論文

査読有り
2013年8月

The distribution of galanin-immunoreactive nerve fibers in the rat pharynx

Neuropeptides
  • Toshihiko Suzuki
  • ,
  • Tadasu Sato
  • ,
  • Mitsuhiro Kano
  • ,
  • Hiroyuki Ichikawa

47
4
開始ページ
231
終了ページ
236
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.npep.2013.05.001

Galanin (GAL) consists of a chain of 29/30 amino acids which is widely distributed in the central and peripheral nervous systems. In this study, the distribution of GAL-immunoreactive (-IR) nerve fibers was examined in the rat pharynx and its adjacent regions. GAL-IR nerve fibers were located beneath the epithelium and taste bud-like structure of the pharynx, epiglottis, soft palate and larynx. These nerve fibers were abundant in the laryngeal part of the pharynx, and were rare in other regions. Mucous glands were mostly devoid of GAL-IR nerve fibers. In the musculature of pharyngeal constrictor muscles, many GAL-IR nerve fibers were also located around small blood vessels. However, intrinsic laryngeal muscles contained only a few GAL-IR nerve fibers. The double immunofluorescence method demonstrated that the distribution pattern of GAL-IR nerve fibers was partly similar to that of calcitonin gene-related peptide-IR nerve fibers in the pharyngeal mucosa and muscles. The present findings suggest that the pharynx is one of main targets of GAL-containing nerves in the upper digestive and respiratory systems. These nerves may have sensory and autonomic origins. © 2013 Elsevier Ltd.

リンク情報
DOI
https://doi.org/10.1016/j.npep.2013.05.001
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/23731834
Scopus
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84879780565&origin=inward
Scopus Citedby
https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84879780565&origin=inward
ID情報
  • DOI : 10.1016/j.npep.2013.05.001
  • ISSN : 0143-4179
  • ISSN : 1532-2785
  • eISSN : 1532-2785
  • PubMed ID : 23731834
  • SCOPUS ID : 84879780565

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