Aug, 2010
5-HTTLPR polymorphism influences prefrontal neurochemical metabolites in autism spectrum disorder
PSYCHIATRY RESEARCH-NEUROIMAGING
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- Volume
- 183
- Number
- 2
- First page
- 170
- Last page
- 173
- Language
- English
- Publishing type
- Research paper (scientific journal)
- DOI
- 10.1016/j.pscychresns.2010.04.015
- Publisher
- ELSEVIER IRELAND LTD
We investigated whether the promoter region of the serotonin transporter gene (5-HTTLPR) polymorphism influenced neurochemical metabolism in 26 individuals with autism spectrum disorder. Individuals with the S/S genotype of the 5-HTTLPR polymorphism showed significantly lower levels of N-acetylaspartate/creatine in the right medial prefrontal cortex compared with those with the S/L genotype. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
- Link information
- ID information
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- DOI : 10.1016/j.pscychresns.2010.04.015
- ISSN : 0925-4927
- Web of Science ID : WOS:000280946700013