Papers

Peer-reviewed
Aug, 2010

5-HTTLPR polymorphism influences prefrontal neurochemical metabolites in autism spectrum disorder

PSYCHIATRY RESEARCH-NEUROIMAGING
  • Taro Endo
  • ,
  • Hideaki Kitamura
  • ,
  • Ryu Tamura
  • ,
  • Jun Egawa
  • ,
  • Takuro Sugai
  • ,
  • Naoki Fukui
  • ,
  • Yutaro Suzuki
  • ,
  • Toshiyuki Someya

Volume
183
Number
2
First page
170
Last page
173
Language
English
Publishing type
Research paper (scientific journal)
DOI
10.1016/j.pscychresns.2010.04.015
Publisher
ELSEVIER IRELAND LTD

We investigated whether the promoter region of the serotonin transporter gene (5-HTTLPR) polymorphism influenced neurochemical metabolism in 26 individuals with autism spectrum disorder. Individuals with the S/S genotype of the 5-HTTLPR polymorphism showed significantly lower levels of N-acetylaspartate/creatine in the right medial prefrontal cortex compared with those with the S/L genotype. (C) 2010 Elsevier Ireland Ltd. All rights reserved.

Link information
DOI
https://doi.org/10.1016/j.pscychresns.2010.04.015
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000280946700013&DestApp=WOS_CPL
ID information
  • DOI : 10.1016/j.pscychresns.2010.04.015
  • ISSN : 0925-4927
  • Web of Science ID : WOS:000280946700013

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