2010年10月
Visible light-induced crosslinkable gelatin
ACTA BIOMATERIALIA
- 巻
- 6
- 号
- 10
- 開始ページ
- 4005
- 終了ページ
- 4010
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/j.actbio.2010.05.018
- 出版者・発行元
- ELSEVIER SCI LTD
A novel visible light-crosslinkable porcine gelatin was prepared for gelation and micropatterning The preparation employed a photo-oxidation-induced crosslinking mechanism. First, furfuryl groups were incorporated into the gelatin Second, the modified gelatin was mixed in water with Rose Bengal, which is a visible light sensitizer. Irradiation by visible light solidified the aqueous solution. In addition, when the solution was cast on a plate, dried and photo-irradiated in the presence of a photomask a micropattern was formed that matched the micropattern on the photomask The gelatin-immobilized regions enhanced cell adhesion. It was also confirmed that the gelatin incorporating furfuryl and Rose Bengal have no significant toxicity. The photo-crosslinkable gelatin was employed as a direct pulp capping material in the dental field. Considering these results, this system could be useful as a new type of visible light-induced crosslinkable biosealant. (C) 2010 Acta Materialia Inc. Published by Elsevier Ltd. All lights reserved.
- リンク情報
- ID情報
-
- DOI : 10.1016/j.actbio.2010.05.018
- ISSN : 1742-7061
- eISSN : 1878-7568
- Web of Science ID : WOS:000282207100020