ADACHI Taiji

J-GLOBAL         Last updated: Jun 23, 2019 at 17:02
 
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Name
ADACHI Taiji
Affiliation
Kyoto University
Section
Graduate School of Engineering
Degree
Dr. Eng.(Osaka University)
ORCID ID
0000-0001-5280-4156

Research Areas

 
 

Academic & Professional Experience

 
1992
 - 
1998
Research Associate, Kobe University
 
1997
 - 
1999
Research Fellow, The University of Michigan
 
1998
 - 
1999
Postdoctoral Fellow for Research Abroad, JSPS
 
1998
 - 
2001
Associate Professor
 
1998
 - 
2001
Visiting Research Fellow, RIKEN
 

Education

 
 
 - 
1992
Division of Mechanical Engineering, Graduate School, Division of Engineering Science, Osaka University
 

Published Papers

 
Masamu Inoue, Takehito Ono, Yoshitaka Kameo, Fumiyuki Sasaki, Takashi Ono, Taiji Adachi, Tomoki Nakashima
Scientific Reports   9    Dec 2019
© 2019, The Author(s). Bone undergoes a constant reconstruction process of resorption and formation called bone remodeling, so that it can endure mechanical loading. During food ingestion, masticatory muscles generate the required masticatory forc...
Atsushi Matsuda, Jing Li, Peter Brumm, Taiji Adachi, Yasuhiro Inoue, Taeyoon Kim
Biophysical Journal   116 2161-2171   Jun 2019
© 2019 Biophysical Society Cells generate mechanical forces primarily from interactions between F-actin, cross-linking proteins, myosin motors, and other actin-binding proteins in the cytoskeleton. To understand how molecular interactions between ...
Shunsuke Kawai, Hiroyuki Yoshitomi, Junko Sunaga, Cantas Alev, Sanae Nagata, Megumi Nishio, Masataka Hada, Yuko Koyama, Maya Uemura, Kazuya Sekiguchi, Hirotsugu Maekawa, Makoto Ikeya, Sakura Tamaki, Yonghui Jin, Yuki Harada, Kenichi Fukiage, Taiji Adachi, Shuichi Matsuda, Junya Toguchida
Nature Biomedical Engineering      Jan 2019
© 2019, The Author(s), under exclusive licence to Springer Nature Limited. The recapitulation of bone formation via the in vitro generation of bone-like nodules is frequently used to understand bone development. However, current bone-induction tec...
S. Okuda, N. Takata, Y. Hasegawa, M. Kawada, Y. Inoue, T. Adachi, Y. Sasai, M. Eiraku
Science Advances   4    Nov 2018
Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. Organogenesis is a self-organizing process of multiple cells in three-dimensional (3D) space, where macroscopic tissue defo...
Stefania Marcotti, Koichiro Maki, Gwendolen C. Reilly, Damien Lacroix, Taiji Adachi
PLoS ONE   13    Oct 2018
© 2018 Marcotti et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ar...
Satoru Okuda, Takashi Miura, Yasuhiro Inoue, Taiji Adachi, Mototsugu Eiraku
SCIENTIFIC REPORTS   8(1)    Jun 2018   [Refereed]
Tomoyasu Shinoda, Arata Nagasaka, Yasuhiro Inoue, Ryo Higuchi, Yoshiaki Minami, Kagayaki Kato, Makoto Suzuki, Takefumi Kondo, Takumi Kawaue, Kanako Saito, Naoto Ueno, Yugo Fukazawa, Masaharu Nagayama, Takashi Miura, Taiji Adachi, Takaki Miyata
PLoS Biology   16    Apr 2018
© 2018 Shinoda et al. Neural progenitor cells (NPCs), which are apicobasally elongated and densely packed in the developing brain, systematically move their nuclei/somata in a cell cycle–dependent manner, called interkinetic nuclear migration (IKN...
Tomoyasu Shinoda, Arata Nagasaka, Yasuhiro Inoue, Ryo Higuchi, Yoshiaki Minami, Kagayaki Kato, Makoto Suzuki, Takefumi Kondo, Takumi Kawaue, Kanako Saito, Naoto Ueno, Yugo Fukazawa, Masaharu Nagayama, Takashi Miura, Taiji Adachi, Takaki Miyata
PLOS BIOLOGY   16(4)    Apr 2018   [Refereed]
Satoru Okuda, Takashi Miura, Yasuhiro Inoue, Taiji Adachi, Mototsugu Eiraku
SCIENTIFIC REPORTS   8(1)    Feb 2018   [Refereed]
Taiji Adachi, Yoshitaka Kameo
CISM International Centre for Mechanical Sciences, Courses and Lectures   578 231-257   Jan 2018
© 2018, CISM International Centre for Mechanical Sciences. In bone remodeling, a variety of mechanical and biochemical signaling occurs among osteoclasts and osteoblasts, which are responsible for bone resorption and formation, and osteocytes, whi...

Misc

 
Sung Woong Han, Sung Woong Han, Kyohei Morita, Kyohei Morita, Taiji Adachi, Taiji Adachi
Science of Advanced Materials   6 2453-2458   Jan 2014
© 2014 by American Scientific Publishers. Actin filament senses mechanical forces and it is transduced into biochemical signals during many cellular processes. In bending of actin filaments, actin-related protein 2/3 (Arp2/3) complex plays a centr...
Yoshitaka Kameo, Taiji Adachi
Acta Mechanica   225 2833-2840   Jan 2014
© 2014, Springer-Verlag Wien. Cancellous bone has a complicated three-dimensional porous microstructure that consists of strut-like or plate-like trabeculae. The arrangement of the trabeculae is remodeled throughout the organism’s lifetime to func...
Taiji Adachi, Naoki Kida
Journal of Biomechanical Science and Engineering   9    Jan 2014
In this study, for a better understanding of arterial functions, we examine the effects of active stresses, which are generated by contractile units included in smooth muscle cells, on the stress distribution in the arterial wall. Thus far, it is ...
Sung Woong Han, Sung Woong Han, Kyohei Morita, Patriche Simona, Patriche Simona, Takanori Kihara, Jun Miyake, Mihaela Banu, Taiji Adachi, Taiji Adachi
Journal of Nanoscience and Nanotechnology   14 5654-5657   Jan 2014
Actin filaments play essential roles in many kinds of cellular functions by interacting with hundreds of actin binding proteins. Here we probe the interaction between actin filament and a binding protein, α-actinin, using an atomic force microscop...
Hiromi Miyoshi, Taiji Adachi
Tissue Engineering - Part B: Reviews   20 609-627   Jan 2014
© 2014, Mary Ann Liebert, Inc. The physiological role of the actin cytoskeleton is well known: it provides mechanical support and endogenous force generation for formation of a cell shape and for migration. Furthermore, a growing number of studies...
Satoru Hayano, Hiroshi Kurosaka, Takeshi Yanagita, Ina Kalus, Fabian Milz, Yoshihito Ishihara, Md Nurul Islam, Noriaki Kawanabe, Masahiro Saito, Hiroshi Kamioka, Taiji Adachi, Thomas Dierks, Takashi Yamashiro
Journal of Biological Chemistry   287 12217-12229   Apr 2012
Cell surface heparan sulfate (HS) is an essential regulator of cell signaling and development. HS traps signaling molecules, like Wnt in the glycosaminoglycan side chains of HS proteoglycans (HSPGs), and regulates their functions. Endosulfatases S...
Mototsugu Eiraku, Mototsugu Eiraku, Taiji Adachi, Taiji Adachi, Yoshiki Sasai, Yoshiki Sasai
BioEssays   34 17-25   Jan 2012
The generation of complex organ structures such as the eye requires the intricate orchestration of multiple cellular interactions. In this paper, early retinal development is discussed with respect to the structure formation of the optic cup. Alth...
Rearrangement Dynamics of Contractile Actomyosin Network.
Yasuhiro Inoue and Taiji Adachi
10th World Congress on Computational Mechanics(WCCM2012)(2012.7.8-13.Sao Paulo, Brazil)      2012   [Refereed]
Mechanical Regulation of Actin Network Dynamnics in Migrating Cells(From Cells to Molecules).
Taiji Adachi
E-JUST Seminar(2012.5.17.Alexandria, Egypt)(Seminar)      2012   [Refereed]
Multiscale Biomechanics of Bone Functional Adaptation by Remodeling.
Taiji Adachi
Lecture at the Egypt-Japan University of Science and Technology(. 2012.5.14.Alexandria, Egypt()Lecture)      2012   [Refereed]
Image-based \nAnalysis of Spatial Organization of the Cellular Actin Cytoskeleton in Micro-topographical Environments
Hiromi Miyoshi, Jungmyoung Ju, Sang Min Lee, Jong Soo Ko, Taiji Adachi, Yutaka Yamagata
Exciting Biologies : Forces in Biology(2012.10.4-6.Dublin, Ireland)      2012   [Refereed]
Application of a Level-set Method for Simulation \nof Orthodontic Tooth Movement Using CT Image-based Voxel FE Models.
Taiji Adachi, Masakazu Hasegawa, Teruko Takano-Yamamoto
10th World Congress on Computational Mechanics(WCCM2012)(2012.7.8-13.Sao Paulo, Brazil)      2012   [Refereed]
Large Deformation of Multicellular \nTissue during Morphogenesis Using Reversible Network Reconnection Model
Satoru Okuda, Yasuhiro Inoue, Mototsugu Eiraku, Yoshiki Sasai, and Taiji Adachi
Exciting Biologies : Forces in Biology(2012.10.4-6.Dublin, Ireland)      2012   [Refereed]
Masaki Hojo, Mitsuhiro Nakamura, Mototsugu Tanaka, Taiji Adachi, Michinaka Sugano, Shojiro Ochiai, Kozo Osamura
Superconductor Science and Technology   18    Dec 2005
The mesoscopic stress and strain states of Bi2223/Ag/Ag-alloy superconducting composite tapes have been studied both analytically and experimentally under bending deformation. The tapes used in the present study were supplied as the standard sampl...
K. Sato; T. Adachi; M. Hojo; Y. Tomita
Proceedings of the 2005 Summer Bioengineering Conference   2005 217-218   Dec 2005
Taiji Adachi, Yoshitaka Shimada, Yasuhiro Inoue, Masaki Hojo
Nihon Kikai Gakkai Ronbunshu, A Hen/Transactions of the Japan Society of Mechanical Engineers, Part A   76 111-119   Aug 2010
Actin filament, the most abundant component of the cytoskeleton, plays important roles in fundamental cellular activities by dynamically changing its structure by elongation, branching, and bundling. These dynamic structural changes are regulated ...
Contributions \nof Actin Cytoskeleton and Cell-substrate Adhesion in Control of Cell Motile Behavior in Microtopographical \nEnvironments.
Hiromi Miyoshi, Taiji Adachi, Jungmyoung Ju, Sang Min Lee, Dong Jin Cho, Jong Soo Ko, Yutaka Yamagata
Joint Meeting of JSDB 45th & JSCB 64t(h 2012.5.28-31.Kobe)      2012   [Refereed]
Mathematical Model for Large Deformations \nof Multiple-cell Aggregate during Tissue Morphogenesis
Satoru Okuda, Yasuhiro Inoue, Mototsugu Eiraku, Yoshiki Sasai, Taiji Adachi
10th World Congress on Computational Mechanics(WCCM2012)(2012.7.8-13.Sao Paulo, Brazil)      2012   [Refereed]
Scott J. Hollister, Chia Ying Lin, Heesuk Kang, Taiji Adachi
Virtual Prototyping and Bio Manufacturing in Medical Applications   113-127   Dec 2008
The primary goals of tissue engineering scaffolds are to: o Provide guidance for anatomical tissue shape/volume o Provide temporary function within the tissue defect o Enhance tissue regeneration through mass transport and biologic delivery To ach...
M. Hojo; K. Nakashima; T. Kusaka; M. Tanaka; T. Adachi; T. Fukuoka; M. Ishibashi
17th European Conference on Fracture 2008: Multilevel Approach to Fracture of Materials, Components and Structures   3 2167-2174   Dec 2008
Zanchor is a novel through-thickness reinforcement technique where in-plane yarns are entangled each other by sticking with a special needle. Modes I and II interlaminar fracture toughness was investigated for carbon fiber (CF)/epoxy cross ply lam...
Mototsugu Tanaka, Hidekazu Tanaka, Masaki Hojo, Taiji Adachi, Suong Hyu Hyon, Masakazu Konda
8th World Biomaterials Congress 2008   2 805   Dec 2008
M. Hojo; M. Mizuno; T. Hobbiebrunken; M. Tanaka; T. Adachi; S.K. Ha
Advanced Composites for Efficiency and Environment - The US-Japan Conference on Composite Materials 2008, US-Japan 2008      Dec 2008
Masaki Hojo, Yukinobu Matsushita, Mototsugu Tanaka, Taiji Adachi
7th Asian-Australasian Conference on Composite Materials 2010, ACCM 2010   1 27-30   Jan 2010
Interfacial fracture behavior for GF/epoxy model composites was investigated under static and fatigue loadings using the bifiber shear (BFS) and the bifiber open (BFO) methods. Two E-glass fiber filaments (diameter: 23 or 40 μm) were bonded with b...
Remodeling Simulation Estimates Changes in Mechanical Properties \nof Osteoporotic Bone.
Daisuke Tawara, Ken Nagura, Taiji Adachi
18th Congress of the European Society of Biomechanics(ESB2012)(2012.7.1-4.Lisbon, Portugal)      2012   [Refereed]
Upregulation of Actomyosin Contractility Enhances Mechanical Integrity of Actin \nCytoskeleton in Lamellipodia
Taiji Adachi, Kennedy O. Okeyo
18th Congress of the European Society of Biomechanics(ESB2012)(2012.7.1 -4.Lisbon, Portugal)      2012   [Refereed]
Poroelastic Analysis of Interstitial Fluid Flow in Trabecula under Cyclic Loading.
Yoshitaka Kameo, Taiji Adachi
18th Congress of the European Society of Biomechanics(ESB2012)(2012.7.1-4 Lisbon, Portugal)      2012   [Refereed]
Y. Aonuma; T. Adachi; M. Tanaka; M. Hojo; T. Takano-Yamamoto; H. Kamioka
IFMBE Proceedings   23 2000-2004   Dec 2009
It is proposed that osteocytes embedded in mineralized bone matrix play a role in mechanosensory system during bone remodeling for mechanical adaptation. Various experimental and computer simulation approaches have revealed that the osteocytes sen...
Modeling and Simulation of Myosindependent \nRearrangement and Force Generation in an Actomyosin Network
Yasuhiro Inoue, Shunsuke Tsuda, Koji Nakagawa, Masaki Hojo, Taiji Adachi
Biophysical Society 56th Annual Meeting(2012.2.25-29.San Diego, U.S.A.)      2012   [Refereed]
M. Tanaka; H. Tanaka; M. Hojo; T. Adachi; M. Sugihara; M. Kotera; T. Nishino
ICCM International Conferences on Composite Materials      Dec 2009
The interface-control for HAp/PLLA composite was tried in order to improve the bonding strength. The effects of interface control on deformation and fracture properties of HAp/PLLA composites were evaluated using three-point bending tests. The eff...
Molecular Dynamics Analysis of Coupling Behaviors between Extension \nand Torsion of Actin Filaments Micro-Structured Surfaces
Shinji Matsushita, Yasuhiro Inoue, Taiji Adachi
Biophysical Society 56th Annual Meeting (2012.2.25-29.San Diego, U.S.A.)      2012   [Refereed]
M. Hojo; Y. Yoshida; M. Sugano; T. Adachi; Y. Inoue; K. Shikimachi; N. Hirano; S. Nagaya
ICCM International Conferences on Composite Materials      Dec 2009
We carried out fatigue tests of YBCO high-temperature superconducting coated conductor with Hastelloy substrate and additional Cu layer in LN 2, together with the measurement of the critical current. The addition of a Cu layer increased the fatigu...
Role \nof Actin Cytoskeletal Structure and Cell-Substrate Adhesion for Cell Migration on Micro-Structured Surfaces.
Hiromi Miyoshi, Jungmyoung Ju, Sang Min Lee, Dong Jin Cho, Jong Soo Ko, Taiji Adachi, Yutaka Yamagata
Biophysical Society 56th Annual Meeting(2012.2.25-29.San Diego, U.S.A.)      2012   [Refereed]
Shukei Sugita, Taiji Adachi, Yosuke Ueki, Masaaki Sato
Biophysical Journal   101 53-60   Jul 2011
The distribution of contractile forces generated in cytoskeletal stress fibers (SFs) contributes to cellular dynamic functions such as migration and mechanotransduction. Here we describe a novel (to our knowledge) method for measuring local tensio...
Mototsugu Eiraku, Nozomu Takata, Hiroki Ishibashi, Masako Kawada, Eriko Sakakura, Satoru Okuda, Kiyotoshi Sekiguchi, Taiji Adachi, Yoshiki Sasai
Nature   472 51-58   Apr 2011
Balanced organogenesis requires the orchestration of multiple cellular interactions to create the collective cell behaviours that progressively shape developing tissues. It is currently unclear how individual, localized parts are able to coordinat...
Microscale Fluid-flow Analysis in Osteocyte Canaliculi Using High-resolution \nImage-based Models.
Hiroshi Kamioka, Yoshitaka Kameo, Yuichi Imai, Astrid D. Bakker, Rommel G Bacabac, Takashi Yamashiro, Taiji Adachi, Jenneke Klein-Nulend
American Society of Bone and Mineral Research(2011.9.16-21 San Diego, USA).      2011   [Refereed]
Estimation of Changes in Mechanical Properties of Trabecular \nBone by Remodeling.
Daisuke Tawara, Takeshi Horikawa, Taiji Adachi
2011 World Congress on Advances in Structural Engineering and Mechanics(ASEM 11)(2011.9.18-23 Seoul, Korea).      2011   [Refereed]
A Hypothesis of Structural Optimality in Bone: Modeling \nOsteocyte Network as a Mechanosensory System
Taiji Adachi, Yoshitaka Kameo, Ken-ichi Tsubota
11th US National Congress on Computational Mechanics (USNCCM-11)(2011.7.25-29 Minneapolis, USA)      2011   [Refereed]
Shinji Matsushita, Taiji Adachi, Yasuhiro Inoue, Masaki Hojo, Masahiro Sokabe
Journal of Biomechanics   43 3162-3167   Dec 2010
It is essential to investigate the mechanical behaviour of cytoskeletal actin filaments in order to understand their critical role as mechanical components in various cellular functional activities. These actin filaments consisting of monomeric mo...
Hiroshi Kamioka, Taiji Adachi
Clinical Reviews in Bone and Mineral Metabolism   8 170-178   Dec 2010
In a variety of scientific fields, it is helpful to visualize natural phenomena. Newly developed methods of visualization often lead to breakthroughs in scientific fields. Especially, in the bioscience field, it is significant to reveal temporal-s...
M. Hojo, K. Osawa, T. Adachi, Y. Inoue, K. Osamura, S. Ochiai, N. Ayai, K. Hayashi
Physica C: Superconductivity and its Applications   470 1373-1376   Nov 2010
Tensile strain tolerance of the critical current in (Bi,Pb) 2 Sr 2 Ca 2 Cu 3 O x (Bi2223) composite superconductor is dramatically improved when the tape is laminated with stainless steel. For practical applications, it is important to understand ...
Yasuhiro Inoue, Takeji Deji, Yoshitaka Shimada, Masaki Hojo, Taiji Adachi
Computers in Biology and Medicine   40 876-882   Nov 2010
A mechanochemical relationship between intracellular flow fields of actin and remodeling of actin filaments is important to the realization of cell motility. In this study, to investigate this mechanochemical relationship, we present a mathematica...
Geometrical settings of directed medium by vector bundle description and its \napplication to biomechanics.
Hidetaka Yamaoka, Taiji Adachi
47th Annual Technical Meeting of Society of Engineering Science(2010.10.04-06 Ames, USA)      Oct 2010   [Refereed]
Kennedy Omondi Okeyo, Taiji Adachi, Masaki Hojo
Journal of Biomechanical Science and Engineering   5 186-207   Aug 2010
Cell migration is fundamental to various physiological processes, including metastasis, wound healing and tissue development. The complex processes involved in cell migration; polymerization, adhesion, and retraction, are mediated by highly orches...
Taiji Adachi, Yoshitaka Kameo, Masaki Hojo
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences   368 2669-2682   Jun 2010
In bone functional adaptation by remodelling, osteocytes in the lacuno-canalicular system are believed to play important roles in the mechanosensory system. Under dynamic loading, bone matrix deformation generates an interstitial.uid.ow in the lac...
Naoyoshi D. Kachi, Akihisa Otaka, Seungwoo Sim, Yoshihiko Kuwana, Yasushi Tamada, Junko Sunaga, Taiji Adachi, Naohide Tomita
Bio-Medical Materials and Engineering   20 55-63   May 2010
Condensation/aggregation process of rabbit-derived chondrocytes on a fibroin-coated patterned substrate was observed to estimate initial aggregation process in fibroin sponge. Chondrocytes were seeded on array of 160 μm diameter pits in three dens...
Yoshitaka Kameo, Taiji Adachi, Narumichi Sato, Masaki Hojo
Journal of the Mechanical Behavior of Biomedical Materials   3 240-248   Apr 2010
Load-induced interstitial fluid flow in lacuno-canalicular porosity is believed to play an important role in cellular activities regulating adaptive bone remodeling. To investigate interstitial fluid behavior based on poroelasticity, it is importa...
M. Hojo, M. Mizuno, T. Hobbiebrunken, T. Adachi, M. Tanaka, S. K. Ha
Plastics, Rubber and Composites   39 99-106   Mar 2010
A detailed numerical investigation has been carried out to investigate the effect of local fibre array irregularities on microscopic interfacial normal stress for transversely loaded unidirectional carbon fibre/epoxy composites with random fibre a...
Yoshitaka Shimada, Taiji Adachi, Yasuhiro Inoue, Masaki Hojo
MCB Molecular and Cellular Biomechanics   6 161-173   Aug 2009
The actin filament, which is the most abundant component of the cytoskeleton, plays important roles in fundamental cellular activities such as shape determination, cell motility, and mechanosensing. In each activity, the actin filament dynamically...
Y. Kameo, T. Adachi, M. Hojo
Poromechanics IV - 4th Biot Conference on Poromechanics   77-82   Jan 2009
We present an analytical solution of interstitial fluid pressure in poroelastic materials subjected to cyclic axial and bending loading. The analytical solution contains transient and steady-state responses. Both of them depend on three dimensionl...
Masaki Hojo, Yukinobu Matsushita, Mototsugu Tanaka, Taiji Adachi
Composites Science and Technology   68 2678-2689   Oct 2008
Interfacial fracture behavior for GF/epoxy model composites was investigated under static loading using the bifiber shear (BFS) and the bifiber open (BFO) methods. Two E-glass fiber filaments were bonded with bisphenol A type epoxy. The specimens ...
Chiaki Hiwa, Kumiko Yokota, Yoshikazu Nakai, Nobuo Tanaka, Toshiyuki Imoto, Taiji Adachi, Masaki Hojo, Shunsuke Baba
Zairyo/Journal of the Society of Materials Science, Japan   57 868-874   Sep 2008
In the aim of tissue regeneration of an alveolar bone, we developed three-dimensional fabric structural composite scaffolds using a bioabsorbable polymer. This scaffold consists of a polylactic acid (PLLA) resin fiber and a 75/25 poly L-lactide-co...
Yoshitaka Kameo, Taiji Adachi, Masaki Hojo
Journal of the Mechanics and Physics of Solids   56 1794-1805   May 2008
Poroelasticity is a theory that quantifies the time-dependent mechanical behavior of a fluid-saturated porous medium induced by the interaction between matrix deformation and interstitial fluid flow. Based on this theory, we present an analytical ...
Taiji Adachi, Katsuya Sato, Norio Higashi, Yoshihiro Tomita, Masaki Hojo
Journal of the Mechanical Behavior of Biomedical Materials   1 43-50   Jan 2008
Biochemical signals related to a mechanosensory mechanism by which cells sense mechanical stimuli have been gradually clarified by biological approaches such as blocking specific signaling pathways; however, mechanical signals such as deformation/...
Sayaka Miyabe, Takayoshi Nakano, Takuya Ishimoto, Naoki Takano, Taiji Adachi, Hiroyoshi Iwaki, Akio Kobayashi, Kunio Takaoka, Yukichi Umakoshi
Nippon Kinzoku Gakkaishi/Journal of the Japan Institute of Metals   72 57-62   Jan 2008
Two-dimensional quantitative analysis of microbeam X-ray diffraction (XRD) was performed using a transmission optical system to examine biological apatite (BAp) orientation in an isolated trabecula of a human fourth lumber vertebral body. The inci...
Taiji Adachi
Clinical calcium   18 342-346   Jan 2008
Osteocytes embedded in bone matrix, making a three-dimensional network system connected each other via cell processes, are considered as the mechanosensor cells that play important roles in the regulatory mechanism of adaptive bone remodeling. Thr...
M. Hojo, M. Nakamura, M. Tanaka, T. Adachi, M. Sugano, S. Ochiai, K. Osamura
Materials Science Forum   539-543 919-924   Dec 2007
The strain dependence of the critical current, Ic, of Bi2223/Ag/Ag-alloy composite superconducting tapes has been studied both experimentally and analytically under bending deformation for two types of tape used in the VAMAS bending round-robin pr...
M. Hojo, M. Hashimoto, M. Tanaka, T. Adachi, M. Sugano, S. Ochiai, K. Osamura
Physica C: Superconductivity and its Applications   463-465 863-866   Oct 2007
Young's modulus and fracture strain of Bi2223 filaments in Bi2223/Ag/Ag alloy composite tape were investigated in detail. Tensile tests were carried out for composite tapes from which Ag alloy component was completely removed by immersing the tape...
Katsuya Sato, Taiji Adachi, Daisuke Ueda, Masaki Hojo, Yoshihiro Tomita
Journal of Biomechanics   40 1246-1255   Mar 2007
In adaptive bone remodeling, it is believed that bone cells such as osteoblasts, osteocytes and osteoclasts can sense mechanical stimuli and modulate their remodeling activities. However, the mechanosensing mechanism by which these cells sense mec...
Sayaka Miyabe, Takayoshi Nakano, Takuya Ishimoto, Naoki Takano, Taiji Adachi, Hiroyoshi Iwaki, Akio Kobayashi, Kunio Takaoka, Yukichi Umakoshi
Materials Transactions   48 343-347   Mar 2007
Two-dimensional quantitative analysis of microbeam X-ray diffraction (XRD) was performed using a transmission optical system to examine biological apatite (BAp) orientation in an isolated trabecula of a human fourth lumber vertebral body. The inci...
T. Adachi, K. Sato, M. Hojo, Y. Tomita
Biomechanics at Micro- and Nanoscale Levels   49-59   Jan 2007
© 2007 by World Scientific Publishing Co. Pte. Ltd. All rights reserved. In bone functional adaptation by remodeling, it is recognized that bone cells can sense mechanical stimuli and modulate their activities. However, the mechanosensory mechanis...
Thomas Hobbiebrunken, Masaki Hojo, Taiji Adachi, Claas De Jong, Bodo Fiedler
Composites Part A: Applied Science and Manufacturing   37 2248-2256   Dec 2006
A combined experimental and numerical study has been carried out in order to study the mechanism of initial failure in transversely loaded CF/epoxy composites. Two composites with a high and a low temperature-curing matrix were investigated. Three...
Taiji Adachi, Yuki Osako, Mototsugu Tanaka, Masaki Hojo, Scott J. Hollister
Biomaterials   27 3964-3972   Jul 2006
In bone tissue engineering using a biodegradable scaffold, geometry of the porous scaffold microstructure is a key factor for controlling mechanical function of the bone-scaffold system in the regeneration process as well as after the regeneration...
Masaki Hojo, Tadashi Ando, Mototsugu Tanaka, Taiji Adachi, Shojiro Ochiai, Yoshihiro Endo
International Journal of Fatigue   28 1154-1165   Jan 2006
Interlaminar fracture toughness and delamination fatigue crack growth behavior were investigated for carbon fiber (CF)/epoxy laminates with the self-same epoxy interleaf. The matrix epoxy with a thickness of 50 μm was chosen as the interleaf mater...
T. Adachi, K. Sato
Biomechanics at Micro- and Nanoscale Levels   2 51-61   Jan 2006
© 2006 by World Scientific Publishing Co. Pte. Ltd. All rights reserved. In reorganization process of the actin stress fibers, a change in its mechanical condition has been suggested as one of the key mediators. Some experimental studies have clar...
M. Sato, Y. Takahashi, A. Yoshida, T. Adachi
Journal of Physics D: Applied Physics   41    Dec 2008
In order to study the temporal and regional variation of lightning occurrences and their relation to sprite activity and climate variability, we have analysed the 1-100 Hz ELF magnetic field waveform data obtained at the Syowa station in Antarctic...
Modelling osteocyte signalling in bone tissue adaptation.
Taiji Adachi, Yoshitaka, Kameo, Masaki Hojo
World Congress on Biomechanics(WCB2010)(2010.8.1-6 Singapore)(Invited Talk)      2010   [Refereed]
Multiscale simulation of trabecular bone adaptation by remodeling \ntoward understanding Wolff’s law.
Taiji Adachi, Yoshitaka Kameo, Masaki Hojo
The 9th World Congress on Computational Mechanics and 4th Asian Pacific Congress on Computational Mechanics(WCCM/APCOM2010)(2010.7.19-23 Sydney, Australia)(Keynote Talk)      2010   [Refereed]
Trabecular \nsurface remodeling simulation in human proximal femur using large-scale voxel FE models: Approach to \nunderstanding Wolff’s law.
Ken-ichi Tsubota, Yusuke Suzuki, Tomonori Yamada, Masaki Hojo, Akitake Makinouchi, Taiji Adachi
World Congress on Biomechanics(WCB2010)(2010.8.1-6 Singapore)      2010   [Refereed]
Control \nof cell migration on-chip by micron-sized deep and narrow grooves in a square pattern.
Hiromi Miyoshi, Jungmyoung Ju, Sang Min Lee, Dong Jin Cho, Jong Soo Ko, Taiji Adachi, Yutaka Yamagata
20th Anniversary World Congress on Biosensors(Biosensors 2010)(2010.5.26-28 Glasgow, UK)      2010   [Refereed]
Direct measurement of tension generated in cytoskeleton.
Shukei Sugita, Taiji Adachi, Yosuke Ueki, Masaaki Sato
World Congress on Biomechanics(WCB2010)(2010.8.1-6 Singapore)      2010   [Refereed]
Repairing simulation of damaged trabecula based on mathematical model for bone remodeling.
Yoshitaka Kameo, Taiji Adachi, Masaki Hojo
World Congress on Biomechanics(WCB2010)(2010.8.1-6 Singapore)      2010   [Refereed]
Quantitative evaluation of mechanical \nbehaviors of actin filament under different mechanical conditions
Shinji Matsushita, Taiji Adachi, Yasuhiro Inoue, Masaki Hojo, Masahiro Sokabe
World Congress on Biomechanics (WCB2010)(2010.8.1-6 Singapore)      2010   [Refereed]
Theoretical study on mechanochemical modulation of binding between \nactin and its accessory proteins :
Yasuhiro Inoue, Taiji Adachi, Masaki Hojo
A thermodynamics perspective. World Congress on Biomechanics(WCB 2010)(2010.8.1-6 Singapore)      2010   [Refereed]
Morphological changes in cancellous bone predicted by trabecular \nremodeling simulation considering interstitial fluid flow
Yoshitaka Kameo, Taiji Adachi, Masaki Hojo
The 17th Congress of the European Society of Biomechanics(ESB2010)(2010.7.5-8 Edinburgh, UK)      2010   [Refereed]
Orthodontic tooth movement simulation \nusing ct image-based human lower second premolar models.
Masakazu Hasegawa, Taiji Adachi, Masaki Hojo, Teruko Takano-Yamamoto
VPH2010(Virtual Physiological Human) (2010.9.30-10.1 Brussels, Belgium)      2010   [Refereed]
Mechanical detection of interaction between actin and Arp2/3 complex using \nAFM.
Sung-Woong Han, Taiji Adachi
20th Anniversary World Congress on Biosensors(Biosensors 2010)(2010.5.26-28 Glasgow, UK)      2010   [Refereed]
Mechanical regulation of actin network dynamics in migrating cells : in vitro and in silico studies.
Taiji Adachi
Seminar at Pusan National University(2010.10.7-9 Pusan, Korea)      2010   [Refereed]
Evaluation of anisotropic deformation and \nfracture propertiesin extruded HAP/PLLA composites
M. Tanaka, H. Tanaka, M. Hojo, T. Adachi, S.H. Hyon ,M. Konda
13th European Conference on Composite Materials (2008.6.2-5. Stockholm)      2008   [Refereed]
Microscale Simulation \nof Resin-Air Flow around Single Fibers.
Yasuhiro Inoue, Michihito Matsumoto, Masaki Hojo, Kazuki Ishida, Naoki Takada, Taiji Adachi
10th International Conference on Flow Processes in Composite Materials(FPCM10)(2010.7.11-15 Ascona, Switzerland)      2010   [Refereed]
T. Adachi; Y. Tomita; M. Tanaka
American Society of Mechanical Engineers, Bioengineering Division (Publication) BED   35 95-96   Dec 1997
Modeling and simulation of dynamic reconstructing network of stress fibers with \nmechanical sensing through focal adhesions.
Yasuhiro Inoue, Taiji Adachi
日本生物物理学会第48 回年会(2010.9.20-22 仙台)      2010   [Refereed]
Shigeo Wada, Yasuyuki Seguchi, Masao Tanaka, Mitsumasa Matsuda, Taiji Adachi, Motoharu Fujigaki
JSME International Journal, Series 1: Solid Mechanics, Strength of Materials   35 170-178   Apr 1992
Gas flow in the airway and lung deformation due to tissue elasticity and surface tension are the main characteristics of respiratory dynamics. In this study, a simulation with the discretized model as a distributed parameter system is used extensi...
Tensile force suppresses torsional \nmotions of individual actin subunits
Shinji Matsushita, Yasuhiro Inoue, Masaki Hojo, Masahiro Sokabe, Taiji Adachi
日本生物物理学会第48 回年会(2010.9.20-22 仙台)      2010   [Refereed]
Spatial scale-dependent correlations between cell peripheral activity and shape.
Hiromi Miyoshi, Taiji Adachi
日 本生物物理学会第48 回年会(2010.9.20-22 仙台)      2010   [Refereed]
Multiscale characteristics of protrusion and retraction activities in lamellipodium.
Hiromi Miyoshi, Taiji Adachi
The 4th Mechanobiology Workshop and Biophysical Society Joint Meeting(2010.11.9-11 Singapore)      2010   [Refereed]
Development of method for measuring tension generated \nin cytoskeleton.
Shukei Sugita, Taiji Adachi, Yosuke Ueki, Masaaki Sato
第49 回日本生体医工学会大会(2010.6.25-27 大阪)      2010   [Refereed]
Modeling of mechanosensing and intercellular communications by \nosteocytes in trabecular bone adaptation.
Taiji Adachi, Yoshitaka Kameo, Masaki Hojo
IV European Conference on Computational mechanics(ECCM 2010)(2010.5.16-21 Paris, France)(Keynote Talk)      2010   [Refereed]
Quantitative \nanalysis of lamellipodial protrusion dynamics on a micropatterning substrate.
Taiji Adachi, Masuzo Nagasaki, Kennedy O. Okeyo, Junko Sunaga, Masaki Hojo, Hidetoshi Kotera
第49 回日本生体医工学会大 会,シンポジウム「デバイス技術による細胞解析・制御の最前線」(2010.6.25-27 大阪)      2010   [Refereed]
Modeling of osteocyte mechanosensing and communication in bone adaptation.
Taiji Adachi
Symposium : Cellular Mechanics in Embryogenesis, 43rd Annual Meeting for the Japanese Society of Developmental Biologists (2010.06.20-23 Kyoto)      Jun 2010   [Refereed]
Biomechanics of actin cytoskeleton : in vitro and in silico studies
Taiji Adachi
次世代生命体統合シミュレーション研究,脳神経系チームセミナー(2010.09.29 宇治)      Sep 2010   [Refereed]
Interaction Measurement of Actin Filament and Actin Binding Protein Using \nan AFM.XIII.
Sung-Woong Han, Taiji Adachi
Annual Linz Winter Workshop Advances in Single-Molecule Research for Biology & Nanoscience(2011.2.4-7 Linz, Switzerland)      2011   [Refereed]
Quantitative analysis of the responses of migratory cells to microstructured surfaces
Hiromi Miyoshi,Jungmyoung Ju,Yutaka Yamagata,Sang Min Lee,Dong Jin Cho,Jong Soo Ko,Taiji Adachi
第63回日本細胞生物 学会(2011.6.27-29 札幌)      2011   [Refereed]
Mathematical Modeling of Trabecular Bone Remodeling Induced by Osteocytic \nResponse to Interstitial Fluid Flow
Yoshitaka Kameo, Taiji Adachi
8th European Conference on Mathematical and Theoretical Biology, and Annual Meeting of the Society for Mathematical Biology(ECMTB2011)(2011.6.28-7.2 Krakow, Poland).      2011   [Refereed]
Extension-torsion Coupling Behavior of Single Actin Filament.
Shinji Matsushita, Yasuhiro Inoue, Masahiro Sokabe, Taiji Adachi
第49 回日本生物物理学会年会(2011.9.16-18 姫路).      2011   [Refereed]
Analysis of the Contribution of the Actin Cytoskeletal Structure to Cell Migration in Controlled Microenvironments
Hiromi Miyoshi, Jungmyoung Ju, Taiji Adachi, Sang Min Lee, Dong Jin Cho, Jong Soo Ko, Yutaka Yamagata:
第49 回日本生物物理学会年会(2011.9.16-18 姫路).      2011   [Refereed]
Microscale Flow Analysis in Bone \nCanaliculi Using High-resolution Image-based Models
Taiji Adachi, Yoshitaka Kameo, Jenneke Klein-Nulend, Hiroshi Kamioka
Workshop: Microscale Modeling in Biomechanics and Mechanobiology(2011.5.30-6.1 Ericeira, Prtugal)(Invited Talk)      2011   [Refereed]
Computer Simulation of Bone Remodeling and Regeneration for Porous Scaffold Design.
Taiji Adachi
International Conference on Tissue Engineering(ICTE2011)(2011.6.2-4 Lisbon, Portugal)(Keynote)      2011   [Refereed]
Poroelastic Modelling of Trabecular Bone Adaptation Stimulated \nby Flow-induced Shear Stress on Osteocytic Process Membrane in Lacuno-canalicular System.
Taiji Adachi, Yoshitaka Kameo, Masaki Hojo
IV International Conference on Computational Methods for Coupled Problems in Science and Engineering (Coupled Problem 2011)(2011.6.20-22 Kos Island, Greece)(Keynote Lecture)      2011   [Refereed]
Effect of Tension on the Stiffness of Actin \nFilaments.
Shinji Matsushita, Yasuhiro Inoue, Masahiro Sokabe, Taiji Adachi
International Symposium on Mechanobiology(2011.11.4-8 Shanghai, China).      2011   [Refereed]
Effect of Cellsubstrate \nInteractions and Actomyosin Contractility on Lamellipodial Protrusion Dynamics on a Microstamped \nSurface.
Taiji Adachi, Kennedy O. Okeyo, Masuzo Nagasaki, Junko Sunaga, Masaki Hojo, Hidetoshi Kotera
International Symposium on Mechanobiology(2011.11.4-8 Shanghai, China)(Invited).      2011   [Refereed]

Books etc

 
Residual Stress in Bone Structure: Experimental Observation and Model Study with Uniform Stress Hypothesis
Masao Tanaka, Taiji Adachi
Biomechanics - Functional Adaptation and Remodeling,(Eds. Kozaburo Hayashi, Akira Kamiya, and Keiro Ono), pp.169-184, Springer, Tokyo.   Feb 1996   
Model and Simulation of Bone Remodeling Considering Residual Stress
Masao Tanaka, Taiji Adachi
Computational Biomechanics(Eds. Kozaburo Hayashi and Hiromasa Ishikawa), pp. 3-21, Springer, Tokyo.   Feb 1996   
Lattice Continuum Model for Bone Remodeling Considering Microstructural Optimality of Trabecular Architecture
安達 泰治
Synthesis in Bio Solid Mechanics, (Eds. P. Pedersen and M. P. Bendsoe), Kluwer Academic Publishers.,43-54   1998   
Surface Remodeling Simulation of Trabecular Bone Using Microstructural Finite Element Models
安達 泰治
Synthesis in Bio Solid Mechanics, (Eds. P. Pedersen and M. P. Bendsoe), Kluwer Academic Publishers.,309-320   1998   
Nonaffine Network Model for Glassy Polymer and Prediction of Instability Propagation
安達 泰治
Material Instability in Solids, (Eds. R. de Borst and E. van der Giessen), John Wiley & Sons Ltd.,303-321   1998   

Conference Activities & Talks

 
Hiromi Miyoshi, Kensuke Suzuki, Jungmyoung Ju, Jong Soo Ko, Taiji Adachi, Yutaka Yamagata
Analytical Sciences   1 Jan 2016   
© Japan Society for Analytical Chemistry. Migrating cells in vivo monitor the physiological state of an organism by integrating the physical as well as chemical cues in the extracellular microenvironment, and alter the migration mode, in order to ...
D. Tawara, K. Nagura, T. Tsujikami, T. Adachi
IFMBE Proceedings   1 Jan 2014   
© Springer International Publishing Switzerland 2014. Mechanical bone quality and its related loadsupporting function at the macro-scale is a result of adaptation, which is achieved by trabecular bone remodeling at the microscale. The increase in ...
Takafumi Ogawa, Takao Shimayoshi, Naoki Kida, Taiji Adachi, Tetsuya Matsuda
Transactions of Japanese Society for Medical and Biological Engineering   1 Jan 2014   
© 2014, Japan Soc. of Med. Electronics and Biol. Engineering. All rights reserved. In standard finite element analysis in structural dynamics, meshing can affect computation results. However, there have been no detailed report about effects of mes...
S. Patriche; S. Matsushita; M. Banu; B.I. Epureanu; T. Adachi
Proceedings of SPIE - The International Society for Optical Engineering   23 May 2011   
This work is concerned with the dynamics of motor proteins. In particular, we discuss the development of computational analysis tools for predicting the dynamics of molecular motors such as certain types of kinesin. The ability to model and predic...

Research Grants & Projects

 
Mechanical Adaptation of Bone by Remodeling
Residual Stress in Living Tissues
Effect of Mechanical Stimulus on Osteoblasts in vitro