中嶋弘一 (Koichi Nakajima) - マイポータル - researchmap

基本情報

所属: 大阪市立大学大学院医学研究科基礎医科学専攻教授

学位: 医学博士(大阪大学)

J-GLOBAL ID: 200901024057430774
researchmap会員ID: 1000031733

外部リンク: http://www.med.osaka-cu.ac.jp/immune/

研究キーワード

2

研究分野

2

学歴

4

MISC

44

The YXXQ motif in gp 130 is crucial for STAT3 phosphorylation at Ser727 through an H7-sensitive kinase pathway

K Abe, M Hirai, K Mizuno, N Higashi, T Sekimoto, T Miki, T Hirano, K Nakajima

ONCOGENE 20(27) 3464-3474 2001年6月
No Involvement of Erk/MAP Kinases in IL-6-induced Proliferation of a B Cell Hybridoma Cell Line

Abe Koji, Mizuno Katsunori, 中嶋弘一

Osaka City Medical journal 47(1) 63-72 2001年
Tissue-specific autoregulation of the stat3 gene and its role in interleukin 6-induced survival signals in T cells.

Mol.Cell. Biol. 21(19) 6615-6625 2001年
Biologic significance of GATA-1 activities in Ras-mediated megakaryocytic differentiation of hematopoietic cell lines

Matsumura, I, A Kawasaki, H Tanaka, J Sonoyama, S Ezoe, N Minegishi, K Nakajima, M Yamamoto, Y Kanakura

BLOOD 96(7) 2440-2450 2000年10月
GATA-1 blocks IL-6-induced macrophage differentiation and apoptosis through the sustained expression of cyclin D1 and Bcl-2 in a murine myeloid cell line M1

H Tanaka, Matsumura, I, K Nakajima, H Daino, J Sonoyama, H Yoshida, K Oritani, T Machii, M Yamamoto, T Hirano …

BLOOD 95(4) 1264-1273 2000年2月
Characterization of IL-4 and IL-13 signals dependent on the human IL-13 receptor a chain 1:redundancy of requirement of tyrosine residue for STAT3 activation.

Intl.Immunol. 12(11) 1499-1509 2000年
Full oncogenic activities of v-Src are mediated by multiple signaling pathways. Ras as an essential mediator for cell survival.

J. Biol. Chem. 275(31) 24096-24105 2000年
Increased D-type cyclin expression together with decreased cdc2 activity confers megakaryocytic differentiation of a human thrombopoietin-dependent hematopoietic cell line.

J. Biol. Chem. 275(8) 5553-5559 2000年
Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1

M Kortylewski, PC Heinrich, A Mackiewicz, U Schniertshauer, U Klingmuller, K Nakajima, T Hirano, F Horn, Behrmann, I

ONCOGENE 18(25) 3742-3753 1999年6月
Both stat3-activation and Stat3-independent BCL2 downregulation are important for interleukin-6 induced apoptosis of 1A9-M cells

K Oritani, Y Tomiyama, PW Kincade, K Aoyama, T Yokota, Matsumura, I, Y Kanakura, K Nakajima, T Hirano, Y Matsuzawa

BLOOD 93(4) 1346-1354 1999年2月
Signal transducer and activator of transcription-1 and Heat shock factor-1 interact and activate the transcription of the Hsp-70 and Hsp-90β gene promoters.

J. Biol. chem. 274(3) 1723-1728 1999年
STAT3 is required for the gp130-mediated full activation of the c-myc gene.

J. Exp. Med. 189(1) 63-73 1999年
STAT3 orchestrates contradictory signals in cytokine-induced G(1) to S cell-cycle transition

T Fukada, T Ohtani, Y Yoshida, T Shirogane, K Nishida, K Nakajima, M Hibi, T Hirano

EMBO JOURNAL 17(22) 6670-6677 1998年11月
A novel function of Stat1 alpha and Stat3 proteins in erythropoietin-induced erythroid differentiation of a human leukemia cell line

K Kirito, M Uchida, M Takatoku, K Nakajima, T Hirano, Y Miura, N Komatsu

BLOOD 92(2) 462-471 1998年7月
Involvement of prolonged Ras activation thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell line.

Mol. Cell. Biol. 18 4282-4290 1998年
Gab1 acts an an adaptor molecule linking a cytokine receptor gp130to ERK MAP kinase.

Mol. Cell. Biol. 18 4109-4117 1998年
Autoregulation of the Stat3 gene through cooperation with a CRE site binding protein.

J. Biol. Chem. 273(11) 6132-6138 1998年
Dual control of neurite outgrowth by STAT3 and MAP kinase in PC12 cells stimulated with interleukin-6

S Ihara, K Nakajima, T Fukada, M Hibi, S Nagata, T Hirano, Y Fukui

EMBO JOURNAL 16(17) 5345-5352 1997年9月
Association of Stat3-dependent transcriptional activation of p19(INK4D) with IL-6-induced growth arrest

M Narimatsu, K Nakajima, M Ichiba, T Hirano

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 238(3) 764-768 1997年9月
Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21(WAF1/Cip1) by STAT5

Matsumura, I, J Ishikawa, K Nakajima, K Oritani, Y Tomiyama, JI Miyagawa, T Kato, H Miyazaki, Y Matsuzawa, Y Kanakura

MOLECULAR AND CELLULAR BIOLOGY 17(5) 2933-2943 1997年5月

もっとみる

書籍等出版物

1

Interleukin 6 receptor-mediated signal transduction pathways

Gann Monograph on Cancer Res. 1994年

所属学協会

5

共同研究・競争的資金等の研究課題

2