2009年5月
Enantioselective Conjugate Addition of a Lithium Ester Enolate Catalyzed by Chiral Lithium Amides: A Possible Intermediate Characterized
ORGANIC LETTERS
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- 巻
- 11
- 号
- 9
- 開始ページ
- 1907
- 終了ページ
- 1910
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1021/ol900275y
- 出版者・発行元
- AMER CHEMICAL SOC
Two 1:1 noncovalent mixed aggregates between a lithium enolate and two diastereomeric lithium amides have been identified spectroscopically in THE The NMR data, as well as DFT theoretical calculations, shine some light on a puzzling reversal of induction, observed when switching from one diastereomer of the amide to the other in the enantioselective Michael addition of the lithium enolate to an unsaturated ester.
- リンク情報
- ID情報
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- DOI : 10.1021/ol900275y
- ISSN : 1523-7060
- Web of Science ID : WOS:000265529000011