調恒明 (Komei Shirabe) - マイポータル

基本情報

所属: 山口県環境保健センター所長

学位: 医学(山口大学)

J-GLOBAL ID: 200901093179995847
researchmap会員ID: 1000051282

研究キーワード

研究分野

経歴

2007年4月 - 現在

山口県環境保健センター所長
2001年 - 2007年3月

大分大学医学部生化学助教授
1994年 - 2001年

大分医科大学医学部生化学第2講座助教授
1994年 - 2001年

Associate Professor, Department of Biochemistry : Oita Medical University
1988年 - 1994年

大分医科大学医学部生化学第2講座助手
1988年 - 1994年

Research fellow Department of Biochemistry : Oita Medical University
1985年 - 1988年

山口大学医学部生化学第講座助手
1985年 - 1988年

Research fellow Department of Biochemistry Yamaguch : University School of Medicine

学歴

論文

Burden of Human Metapneumovirus and Respiratory Syncytial Virus Infections in Asthmatic Children.

Furuta T, Hasegawa S, Mizutani M, Iwai T, Ohbuchi N, Kawano S, Tashiro N, Uchida M, Hasegawa M, Motoyama M, Sekino T, Nakatsuka K, Ichihara K, Shirabe K, Ohga S

The Pediatric infectious disease journal 37(11) 1107-1111 2018年5月査読有り
Phylogeny and Immunoreactivity of Norovirus GII.P16-GII.2, Japan, Winter 2016-17.

Koo Nagasawa, Yuki Matsushima, Takumi Motoya, Fuminori Mizukoshi, Yo Ueki, Naomi Sakon, Koichi Murakami, Tomomi Shimizu, Nobuhiko Okabe, Noriko Nagata, Komei Shirabe, Hiroto Shinomiya, Wataru Suzuki, Makoto Kuroda, Tsuyoshi Sekizuka, Akihide Ryo, Kiyotaka Fujita, Kazunori Oishi, Kazuhiko Katayama, Hirokazu Kimura

Emerging infectious diseases 24(1) 144-148 2018年1月査読有り
Genetic Analysis of Human Norovirus Strains in Japan in 2016-2017.

Koo Nagasawa, Yuki Matsushima, Takumi Motoya, Fuminori Mizukoshi, Yo Ueki, Naomi Sakon, Koichi Murakami, Tomomi Shimizu, Nobuhiko Okabe, Noriko Nagata, Komei Shirabe, Hiroto Shinomiya, Wataru Suzuki, Makoto Kuroda, Tsuyoshi Sekizuka, Yoshiyuki Suzuki, Akihide Ryo, Kiyotaka Fujita, Kazunori Oishi, Kazuhiko Katayama, Hirokazu Kimura

Frontiers in microbiology 9 1-1 2018年査読有り
Pulmonary inflammation and cytokine dynamics of bronchoalveolar lavage fluid from a mouse model of bronchial asthma during A(H1N1)pdm09 influenza infection

Yousuke Fujimoto, Shunji Hasegawa, Takeshi Matsushige, Hiroyuki Wakiguchi, Tamaki Nakamura, Hideki Hasegawa, Noriko Nakajima, Akira Ainai, Atsunori Oga, Hiroshi Itoh, Komei Shirabe, Shoichi Toda, Ryo Atsuta, Tsuneo Morishima, Shouichi Ohga

SCIENTIFIC REPORTS 7(1) 9128 2017年8月査読有り
Corrigendum to "Evaluation of sensitivity of TaqMan RT-PCR for rubella virus detection in clinical specimens" [J. Clin. Virol. 80 (2016) 98-101].

Okamoto K, Mori Y, Komagome R, Nagano H, Miyoshi M, Okano M, Aoki Y, Ogura A, Hotta C, Ogawa T, Saikusa M, Kodama H, Yasui Y, Minagawa H, Kurata T, Kanbayashi D, Kase T, Murata S, Shirabe K, Hamasaki M, Kato T, Otsuki N, Sakata M, Komase K, Takeda M

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 82 184-185 2016年9月査読有り
Molecular evolution of the capsid gene in human norovirus genogroup II.

Miho Kobayashi, Yuki Matsushima, Takumi Motoya, Naomi Sakon, Naoki Shigemoto, Reiko Okamoto-Nakagawa, Koichi Nishimura, Yasutaka Yamashita, Makoto Kuroda, Nobuhiro Saruki, Akihide Ryo, Takeshi Saraya, Yukio Morita, Komei Shirabe, Mariko Ishikawa, Tomoko Takahashi, Hiroto Shinomiya, Nobuhiko Okabe, Koo Nagasawa, Yoshiyuki Suzuki, Kazuhiko Katayama, Hirokazu Kimura

Scientific reports 6 29400-29400 2016年7月7日査読有り
Genetic analysis of human rotavirus C: The appearance of Indian-Bangladeshi strain in Far East Asian countries

Yen Hai Doan, Kei Haga, Akira Fujimoto, Yoshiki Fujii, Reiko Takai-Todaka, Tomoichiro Oka, Hirokazu Kimura, Shima Yoshizumi, Naoki Shigemoto, Reiko Okamoto-Nakagawa, Komei Shirabe, Hiroto Shinomiya, Naomi Sakon, Kazuhiko Katayama

INFECTION GENETICS AND EVOLUTION 41 160-173 2016年7月査読有り
Evaluation of sensitivity of TaqMan RT-PCR for rubella virus detection in clinical specimens

Kiyoko Okamoto, Yoshio Mori, Rika Komagome, Hideki Nagano, Masahiro Miyoshi, Motohiko Okano, Yoko Aoki, Atsushi Ogura, Chiemi Hotta, Tomoko Ogawa, Miwako Saikusa, Hiroe Kodama, Yoshihiro Yasui, Hiroko Minagawa, Takako Kurata, Daiki Kanbayashi, Tetsuo Kase, Sachiko Murata, Komei Shirabe, Mitsuhiro Hamasaki, Takashi Kato, Noriyuki Otsuki, Masafumi Sakata, Katsuhiro Komase, Makoto Takeda

JOURNAL OF CLINICAL VIROLOGY 80 98-101 2016年7月査読有り
Predicting genotype compositions in norovirus seasons in Japan

Yoshiyuki Suzuki, Yen Hai Doan, Hirokazu Kimura, Hiroto Shinomiya, Komei Shirabe, Kazuhiko Katayama

MICROBIOLOGY AND IMMUNOLOGY 60(6) 418-426 2016年6月査読有り
An Improved Multiplex Real-Time SYBR Green PCR Assay for Analysis of 24 Target Genes from 16 Bacterial Species in Fecal DNA Samples from Patients with Foodborne Illnesses

Jun Kawase, Yoshiki Etoh, Tetsuya Ikeda, Keiji Yamaguchi, Masanori Watahiki, Tomoko Shima, Mitsuhiro Kameyama, Kazumi Horikawa, Hiroshi Fukushima, Ryoichi Goto, Komei Shirabe

JAPANESE JOURNAL OF INFECTIOUS DISEASES 69(3) 191-201 2016年5月査読有り
Phylogenetic and Geographic Relationships of Severe Fever With Thrombocytopenia Syndrome Virus in China, South Korea, and Japan

Tomoki Yoshikawa, Masayuki Shimojima, Shuetsu Fukushi, Hideki Tani, Aiko Fukuma, Satoshi Taniguchi, Harpal Singh, Yuto Suda, Komei Shirabe, Shoichi Toda, Yukie Shimazu, Taro Nomachi, Mutsuyo Gokuden, Toshiharu Morimitsu, Katsuyuki Ando, Akira Yoshikawa, Miki Kan, Marina Uramoto, Hideo Osako, Kouji Kida, Hirokazu Takimoto, Hiroaki Kitamoto, Fumio Terasoma, Akiko Honda, Ken Maeda, Toru Takahashi, Takuya Yamagishi, Kazunori Oishi, Shigeru Morikawa, Masayuki Saijo

JOURNAL OF INFECTIOUS DISEASES 212(6) 889-898 2015年9月査読有り
Molecular Evolution of the Capsid Gene in Norovirus Genogroup I.

Kobayashi M, Yoshizumi S, Kogawa S, Takahashi T, Ueki Y, Shinohara M, Mizukoshi F, Tsukagoshi H, Sasaki Y, Suzuki R, Shimizu H, Iwakiri A, Okabe N, Shirabe K, Shinomiya H, Kozawa K, Kusunoki H, Ryo A, Kuroda M, Katayama K, Kimura H

Scientific reports 5 13806 2015年9月査読有り
Molecular evolution of haemagglutinin (H) gene in measles virus.

Hirokazu Kimura, Mika Saitoh, Miho Kobayashi, Haruyuki Ishii, Takeshi Saraya, Daisuke Kurai, Hiroyuki Tsukagoshi, Komei Shirabe, Atsuyoshi Nishina, Kunihisa Kozawa, Makoto Kuroda, Fumihiko Takeuchi, Tsuyoshi Sekizuka, Hisanori Minakami, Akihide Ryo, Makoto Takeda

Scientific reports 5 11648-11648 2015年7月1日査読有り
Molecular evolution of the VP1, VP2, and VP3 genes in human rhinovirus species C

Makoto Kuroda, Shoichi Niwa, Tsuyoshi Sekizuka, Hiroyuki Tsukagoshi, Masaru Yokoyama, Akihide Ryo, Hironori Sato, Naoko Kiyota, Masahiro Noda, Kunihisa Kozawa, Komei Shirabe, Takashi Kusaka, Naoki Shimojo, Shunji Hasegawa, Kazuko Sugai, Masatsugu Obuchi, Masato Tashiro, Kazunori Oishi, Haruyuki Ishii, Hirokazu Kimura

SCIENTIFIC REPORTS 5 8185 2015年2月査読有り
[Current status of bacteriological studies at prefectural and municipal public health institutes in Japan].

Shinomiya H, Seto K, Kawase J, Arikawa K, Funatogawa K, Suzuki M, Kubota H, Shirabe K

Nihon saikingaku zasshi. Japanese journal of bacteriology 70(2) 309-318 2015年査読有り
[Fact-finding survey on regional healthcare services for patients with epilepsy based on a questionnaire administered to public health centers in Japan].

Fujii M, Ishimaru Y, Takahashi H, Egami H, Nishida H, Oka S, Shirabe K

[Nihon koshu eisei zasshi] Japanese journal of public health 62(10) 609-616 2015年査読有り
Comparison of Two Methods of Bacterial DNA Extraction from Human Fecal Samples Contaminated with Clostridium perfringens, Staphylococcus aureus, Salmonella Typhimurium, and Campylobacter jejuni

Jun Kawase, Morito Kurosaki, Yuta Kawakami, Takashi Kashimoto, Yoshie Tsunomori, Koji Sato, Tetsuya Ikeda, Keiji Yamaguchi, Masanori Watahiki, Tomoko Shima, Mitsuhiro Kameyama, Yoshiki Etoh, Kazumi Horikawa, Hiroshi Fukushima, Ryoichi Goto, Komei Shirabe

JAPANESE JOURNAL OF INFECTIOUS DISEASES 67(6) 441-446 2014年11月査読有り
Cytokine profile of bronchoalveolar lavage fluid from a mouse model of bronchial asthma during seasonal H1N1 infection

Shunji Hasegawa, Hiroyuki Wakiguchi, Seigo Okada, Yu Gui Kang, Nao Fujii, Masanari Hasegawa, Hideki Hasegawa, Akira Ainai, Ryo Atsuta, Komei Shirabe, Shoichi Toda, Midori Wakabayashi-Takahara, Tsuneo Morishima, Takashi Ichiyama

CYTOKINE 69(2) 206-210 2014年10月査読有り
Genetic analysis of attachment glycoprotein (G) gene in new genotype ON1 of human respiratory syncytial virus detected in Japan

Hiroyuki Tsukagoshi, Hajime Yokoi, Miho Kobayashi, Izumi Kushibuchi, Reiko Okamoto-Nakagawa, Ayako Yoshida, Yukio Morita, Masahiro Noda, Norio Yamamoto, Kazuko Sugai, Kazunori Oishi, Kunihisa Kozawa, Makoto Kuroda, Komei Shirabe, Hirokazu Kimura

MICROBIOLOGY AND IMMUNOLOGY 57(9) 655-659 2013年9月査読有り
Analysis of bronchoalveolar lavage fluid in a mouse model of bronchial asthma and H1N1 2009 infection

Seigo Okada, Shunji Hasegawa, Hideki Hasegawa, Akira Ainai, Ryo Atsuta, Kenzo Ikemoto, Kohsuke Sasaki, Shoichi Toda, Komei Shirabe, Midori Takahara, Sawako Harada, Tsuneo Morishima, Takashi Ichiyama

CYTOKINE 63(2) 194-200 2013年8月査読有り

もっとみる

MISC

Chemokine signaling regulates sensory cell migration in zebrafish

Q Li, K Shirabe, JY Kuwada

DEVELOPMENTAL BIOLOGY 269(1) 123-136 2004年5月
Chemokine signaling regulates sensory cell migration in zebrafish

Q Li, K Shirabe, JY Kuwada

DEVELOPMENTAL BIOLOGY 269(1) 123-136 2004年5月
Identification and characterization of a soluble cadherin-7 isoform produced by alternative splicing

R Kawano, N Matsuo, H Tanaka, M Nasu, H Yoshioka, K Shirabe

JOURNAL OF BIOLOGICAL CHEMISTRY 277(49) 47679-47685 2002年12月
Identification and characterization of a soluble cadherin-7 isoform produced by alternative splicing

R Kawano, N Matsuo, H Tanaka, M Nasu, H Yoshioka, K Shirabe

JOURNAL OF BIOLOGICAL CHEMISTRY 277(49) 47679-47685 2002年12月
CEPU-1, an immunoglobulin superfamily molecule, has cell adhesion activity and shows dynamic expression patterns in chick embryonic spinal cord

Y Kimura, K Shirabe, M Fukushima, M Takeshita, H Tanaka

NEUROSCIENCE RESEARCH 34(4) 245-255 1999年9月
Electrostatic interaction between NADH-cytochrome b5 reductase and cytochrome b5 studied by site-directed mutagenesis

Komei Shirabe, Takushi Nagai, Toshitsugu Yubisui, Masazumi Takeshita

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology 1384(1) 16-22 1998年4月23日
Role of carboxyl residues surrounding heme of human cytochrome b(5) in the electrostatic interaction with NADH-cytochrome b(5) reductase

M Kawano, K Shirabe, T Nagai, M Takeshita

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 245(3) 666-669 1998年4月
Identification of alternative first exons of NADH-cytochrome b(5) reductase gene expressed ubiquitously in human cells

MJ Du, K Shirabe, M Takeshita

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 235(3) 779-783 1997年6月
Lack of promotion of colon carcinogenesis by high-oleic safflower oil

M Takeshita, H Ueda, K Shirabe, Y Higuchi, S Yoshida

CANCER 79(8) 1487-1493 1997年4月
Commitment of motoneuron progenitors of chick embryo along the anterior-posterior axis

H Tanaka, M Fukushima, K Ohta, Y Kimura, A Sudo, K Shirabe, M Takeshita

DEVELOPMENTAL NEUROSCIENCE 19(1) 106-111 1997年1月
Analysis by Fourier transform infrared spectroscopies of protein structures of soluble NADH-cytochrome bs reductases prepared by site-directed mutagenesis

Biospectro scopy 3 215 1997年
Effect of dietary high-oleic safflower oil on chemically induced colon and mammary carcinogenesis

Food factors for cancer prevention Springer-Verlag, Tokyo. 495 1997年
Differential display of mRNAs from thoracic and lumbar spinal cord of 4-day chick embryo

Journal of Neurochemistry 65(5) 144 1995年
High incidence of Haemophilus influenzae in nasopharyngeal secretions and middle ear effusions as detected by polymerase chain reaction

Journal of Clinical Microbiology 33(7):1835-1838. 1995年
Transient kinetics of intracomplex electron transfer in the human cytochrome b₅ reductase-cytochrome b₅ system : NAD⁺ modulates protein-protein binding

Archives of Biochemistry and Biophysics 318(2) 457-464 1995年
A novel point mutation in a 3 splice site of the NADH-cytochrome b₅ reductase gene result in immunologically undetectable enzyme and impaired NADH-dependent ascorbate regeneration in cultured fibroblasts of a patient with typeII hereditary m・・・

American Journal of Human Genetics 1995年
CLONING AND NUCLEOTIDE-SEQUENCE OF A CDNA OF THE HUMAN ERYTHROCYTE NADPH-FLAVIN REDUCTASE

K CHIKUBA, T YUBISUI, K SHIRABE, M TAKESHITA

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 198(3) 1170-1176 1994年2月
AN IN-FRAME DELETION OF CODON-298 OF THE NADH-CYTOCHROME B(5) REDUCTASE GENE RESULTS IN HEREDITARY METHEMOGLOBINEMIA TYPE-II (GENERALIZED TYPE) - A FUNCTIONAL IMPLICATION FOR THE ROLE OF THE COOH-TERMINAL REGION OF THE ENZYME

K SHIRABE, Y FUJIMOTO, T YUBISUI, M TAKESHITA

JOURNAL OF BIOLOGICAL CHEMISTRY 269(8) 5952-5957 1994年2月
ANALYSIS OF MUTANT NADH-CYTOCHROME-B5 REDUCTASE - APPARENT TYPE-III METHEMOGLOBINEMIA CAN BE EXPLAINED AS TYPE-I WITH AN UNSTABLE REDUCTASE

T NAGAI, K SHIRABE, T YUBISUI, M TAKESHITA

BLOOD 81(3) 808-814 1993年2月
Role of Lys-110 of human NADH-cytochrome b₅ reductase in NADH binding as probed by site-directed mutagenesis

FEBS LETTERS 322,30-32 1993年

もっとみる

書籍等出版物

ウイルス感染症の検査・診断スタンダード

田代眞人, 牛島廣治 (担当:分担執筆)

羊土社 2011年6月
イオンチャネル型コリシンの作用機構

新生化学実験講座(日本生化学会編) 1992年
Mutagenesis of the COOH-terminal Channel Domain of Colicin E1 Affecting the Ion Selectivity of the Channel

Transport Through Membrane : Carriers, Channels and Pumps 1988年
Structural Analysis of NADH-Cytochrome (b5) Reductase in Relation to Hereditary Methemoglobinemia

The Red Cell 1988年

調恒明

基本情報

研究キーワード

研究分野

経歴

学歴

論文

MISC

書籍等出版物

所属学協会

共同研究・競争的資金等の研究課題

メニュー