鈴木裕 (Hiroshi Suzuki) - マイポータル - researchmap

基本情報

所属: 旭川医科大学医学部医学科生化学講座機能分子科学分野教授

学位: 理学博士(東京工業大学)

J-GLOBAL ID: 200901063124055130
researchmap会員ID: 1000047353

外部リンク: http://www.asahikawa-med.ac.jp/dept/mc/biochem2/

研究キーワード

4

研究分野

4

経歴

11

1993年 - 1999年

旭川医科大学助教授
1993年 - 1999年

旭川医科大学
1989年 - 1993年

旭川医科大学講師
1989年 - 1993年

旭川医科大学
1985年 - 1989年

旭川医科大学助手
1985年 - 1989年

旭川医科大学
1981年 - 1985年

Boston Biomedical Research Institute 研究員
1981年 - 1985年

Boston Biomedical Research Institute,
Assistant Professor
Research Assistant
Research Associate

学歴

4

委員歴

1

2002年

日本生化学会, 評議員

MISC

58

Comprehensive analysis of expression and function of 51 sarco(endo) plasmic reticulum Ca2+-ATPase mutants associated with Darier disease

Yuki Miyauchi, Takashi Daiho, Kazuo Yamasaki, Hidetoshi Takahashi, Akemi Ishida-Yamamoto, Stefania Danko, Hiroshi Suzuki, Hajime Iizuka

JOURNAL OF BIOLOGICAL CHEMISTRY 281(32) 22882-22895 2006年8月
Comprehensive analysis of expression and function of 51 sarco(endo) plasmic reticulum Ca2+-ATPase mutants associated with Darier disease

Yuki Miyauchi, Takashi Daiho, Kazuo Yamasaki, Hidetoshi Takahashi, Akemi Ishida-Yamamoto, Stefania Danko, Hiroshi Suzuki, Hajime Iizuka

JOURNAL OF BIOLOGICAL CHEMISTRY 281(32) 22882-22895 2006年8月
ATP2C1 is specifically localized in the basal layer of normal epidermis and its depletion triggers keratinocyte differentiation

M Yoshida, K Yamasaki, T Daiho, H Iizuka, H Suzuki

JOURNAL OF DERMATOLOGICAL SCIENCE 43(1) 21-33 2006年7月
Critical hydrophobic interactions between phosphorylation and actuator domains of Ca2+-ATPase for hydrolysis of phosphorylated intermediate

GL Wang, K Yamasaki, T Daiho, H Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 280(28) 26508-26516 2005年7月
Analysis of Ca²⁺-release process in the phosphorylated intermediates of sarcoplasmic reticulum Ca²⁺-ATPase by mutagenesis

生化学 77(8) 804 2005年
Ca²⁺ occlusion and de-occlusion at transport sites of phosphoenzyme intermediates of sarcoplasmic reticulum Ca²⁺-ATPase studied by mutagenesis

生化学 77(8) 803 2005年
Ca²⁺ポンプのドメイン間相互作用変化とエネルギー変換

鈴木裕

生物物理 45(1) 16-21 2005年
Changes in Cytoplasmic Domain Organization and Energy Transduction in Calcium Pump

Hiroshi SUZUKI

SEIBUTSU BUTSURI 45(1) 16-21 2005年
Distinct types of abnormality in kinetic properties of three Darier disease-causing sarco(endo)plasmic reticulum Ca2+-ATPase mutants that exhibit normal expression and high Ca2+ transport activity

K Sato, K Yamasaki, T Daiho, Y Miyauchi, H Takahashi, A Ishida-Yamamoto, S Nakamura, H Iizuka, H Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 279(34) 35595-35603 2004年8月
Multiple and Distinct Effects of Mutations of Tyr¹²², Glu¹²³, Arg³²⁴, and Arg³³⁴ Involved in Interactions between the Top Part of Second and Fourth Transmembrane Helices in Sarcoplasmic Reticulum Ca^{2+</s・・・}

YAMASAKI K, DAIHO T, DANKO S, SUZUKI H

The Journal of Biological Chemistry 279(3) 2202-2210 2004年
Distinct Natures of Be/F-bound, and Mg/F-bound Stable Analogues of ADP-insensitive Phosphoenzyme Intermediate of Sarcoplasmic Reticulum Ca2+ -ATPase.

The Journal of Biological Chemistry 279(15) 14991-14998 2004年
Multiple and Distinct Effects of Mutations of Tyr¹²², Gla¹²³, Arg³²⁴, and Arg³³⁴ Involved in Interactions between the Top Part of Second and Fourth Transmembrane Helices in Sarcoplasmic Reticulum Ca^{2+</s・・・}

YAMASAKI K, DAIHO T, DANKO S, SUZUKI H

The Journal of Biological Chemistry 279(3) 2202-2210 2004年
Multiple and Distinct Effects of Mutations of Tyr¹²², Glu¹²³, Arg³²⁴, and Arg³³⁴ Involved in Interactions between the Top Part of Second and Fourth Transmembrane Helices in Sarcoplasmic Reticulum Ca^{2+</s・・・}

The Journal of Biological Chemistry 279(3) 2202-2210 2004年
Delections of Any Single Residues in Glu⁴⁰-Ser⁴⁸ Loop Connecting A Domain and the First Transmembrane Helix of Sarcoplasmic Reticulum Ca²⁺-ATPase Result in Almost Complete Inhibition of Conformational Transition and Hyd・・・

DAIHO T, YAMASAKI K, WANG G, DANKO S, IIZUKA H, SUZUKI H

The Journal of Biological Chemistry 278(40) 39197-39204 2003年10月
Deletions of any single residues in Glu(40)-Ser(48) loop connecting a domain and the first transmembrane helix of sarcoplasmic reticulum Ca(2+)-ATPase result in almost complete inhibition of conformational transition and hydrolysis of phosphoenzyme intermediate

T Daiho, K Yamasaki, GL Wang, S Danko, H Iizuka, H Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 278(40) 39197-39204 2003年10月
Val(200) residue in Lys(189)-Lys(205) outermost loop on the A domain of sarcoplasmic reticulum Ca2+-ATPase is critical for rapid processing of phosphoenzyme intermediate after loss of ADP sensitivity

S Kato, M Kamidochi, T Daiho, K Yamasaki, W Gouli, H Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 278(11) 9624-9629 2003年3月
A Japanese case of segmental Darier's disease Caused by mosaicism for the ATP2A2 mutation

British Journal of Dermatology 149, 185-188 2003年
Ca²⁺ポンプの構造／機能連関および遺伝子異常と細胞病態

生化学 75(9) 1215-1224 2003年
A Japanese case of segmental Darier's disease caused by mosaicism for the ATP2A2 mutation

British Journal of Dermatology 149, 185-188 2003年
Ca²⁺-induce structural changes in Ca²⁺ pump;strategy of energy coupling in cation transport.

PROTEIN, NUCLEIC ACID AND ENZYME 47(14) 1947-1948 2002年

もっとみる

書籍等出版物

7

Ca²⁺-pump.

Sensory organs and information processing in brain. Series; New century in Bioscience. Kyoritsu-syuppann/The Japanese Biochemical Society 2002年
Molecular switch in muscle contraction and relaxation; Excitation-contraction coupling.

Sport science and genetics Q&A. Taisyuukannsyotenn 2001年
Mutations of arginine-198 in sarcoplasmic reticulum Ca²⁺-ATPase cause inhibition of hydrolysis of the phosphoenzyme intermediate formed from inorganic phosphate.

The Na/K-ATPase and Related ATPases. Elsevier, North Holland 2000年
Deletions or specific substitutions of a few residents in the NH₂-terminal Ala3-Thr9 region of sarcoplasmic reticulum Ca²⁺-ATPase cause inactivation and rapid degradation of the enzyme expressed in COS-1 cells.

The Na/K-ATPase and Related ATPases. Elsevier, North Holland 2000年
Only half of the Ca²⁺-ATPase molecules present in sarcoplasmic reticulum vesicles can be phosphorylated with ATP or Inorganic phosphate.

The Na/K-ATPase and Related ATPases. Elsevier,North Holland 2000年
Conformational Changes in the Vicinity of the N-Iodoacetyl-N'-(5-sulfo-1-naphthyl)ethylenediamine Attached to the Specific Thiol of Sarcoplasmic Reticulum Ca²⁺-ATPase Through the Catalytic Cycle

JAPAN SCIENTIFIC SOCIETIES PRESS, SPRINGER-VERLAG,332-334 1988年
Conformational Changes in Myosin and Heavy Meromyosin from Chicken Gizzard Associated with Phosphorylation

Alan R. Liss, Inc. 1987年

所属学協会

3

Works(作品等)

2

筋小胞体Ca²⁺-ATPaseの構造と機能

2000年
Structure and function of sarco(endo)plasmic reticulum Ca²⁺-ATPase

2000年

共同研究・競争的資金等の研究課題

6

小胞体Ca²⁺ポンプ遺伝子異常によるダリエー病発症の分子機構

科学研究費補助金 1999年
Mechanism of Darier's disease by mutations of endoplasmic reticulum Ca²⁺-pump

Grant-in-Aid for Scientific Research 1999年
P型カチオンポンプの分子機構

科学研究費補助金 1985年
小胞体Ca²-ATPアーゼの分子作動機構

科学研究費補助金 1985年
molecular mechanism of P-type Cation Pump

Grant-in-Aid for Scientific Research 1985年
Molecular Mechanism of Sarcoendoplasmic Retifulum Ca²⁺-ATPase

Grant-in-Aid for Scientific Research 1985年