2006年4月
ASIC3-immunoreactive neurons in the rat vagal and glossopharyngeal sensory ganglia
BRAIN RESEARCH
- ,
- ,
- ,
- ,
- ,
- 巻
- 1081
- 号
- 開始ページ
- 150
- 終了ページ
- 155
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/j.brainres.2006.01.039
- 出版者・発行元
- ELSEVIER SCIENCE BV
ASIC3-immunoreactivity (ir) was examined in the rat vagal and glossopharyngeal sensory ganglia. In the jugular, petrosal and nodose ganglia, 24.8%, 30.8% and 20.6% of sensory neurons, respectively, were immunoreactive for ASIC3. These neurons were observed throughout the ganglia. A double immuno fluorescence method demonstrated that many ASIC3-immunoreactive (ir) neurons co-expressed calcitonin gene-related peptide (CGRP)- or vanilloid receptor subtype 1 (VRL-1)-ir in the jugular (CGRP, 77.8%; VRL-1, 28.0%) and petrosal ganglia (CGRP, 61.7%; VRL-1, 21.5%). In the nodose ganglion, however, such neurons were relatively rare (CGRP, 6.3%; VRL-1, 0.4%). ASIC3-ir neurons were mostly devoid of tyrosine hydroxylase in these ganglia. However, some ASIC3-ir neurons co-expressed calbindin D28k in the petrosal (5.5%) and nodose ganglia (3.8%). These findings may suggest that ASIC3-containing neurons have a wide variety of sensory modalities in the vagal and glossopharyngeal sensory ganglia. (c) 2006 Elsevier B.V. All rights reserved.
- リンク情報
- ID情報
-
- DOI : 10.1016/j.brainres.2006.01.039
- ISSN : 0006-8993
- Web of Science ID : WOS:000237098900018