大保貴嗣 (Takashi Daiho) - マイポータル - researchmap

基本情報

所属: 旭川医科大学医学部医学科生化学講座助教授・准教授

学位: 理学博士(大阪大学)

J-GLOBAL ID: 200901043856138924
researchmap会員ID: 1000047355

外部リンク: http://www.asahikawa-med.ac.jp/dept/mc/biochem2/

研究キーワード

18

研究分野

4

経歴

6

2003年 - 2009年

旭川医科大学助教授・准教授
2003年 - 2007年

旭川医科大学
2000年 - 2003年

旭川医科大学講師
2000年 - 2003年

旭川医科大学
1988年 - 2000年

旭川医科大学助手
1988年 - 2000年

旭川医科大学

学歴

4

MISC

40

Ca2+ Release to Lumen from ADP-sensitive Phosphoenzyme E1PCa(2) without Bound K+ of Sarcoplasmic Reticulum Ca2+-ATPase

Kazuo Yamasaki, Takashi Daiho, Stefania Danko, Hiroshi Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 285(49) 38674-38683 2010年12月
Stable Structural Analog of Ca2+-ATPase ADP-insensitive Phosphoenzyme with Occluded Ca2+ Formed by Elongation of A-domain/M1 '-linker and Beryllium Fluoride Binding

Takashi Daiho, Stefania Danko, Kazuo Yamasaki, Hiroshi Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 285(32) 24538-24547 2010年8月
Roles of Interaction between Actuator and Nucleotide Binding Domains of Sarco(endo)plasmic Reticulum Ca2+-ATPase as Revealed by Single and Swap Mutational Analyses of Serine 186 and Glutamate 439

Xiaoyu Liu, Takashi Daiho, Kazuo Yamasaki, Guoli Wang, Stefania Danko, Hiroshi Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 284(37) 25190-25198 2009年9月
Formation of the Stable Structural Analog of ADP-sensitive Phosphoenzyme of Ca2+-ATPase with Occluded Ca2+ by Beryllium Fluoride STRUCTURAL CHANGES DURING PHOSPHORYLATION AND ISOMERIZATION

Stefania Danko, Takashi Daiho, Kazuo Yamasaki, Xiaoyu Liu, Hiroshi Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 284(34) 22722-22735 2009年8月
Roles of Tyr(122)-hydrophobic Cluster and K+ Binding in Ca2+-releasing Process of ADP-insensitive Phosphoenzyme of Sarcoplasmic Reticulum Ca2(+)-ATPase

Kazuo Yamasaki, Guoli Wang, Takashi Daiho, Stefania Danko, Hiroshi Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 283(43) 29144-29155 2008年10月
Critical role of glu(40)-ser(48) loop linking actuator domain and first transmembrane helix of Ca2+-ATPase in Ca2+ deocclusion and release from ADP-insensitive phosphoenzyme

Takashi Daiho, Kazuo Yamasaki, Stefania Danko, Hiroshi Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 282(47) 34429-34447 2007年11月
Comprehensive analysis of expression and function of 51 sarco(endo) plasmic reticulum Ca2+-ATPase mutants associated with Darier disease

Yuki Miyauchi, Takashi Daiho, Kazuo Yamasaki, Hidetoshi Takahashi, Akemi Ishida-Yamamoto, Stefania Danko, Hiroshi Suzuki, Hajime Iizuka

JOURNAL OF BIOLOGICAL CHEMISTRY 281(32) 22882-22895 2006年8月
ATP2C1 is specifically localized in the basal layer of normal epidermis and its depletion triggers keratinocyte differentiation

M Yoshida, K Yamasaki, T Daiho, H Iizuka, H Suzuki

JOURNAL OF DERMATOLOGICAL SCIENCE 43(1) 21-33 2006年7月
Critical hydrophobic interactions between phosphorylation and actuator domains of Ca2+-ATPase for hydrolysis of phosphorylated intermediate

GL Wang, K Yamasaki, T Daiho, H Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 280(28) 26508-26516 2005年7月
Critical hydrophobic interactions between phosphorylation and actuator domains of Ca2+-ATPase for hydrolysis of phosphorylated intermediate

J Biol Chem. 280(28) 26508-26516 2005年
Distinct types of abnormality in kinetic properties of three Darier disease-causing sarco(endo)plasmic reticulum Ca2+-ATPase mutants that exhibit normal expression and high Ca2+ transport activity

K Sato, K Yamasaki, T Daiho, Y Miyauchi, H Takahashi, A Ishida-Yamamoto, S Nakamura, H Iizuka, H Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 279(34) 35595-35603 2004年8月
Distinct natures of beryllium fluoride-bound, aluminum fluoride-bound, and magnesium fluoride-bound stable analogues of an ADP-insensitive phosphoenzyme intermediate of sarcoplasmic reticulum Ca2+-ATPase: changes in catalytic and transport sites during・・・

Danko S, Yamasaki K, Daiho T, Suzuki H

J. Biol. Chem. 279(15) 14991-14998 2004年4月
Distinct natures of beryllium fluoride-bound, aluminum fluoride-bound, and magnesium fluoride-bound stable analogues of an ADP-insensitive phosphoenzyme intermediate of sarcoplasmic reticulum Ca2+-ATPase - Changes in catalytic and transport sites during phosphoenzyme hydrolysis

S Danko, K Yamasaki, T Daiho, H Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 279(15) 14991-14998 2004年4月
Multiple and distinct effects of mutations of Tyr122, Glu123, Arg324, and Arg334 involved in interactions between the top part of second and fourth transmembrane helices in sarcoplasmic reticulum Ca2+-ATPase: changes in cytoplasmic domain organization ・・・

Yamasaki K, Daiho T, Danko S, Suzuki H

J. Biol. Chem. 279(3) 2202-2210 2004年1月16日
Multiple and distinct effects of mutations of Tyr122, Glu123, Arg324, and Arg334 involved in interactions between the top part of second and fourth transmembrane helices in sarcoplasmic reticulum Ca2+-ATPase: changes in cytoplasmic domain organization ・・・

J Biol Chem. 279(3) 2202-2210 2004年
Deletions of any single residues in Glu(40)-Ser(48) loop connecting a domain and the first transmembrane helix of sarcoplasmic reticulum Ca(2+)-ATPase result in almost complete inhibition of conformational transition and hydrolysis of phosphoenzyme intermediate

T Daiho, K Yamasaki, GL Wang, S Danko, H Iizuka, H Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 278(40) 39197-39204 2003年10月
Val(200) residue in Lys(189)-Lys(205) outermost loop on the A domain of sarcoplasmic reticulum Ca2+-ATPase is critical for rapid processing of phosphoenzyme intermediate after loss of ADP sensitivity

S Kato, M Kamidochi, T Daiho, K Yamasaki, W Gouli, H Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 278(11) 9624-9629 2003年3月
Val(200) residue in Lys(189)-Lys(205) outermost loop on the A domain of sarcoplasmic reticulum Ca2+-ATPase is critical for rapid processing of phosphoenzyme intermediate after loss of ADP sensitivity

S Kato, M Kamidochi, T Daiho, K Yamasaki, W Gouli, H Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 278(11) 9624-9629 2003年3月
Remarkable stability of solubilized and delipidated sarcoplasmic reticulum Ca2+-ATPase with tightly bound fluoride and magnesium against detergent-induced denaturation

K Yamasaki, T Daiho, H Suzuki

JOURNAL OF BIOLOGICAL CHEMISTRY 277(16) 13615-13619 2002年4月
Organization of cytoplasmic domains of sarcoplasmic reticulum Ca(2+)-ATPase in E(1)P and E(1)ATP states: a limited proteolysis study

S Danko, K Yamasaki, T Daiho, H Suzuki, C Toyoshima

FEBS LETTERS 505(1) 129-135 2001年9月

もっとみる

書籍等出版物

4

Deletions or Specific Substitutions of a Few Residues in the NH₂-terminal Ala3-Thr9 Region of Sarcoplasmic Ca²⁺-ATPase Cause Inactivation and Rapid Degradation of the Enzyme Expressed in COS-1 Cells

Excerpta Medical International Congress Series ┣DBThe Na/K-ATPase and Related ATPases(/)-┫DB Elsevier 2000年
Mutations of Arginine-198 in Sarcoplasmic Reticulum Ca²⁺-ATPase Cause Inhibition of Hydrolysis of the Phosphoenzyme Intermediate Formed from Inorganic Phosphate

Excerpta Medical International Congress Series ┣DBThe Na/K-ATPase and Related ATPases(/)-┫DB Elsevier 2000年
Only Half of the Ca²⁺-ATPase Molecules Present in Sarcoplasmic Reticulum Vesicles Can Be Phosphorylated with ATP or Inorganic Phosphate

Excerpta Medical International Congress Series ┣DBThe Na/K-ATPase and Related ATPases(/)-┫DB Elsevier 2000年
Reconstitution of Calcium Transport from Monomeric ATPase of Sarcoplasmic Reticulum

Perspectives of biological Energy Transduction Academic Press 1987年

所属学協会

3

Works(作品等)

3

ダリエー病に関連するCa²⁺-ATPase異常の研究

2000年 - 2003年
Structure and Function of Ca²⁺-ATPase

2000年 - 2001年
Darier disease ; functional analysis of Ca²⁺-ATPase disorder

2000年 - 2001年

共同研究・競争的資金等の研究課題

4