2005年2月
Highly regio- and stereoselective hydrostannylation of alkynols with a new Lewis acidic hydrostannane
ORGANIC LETTERS
- ,
- ,
- ,
- 巻
- 7
- 号
- 3
- 開始ページ
- 503
- 終了ページ
- 505
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1021/ol0474397
- 出版者・発行元
- AMER CHEMICAL SOC
Bu2Sn(OTf)H (1a), easily prepared from Bu2SnH2 and TfOH, was found to be very valuable for highly regio- and stereoselective hydrostannylation of various propargyl alcohols leading to (Z)-gamma-stannylated allyl alcohols. The stannylation with la is applicable to the synthesis of hydroxysubstituted (Z)-vinylstannanes from terminal alkynes bearing a hydroxy group at the homoallylic or bishomoallylic position. The coordination of the hydroxy group to the Lewis acidic tin center plays an important role for the observed regio- and stereochemistry.
- リンク情報
- ID情報
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- DOI : 10.1021/ol0474397
- ISSN : 1523-7060
- Web of Science ID : WOS:000226679100037