INOUE Hirokazu

J-GLOBAL         Last updated: Nov 28, 2019 at 14:19
 
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Name
INOUE Hirokazu
URL
http://www.shiga-med.ac.jp/~hqmicro/
Affiliation
Shiga University of Medical Science
Section
Undergraduate School of Medicine, Faculty of Medicine, Shiga University of Medical Science Undergraduate School of Medicine Faculty of Medicine
Job title
Associate Professor

Research Areas

 
 

Academic & Professional Experience

 
1994
 - 
2000
Osaka University, Research Associate
 
1992
 - 
1994
The Rockefeller University, Postdoctral Associate
 
1985
 - 
1991
Osaka University, Research Associate
 
1984
 - 
1985
Special Postdoctoral Fellow(Japanese Association of Science)
 

Education

 
 
 - 
1984
Graduate School, Division of Medicine, Osaka University
 

Published Papers

 
Antitumor activity of potent pyruvate dehydrogenase kinase 4 inhibitors from plants in pancreatic cancer.
Tambe, Y., Terado, T., Kim, C. J., Mukaisho, K., Yoshida, S., Sugihara, H., Tanaka, H., Chida, J., Kido, H., Yamaji, K., Yamamoto, T., Nakano, H., Omura, S. and Inoue, H.
Mol. Carinog.   58(10) 1726-1736   2019   [Refereed]
Anti-oncogenic activities of cyclin D1b siRNA on human bladder cancer cells via induction of apoptosis and suppression of cancer cell stemness and invasiveness.
Kim, C. J., Terado, T., Tambe, Y., Mukaisho, K., Suguhara, H., Kawauchi, A., Inoue, H.
International Journal of Oncology   52 231-240   2018   [Refereed]
Transplantation of iPS-derived tumor cells with a homozygous MHC haplotype induces GRP94 antibody production in MHC-matched macaques.
Ishigaki, H., Maeda, T., Inoue, H., Akagi, T., Sasamura, T., Ishida, H., Inubushi, T., Okahara, J., Shiina, T., Nakamura, M., Otoh, Y., Ogasawara, K.
Cancer Res.   77(21) 6001-6010   2017   [Refereed]
Periostin suppresses in vitro invasiveness via PDK1/Akt/mTOR signaling pathway in a orthotopic model of bladder cancer.
Kim, C. J., Tambe, Y., Mukaisho, K., Sugihara, H., Kageyama, S., Kawauchi, A., Inoue, H.
Oncology Letters   13 4247-4287   2017   [Refereed]
Kim, C. J., Tambe, Y., Mukaisho, K., Sugihara, H., Kawauchi, A., Inoue, H.
Oncology Letters   12 4850-4856   2016   [Refereed]
Kim CJ, Tambe Y, Mukaisho K, Sugihara H, Isono T, Sonoda H, Shimizu T, Kondoh G, Inoue H
Carcinogenesis   35(1) 227-236   2014   [Refereed]
The drs tumor suppressor regulates glucose metabolism via lactate dehydrogenase-B
Tambe Y, Hasebe M, Kim CJ, Inoue H
Mol Carcinog   in press   2014
Tambe Y, Okuyama N, Nakagawa T, Muramoto A, Hasebe M, Chano T, Inoue H.
Cancer Letters   314 82-91   2012   [Refereed]
Ochi Y, Chano T, Ikebuchi K, Inoue H, Isono T, Arai A, Tameno H, Shimada T, Hisa Y, Okabe H.
Oncol Rep   26(4) 805-812   2011   [Refereed]
Kim CJ, Sakamoto K, Tambe Y, Inoue H
Int J Oncol   38 1759-1766   2011   [Refereed]
Chano T, Ikebuchi K, Tomita, Y, Jin Y, Inaji H, Ishitobi M, Teramoto K, Ochi Y, Tameno H, Nishimura I, Minami K, Inoue H, Isono T, Saitoh M, Shimada T, Hisa Y, Okabe H.
PLos ONE   5(12) e15737   2010   [Refereed]
Chano T, Ikebuchi K, Ochi Y, Tameno H, Tomita Y, Jin Y, Inaji H, Ishitobi M, Teramoto K, Nishimura I, Minami K, Inoue H, Isono T, Saitoh M, Shimada T, Hisa Y, Okabe H.
PLoS ONE   5(6) e11404   2010   [Refereed]
Isono T, Kim CJ, Ando Y, Sakurai H, Okada Y, Inoue H
Int. J. Oncol.   35 425-432   2009   [Refereed]
Tambe Y, Yamamoto A, Isono T, Chano T, Fukuda A, Inoue H
Cancer Letters   283 74-83   2009   [Refereed]
Kim CJ, Nishi K, Isono T, Okuyama Y, Tambe Y, Okada Y, Inoue H
Molecular Carcinogenesis   48 953-964   2009   [Refereed]
Shimakage M, Kodama K, Kawahara K, Kim CJ, Ikeda Y, Yutsudo M, Inoue H
Oncol. Rep.   21 1367-1372   2009   [Refereed]
Nishi K, Inoue H, Schnier J B, Rice R H
J. Cell. Biochem. (IF:3.381)   106 63-72   2009   [Refereed]
Role of alternative splicing of periostin in human bladder carcinogenesis.
Kim CJ, Isono T, Tambe Y, Chano T, Okabe H, Okada Y, Inoue H.
Int. J. Oncol.   32 161-169   2008   [Refereed]
GADD34 inhibits mammalian target of rapamycin signaling via tuberous sclerosis complex and controls cell survival under bioenergetic stress.
Watanabe R, Tambe Y, Inoue H, Isono T, Haneda M, Isobe K, Kobayashi T, Hino O, Okabe H, Chano T.
Int. J. Mol. Med.   19(3) 475-483   2007   [Refereed]
Minami K, Tambe Y, Watanabe R, Isono T, Haneda M, Isobe K, Kobayashi K, Hino O, Okabe H, Chano T, Inoue H
J. Virol.   81(20) 11106-11115   2007   [Refereed]
GADD34 induces p21 expression and cellular senescence.
Minami K, Inoue H, Terashita T, Kawakami T, Watanabe R, Haneda M, Isobe K, Okabe H, Chano T
Oncol. Rep.   7 1481-1485   2007   [Refereed]
Down-regulation of drs mRNA is associated with the progression of adult T-cell leukemia/lymphoma.
Shimakage M, Inoue N, Oshima K, Kawahara K, Yamamoto N, Oka T, Tambe Y, Yasui K, Matsumoto K, Yutsudo M, Inoue H.
Int. J. Oncol.   30 1343-1348   2007   [Refereed]
Tambe Y, Yoshioka-Yamashita A, Mukaisho K, Haraguchi S, Chano T, Isono T, Kawai T, Suzuki Y, Kushima R, Hattori T, Goto M, Yamada S, Kiso M, Saga Y, Inoue H.
Carcinogenesis   28(4) 777-784   2007   [Refereed]
Kageyama S, Iwaki H, Inoue H, Isono T, Yuasa T, Nogawa M, Maekawa T, Ueda M, Kajita Y, Ogawa O, Toguchida J, Yoshiki T.
Proteomics Clin. Appl.   1(2) 192-199   2007   [Refereed]
Neuromuscular abundance of RB1CC1 contributes to the non-proliferating enlarged cell phenotype through both RB1 maintenance and TSC1 degradation.
Chano T, Saji M, Inoue H, Minami K, Kobayashi T, Hino O, Okabe H
Int. J. Mol. Med.   18 425-432   2006   [Refereed]
Shimakage M, Inoue N, Oshima K, Kawahara K, Oka T, Yasui K, Matsumoto K, Inoue H, Watari A, Higashiyama S., Yutsudo M.
Int. J. Cancer   119 1648-1653   2006   [Refereed]
Kim C. J., Yoshioka N., Tambe Y., Kushima R., Okada Y., Inoue H.
Int. J. Cancer   117 51-58   2005   [Refereed]
Watanabe R, Chano T, Inoue H, Isono T, Koiwai O, Okabe H.
Virchows Arch.   446 643-648   2005   [Refereed]
Suzuki J, Sukezane T, Akagi T, Georgescu MM., Ohtani M, Inoue H, Jat PS., Goff SP., Hanafusa H, Shishido Y
Oncogene   23 8527-8534   2004   [Refereed]
Tambe Y, Isono T, Haraguchi S, Yoshioka-Yamashita A, Yutsudo M, Inoue H
Oncogene   23 2977-2987   2004   [Refereed]
Haraguchi S, Saga Y, Naito K, Inoue H, Seto A
Mol. Reprod. Dev.   68 17-571   2004   [Refereed]
Shimakage M, Kawahara K, Sasagawa T, Inoue H, Yutsudo M, Yoshida M, Yanoma S
Human Pathology   34 1170-1177   2003   [Refereed]
Kim CJ, Shimakage M, Kushima R, Mukaisho K, Shinka T, Okada Y, Inoue H
Human Pathology   34 654-657   2003   [Refereed]
Qi B, Qi Y, Watari A, Yoshioka N, Inoue H, Minemoto Y, Yamashita K, Sasagawa T, Yutsudo M
J. Cell. Physiol.   196 312-318   2003   [Refereed]
Yoshioka N, Fuji S, Shimakage M, Kodama K, Hakura A, Yutusdo M, Inoue H, Nojima H
Exp. Cell Res.   279 91-99   2002   [Refereed]
Shimakage M, Takami K, Kodama K, Mano K, Yutsudo M, Inoue H
Human Pathology   33 615-619   2002   [Refereed]
Kawai T, Suzuki Y, Yamashita A, Inoue H
Cancer Letters   183 79-86   2002   [Refereed]
Down-regulation of drs mRNA in colorectal neoplasms
Mukaisho K, Suo Masashi, Shimakage M, Kushima R, Inoue H, Hattori T
Jpn. J. Cancer Res.   93 888-893   2002   [Refereed]
Li Q, Oka K, Shimakage M, Yoshioka N, Kodama K, Inoue H, Hakura A, Stanbridge EJ, Yutsudo M
Oncogene   20 3929-3926   2001   [Refereed]
Shimakage M, Kawahara K, Kikkawa N, Sasagawa T, Yutsudo M, Inoue H
Int. J. Cancer   87 5-11   2000   [Refereed]
Yoshioka N, Inoue H, Nakanishi K, Oka K, Yutsudo M, Yamashita A, Hakura A, Nojima H
J. Virol.   74 1008-1013   2000   [Refereed]
Yamashita A, Hakura A, Inoue H
Oncogene   18 4777-4787   1999   [Refereed]
Kyo S, Kanaya T, Takakura M, Tanaka M, Yamashita A, Inoue H, Inoue M
Int. J. Cancer   80 804-809   1999   [Refereed]
Suppression of v-Src transformation by the drs gene.
Inoue H, Pan J, Hakura A
J. Virol.   72 2532-2537   1998   [Refereed]
Ishiwatari H, Nakanishi K, Kondoh G, Hayasaka N, Li Q, Yamashita A, Inoue H, Hakura A
Cancer letters   117 57-65   1997   [Refereed]
Human T-cell leukemia virus type I tax protein transforms rat fibroblasts via two distinctive pathways.
Matsumoto K, Fujisawa J, Inoue H, Hakura A, Shibata H, Fujii M
J. Virol.   71 4445-4451   1997   [Refereed]
Tang G, Iida T, Inoue H, Yutsudo M, Yamamoto K, Honda T
Biochim. Biophys. Acta   1360 277-282   1997   [Refereed]
Cellular aging is a critical determinant of primary cell resistance to v-Src transformation.
Tavoloni N, Inoue H
J. Virol.   71 237-247   1997   [Refereed]
Inoue H, Yamashita A, Hakura A
Virology   225 223-226   1996   [Refereed]
Increased sensitivity of EBNA2-transformd rat fibroblasts to ionizing radiation.
Shimakage M, Miyata Y, Inoue H, Yutsudo M, Hakura A
Int. J. Cancer   68 612-615   1996   [Refereed]
Pan J, Nakanishi K, Yutsudo M, Inoue H, Li Q, Oka K, Yoshioka N, Hakura A
FEBS letters   383 21-25   1996   [Refereed]
Shimakage M, Kurata A, Inoue H, Okamoto Y, Yutsudo M, Hakura A
FEBS letters   371 245-248   1995   [Refereed]
Suppression of v-Src transformation in primary rat embryo fibroblast.
Inoue H, Tavoloni N, Hanafusa H
Oncogene   11 231-238   1995   [Refereed]
Tavoloni N., Inoue H., Sabe H., Hanafusa H.
J. Cell Biol.   126 475-483   1994   [Refereed]
Ishiwatari H., Hayasaka N., Inoue H., Yutsudo M., Hakura A.
J. Med. Virol.   44 243-249   1994   [Refereed]
A Ki-1-positive cell line expressing Epstein-Barr virus antigens,established from a child with Ki-1-positeve lymphoma.
Shimakage M, Dezawa T, Tabata T, Aoyagi N, Koike M, Inoue H, Yutsudo M, Hakura A, Ikegami N
Intervirology   36 215-224   1993   [Refereed]
NF-IL6 represses early gene expression of human papillomavirus type 16 through binding to the noncoding region.
Kyo S, Inoue M, Nishio Y, Nakanishi K, Akira S, Inoue H, Yutsudo M, Tanizawa O, Hakura A
J. Virol.   67 1058-1066   1993   [Refereed]
Inoue H, Miyasaka M, Inoue T, Hakura A
Virology   195 757-761   1993   [Refereed]
Induction of uterine cervical neoplasias in mice by human papillomavirus type 16 E6/E7 genes. E/E7 gene.
Sasagawa T, Inoue M, Inoue H, Yutsudo M, Tanizawa O, Hakura A
Cancer Res.   52 4420-4426   1992   [Refereed]
Ishii K, Inoue H, Hakura A, Arai W, Masuda T
Cell Struct. and Funct.   17 197-202   1992   [Refereed]
Isaka M, Inoue H, Tsukiyama T, Niwa O, Hakura A
Virology   189 141-149   1992   [Refereed]
Inoue H, Kondoh G, Sudiro TM., Hakura A
Virology   187 343-347   1992   [Refereed]
Sudiro TM, Inoue H, Yutsudo M, Hakura A
Virology   182 357-360   1991   [Refereed]
Rat embryo fibroblast cells suppress transformation by the E6 and E7 genes of human papillomavirus type 16 in somatic hybrid cells.
Miyasaka M, Takami Y, Inoue H, Hakura A
J. Virol.   65 479-482   1991   [Refereed]
Inoue H, Kondoh G, Kamakura CR, Yutsudo M, Hakura A
Virology   180 191-198   1991   [Refereed]
Simple system for isolation of cellular and viral mutants for transformation by retrovirus
Inoue H, Isaka M, Takeda S, Hakura A
J. Med. Virol.   35 246-249   1991   [Refereed]
Oka Y, Sugiyama H, Tsukada S, Inoue H, Hakura A, Kishimoto S
Cellular Immunology   35 246-249   1990   [Refereed]
Oka T, Yutsudo M, Inoue H, Higuchi F, Hakura A
J. Cell. Physiol.   145 428-433   1990   [Refereed]
Prevalence and typing of human papillomavirus DNA isolated from cervical carcinoma in Korean patients
Kim H, Takami Y, Kim K, Inoue H, Yutsudo M, Hakura A
J. Kor. Soc. Virol.   145 428-433   1990   [Refereed]
A novel monoclonal antibody against squamous cell carcinoma
Inoue M, Nakanishi K, Sasagawa T, Tanizawa O, Inoue H, Hakura A
Jpn. J. Cancer Res.   81 176-182   1990   [Refereed]
Novel non-tumorigenic cell variants showing potentially different susceptibility to v-src-induced metastasis
Enomoto T., Ayaki H., Nakamori S., Enomoto Y., Inoue H., Kakunaga T.
Jpn. J. Cancer Res.   81 501-505   1990   [Refereed]
Isolation and characterization of temperature-sensitive mutants of Abelson murine leukemia virus that exhibit dissociation among morphological transformation, soft agar colony forming ability and tyrosine kinase activity
Oka Y, Sugiyama H, Tsukada S, Shimizu Y, Inoue H, Hakura A, Kishimoto S
J. Gen. Virol.   70 2527-2532   1989   [Refereed]
Inoue H, Owada MK, Yutsudo M, Hakura A
Virology   168 57-66   1989   [Refereed]
Temperature-sensitive cellular mutant for expression of mRNA from murine retrovirus
Inoue H, Kizaka S, Yutsudo M, Hakura A
J. Virol.   62 106-113   1988   [Refereed]
Nakayama T, Irikura M, Setoguchi Y, Matsuo H, Inoue H, Yutsudo M, Hakura A
Biochem. Biophys. Res. Commun.   149 1156-1164   1987   [Refereed]

Research Grants & Projects

 
Study on function of host cell genes which suppress viral replication
Project Year: 2005   
Study on novel tumor suppressor genes
Project Year: 1996   
Study on cell transformation by viral oncogenes
Project Year: 1994