2010年2月
Polycyclic N-heterocyclic compounds. Part 61: A novel Truce-Smiles type rearrangement reaction of 4-(2-cyanovinyloxy)butanenitriles to give cycloalkeno[1,2-d]furo[2,3-b]pyridines
TETRAHEDRON LETTERS
- ,
- ,
- ,
- 巻
- 51
- 号
- 6
- 開始ページ
- 903
- 終了ページ
- 906
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/j.tetlet.2009.12.010
- 出版者・発行元
- PERGAMON-ELSEVIER SCIENCE LTD
The cycloalkeno[1,2-d]furo[2,3-b]pyridine skeleton was conveniently synthesized from fused 4-(2-cyanovinyloxy)butanenitriles in one step through sequential intramolecular Michael addition, p-elimination and intramolecular nucleophilic addition. This sequence thus consists of a novel Truce-Smiles type rearrangement followed by cyclization. The 5-amino derivatives were transformed further to lactams in good yields. (C) 2009 Elsevier Ltd. All rights reserved.
- リンク情報
- ID情報
-
- DOI : 10.1016/j.tetlet.2009.12.010
- ISSN : 0040-4039
- Web of Science ID : WOS:000274710200005