Papers

Peer-reviewed
Dec 1, 2018

Neurolymphomatosis in the Cauda Equina Diagnosed by an Open Biopsy.

Internal medicine (Tokyo, Japan)
  • Ryo Sasaki
  • Yasuyuki Ohta
  • Yuto Yamada
  • Koh Tadokoro
  • Yoshiaki Takahashi
  • Kota Sato
  • Jingwei Shang
  • Mami Takemoto
  • Nozomi Hishikawa
  • Toru Yamashita
  • Takao Yasuhara
  • Isao Date
  • Shuntaro Ikegawa
  • Nobuharu Fujii
  • Koji Abe
  • Display all

Volume
57
Number
23
First page
3463
Last page
3465
Language
English
Publishing type
Research paper (scientific journal)
DOI
10.2169/internalmedicine.1049-18

Neurolymphomatosis is a rare form of extranodal malignant lymphoma defined as the infiltration of malignant lymphocytes into the central or peripheral nerve. We herein report a case of neurolymphomatosis in the cauda equina diagnosed by an open surgical biopsy. He presented with muscle weakness, atrophy, numbness and hypoesthesia in the bilateral lower extremities with the accumulation of 18fluoro-2-deoxyglucose (FDG) in the bilateral cauda equina. Cerebrospinal fluid cytology (three times) and flow cytometry (two times) and biopsies of the left sural nerve, bone marrow, paranasal sinus and left testis were all negative for malignancy, so finally we performed a surgical open biopsy of the cauda equina by laminectomy and diagnosed him with diffuse large B-cell lymphoma in the cauda equina. He was successfully treated with the disappearance of the FDG accumulation for a long time. The present case suggested that an early open biopsy of the cauda equina may be considered for cases of suspected neurolymphomatosis in the cauda equina for a good outcome.

Link information
DOI
https://doi.org/10.2169/internalmedicine.1049-18
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/30101916
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306530
ID information
  • DOI : 10.2169/internalmedicine.1049-18
  • Pubmed ID : 30101916
  • Pubmed Central ID : PMC6306530

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