北村繁幸 (Shigeyuki Kitamura) - マイポータル - researchmap

基本情報

所属: 旧所属広島大学大学院医歯薬学総合研究科助教授

学位: 薬学博士(九州大学)

J-GLOBAL ID: 200901054560426853
researchmap会員ID: 1000036330

研究分野

2

経歴

4

1980年 - 1993年

広島大学助手
1980年 - 1993年

Hiroshima University, Research Assistant
1993年

- 広島大学助教授
1993年

- Hiroshima University, Associate Professor

学歴

4

受賞

1

1982年

第2回薬学研究奨励財団研究助成金

MISC

253

Enzymatic and non-enzymatic reduction of brucine N-oxide by aldehyde oxidase and catalase

K Takekawa, K Sugihara, S Kitamura, S Ohta

XENOBIOTICA 31(11) 769-782 2001年11月
Extremely high drug-reductase activity based on aldehyde oxidase in monkey liver

S Kitamura, K Nakatani, K Ohashi, K Sugihara, R Hosokawa, Y Akagawa, S Ohta

BIOLOGICAL & PHARMACEUTICAL BULLETIN 24(7) 856-859 2001年7月
Aryl hydrocarbon receptor (AhR)-mediated induction of xanthine oxidase/xanthine dehydrogenase activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin

K Sugihara, S Kitamura, T Yamada, S Ohta, K Yamashita, M Yasuda, Y Fujii-Kuriyama

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 281(5) 1093-1099 2001年3月
Aryl Hydrocarbon Receptor(AhR)-Mediated Induction of Xanthine Oxidase/Xanthine Dehydrogenase Activity by 2, 3, 7, 8-Tetrachlorodibenzo-(p)■.-.-dioxin.

SUGIHARA K, KITAMURA S, YAMADA T, OHTA S, YAMASHITA K, YASUDA M, FUJII‐KURIYAMA Y

Biochemical and Biophysical Research Communications 281(5) 1093-1099 2001年3月
Metabolism of 2-nitrofluorene, an environmental pollutant, and 2-acetylaminofluorene in fish

O Ueda, S Kitamura, Y Huruse, T Saito, Y Kanzaki, Y Yano, K Tatsumi, S Ohta

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 66(3) 371-378 2001年3月
Non-enzymatic reduction of aliphatic tertiary amine N-oxides mediated by the haem moiety of cytochrome P450

K Takekawa, S Kitamura, K Sugihara, S Ohta

XENOBIOTICA 31(1) 11-23 2001年1月
Metabolism of 2-Nitrofluorene, 2-Aminofluorene and 2-Acetylaminofluorene in Rat and Dog and the Role of Intestinal Bacteria

UEDA O, KITAMURA S, KUBO R, YANO Y, KANZAKI Y, FUJIMOTO T, TATSUMI K, OHTA S

Xenobiotica 31(1) 33-39 2001年
Nonenzymatic Reduction of Aliphatic Tertiary Amine (N)■.-.-Oxides Mediated by the Heme Moiety of Cytochrome P450.

Xenobiotica 31(1) 11-23 2001年1月
Metabolism of 2-Nitrofluorene, 2-Aminofluorene and 2-Acetylaminofluorene in Rat and Dog and the Role of Intestinal Bacteria.

UEDA O, KITAMURA S, KUBO R, YANO Y, KANZAKI Y, FUJIMOTO T, TATSUMI K, OHTA S

Xenobiotica 31(1) 33-39 2001年
Aryl hydrocarbon receptor (AhR)-mediated induction of xanthine oxidase/xanthine dehydrogenase activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin

Kazumi Sugihara, Shigeyuki Kitamura, Tuyoshi Yamada, Shigeru Ohta, Keisuke Yamashita, Mineo Yasuda, Yoshiaki Fujii-Kuriyama

Biochemical and Biophysical Research Communications 281(5) 1093-1099 2001年
Nonenzymatic Reduction of Aliphatic Tertiary Amine N-Oxides Mediated by the Heme Moiety of Cytochrome P450

Xenobiotica 31(1) 11-23 2001年
Metabolism of 2-Nitrofluorene, 2-Aminofluorene and 2-Acetylaminofluorene in Rat and Dog and the Role of Intestinal Bacteria

Xenobiotica 31(1) 33-39 2001年
Non-enzymatic reduction of aliphatic tertiary amine N-oxides mediated by the haem moiety of cytochrome P450

K. Takekawa, S. Kitamura, K. Sugihara, S. Ohta

Xenobiotica 31(1) 11-23 2001年
Metabolism of 2-Nitrofluorene, 2-Aminofluorene and 2-Acetylaminofluorene in Rat and Dog and the Role of Intestinal Bacteria.

Xenobiotica 31(1) 33-39 2001年
Aryl Hydrocarbon Receptor(AhR)-Mediated Induction of Xanthine Oxidase/Xanthine Dehydrogenase Activity by 2, 3, 7, 8-Tetrachlorodibenzo-(p)■.-.-dioxin.

Biochemical and Biophysical Research Communications 281(5) 1093-1099 2001年
Metabolic activation of the proestrogens trans-stilbene and trans-stilbene oxide by rat liver microsomes

Kazumi Sugihara, Shigeyuki Kitamura, Seigo Sanoh, Shigeru Ohta, Nariaki Fujimoto, Satoshi Maruyama, Akihiro Ito

Toxicology and Applied Pharmacology 167(1) 46-54 2000年8月15日
Metabolic Activation of the Proestrogens (trans)■.-.-Stilbene and (trans)■.-.-Stilbene Oxide by Rat Liver Microsomes.

SUGIHARA K, KITAMURA S, SANOH S, OHTA S, FUJIMOTO N, MARUYAMA S, ITO A

Toxicology and Applied Pharmacology 167(1) 46-54 2000年8月
Metabolic activation of the proestrogens trans-stilbene and trans-stilbene oxide by rat liver microsomes

K Sugihara, S Kitamura, S Sanoh, S Ohta, N Fujimoto, S Maruyama, A Ito

TOXICOLOGY AND APPLIED PHARMACOLOGY 167(1) 46-54 2000年8月
Reduction of hydroxamic acids to the corresponding amides catalyzed by rabbit blood

K Sugihara, S Kitamura, S Ohta, K Tatsumi

XENOBIOTICA 30(5) 457-467 2000年5月
Cynomolgus monkey liver aldehyde oxidase: extremely high oxidase activity and an attempt at purification

K Sugihara, Y Katsuma, S Kitamura, S Ohta, M Fujitani, H Shintani

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 126(1) 53-60 2000年5月

もっとみる

書籍等出版物

5

現代医療：キーとなる臨床検査内分泌撹乱化学物質の検査

株式会社現代医療社 2001年
ファルマシア：エストロゲン合成におけるチトクロームＰー450による芳香環化機構

日本薬学会 1994年
薬学研究の進歩：薬物代謝に関与する新電子伝達系

薬学研究奨励財団 1985年
IUPAC Pesticide Chemistry: Human Welfare and the Environment 'Bioactivation Involving Nitrogen-Containing Substituents'

Pergamon Press 1983年
IUPAC Pesticide Chemistry: Human Welfare and the Environment 'Bioactivation Involving Nitrogen-Containing Substituents'

Pergamon Press 1983年

Works(作品等)

2

抗炎症薬の代謝研究

1993年 - 1994年
Metabolism of anti-inflammatory agent

1993年 - 1994年

共同研究・競争的資金等の研究課題

6