In sequencing problems for mixed-model assembly line in JIT production system, the Goal Chasing method (GC) is widely used for parts used leveling goal. The difference in assembly time of each product is not taken into consideration in the Goal Chasing method. Assembly time usually varies with product types. In recent years, the Time-Based Goal Chasing method (TBGC) has been proposed. The advantage of TBGC is to consider the influence of different assembly time of each product and idle time in production period. TBGC, however, has been only applied to single work station problems. In this paper, TBGC is applied to an assembly line problem with multiple work stations. Furthermore, the sequencing method and use of Simulated Annealing (SA) or Local Search (LS) for this problem are proposed.