論文

査読有り
2010年1月

口腔カンジダ症に対する抗真菌薬の臨床効果の適切な判定方法に関する研究 : ―抗真菌薬の効果判定基準作成委員会報告―

歯科薬物療法
  • 中川, 洋一
  • 小根山, 隆浩
  • 寺井, 陽彦
  • 金川, 昭啓
  • 岩渕, 博史
  • 三宅, 哲
  • 長谷川, 功
  • 西川, 正典
  • 中山, 秀樹
  • 西村, 敏
  • 林田, 淳之將
  • 斎藤, 健一
  • 鬼澤, 浩司郎
  • 福田, 雅幸
  • 新美, 奏恵
  • 柴原, 孝彦
  • 神部, 芳則
  • 川又, 均
  • 鶴本, 明久
  • 佐藤, 田鶴子
  • 石橋, 克禮
  • 金子, 明寛
  • 宮坂, 孝弘
  • 上川, 善昭
  • 栗山, 智有
  • 前田, 伸子
  • 山田, 庄司
  • 佐藤, 勉
  • 池田, 文昭
  • 小林, 寅哲
  • 全て表示

30
1
開始ページ
29
終了ページ
40
記述言語
日本語
掲載種別
研究論文(学術雑誌)
DOI
10.11263/jsotp.30.29
出版者・発行元
日本歯科薬物療法学会

Purpose: The purpose of the study was to establish the response evaluation criteria of antifungal agents for oral candidiasis.Methods: A multicenter open-label trial was conducted. The patients with oral candidiasis were treated by an antifungal agent, itraconazole, and the response to the agent was evaluated according to the protocol. A multiple regression analysis was employed to examine the relative contribution of clinical signs and symptoms, including redness, white papules, atrophy of the papilla of the tongue, pain and soreness to the global evaluation of the responses judged by the attending physician. The global evaluation of the responses was rated as markedly improved, moderately improved or unchanged.Results: The multiple regression analysis showed that redness of the tongue and palate, white papules on the tongue, atrophy of the papillae of the tongue, and pain were associated with the global evaluation of the responses judged by the attending physician. Conclusion: Evaluation of these signs and symptoms could provide useful response information about antifungal therapy for oral candidiasis patients. Further studies will therefore be needed to verify the results of the

リンク情報
DOI
https://doi.org/10.11263/jsotp.30.29
ID情報
  • DOI : 10.11263/jsotp.30.29
  • ISSN : 0288-1012

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