2015
Effect of sintering time of CaTiO<inf>3</inf>–CaCO<inf>3</inf> in osteoblastic response of KUSA/A1 cells
IFMBE Proceedings
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- Volume
- 49
- Number
- First page
- 159
- Last page
- 162
- Language
- English
- Publishing type
- Research paper (international conference proceedings)
- DOI
- 10.1007/978-3-319-13117-7_42
- Publisher
- SPRINGER INT PUBLISHING AG
In recent years, calcium titanate (CaTiO3) and carbon-containing materials have gained much attention in a number of biomedical material researches. To maximize the advantages of both materials, we developed a novel alkoxide method to get ‘‘calcium titanate with calcium carbonate’’ (CaTiO3–CaCO3). Thus, our previous result indicated that calcium carbonate could play a key role in the cell response of CaTiO3 material. In the present study we evaluated the effect of sintering time of CaTiO3–CaCO3 in osteoblastic response of KUSA/A1 cells. We examined the material characterization as well as cellular proliferation and mineralization of KUSA/A1 cells cultured with the materials. The results showed that Ca-TiO3–CaCO3 material sintered during 30 min, has better influ-ence on the bone marrow stromal cells for their proliferation and mineralization compared to CaTiO3-CaCO3 sintered at 2 and 10 h. These results suggest that sintering time could be directly related to the amount of carbon within CaCO3 being crucial in cell response. In conclusion, our preliminary find-ings indicate that CaTiO3–CaCO3 could play a more dominant and favorable effect on cell response when sintered for 30 minutes.
- Link information
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- DOI
- https://doi.org/10.1007/978-3-319-13117-7_42
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000363767200041&DestApp=WOS_CPL
- Scopus
- https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84925277703&origin=inward
- Scopus Citedby
- https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84925277703&origin=inward
- ID information
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- DOI : 10.1007/978-3-319-13117-7_42
- ISSN : 1680-0737
- SCOPUS ID : 84925277703
- Web of Science ID : WOS:000363767200041