan, 70, 2015
22pPSA-3 Phase behaviors in charged lipid membranes with coupling between main transition and electrostatic interaction

Shimokawa N, Himeno H, Hamada T, Takagi M, Komura S, Andelman D

Meeting Abstracts of the Physical Society of Japan, 70, 2015
22pPSA-7 Cholesterol localization in lipid membranes affected by charged lipid and addition of salt

Saida T, Himeno H, Shimokawa N, Takagi M

Meeting Abstracts of the Physical Society of Japan, 70, 2015
17pPSB-21 Asymmetric charged lipid bilayers

Kimata A, Shimokawa N, Takagi M

Meeting Abstracts of the Physical Society of Japan, 70, 2015
18pCT-3 Pattern formation induced by oleic acid on lipid membranes

Shimokawa N, Mukai R, Nagata M, Takagi M

Meeting Abstracts of the Physical Society of Japan, 70, 2015
30aPS-118 Charge-induced phase sepration in lipid membranes

Himeno Hiroki, Shimokawa Naofumi, Hamada Tsutomu, Takagi Masahiro

Meeting Abstracts of the Physical Society of Japan, 69, 2014
30aPS-120 Domain formation in model membranes including hybrid lipid

Shimokawa N, Nagata M, Takagi M

Meeting Abstracts of the Physical Society of Japan, 69, 2014
7pAQ-7 Coupling between pore formation and phase separation in charged lipid membranes

Himeno Hiroki, Shimokawa Naofumi, Hamada Tsutomu, Takagi Masahiro

Meeting Abstracts of the Physical Society of Japan, 69, 2014

Books and Other Publications

微生物利用の大展開（今中忠行編）

シー・エム・シー, 2002
Studies on a thermostable chitinase from hyperthermophilic archaea, Pyrococcus kodakaraenis KOD1. In Genetics, Biochemistry and Ecology of Cellulose Degradation.

UNI Publishers Co. Ltd. Tokyo Japan, 1999
Structure and function of Clostridium cellulovorans cellulase subunits. In Environment, Science and Technology : The Challenge of the 21st Century

Chulabhorn Research Institute, Bangkok, Thilond, 1999
Strong and specific peroxidase activity with an antibody L-chain-porphyrin Fe(III) conplex.

Antibody Expression and Engineering, 1995
微生物工学

丸善, 1993
生物工学実験書「生物化学工学実験」4章5章

培風館, 1992
極限環境微生物ハンドブック第1章2節4節(大島泰郎監修)

サイエンスフォーラム, 1991
生命分子工学第3章(三浦謹一郎編)

裳華房, 1990
タンパク質工学における遺伝子制御三浦謹一郎編

講談社サイエンティフィック, 1990
バイオテクノロジーレビュー'88(枯草菌)

シーエムシー, 1988

Presentations

サイクロデキストリン代謝に関する研究

高木昌宏

アメリカ微生物学会総会, May 26, 2001 Invited
重金属毒性に関する研究

高木昌宏

国際環境バイオテクノロジー学会, Jun 17, 2000 Invited
光水素発生に関する研究

高木昌宏

ハラタマ記念国際会議, Jun 9, 2000 Invited
細胞分裂タンパク質に関する研究

高木昌宏

アメリカ微生物学会総会, May 22, 2000 Invited

Teaching Experience

Professional Memberships

Works

Research Projects

Visualization and evaluation of physiological responses by membrane dynamics

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2020 - Mar, 2023
International research development of thermal biology

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Nov, 2015 - Mar, 2021

Tominaga Makoto
Physics, Mathematics and chemistry about control of dynamics in biomimetic and cell-mimetic membrane

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2020

TAKAGI MASAHIRO
Clarification of mechanisms for thermosensation with TRP channels and membrane lipids

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Jun, 2015 - Mar, 2020

TOMINAGA Makoto
Analysis,design and control of 2D and 3D dynamics of cell mimetic membrane

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

Takagi Masahiro, SHIMOKAWA Naofumi, HAMADA Tsutomu
Development of an alternative method to animal test for evaluation of skin-irritation

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2015

TAKAGI Masahiro
Analysis and control of membrane raft dynamics.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2011 - Mar, 2014

TAKAGI MASAHIRO, HAMADA Tsutomu
膜エネルギー変化の制御と機能界面デザイン

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2011 - Mar, 2013

高木昌宏
Dynamics of giant liposomes and cellular signal tranduction

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2008 - 2010

TAKAGI Masahiro, HAMADA Tsutomu
膜ミクロドメイン構造との相互作用によるアミロイド形成機構

科学研究費助成事業, 特定領域研究, 日本学術振興会, 2008 - 2009

高木昌宏
細胞膜の動的構造変化とタンパク質相互作用に関する研究

科学研究費助成事業, 特別研究員奨励費, 日本学術振興会, 2008 - 2009

高木昌宏, VESTERGAARD C.M., VESTERGAARD C. M.
Development of tools for analysis of comprehensive signals of subcellular biomolecules

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Priority Areas, Japan Society for the Promotion of Science, 2005 - 2008

UEDA Mitsuyoshi, TAKAGI Masahiro, KONDO Akihiko, YOSHIDA Kazuya, NAKAYAMA Hideki, FUKUSAKI Eiiciro, ITO Yoshihiro
Dynamics of protein structure alteration at single molecular level

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2005 - 2007

TAKAGI Masahiro, HOSAKA Takahiro
Studies about protein structural alteration switching using in vivo mimic system.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2002 - 2004

TAKAGI Masahiro, SHIRAKI Kentaro
外的環境制御によるタンパク質の非共有結合性自己集積線維構造への誘導

科学研究費助成事業, 特定領域研究, 日本学術振興会, 2002 - 2003

高木昌宏, 白木賢太郎
ファイトケラチン合成酵素の構造及び機能解析

科学研究費助成事業, 特定領域研究, 日本学術振興会, 2001 - 2002

日び隆雄, 黒川洋一, 高木昌宏, 小田順一
Topological mapping of unknown proteins using fluorescent probes

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2000 - 2002

FUKUI Kiichi
魚類性決定過程を利用した内分泌撹乱物質のリスク評価

科学研究費助成事業, 特定領域研究(A), 日本学術振興会, 2001 - 2001

高木昌宏, 田丸浩
Studies on molecular recognition mechanisms of biomolecules and their application

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Priority Areas (A), Japan Society for the Promotion of Science, 1998 - 2001

IMANAKA Tadayuki, TAKAGI Masahiro, SODE Koji, OHTAKE Hisao
タンパク質フォールディング

2001