2008年8月
Renal pathology of ANCA-related vasculitis: proposal for standardization of pathological diagnosis in Japan
CLINICAL AND EXPERIMENTAL NEPHROLOGY
- 巻
- 12
- 号
- 4
- 開始ページ
- 277
- 終了ページ
- 291
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1007/s10157-008-0052-7
- 出版者・発行元
- SPRINGER
Background In Japan, systematic evaluation of the histologic parameters of anti-neutrophil cytoplasmic auto-antibodies ( ANCA)-related vasculitis has been performed according to the Japanese classification by Shigematsu et al. However, this classification is quite different from that of the European Vasculitis Study Group (EUVAS) classification. Therefore, a histological common basis is needed to compare Japanese histological data with the international database.
Method Histological parameters concerning glomerular, tubulointerstitial, and vascular lesions of ANCA-related vasculitis, which are indispensable for clinical management, were elucidated and defined by reviewing, utilizing the merits of, and amending the two scoring systems.
Results and conclusion A new comprehensive and standardized scoring system, by which histological quantitative assessment can provide evidence for therapy planning, has been developed for renal biopsy of Japanese ANCA-related vasculitis.
Method Histological parameters concerning glomerular, tubulointerstitial, and vascular lesions of ANCA-related vasculitis, which are indispensable for clinical management, were elucidated and defined by reviewing, utilizing the merits of, and amending the two scoring systems.
Results and conclusion A new comprehensive and standardized scoring system, by which histological quantitative assessment can provide evidence for therapy planning, has been developed for renal biopsy of Japanese ANCA-related vasculitis.
- リンク情報
- ID情報
-
- DOI : 10.1007/s10157-008-0052-7
- ISSN : 1342-1751
- Web of Science ID : WOS:000258846900007