2020年6月7日
A solvent-dependent chirality-switchable thia-Michael addition to α,β-unsaturated carboxylic acids using a chiral multifunctional thiourea catalyst
Chemical Science
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- 巻
- 11
- 号
- 21
- 開始ページ
- 5572
- 終了ページ
- 5576
- 記述言語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1039/d0sc01729a
© The Royal Society of Chemistry 2020. An asymmetric thia-Michael addition of arylthiols to α,β-unsaturated carboxylic acids using a thiourea catalyst that bears arylboronic acid and tertiary amine moieties is reported. Both enantiomers of the Michael adducts can be obtained in high enantioselectivity and good yield merely by changing the solvent. The origin of the chirality switch in the products was examined in each solventviaspectroscopic analyses.
- リンク情報
- ID情報
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- DOI : 10.1039/d0sc01729a
- ISSN : 2041-6520
- eISSN : 2041-6539
- SCOPUS ID : 85086043230