TAKEMOTO Yoshiji

J-GLOBAL         Last updated: Jul 3, 2019 at 11:14
 
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Name
TAKEMOTO Yoshiji
Affiliation
Kyoto University
Section
Graduate School of Pharmaceutical Sciences, Division of Physical and Organic Chemistry, Graduate School of Pharmaceutical Sciences
Job title
Professor
Degree
(BLANK)(Osaka University), Doctor of Pharmaceutical Science
ORCID ID
0000-0003-1375-3821

Research Areas

 
 

Academic & Professional Experience

 
1988
 - 
1989
postdoctor, Florida State University
 
1989
 - 
1990
postdoctor, Sagami Chemical Reseach Center
 
1990
 - 
1998
research assistant, Faculty of Pharmaceutical Sciences,
 
 
   
 
      Osaka University
 
1998
 - 
2000
assistant professor, Graduate School
 

Education

 
 
 - 
1988
Graduate School, Division of Pharmaceutical Sciences, Osaka University
 
 
 - 
1983
Faculty of Pharmaceutical Science, Osaka University
 

Awards & Honors

 
1993
Takeda Award in Synthetic Organic Chemistry, Japan
 
1994
The Pharmaceutical Society of Japan Kinki Branch Award for Young Scientists
 

Published Papers

 
Total Synthesis of Caprazamycin A: Practical and Scalable Synthesis of syn-β-Hydroxyamino Acids and Introduction of a Fatty Acid Side Chain to 1,4-Diazepanone
ugh Nakamura, Chihiro Tsukano, Takuma Yoshida, Motohiro Yasui, Shinsuke Yokouchi, Yusuke Kobayashi, Masayuki Igarashi, Yoshiji Takemoto
J. Am. Chem. Soc.   141(21) 8527-8540   May 2019   [Refereed]
Synthesis of the ABCDG ring skeleton of communesin F based on carboborylation of 1,3-diene and Bi(OTf)3-catalyzed cyclizations
Motoyuki Nakajima, Chihiro Tsukano, Motohiro Yasui, Yoshiji Takemoto
The Journal of Antibiotics   72 407-419   Feb 2019   [Refereed]
Regio- and Stereoselective Synthesis of 1,2-cis-Glycosides by Anomeric O-Alkylation with Organoboron Catalysts
Sanae Izumi, Yusuke Kobayashi, Yoshiji Takemoto
Org. Lett.   21(3) 665-670   Jan 2019   [Refereed]
Catalytic asymmetric aza-Michael addition of fumaric monoacids with multifunctional thiourea/boronic acids
Kenichi Michigami, Hiroki Murakami, Takeru Nakamura,† Noboru Hayama, Yoshiji Takemoto
Org. Biomol. Chem.   17(9) 2331-2335   Jan 2019   [Refereed]
Synthesis of cis-/All-cis-Substituted Cyclopropanes through Stereocontrolled Metalation and Pd-Catalyzed Negishi Coupling
Motohiro Yasui, Rina Ota, Chihiro Tsukano, Yoshiji Takemoto
Org. Lett.   20(23) 7656-7660   Nov 2018   [Refereed]
Palladium-catalyzed intramolecular carboborylation of 1,3-diene and synthesis of ABCD ring of communesins
Chihiro Tsukano, Motoyuki Nakajima, Sudhir M. Hande, Yoshiji Takemoto
Org. Biomol. Chem.   17(7) 1731-1735   Oct 2018   [Refereed]
Arylboronic Acid-Mediated Glycosylation of 1,2-Dihydroxyglucoses
Sanae Izumi, Yusuke Kobayashi, Yoshiji Takemoto
Heterocycles   99(1) 350-362   Oct 2018   [Refereed]
Mechanistic Insight into Asymmetric Hetero-Michael Addition of α,β-Unsaturated Carboxylic Acids Catalyzed by Multifunctional Thioureas
Noboru Hayama, Ryuta Kuramoto, Tamás Földes, Kazuya Nishibayashi, Yusuke Kobayashi, Imre Pápai, Yoshiji Takemoto
J. Am. Chem. Soc.   140(38) 12216-12225   Sep 2018   [Refereed]
Oxidative Decarboxylation Enables Chemoselective, Racemization-Free Esterification: Coupling of α-Ketoacids and Alcohols Mediated by Hypervalent Iodine(Ⅲ)
Takeshi Nanjo, Natsuki Kato, Yoshiji Takemoto
Org. Lett.   20(18) 5766-5769   Aug 2018   [Refereed]
Silyl enol etherification by a Tf2NH/amine co-catalytic system for minimizing hazardous waste generation
Kei Kurahashi, Yousuke Yamaoka, Yoshiji Takemoto, Kiyosei Takasu
React. Chem. Eng.   3 626-630   Jul 2018   [Refereed]
Organocatalytic Direct α-Selective N-Glycosylation of Amide with Glycosyl Trichloroacetimidate
Shanji Li, Yusuke Kobayashi, Yoshiji Takemoto
Chem. Pharm. Bull.   66(7) 768-770   Jul 2018   [Refereed]
Photo-induced aziridination of alkenes with N-sulfonyliminoiodinanes
Sota Masakado, Yusuke Kobayashi, Yoshiji Takemoto
Chem. Pharm. Bull.   66(6) 688-690   Jun 2018   [Refereed]
Concise Synthesis of (±)-Aurantioclavine
Hideo Ikota, Chihiro Tsukano, Yoshiji Takemoto
Heterocycles   97(1) 621-631   Apr 2018   [Refereed][Invited]
Yusuke Kobayashi, Yuya Nakatsuji, Shanji Li, Seiji Tsuzuki, Yoshiji Takemoto
Angew. Chem. Int. Ed.   57(14) 3646-3650   Feb 2018   [Refereed]
Chihiro Tsukano, Satoshi Suetsugu, Nubusuke Muto, Yoshiji Takemoto
Chem. Pharm. Bull.   65(12) 1167-1174   Dec 2017   [Refereed]
Yusuke Kobayashi, Sota Masakado, Yoshiji Takemoto
Angew. Chem. Int. Ed.   57(3) 693-697   Dec 2017   [Refereed]
Tomohiro Kurose, Chihiro Tsukano, Yoshiji Takemoto
Org. Lett.   19(18) 4762-4765   Sep 2017   [Refereed]
Total Synthesis of Avenaol
Motohiro Yasui, Rina Ota, Chihiro Tsukano, Yoshiji Takemoto
Nature Communications   8(674) 1-9   Sep 2017   [Refereed]
Taryn March, Akihiro Murata, Yusuke Kobayashi, Yoshiji Takemoto
Synlett   28(11) 1295-1299   Jun 2017   [Refereed]
Masato Saito, Yusuke Kobayashi, Seiji Tsuzuki, Yoshiji Takemoto
Angew. Chem. Int. Ed.   56(26) 7653-7657   Jun 2017   [Refereed]
Yusuke Kobayashi, Takuma Yoshida, Takuya Uno, Chihiro Tsukano, Yoshiji Takemoto
Heterocycles   95(2) 980-993   Feb 2017   [Refereed]
Le Zhao, Chihiro Tsukano, Eunsang Kwon, Hisashi Shirakawa, Shuji Kaneko, Yoshiji Takemoto, Masahiro Hirama
Chem. Eur. J.   23(4) 802-812   Jan 2017   [Refereed]
Takeshi Nanjo, Chihiro Tsukano, Yoshiji Takemoto
Chem. Pharm. Bull.   64(9) 1384-1392   Sep 2016   [Refereed]
Noboru Hayama, Takumi Azuma, Yusuke Kobayashi, Yoshiji Takemoto
Chem. Pharm. Bull.   64(7) 704-717   Jul 2016   [Refereed]
Eito Yoshioka, Shigeru Kohtani, Takahisa Jichu, Takuya Fukazawa, Toyokazu Nagai, Akira Kawashima, Yoshiji Takemoto, Hideto Miyabe
J. Org. Chem.   81(16) 7217-7229   Jun 2016   [Refereed]
Satoshi Suetsugu, Nobusuke Muto, Misa Horinouchi, ChihiroTsukano, Yoshiji Takemoto
Chem. Eur. J.   22(24) 8059-8062   May 2016   [Refereed]
Hugh Nakamura, Takuma Yoshida, Chihiro Tsukano, Yoshiji Takemoto
Org. Lett.   18(9) 2300-2303   Apr 2016   [Refereed]
Hongyan Xiao, Yusuke Kobayashi, Yoshiji Takemoto, Keiji Morokuma
ACS Catal.   6(5) 2988-2996   Apr 2016   [Refereed]
Catalytic Asymmetric Synthesis of anti-α,β-Diamino Acid Derivatives
Sanae Izumi, Yusuke Kobayashi, Yoshiji Takemoto
Org. Lett.   18(4) 696-699   Feb 2016   [Refereed]
Satoshi Suetsugu, Chihiro Tsukano, Yoshiji Takemoto
Eur. J. Org. Chem.   (1) 108-115   Jan 2016   [Refereed]
Yusuke Kobayashi, Ryuta Kuramoto, Yoshiji Takemoto
Beilstein J. Org. Chem   11 2654-2660   Dec 2015   [Refereed]
Chihiro Tsukano, Sho Yamamoto, Yoshiji Takemoto
Chem. Pharm. Bull.   63(9) 710-719   Sep 2015   [Refereed]
Masato Saito, Nobuya Tsuji, Yusuke Kobayashi, Yoshiji Takemoto
Org. Lett.   17(12) 3000-3003   May 2015   [Refereed]
Yoshioka, E.; Kohtani, S.; Jichu, T.; Fukazawa, T.; Nagai, T.; Takemoto, Y.; Miyabe, H.
Synlett   26(2) 265-270   Jan 2015   [Refereed]
Nakamura, H.; Tsukano, C.; Yasui, M.; Yokouchi, S.; Igarashi, M.; Takemoto, Y.
Angewandte Chemie International Edition   54(10) 3136-3139   Jan 2015   [Refereed]
Arichi, N.; Hata, K.; Takemoto, Y.; Yamada, K.; Yamaoka, Y.; Takasu, K.
Tetrahedron   71(2) 233-244   Jan 2015   [Refereed]
Sakamoto, S.; Kazumi, N.; Kobayashi, Y.; Tsukano, C.; Takemoto, Y.
Organic Letters   16(18) 4758-4761   Sep 2014   [Refereed]
Tsuji, N.; Kobayashi, Y.; Takemoto, Y.
Chemical Communications   50(89) 13691-13694   Sep 2014   [Refereed]
Tsukano, C.; Takemoto, Y.
Heterocycles   89(10) 2271-2302   Sep 2014   [Refereed][Invited]
Tsuji, N.; Stadler, M.; Naoya Kazumi; Inokuma, T.; Kobayashi, Y.; Takemoto, Y.
Organic and Biomolecular Chemistry   12(40) 7919-7922   Aug 2014   [Refereed]
Azuma, T.; Murata, A.; Kobayashi, Y.; Inokuma, T.; Takemoto, Y.
Organic Letters   16(16) 4256-4259   Jul 2014   [Refereed]
Tsukano, C.; Muto, N.; Enkhtaivan, I.; Takemoto, Y.
Chemistry, An Asian Journal   9(9) 2628-2634   Jul 2014   [Refereed]
Ikota, H.; Ishida, T.; Tsukano, C.; Takemoto, Y.
Chemical Communications   50(64) 8871-8874   Jun 2014   [Refereed]
Tsukano, C.; Okuno, M.; Nishiguchi, H.; Takemoto, Y.
Advanced Synthesis and Catalysis   356(7) 1533-1538   Apr 2014   [Refereed]
Nanjo, T.; Tsukano, C.; Takemoto, Y.
Synlett   25(10) 1473-1477   Apr 2014   [Refereed]
Hata, K.; Arichi, N.; Yamaoka, Y.; Yamada, K.-i.; Takemoto, Y.; Takasu, K.
Asian Journal of Organic Chemistry   3(6) 706-710   Apr 2014   [Refereed]
Kobayashi, Y.; Li, S.; Takemoto, Y.
Asian Journal of Organic Chemistry   3(4) 403-407   Mar 2014   [Refereed]
Kobayashi, Y.; Suzuki, Y.; Ogata, T.; Kimachi, T.; Takemoto, Y.
Tetrahedron Letters   55(22) 3299-3301   Mar 2014   [Refereed]
Tsukano, C.; Oimura, A.; Enkhtaivan, I.; Takemoto, Y.
Synlett   25(5) 653-656   Feb 2014   [Refereed]
Sasaoka, N.; Sakamoto, M.; Kanemori, S.; Kan, M.; Tsukano, C.; Takemoto, Y.; Kakizuka, A.
PLOS ONE   9(1) e78185   Jan 2014   [Refereed]
T. Azuma; Y. Kobayashi; K. Sakata; T. Sasamori; N. Tokitoh; Y. Takemoto
Journal of Organic Chemistry   79(4) 1805-1817   2014   [Refereed]
S. Suetsugu; H. Nishiguchi; C. Tsukano; Y. Takemoto
Organic Letters   16(3) 996-999   2014   [Refereed]
Y. Nagamoto; Y. Yamaoka; S. Fujimura; Y. Takemoto; K. Takasu
Organic Letters   16(3) 1008-1011   2014   [Refereed]
2. Miyabe, H.; Takemoto, Y.
Universal Organic Chemistry   2(1)    2014   [Refereed]
L. Zhao; C. Tsukano; E. Kwon; Y. Takemoto; M. Hirama
Angewandte Chemie - International Edition   52(6) 1722-1725   2013   [Refereed]
Y. Takemoto; T. Inokuma
Asymmetric Synthesis II: More Methods and Applications   233-237   2013   [Refereed]
Y. Kobayashi; Y. Taniguchi; N. Hayama; T. Inokuma; Y. Takemoto
Angewandte Chemie - International Edition   52(42) 11114-11118   2013   [Refereed]
T. Ishida; H. Ikota; K. Kurahashi; C. Tsukano; Y. Takemoto
Angewandte Chemie - International Edition   52(39) 10204-10207   2013   [Refereed]
Y. Kuroda; N. Shindoh; Y. Takemoto; K. Takasu
Synthesis   45(16) 2328-2329   2013   [Refereed]
T. Nanjo; S. Yamamoto; C. Tsukano; Y. Takemoto
Organic Letters   15(14) 3754-3757   2013   [Refereed]
H. Miyabe; R. Asada; Y. Takemoto
Beilstein Journal of Organic Chemistry   9 1148-1155   2013   [Refereed]
C. Tsukano; M. Okuno; Y. Takemoto
Chemistry Letters   42(7) 753-755   2013   [Refereed]
T. Ishida; Y. Takemoto
Tetrahedron   69(23) 4517-4523   2013   [Refereed]
Y. Nagamoto; A. Hattori; H. Kakeya; Y. Takemoto; K. Takasu
Chemical Communications   49(26) 2622-2624   2013   [Refereed]
Y. Nagamoto; Y. Takemoto; K. Takasu
Synlett   24(1) 120-124   2013   [Refereed]
T. Nanjo; C. Tsukano; Y. Takemoto
Organic Letters   14(16) 4270-4273   Aug 2012   [Refereed]
C. Tsukano; A. Oimura; I. Enkhtaivan; Y. Takemoto
Organic Letters   14(7) 1902-1905   Apr 2012   [Refereed]
Thiourea,N-[3,5-BIS(TRIFLUOROMETHYL)PHENYL] -N-[(1R,2R)-2- (DIMETHYLAMINO)CYCLOHEXYL]-
Takasu, K.; Takemoto, Y.
e-EROS      2012   [Invited]
C. Tsukano; M. Okuno; Y. Takemoto
Angewandte Chemie - International Edition   51(11) 2763-2766   2012   [Refereed]
T. Uno; Y. Kobayashi; Y. Takemoto
Beilstein Journal of Organic Chemistry   8 1499-1504   2012   [Refereed]
C. Tsukano; S. Yokouchi; A.-L. Girard; T. Kuribayashi; S. Sakamoto; T. Enomoto; Y. Takemoto
Organic and Biomolecular Chemistry   10(30) 6074-6086   2012   [Refereed]
T. Inokuma; M. Furukawa; Y. Suzuki; T. Kimachi; Y. Kobayashi; Y. Takemoto
ChemCatChem   4(7) 983-985   2012   [Refereed]
K. Inanaga; Y. Ogawa; Y. Nagamoto; A. Daigaku; H. Tokuyama; Y. Takemoto; K. Takasu
Beilstein Journal of Organic Chemistry   8 658-661   2012   [Refereed]
H. Miyabe; R. Asada; Y. Takemoto
Organic and Biomolecular Chemistry   10(17) 3519-3530   2012   [Refereed]
K. Kurahashi; Y. Takemoto; K. Takasu
ChemSusChem   5(2) 270-273   2012   [Refereed]
T. Uno; T. Inokuma; Y. Takemoto
Chemical Communications   48(13) 1901-1903   2012   [Refereed]
T. Ishida; C. Tsukano; Y. Takemoto
Chemistry Letters   41(1) 44-46   2012   [Refereed]
K. Hirano; Y. Inaba; K. Takasu; S. Oishi; Y. Takemoto; N. Fujii; H. Ohno
Journal of Organic Chemistry   76(21) 9068-9080   Nov 2011   [Refereed]
T. Inokuma; M. Furukawa; T. Uno; Y. Suzuki; K. Yoshida; Y. Yano; K. Matsuzaki; Y. Takemoto
Chemistry - A European Journal   17(37) 10470-10477   Sep 2011   [Refereed]
A.-L. Girard; T. Enomoto; S. Yokouchi; C. Tsukano; Y. Takemoto
Chemistry - An Asian Journal   6(6) 1321-1324   Jun 2011   [Refereed]
S.M. Hande; M. Nakajima; H. Kamisaki; C. Tsukano; Y. Takemoto
Organic Letters   13(7) 1828-1831   Apr 2011   [Refereed]
Effects of bolus injection of 5-fluorouracil on steady-state plasma concentrations of 5-fluorouracil in Japanese patients with advanced colorectal cancer
T. Tamura; A. Kuwahara; K. Kadoyama; M. Yamamori; K. Nishiguchi; T. Inokuma; Y. Takemoto; N. Chayahara; T. Okuno; I. Miki; Y. Fujishima; T. Sakaeda
International Journal of Medical Sciences   8(5) 406-412   2011   [Refereed]
H. Kamisaki; T. Nanjo; C. Tsukano; Y. Takemoto
Chemistry - A European Journal   17(2) 626-633   2011   [Refereed]
S. Sakamoto; T. Inokuma; Y. Takemoto
Organic Letters   13(24) 6374-6377   2011   [Refereed]
T. Inokuma; Y. Suzuki; T. Sakaeda; Y. Takemoto
Chemistry - An Asian Journal   6(11) 2902-2906   2011   [Refereed]
T. Azuma; Y. Takemoto; K. Takasu
Chemical and Pharmaceutical Bulletin   59(9) 1190-1193   2011   [Refereed]
N. Shindoh; K. Kitaura; Y. Takemoto; K. Takasu
Journal of the American Chemical Society   133(22) 8470-8473   2011   [Refereed]
H. Miyabe; K. Moriyama; Y. Takemoto
Chemical and Pharmaceutical Bulletin   59(6) 714-720   2011   [Refereed]
H. Kamisaki; Y. Kobayashi; T. Kimachi; Y. Yasui; Y. Takemoto
Journal of Organometallic Chemistry   696(1) 42-45   2011   [Refereed]
Bromonitromethane
Inokuma, T.; Takemoto, Y.
e-EROS      2010   [Invited]
Y. Takemoto; H. Miyabe
Catalytic Asymmetric Synthesis: Third Edition   227-267   2010   [Refereed]
N. Shindoh; Y. Takemoto; K. Takasu
Heterocycles   82(2) 1133-1136   2010   [Refereed]
K. Takasu; T. Azuma; I. Enkhtaivan; Y. Takemoto
Molecules   15(11) 8327-8348   2010   [Refereed]
K. Takasu; T. Tanaka; T. Azuma; Y. Takemoto
Chemical Communications   46(43) 8246-8248   2010   [Refereed]
C. Tsukano; L. Zhao; Y. Takemoto; M. Hirama
European Journal of Organic Chemistry   (22) 4198-4200   2010   [Refereed]
K. Takasu; Y. Nagamoto; Y. Takemoto
Chemistry - A European Journal   16(28) 8427-8432   2010   [Refereed]
T. Enomoto; Y. Yasui; Y. Takemoto
Journal of Organic Chemistry   75(14) 4876-4879   2010   [Refereed]

Misc

 
Catalytic Dehydrative Peptide Synthesis with gem-Diboronic Acids
〇Michigami Kenichi, Sakaguchi Tatsuhiko, Takemoto Yoshiji
日本化学会第99春季年会      Mar 2019   [Refereed]
Ortho-effect-enabled Characterization of N-Acyliminoiodinane and Its Appication to Photo-induced Amination
○Yusuke Kobayashi, Sota Masakado, Tomohiro Kimura, Yoshiji Takemoto
IKCOC-14      Nov 2018   [Refereed]
Synthetic Studies of Sphaerimicin A, a Liponuleoside Antibiotic
○Chihiro Tsukano, Hugh Nakamura, Takuma Yoshida, Yoshiji Takemoto
The 4th International Symposium on Middle Molecular Strategy (ISMMS-4)      Nov 2018   [Refereed]
Synthesis of (±)-Shagene B
○Chihiro Tsukano, Takayoshi Heike, Kazuya Nishibayashi, Tagwa A. Mohammed, Yoshiji Takemoto
IKCOC-14      Nov 2018   [Refereed]
Synthetic Studies on Fawcettimine-type Lycopodium Alkaloids via Head-Substituted Cyclopropane
○Tomohiro Kurose, Chihiro Tsukano, Yoshiji Takemoto
22nd International Conference on Organic Synthesis      Sep 2018   [Refereed]
Regio- and Stereoselective Synthesis of 1,2-cis-Glycosides by Anomeric O-Alkylation with Organoboron Catalysts
○Sanae Izumi, Yusuke Kobayashi, Yoshiji Takemoto
22nd International Conference on Organic Synthesis      Sep 2018   [Refereed]
Organocatalytic Direct N-Glycosylation of Amides with Glycosyl Trichloroacetimidates
○Yusuke Kobayashi, Yuya Nakatsuji, Shanji Li, Yoshiji Takameoto
International Symposium on Main Group Chemistry Directed towards Organic Synthesis (MACOS)      Aug 2018   [Refereed][Invited]
Design, Synthesis, and Application of Novel N-acyliminoiodinane
Yusuke Kobayashi,〇Sota Masakado, Yoshiji Takemoto,
HALCHEM VIII      Sep 2017   [Refereed]
Competent route to Unsymmetric Dimer Architectures: Total Synthesis of (-)-Lycodine and (-)-Complanadines A and B
〇Chihiro Tsukano, Le Zhao, Eunsang Kwon, Masahiro Hirama, Yoshiji Takemoto
The 26th ISHC Congress      Sep 2017   [Refereed]
〇Masato Saito. Yusuke Kobayashi. Seiji Tsuzuki. and Yoshiji Takemoto
The 26th ISHC Congress      Sep 2017   [Refereed]
First Total Synthesis of Avenaol: A New Strategy for Synthesis of All-cis-Substituted Cyclopropane Natural products
〇Motohiro Yasui, Rina Ota, Chihiro Tsukano, Yoshiji Takemoto
The 26th ISHC Congress      Sep 2017   [Refereed]
Direct and divergent N-glycofunctionalization of amides utilizing halogenated azolium salts
Yusuke Kobayashi, 〇Yuya Nakatsuji, S. Li, Yoshiji Takemoto
The 26th ISHC Congress      Sep 2017   [Refereed]
First Total Synthesis of Avenaol: New Strategy for Synthesis of All-cis Substituted Cyclopropane Natural Products
〇Motohiro Yasui, Rina Ota, Chihiro Tsukano, and Yoshiji Takemoto
The 10th Seoul-Kyoto-Osaka Joint Symposium On Pharmaceutical Sciences For Young Scientists      May 2017
Total Synthesis of Caprazamycin A and CPZEN-45
〇Chihiro Tsukano, Hugh Nakamura, Takuma Yoshida, and Yoshiji Takemoto
ACP-2016-Korea      Oct 2016   [Refereed][Invited]
Takuma Yoshida, Hugh Nakamura, Chihiro Tsukano, and 〇Yoshiji Takemoto
ISHCXX      Jul 2016   [Refereed]
〇Chihiro Tsukano, Satoshi Suetsugu, Nubusuke Muto, Misa Horinouchi, and Yoshiji Takemoto
ISHCXX      Jul 2016   [Refereed]
Catalytic asymmetric synthesis of anti-α,β-diamino acid derivatives toward peptide ligation
〇Sanae Izumi, Yusuke Kobayashi, Yoshiji Takemoto
The 8th Takeda Science Foundation Symposium on PharmaSciences      Jan 2016   [Refereed]
Catalytic asymmetric synthesis of anti-α,β-diamino acid derivatives
〇Sanae Izumi, Yusuke Kobayashi, Yoshiji Takemoto
Pacifichem 2015      Dec 2015   [Refereed]
Direct dehydroxylative coupling reaction of alcohol with organosilanes through Si-X bond activation by halogen bonding
○Masato Saito, Nobuya Tsuji, Yusuke Kobayashi, Yoshiji Takemoto
The 13th International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-13)      Nov 2015   [Refereed]
〇Hugh Nakamura, Chihiro Tsukano, Motohiro Yasui, Yoshiji Takemoto
The 9th Seoul-Kyoto-Osaka Joint Symposium      Nov 2015
〇Hugh Nakamura, Chihiro Tsukano, Motohiro Yasui, Yoshiji Takemoto
The 25th ISHC Congress      Aug 2015   [Refereed]
Palladium-Catalyzed Amidation by Chemoselective C(sp3)-H functionalization: Concise Route to Oxindoles and its application
〇Chihiro Tsukano, Masataka, Okuno, Takeshi Nanjo, Nobusuke Muto, Yoshiji Takemoto
The 25th ISHC Congress      Aug 2015   [Refereed]
he use of halogen bond (XB) donors as organo-Lewis acids in co-catalyst systems to mediate unique synthetic transformations
〇Yusuke Kobayashi, Masato Saito, Shanji Li, and Yoshiji Takemoto
The 39th Naito Conference      Jul 2015   [Refereed]
〇Hugh Nakamura, Chihiro Tsukano, Motohiro Yasui, Yoshiji Takemoto
The 39th Naito Conference      Jul 2015   [Refereed]
Chihiro Tsukano, Nobusuke Muto, Iderbat Enkhtaivan, Yoshiji Takemoto
The 2nd International Conference on Organometallics and Catalysis      Oct 2014   [Refereed]
Chihiro Tsukano, Masataka Okuno, Hiromi Nishiguchi, Yoshiji Takemoto
ICOMC2014      Jul 2014   [Refereed]
Synthesis of Indole Derivatives by Palladium-Catalyzed Isocyanide Insertion
Takeshi Nanjo, Sho Yamamoto, Chihiro Tsukano, Yoshiji Takemoto
ICOMC2014      Jul 2014   [Refereed]
Palladium-catalyzed indole synthesis using isocyanide insertion
Takeshi Nanjo, Chihiro Tsukano, Yoshiji Takemoto
ISHHC-16      Aug 2013   [Refereed]
Direct Thioesterification of Aldehydes via Oxidative NHC-Catalysis: Expansion into Dynamic Kinetic Resolution
Takuya Uno, Yusuke Kobayashi, Yoshiji Takemoto
First Japan-USA Organocatalytic Symposium      Dec 2012   [Refereed]
An Efficient Synthesis of Quinoxalinone-Containing Pharmaceuticals via Aerobic Oxidative C–N Bond Formation
Yusuke Kobayashi, Tetsutaro Kimachi, Yoshiji Takemoto
IKCOC-12      Nov 2012   [Refereed]
Takuya Uno, Yoshiji Takemoto
IKCOC-12      Nov 2012   [Refereed]
An Efficient Synthesis of Quinoxalinone-containing Pharmaceuticals via Aerobic Oxidative C-N Bond Formation
Yusuke Kobayashi, Tetsutaro Kimachi, Yoshiji Takemoto
The 6th Takeda Science Foundation Symposium on Pharmasciences      Sep 2012   [Refereed]
Oxindole Synthesis via Palladium-Catalyzed Chemoselective C(sp3)–H activation
Chihiro Tsukano, Masataka Okuno, Yoshiji Takemoto
The 6th Takeda Science Foundation Symposium on Pharmasciences      Sep 2012   [Refereed]
Takuya Uno, Yoshiji Takemoto
The 6th Takeda Science Foundation Symposium on Pharmasciences      Sep 2012   [Refereed]
Development of Tricyclic Cyclobutanols as a pH-dependent DNA Alkylating Agent
Yuuki Nagamoto, Akira Hattori, Yoshiji Takemoto, Kiyosei Takasu
The 19th International Conference on Organic Synthesis      Jul 2012   [Refereed]
Development of Tricyclic Cyclobutanols as a pH-dependent DNA Alkylating Agent
Yuuki Nagamoto, Akira Hattori, Kiyosei Takasu, Yoshiji Takemoto
7th Seoul-Kyoto-Osaka Joint Symposium      May 2012   [Refereed]
Synthesis of Aminourea-Substrate Complex Models and Mechanistic Study
Takumi Azuma, Yusuke Kobayashi, Yoshiji Takemoto
First Japan-USA Organocatalytic Symposium      2012   [Refereed]
Synthesis of Highly Oxidized Quinolizidine by Reductive Cyclization via Acylpyridinium Cation, and Its Application
Chihiro Tsukano, Atsuko Oimura, Yoshiji Takemoto
8th AFMC International Medicinal Chemistry Symposium      Nov 2011   [Refereed]
Development of pH-triggered DNA alkylating agents based on ring contraction reaction
Yuuki Nagamoto, Yoshiji Takemoto, Kiyosei Takasu
8th AFMC International Medicinal Chemistry Symposium      Nov 2011   [Refereed]
Synthetic Studies on Caprazamycin A
Shota Sakamoto, Shinsuke Yokouchi, Chihiro Tsukano, Yoshiji Takemoto
8th AFMC International Medicinal Chemistry Symposium      Nov 2011   [Refereed]
Synthetic Studies on Perophoramidine; Quaternary Carbon Construction via Intramolecular SmI_2-Mediated Reductive Cyclization
Takayuki Ishida, Chihiro Tsukano, Yoshiji Takemoto
8th AFMC International Medicinal Chemistry Symposium      Nov 2011   [Refereed]
Formal (3 + 3) Cycloaddition of Silyl Enol Ethers Catalyzed by Trifric Imide: Domino Michael Addition―Claisen Condensation
Takumi Azuma, Yoshiji Takemoto, Kiyosei Takasu
8th AFMC International Medicinal Chemistry Symposium      Nov 2011   [Refereed]
Studies towards the Organocatalytic, Asymmetric Total Synthesis of Nakadomarin A
Michael Stadler, Nobuya Tsuji, Tsubasa Inokuma, Yoshiji Takemoto
First Germany-Japan Organocatalytic Symposium      Oct 2011   [Refereed]
N-Heterocyclic Carbene-Catalyzed Oxidative Thioesterification of Aldehydes
Takuya Uno, Yoshiji Takemoto
First Germany-Japan Organocatalytic Symposium      Oct 2011   [Refereed]
Tf2NH- Catalyzed Domino Reaction of Ynamides with Imines: Synthesis of α,β-Unsaturated Amidines and Quinolines
Kiyosei Takasu, Yusuke Kuroda, Naoya Shindoh, Yoshiji Takemoto
First Germany-Japan Organocatalytic Symposium      Oct 2011   [Refereed]
Catalytic Asymmetric Synthesis of 3-membered cyclic compounds
Shota Sakamoto, Tubasa Inokuma, Yoshiji Takemoto
The 2nd International Symposium on Process Chemistry      Aug 2011   [Refereed]
2-Iminoindoline Syntheses via SmI2-Mediated Reductive Cyclization: Synthetic Studies on Perophoramidine Skeleton
Takayuki Ishida, Chihiro Tsukano, Yoshiji Takemoto
OMCOS16      Jul 2011   [Refereed]
Studies on Synthesis of 2-Iminoindoline Skeleton via Samarium Diiodide-Mediated Reductive Cyclization
Takayuki Ishida, Chihiro Tsukano, Yoshiji Takemoto
ChemComm International Symposium      May 2011   [Refereed]
Michael Stadler, Nobuya Tsuji, Tsubasa Inokuma, and Yoshiji Takemoto
ChemComm International Symposium      May 2011   [Refereed]
Stereocotrolled Synthesis of Spirocyclopropanes from Fused-cyclobutanols by Ring Contraction
Yuuki Nagamoto, Kiyosei Takasu, Yoshiji Takemoto
ChemComm International Symposium      May 2011   [Refereed]

Books etc

 
Asymmetric Dearomatization Reactions
Chihiro Tsukano, Yoshiji Takemoto (Part:Contributor, Chapter 11. Dearomatization Reactions of Electron-Deficient Aromatic Rings)
Wiley-VCH Verlag   Aug 2016   
Bifunctional Guanidines as Hydrogen-Bond Donating Catalysts
Yusuke Kobayashi, Yoshiji Takemoto (Part:Contributor, Topics in Heterocyclic Chemistry “Guanidines as Reagents and Catalysts”)
Springer   Jun 2015   
Comprehensive Organic Synthesis, 2nd edition
Miyabe, H.; Takemoto, Y. (Part:Contributor, 1.19 Carbonyl and Imine Activation)
Elsevier   May 2014   ISBN:978-0-08-097743-0
Asymmetric Synthesis: More Methods and Applications
Takemoto, Y.; Inokuma, T (Part:Contributor, Bifunctional Thiourea Catalysts. In Asymmetric Synthesis: More Methods and Applications)
Wiley-VCH   Nov 2012   ISBN:978-3-527-32900-7
Comprehensive Chirality, Volume 6
Takemoto Y.; Stadler M. (Part:Contributor, C-C Bond Formation: Michael Reaction)
Elsevier   Oct 2012   ISBN:978-0-08-095167-6
Science of Synthesis: Asymmetric Organocatalysis 2, Brønsted Base and Acid Catalysts, and Additional Topics
Inokuma, T.; Takemoto, Y. (Part:Contributor, Bifunctional (Thio)urea and BINOL Catalysts. In Science of Synthesis: Asymmetric Organocatalysis 2)
Thieme   May 2012   ISBN:9783131693716
Catalytic Asymmetric Synthesis 3rd ed.
Y. Takemoto, H. Miyabe (Part:Contributor, Asymmetric Carbon-Heteroatom Bond-Forming Reactions)
John Wiley & Sons   Feb 2010   ISBN:978-0-470-17577-4
Comprehensive Organometallic Chemistry III
Y. Takemoto, H. Miyabe (Part:Contributor, 10.15 C-N Bond Formation through Amination)
Elsevier   Dec 2006   
Stereoselective synthesis of spirovetivane-type phytoalexins(jointly worked)
竹本 佳司
"Handbook of phytoalexin metabolism and action"Marcel Dekker, inc. ,,/,445   1995   

Conference Activities & Talks

 
Design of Bifunctional Thiourea Catalysts for Asymmetric Reactions [Invited]
Yoshiji Takemoto
Lecture in the Chinese University of Hong Kong   17 May 2019   
Organocatalyzed Reactions Directed Toward Natural Product Synthesis [Invited]
Yoshiji Takemoto
Seminar in the Hong Kong University of Science and Technology   16 May 2019   
Organocatalyzed Reactions Directed Toward Natural Product Synthesis [Invited]
Yoshiji Takemoto
Seminar in the Chinese University of Hong Kong   15 May 2019   
Creation of multifunctional catalysts using hydrogen-bond donors and Lewis acids [Invited]
Yoshiji Takemoto
ACP Lectureship in Taiwan (Chung Yuan Christian University)   30 Mar 2018   
Creation of multifunctional catalysts using hydrogen-bond donors and Lewis acids [Invited]
Yoshiji Takemoto
ACP Lectureship in Taiwan (Academia Sinica)   29 Mar 2018   
Creation of multifunctional catalysts using hydrogen-bond donors and Lewis acids [Invited]
Yoshiji Takemoto
ACP Lectureship in Taiwan (National Chung Hsing University)   28 Mar 2018   
Creation of multifunctional catalysts using hydrogen-bond donors and Lewis acids [Invited]
Yoshiji Takemoto
ACP Lectureship in Taiwan (National Taiwan Normal University)   26 Mar 2018   
Mechanistic insight into asymmetric hetero-Michael addition of α,β- unsaturated carboxylic acids catalyzed by multi-functional thioureas
Yoshiji Takemoto
The 12th International Conference on Cutting-Edge Organic Chemistry in Asia ICCEOCA-12   3 Nov 2017   
Bifunctional, Dual, and Integrated Organocatalysis for Asymmetric Reactions [Invited]
TAKEMOTO Yoshiji
Sprcial Lecture in East China University of Science and Technology   6 May 2016   
Bifunctional, Dual, and Integrated Organocatalysis for Asymmetric Reactions [Invited]
TAKEMOTO Yoshiji
Sprcial Lecture in Shanghai Institute of Organic Chemistry   4 May 2016   
Bifunctional, Dual, and Integrated Organocatalysis for Asymmetric Reactions [Invited]
TAKEMOTO Yoshiji
Seminor in Shanghai Jlao Tong University   3 May 2016   
Organocatalyzed Asymmetric Reactions for Process Chemistry [Invited]
TAKEMOTO Yoshiji
Bayer-Kyoto Workshop   15 Apr 2016   
Hetero-Michael addition to α,β-unsaturated carboxylic acids [Invited]
TAKEMOTO Yoshiji
Pacifichem 2015   17 Dec 2015   
Asymmetric catalysis for the Michael addition of α,β-unsaturated carboxylic acids
TAKEMOTO Yoshiji
Chemical Research Center of Hungarian Academy of Sciences, Budapest, Hungary   31 Jul 2015   
Asymmetric catalysis for the Michael addition of α,β-unsaturated carboxylic acids
TAKEMOTO Yoshiji
University of Vienna   30 Jul 2015   
Asymmetric catalysis for the Michael addition of α,β-unsaturated carboxylic acids
TAKEMOTO Yoshiji
University of Bologna   28 Jul 2015   
Asymmetric catalysis for the Michael addition of α,β-unsaturated carboxylic acids
TAKEMOTO Yoshiji
Università degli Studi di Parma   27 Jul 2015   
Asymmetric catalysis for the Michael addition of α,β-unsaturated carboxylic acids [Invited]
TAKEMOTO Yoshiji
The chemistry of organocatalysts   8 Jul 2015   The Naito Foundation
Asymmetric hetero-Michael reaction of α,β-unsaturated carboxylic acid derivatives [Invited]
TAKEMOTO Yoshiji
The 13th Eurasia Conference in Chemical Sciences   17 Dec 2014   IIS
Asymmetric hetero-Michael reaction of α,β-unsaturated carboxylic acid derivatives [Invited]
TAKEMOTO Yoshiji
Advanced Molecular Transformations by Organocatalysts: 2nd International Conference   21 Nov 2014   
Asymmetric Reactions Using Bifunctional HB-Donor Catalysts [Invited]
TAKEMOTO Yoshiji
CNS Special Lecture   4 Nov 2014   Ewha Womans University
Asymmetric Reactions Using Bifunctional HB-Donor Catalysts [Invited]
TAKEMOTO Yoshiji
DS Special Lecture   3 Nov 2014   Sungkyunkwan University
Asymmetric Reactions Using Bifunctional Hydrogen-Bond-Donor Catalysts [Invited]
TAKEMOTO Yoshiji
Indo Japanese Conference on Process Chemistry R & D 2014   30 Jan 2014   Society of Japan Process Chemistry
Asymmetric Reactions Using Bifunctional HB-Donor Catalysts [Invited]
TAKEMOTO Yoshiji
IITB Special Lecture   29 Jan 2014   Indian Institute of Technology Bombay
Asymmetric Reactions Using Bifunctional HB-Donor Catalysts [Invited]
TAKEMOTO Yoshiji
DOC Special Lecture   28 Jan 2014   Indian Institute of Science
Asymmetric Reactions Using Bifunctional HB-Donor Catalysts [Invited]
TAKEMOTO Yoshiji
New Chemistry Unit Special Lecture   27 Jan 2014   Jawaharlal Nehru Centre for Advanced Scientific Research
Hydrogen-Bond Donor Catalysts for Process Chemistry [Invited]
TAKEMOTO Yoshiji
ECPM Special Lecture   18 Oct 2013   University of Strasbourg
ydrogen-Bond Donor Catalysts for Process Chemistry [Invited]
TAKEMOTO Yoshiji
IRCOF Special Lecture   16 Oct 2013   University of Rouen
Hydrogen-Bond Donor Catalysts for Process Chemistry [Invited]
TAKEMOTO Yoshiji
ICMT Special Lecture   11 Oct 2013   Caen University
Hydrogen-Bond Donor Catalysts for Process Chemistry [Invited]
TAKEMOTO Yoshiji
iSm2 Special Lecture   8 Oct 2013   Aix-Marseille University
Asymmetric Catalysis with HB Donor and NHC Catalysts [Invited]
Yoshiji Takemoto
Advanced Molecular Transformations by Organocatalysts: 1st International Conference   27 May 2013   Professor Masahiro Terada
Mechanistic study on the bifunctional thiourea-catalyzed reactions [Invited]
Yoshiji Takemoto
Japan-USA Organocatalytic Symposium in Hawaii   15 Dec 2012   Professor Keiji Maruoka
Asymmetric Synthesis with organocatalysts [Invited]
TAKEMOTO Yoshiji
Bristol-Kyoto Organic Synthesis Workshop in Kyoto   16 Nov 2012   Kyoto University
Asymmetric organocatalysis with bifunctional thioureas and newly designed hydrogen-bond donors [Invited]
Yoshiji Takemoto
International Conference “Catalysis in Organic Synthesis”ICCOS-2012   15 Sep 2012   Russia Academy
Asymmetric Organocatalysis: Toward Multifunctional Hydrogen-bond Donor Catalysts [Invited]
Yoshiji Takemoto
The 6th Takeda Science Foundation Symposium on PharmaSciences “How Fascinating the Synthetic Organic Chemistry is!”   13 Sep 2012   武田振興財団
Asymmetric Catalysis with Newly Designed Bifunctional Hydrogen-Bond Donors [Invited]
TAKEMOTO Yoshiji
1st Germany-Japan Organocatalytic Symposium (Kyoto, Japan)   14 Oct 2011   Professor Keiji Maruoka
Asymmetric catalysis with hydrogen-bond donors [Invited]
Yoshiji Takemoto
Pacifichem 2010   17 Dec 2010   日米化学会
Asymmetric Catalysis with New Hydrogen-bond Donors [Invited]
Yoshiji Takemoto
International Symposium on Organocatalysis   15 Jul 2010   Professor Benjamin List
Asymmetric Synthesis with Multi-Functional Thioureas [Invited]
TAKEMOTO Yoshiji
Special Lecture   31 Jul 2009   Johnson-Johnson
Asymmetric Synthesis with Multi-Functional Thioureas [Invited]
TAKEMOTO Yoshiji
Special Lecture   24 Jul 2009   Novartis Pharma AG
Asymmetric Synthesis with Multi-Functional Thioureas [Invited]
TAKEMOTO Yoshiji
Special Lecture   23 Jul 2009   Sanofi aventis
Asymmetric Synthesis with Multi-Functional Thioureas [Invited]
TAKEMOTO Yoshiji
Special Lecture   21 Jul 2009   F. Hoffmann-La Roche Ltd
Asymmetric Catalysis with Multi-Functional Thioureas [Invited]
TAKEMOTO Yoshiji
Novel Chiral Chemistries Japan(NCCJ)2009   18 Apr 2009   
Organocatalytic Asymmetric Reactions with Newly Designed Multi-functional Thiourea Catalysts [Invited]
TAKEMOTO Yoshiji
UK/Japan Symposium on Asymmetric Catalysis   9 Dec 2008   
Enantioselective Petasis-Type Reaction with Multi-Functional Thiourea [Invited]
Yoshiji Takemoto
First Japan-Singapore Bilateral Symposium on Catalysis   6 Jan 2008   Singapore National University
Asymmetric Catalysis with Multi-functional Thioureas [Invited]
Yoshiji Takemoto
Agenda 2nd Flash Conference   30 Oct 2007   
Asymmetric Catalysis with Multi-functional Thioureas [Invited]
Yoshiji Takemoto
The Fourth International Symposium on Integrated Synthesis   23 Sep 2007   Professor Jyun-ichi Yoshida
Development of Catalytic Asymmetric Reactions with Newly Designed Multi-functional Thiourea Catalysts [Invited]
Yoshiji Takemoto
International Asymmetric Organocatalytic Conference   28 May 2007   Professor Keiji Maruoka
Stereoselective catalysis with thiourea derivatives [Invited]
Yoshiji Takemoto
5th Tutzing Symposion Organocatalysis   8 Oct 2006   ドイツ化学会
Bifunctional Thiourea Catalysts for Asymmetric Nucleophilic Reactions [Invited]
TAKEMOTO Yoshiji
The 16th International Conference on Organic Synthesis   13 Jun 2006   
Asymmetric Reactions Using Bifunctional Thiourea Catalysts [Invited]
Yoshiji Takemoto
PacificChem 2005   15 Dec 2005   日米化学会
Stereoselective Reactions Using Metal-Complexes
Yoshiji Takemoto
KOREA-JAPAN YOUNG SCINTISTS JOINT SYMPOSIUM   28 Jul 2003   The Seoul National University
Stereoselective reactions using metal-complexes [Invited]
TAKEMOTO Yoshiji
special lecture   13 May 2003   Bayer Yakuhin Reseach Center Kyoto

Works

 
Development of new detector of Marin Toxins
1997
Development of new synthetic method for heterocyclic compounds
2004
Development of chiral catalysts
2005

Research Grants & Projects

 
Asymmetric Synthesis Using Organometal Complexes
Development of environmentally benign reaction
Catalytic asymmetric reaction
Development of new solid phase differenciating prochirality

Patents

 
特願平2-110223 : Preparation of (4R,5R)-4-[(S)-(1-amino-2- cyclohexyl)ethyl]-1,3-dioxolane derivatives.
特願平1-259992 : Manufacture of 4-amino-3-hydroxypentanoic acid derivatives.
Terajima, Y. Takemoto, Y. Ito & M. Matsumoto