J-GLOBAL         Last updated: Apr 4, 2019 at 02:40
University of Miyazaki
Faculty of Madicine School of Madicine Pathology course tumor and reproduction condition study field
Job title
Doctor (Medical Science)(Miyazaki Medical College)
Other affiliation
University of Miyazaki

Research Interests


Academic & Professional Experience

Oct 2015
University of Miyazaki
Aug 2001
Professor, Faculty of Madicine School of Madicine Pathology course tumor and reproduction condition study field, University of Miyazaki
Aug 1998
Jul 2001
Associate Professor (as old post name), University of Miyazaki
Oct 1988
Jul 1998
Research Assistant, University of Miyazaki
Sep 1989
Sep 1991
Researcher, Department of Anatomy and Cellular Biology, Tufts University School of Medicine


Sep 1988
Cytology and Organology Course, Graduate School, Division of Medicine, Miyazaki Medical College
Mar 1982
Medicine, Faculty of Medicine, Miyazaki Medical College

Committee Memberships

Jan 2013
Japan Human Cell Society  Editor-in-Chief, Human Cell

Published Papers

Kawaguchi M, Yamamoto K, Takeda N, Fukushima T, Yamashita F, Sato K, Kitamura K, Hippo Y, Janetka JW, Kataoka H.
Communications Biology      Jan 2019   [Refereed]
Mutations in SPINT2 encoding the epithelial serine protease inhibitor hepatocyte growth factor activator inhibitor-2 (HAI-2) are associated with congenital tufting enteropathy. However, the functions of HAI-2 in vivo are poorly understood. Here we...
Lee D, Taniguchi N, Sato K, Choijookhuu N, Hishikawa Y, Kataoka H, Morinaga H, Lotz M, Chosa E.
Scientific Reports   8(1)    Dec 2018   [Refereed]
Yamasaki K, Mukai S, Nagai T, Nakahara K, Fujii M, Terada N, Ohno A, Sato Y, Toda Y, Kataoka H, Kamoto T
International Journal of Molecular Sciences   19(12) 3708   Nov 2018   [Refereed]
Fukushima T, Kawaguchi M, Yamamoto K, Yamashita F, Izumi A, Kaieda T, Takezaki Y, Itoh H, Takeshima H, Kataoka H.
Cancer Science   109(9) 2970-2979   Sep 2018   [Refereed]
Investigation of relief effect of acute phase muscle fatigue on branched-chain amino acid (BCAA) drink “mild fermented by koji mold named HYKUBYAKUKOJI": - A randamized, open-placebo-controlled crossover study.
Takeyasu T, Arimura Y, Yonezawa Y, Fukao Y, Funamoto T, Furuichi K, Ueno H, Matsumoto N, Eto N, Kataoka H
Japanese Pharmacology and Therapeutics   46(7) 1177-1190   Jul 2018   [Refereed]


Fukushima T, Uchiyama S, Tanaka T, Kataoka H
International Journal of Molecular Sciences   19(11) 3435   Nov 2018   [Refereed][Invited]
Kataoka H, Kawaguchi M, Fukushima T, Shimomura T
Pathology International   68(3) 145-158   Mar 2018   [Refereed][Invited]
The growth, survival, and metabolic activities of multicellular organisms at the cellular level are regulated by intracellular signaling, systemic homeostasis and the pericellular microenvironment. Pericellular proteolysis has a crucial role in pr...
Haruyama Y, Kataoka H
World Journal of Gastroenterology   22(1) 275-283   Jan 2016
Ishida Y, Takeshita M, Kataoka H.
World Journal of Hepatology   6(12) 870-879   Dec 2014
Kawaguchi M, Kataoka H.
Cancers   6(4) 1890-1904   Sep 2014

Books etc

Extracellular targeting of cell signaling in cancer.
Kataoka H, Shimomura T (Part:Contributor)
Wiley   Jul 2018   ISBN:9781119300182
Kataoka H, Fukushima T (Part:Contributor)
Springer Nature   Mar 2018   ISBN:978-981-10-7295-6
Ishida Y, Yukizaki C, Okayama A, Kataoka H (Part:Joint Work)
Nova Science Publishers   Mar 2015   ISBN:978-1-63463-407-6
Handbook of Proteolytic Enzymes (Third Edition)
Kataoka H (Part:Joint Work, Chapter 660: Hepatocyte Growth Factor Activator)
Academic Press (Elsevier)   Jan 2013   ISBN:9.7801238222e+012
Molecular Targets of CNS Tumors
Fukushima T, Kataoka H (Part:Joint Work)
InTech   Sep 2011   ISBN:978-953-307-736-9

Conference Activities & Talks

Hai-2 is essential for the maintenance of intestinal epithelium in mice.
Kataoka H, Kawaguchi M, Yamamoto K, Seto A, Fukushima T, Shimomura T, Takeda N
ASBMB Special Symposia Series; Membrane-Anchored Serine Proteases   14 Sep 2017   American Society for Biochemistry and Molecular Biology
Accelerated tumor formation induced by Hai-1 deficiency in the ApcMin/+ model is prevented by concomitant deficiency of Par-2.
Kawaguchi M, Yamamoto K, Fukushima T, Camerer E, Kataoka H
ASBMB Special Symposia Series; Membrane-Anchored Serine Proteases   14 Sep 2017   American Society for Biochemistry and Molecular Biology
Loss of HAI-1 upregulates MMP-9 expression and induces degradation of epidermal basement membrane.
Kawaguchi M, Fukushima T, Kataoka H
第75回日本癌学会学術総会   6 Oct 2016   日本癌学会
Roles of a long non-coding RNA, MALAT-1, in glioblastoma.
Fukushima T, Kawaguchi M, Yamamoto K, Tanaka H, Kataoka H
第75回日本癌学会学術総会   6 Oct 2016   日本癌学会
Epigenetic regulation of HAI-2 expression in glioblastoma cells.
Fukushima T, Fujita S, Kawaguchi M, Kanemaru A, Yamamoto K, Tanaka H, Kataoka H
第38回 日本分子生物学会年会   1 Dec 2015   日本分子生物学会

Research Grants & Projects

Mechanism of tumor invasion and metastasis
The Other Research Programs
Project Year: Oct 1988 - Today
Regulation of cellular functions by integral membrane serine proteases and cognate membrane-type inhibitors
Grant-in-Aid for Scientific Research
Project Year: Apr 2000 - Today